The PiTT-CMU MSTP NewSleTTer - University of Pittsburgh :: MSTP

The Pitt-CMU MSTP Newsletter
Volume IX, No. 2
Spring 2011
Contents
2010-11 Second
Look, 1
2011 Match, 1, 4
Alumni Profile:
Elena Hawryluk
(‘09), 2, 3
Director’s Corner,
3
MSTP Students
in Action: IACT
Targets Healthcare
Technology 2, 3
Ethics: Social
Networking in
Medicine, 5
Student
Accolades, 6
Student
Announcements, 6
Recently Awarded
PhDs and
Newly Funded
Fellowships, 6
Student
Publications, 7
Operation Second Look: Mission Success
27 prospective MSTP students revisit Pittsburgh to experience the Pitt-CMU
MSTP through the eyes of fellow graduate students
The MSTP Second Look
committee is happy to
report the successful
completion of our 2010-11
recruitment efforts! This
year marked the first time
piloting a new approach to
the traditional Second Look.
In order to allow students to
better explore the research
opportunities available to
them at both the University
of Pittsburgh and Carnegie-
Mellon, the MSTP Second
Look committee combined
its efforts with graduate
program recruitment
weekends to offer Second
Look experiences tailored for prospective
students in different scientific disciplines.
An evening of MSTP activities kicked
off each of these recruitment weekends,
including coffee in Oakland with students, wine
and cheese with the MSTP leadership, a panel
discussion with current MSTP students about
the program, as well as various social activities.
For each visit, a sumptuous feast was prepared
by the committee co-chairs and hosted at one
of the student’s homes. This was an excellent
opportunity for prospective students to relax and
learn the ins-and-outs of the Pitt MSTP firsthand
from our student body. The following days, hosted
by the graduate programs, allowed students to
learn more about research opportunities in the
respective graduate departments and to have
one-on-one meetings with department faculty.
Our pilot year of combining Second Look with
graduate department recruitment weekends
prompted a strong turnout of 27 prospective
student attendees over the course of the
recruitment efforts. We are looking forward
to learning more about the success of these
weekends when we meet our new students this
summer!
Above: Judson Englert (MS4, left) and Corrine Kliment (MS4, right) share their happiness
at a successful couples’ match. (Photo credit - Liang I. Kang, G3)
A Match Made In Pittsburgh
2011 marked an exceptional match year
for MSTP MS4s
Speaking as a lowly G2 it was heartening, to
say the very least, to watch our esteemed MS4
class match this year. As always, I was out to
cheer on my upperclassmen as they opened up
that fabled envelope. A ray of hope for those of
us working diligently towards our theses or taking
the USMLE boards.
Every year I am energized by this ritual,
despite the bittersweet knowledge that we will no
longer share our program with those moving on
to bigger and better things. As always, this was
a banner year for the MSTP.
This year our students matched at the
country’s most prestigious institutions, in the
most competitive specialties, and with uniform
success. But these are not the most important
aspect of this year’s match. As epitomized
by the photo above, our MS4s matched with
the joy and pure emotion that can only come
with the culmination of six-plus years of effort.
Congratulations to all the MS4s, you will be
missed.
Upcoming Events,
8
- Daniel Bishop, MS2 and Mark Langhans,
MS2
- Alanna Peterson, G2
see page 4 for Match Results
1

2
Profiles in Medicine: Dr. Elena Hawryluk
An alumna from the Class of 2009 advises future students on selecting a mentor, choosing a
clinical specialty, and finding a balance between research and clinic in dermatology
D r . Elena Hawryluk is a
2009 Pitt MSTP alumna. She
is currently a resident in the
Harvard Dermatology Residency
Program in Boston, Mass.
Below, she reflects on her Pitt
experience, talks about her
current position, and shares
advice for future Pitt-CMU MSTP
graduates.
Q: How did you decide on a career
as an MD/PhD
A: I became interested in the MD/
PhD career through the mentorship
and advice of several researchers
I was fortunate to work with during
college. I studied computer
science and was involved in
research projects at the interface
of technology and medicine, such
as a robotic-assisted surgery
project at Carnegie Mellon, and a
spectral imaging analysis project
that involved pathology samples.
I worked for mentors that gave me
exposure to clinical medicine and
the exciting prospect of combining
research and clinical activities.
Q: How did you pick your thesis lab
and mentor
A: First, I decided that I wanted a
strong basic science foundation
during graduate school, regardless
of scientific subject. I spoke
with many different people, from
graduate students to department
chairs, and even Dr. Levine, to
hear their perspectives on good
mentors and laboratories that
would help me accomplish my
goals. I did three rotations, each
in a different department, which
gave me excellent exposure to
different areas and techniques,
before joining Dr. Apodaca’s lab
in cell biology. I had a wonderful
experience in Dr. Apodaca’s
laboratory—he is an outstanding
mentor!
Q: How did you choose your
specialty
A: Selecting a medical specialty
was difficult because I enjoyed
all of my clinical experiences.
I chose my specialty while in
graduate school and found the
LCC to be pivotal in helping me to
determine my path. I had a great
longitudinal clerkship experience in
otology, and then was exposed to
dermatology, which I found to be a
perfect fit for me.
Q: Please tell me a little bit about
what your day is like now.
A: We have a daily didactic in the
morning, followed by outpatient
clinics or consults, depending
on the rotation. I have protected
elective time to explore many
see page 3, Hawryluk
Watch Out Bill Gates, Here Comes the IACT
Students from the MSTP along with University of Pittsburgh, Carnegie Mellon and Duquesne
graduate students spur a grassroots innovation movement to improve healthcare technology
Where do students in business,
medicine, science, and engineering
sit down with Pittsburgh’s most
talented and experienced industry
professionals to develop innovative
healthcare solutions
They do so at IACT—
Industry Academics Clinicians
Together—an organization led by
Pitt and CMU graduate students
whose mission is to spur technology
innovation within healthcare and
improve the region’s economy.
Cofounders include three of our
own MSTP students, Daniel Bishop
(MS2), Jim Fisher (MS2), and
Jason Sanders (G1), and other
students from Pitt, CMU, and
Duquesne University.
IACT was formed in July of
2010 and since then has engaged
over 120 students and professionals
in workshops and competitions. It
has received financial support
and hosted speakers from many
university-affiliated centers and
local business accelerators. Thus
far, IACT events have focused
on two topics that reflect the
strengths of the local academic and
business communities, “Healthcare
Technologies for an Aging America”
and “Surgical Technology.”
IACT was formed first with
the knowledge that individuals
in general, and students in
particular, tend to stay within their
own thought circles and that this
hinders progress. The theory
behind IACT is akin to that behind
the MSTP—that multidisciplinary
training hastens translation.
Subsequently, events
are specifically structured to mix
students and professionals from
different backgrounds, effectively
forcing them out of their comfort
zone to solve a large problem in
healthcare using technology. For
example, at an event a medical
student from Pitt may be partnered
with a computer science student
from CMU, an MBA student at
Pitt, the CEO of a local biotech
company, and a geriatrician at
UPMC, and all are charged with
creating a technology-based
see page 3, IACT

In the past I have used this venue to
highlight developments in the Pittsburgh
MSTP, but the past couple years of
economic changes push me to address
more global issues related to physician
scientist training. The various economic
bubbles (beginning with the dot-com
bubble and continuing with the housing
bubble) have burst. In conjunction
with tremendously expensive military
ventures and a severe decline in our
economy, these economic changes
have shaken our country. We should
have done the numbers in 2009 and
better anticipated the implications of
these changes for research, but most
of us buried our collective heads in the
sand and hoped the economy would
turn around before the implications of
our financial woes would be evident in
research budgets.
Well, despite a large stimulus
package, the economy remains sluggish
and tax revenues are down. Severe
cuts are being made and pain that was
especially pronounced in the private
sector in 2009 has reached publicly
funded research. NIH is proving to
be one of the biggest casualties. This
deep in the financial hole it is difficult
to imagine a rosy horizon in the near
future. It may be longer than a decade
before discretionary funding recovers to
a point where NIH funded research will
have the leverage it has enjoyed in the
recent past.
What does this mean for training
physician scientists I think the bottom
line is that competition is
going to be more than fierce.
To be successful, freshly
minted MD/PhDs are not
going to prosper with just
good science and clinical
skills, but will also need a set
of well-honed survival skills. Granting
from NIH will still be important; however,
broader horizons must be sought.
Alternative sources of funding and
focused collaborations may make the
difference between viable careers and
frustrating reassignment.
Historically, much of Pittsburgh’s
MSTP professional development has
been focused on the NIH. While skills
learned in writing NIH grants have broad
applicability, we are clearly charged
with having to expand the training to
Director’s Corner
A Message From Clayton Wiley, MD, PhD
Associate Dean, Director of MSTP
encompass new funding and research
modes. The good news is that in the past
12 years, we are committed to creating
a real training program that is robust
and adaptable, a great foundation for
tweaking and creating a training engine
to prepare for the new world. We plan
to face the upcoming challenges for
physician scientists head-on by not just
preparing students for these challenges
through training, but hopefully teaching
them to anticipate frustrations and think
outside the box to find solutions.
from page 2, Hawryluk
research opportunities as well
as longitudinal academic time to
pursue these interests during the
year.
Q: How do you currently balance
family time and career, or how do
you see yourself balancing these
in the future
A: I am fortunate to be in a field
like dermatology which will allow
me to have a focused outpatient
clinic and very modular time to
explore my academic and research
interests, in addition to my career
and family time.
Q: Where do you see yourself in
10 years
A: In an academic center, with clinical
and research responsibilities.
Q: Do you have any advice for
MSTP students
A: Explore your options before
making decisions, I am very happy
to have gathered advice and
learned from the senior MSTP
students before joining a lab.
These same senior MSTP trainees
continue to be friends and mentors
to me.
- Niyathi Hegde, G1
Dr. Elena Hawryluk can be reached at
elena.hawryluk@gmail.com
from page 2, IACT
innovation to improve the wellbeing
of older adults.
IACT was also created to
enable students to pursue ventures
that otherwise might not find
support. Whether a student at Pitt
or CMU, in medicine or electrical
engineering or management,
it is often difficult to capitalize
on an idea because the world
looks at you as “just a student.”
Nonetheless, individual students or
teams of students have produced
groundbreaking ideas worth
supporting.
IACT serves as a meeting
place for students working in
this vein so they can collectively
support each other. Importantly, it
also links these students to funding
and consulting services in the
region so students can build their
ventures in the real world.
The founders of IACT have
a vision to make Pittsburgh a
nationally-recognized force in
healthcare innovation, and make
students a part of that force.
We invite you to learn more
about IACT, including upcoming
events, at www.iactpgh.com.
- Daniel Bishop, MS2 and Jason
Sanders, G1
3

Match Day Results
Congratulations To Our Soon To Be Doctor-Doctors!
Mandar Aras — Internal Medicine, Duke University
Mehret Birru — Internal Medicine/Womens Health, University of Pittsburgh
Frank Cackowski — Internal Medicine, University of Michigan
Sherrie Divito — Dermatology, Harvard University
Judson Englert — Internal Medicine, Harvard University
Corrine Kliment — Internal Medicine, Harvard University
Cyrus Raji — Radiology-Diagnostic, UCLA
Melanie Ruffner — Pediatrics, Children’s Hospital of Philadelphia
Jeremy Tilstra — Internal Medicine, University of Pittsburgh
Peter Vosler — Otolaryngology, University of Pittsburgh
Genevieve Woodard — Radiology-Diagnostic, UCSF
Right: Sherrie Divito (MS4) opens her
match letter to Harvard University. Bottom
Left: Mehret Birru (MS4) announces her
match to the University of Pittsburgh. Bottom
Right: Mandar Aras (MS4) announces
his match to Duke University. (Photo credits
- Liang I. Kang, G3)
4

Spotlight on Current Ethical Dilemmas:
What Role, If Any, Does Social Networking
plAy in Modern Medicine
Technological advancements are happening at an amazing
speed in our generation, enabling social networking sites to
become increasingly accessible. Have you seen the Best Buy
commercial with Ozzy Osbourne and Justin Bieber boasting
about mobile internet speed upgrades Are you waiting with
baited breath for the iPad 2 Were you behaving like a kid in
a candy store when the iPhone 4 became available on the Verizon
network I have to confess that I personally think “two
networks are better than one.”
At the end of last year, 31 percent of Americans owned
smart phones and over four billion iPads were sold (Google.
com). Whether it be via a smartphone, tablet, or notebook
computer, the average medical student has internet access 24
hours a day, seven days a week. You can video chat, tweet,
update Facebook statuses, share pictures, and blog to your
hearts content. What is more, network providers like T-Mobile ©
and AT&T TM often advertise access to social networking sites
as a feature of their devices. Awesome… right
Example from one of
my Facebook friends:
…. This lady came to
ER because she saw
raccoons in her garbage
this morning and
she feels “a little off”
so she would like to be
checked for rabies
-PHYSICIAN at Wesley
Medical Center, CONN
9 a.m. EST on Jan. 23
via iPhone
Neither of the posts contain common patient identifiers
(see below), but the postings themselves leave date,
time, and location information. Moreover, the comments
that follow such posts can be explicit and mean.
Maybe not.
In spite of the fact that
Facebook and MySpace
activity can be used as evidence
in a court of law, no
one has stopped to ask if
such accessibility to social
networking is even necessary.
Even though it gives
me great delight to share
that Charlie Sheen just set
the “fastest time to reach 1 million followers” Guinness World
Record this week (CNN Tech) after a string of purely comical
tweets, many postings on Facebook are not laughing matters.
Dr. Richard Steinman brought up the following submission
from NY Times The Ethicist column:
Some of my Facebook friends are medical students
who post cellphone pictures of patients with what these friends
believe to be comical maladies, with captions like “A 5-foot-9
Hispanic male walks into a bar . . .” under a picture of a patient
with a piece of rebar piercing his abdomen. The postings don’t
include faces or names but still seem questionable. Doesn’t
this violate patient privacy
-NAME WITHHELD, NEW YORK
Medical students getting into trouble on Facebook is
not earth-shattering news. What is alarming is the frequency
at which incidents like the one described above are occurring.
In truth, it is not a rarity for medical students to post pictures of
themselves in the hospital with patients or to describe patients
encountered on any given day.
As a friendly reminder, the HIPAA Privacy Rule protects
all individually identifiable health information held or
transmitted by a covered entity or its business associate,
in any form or media, whether electronic, paper, or oral.
Identifiable health information
includes demographic
data and relates to:
•the individual’s past,
present, or future physical
or mental health or condition
•the provision of health
care to the individual
•the past, present, or future
payment for the provision
of health care to the
individual, and that identifies
the individual or for which there is a reasonable basis
to believe can be used to identify the individual.
policy.
See www.hhs.gov/ocr/privacy/ for the complete
Common patient identifiers include but are not limited
to name, address, birth date, or Social Security Number.
Questions to think about: Would it be reasonable to believe
information accessible to 1,000 Facebook friends can be
used to identify an individual And is it okay to share patient
information as long as the patients are not identifiable With
more than 500 million active Facebook users, half of which
log on every single day, it might be wise to post with caution.
- Natasha Corbitt, G2
5

Student Accolades
Congratulations to our newly funded Fellowship!
Anoopum Gupta
Cognitive Maps and Novel Behavioral Sequences in the Hippocampus (F30, Mentor: David Touretzky,
PhD)
Congratulations, Doctor! Recently Awarded PhDs
Matthew Boyer
DNMT3b’s role in hematopoietic stem cells. Advisor: Tao Cheng, MD (molecular genetics and
developmental biology, Pitt)
Michael Leibowitz
Regulation of antigen processing machinery component expression in head and neck cancer by signal
transducers and activators of transcription and SRC homology-2 domain-containing phosphotase.
Advisor: Robert Ferris, MD, PhD (immunology, Pitt)
Joseph Vella
The role of stress resistance in cell transplantation efficacy for muscle regeneration. Advisor: Johnny
Huard, PhD (bioengineering, Pitt)
David Wheeler
The PDZ adaptor, NHERF1, organizes and regulates protein complexes at the cell membrane. Advisor:
Guillermo Romero, PhD (molecular pharmacology, Pitt)
Student Announcements
Judson M. Englert and
Corrine R. Kliment
will be wed on
Saturday, April 9, 2011.
Alanna C. Peterson and
Erin E. Childs got engaged
on Wednesday, March 9,
2011.
David S. Wheeler and
Karen L. Condon
got engaged on Saturday,
March 19, 2011.
All the Best To the
Happy Couples!!!
Brandon Alexander Tilstra
(8 lb 7 oz) was born to Sarah
and Jeremy Tilstra (MS4) on
Friday, March 11, 2011.
6

New MSTP Student Publications through March 2011
Afrazi A, Sodhi CP, Richardson W, Neal M, Good M, Siggers
R, Hackam DJ (2010). New Insights into the Pathogenesis
and Treatment of Necrotizing Enterocolitis: Toll-like Receptors
and Beyond. Pediatr Res. Dec 3. [Epub ahead of print;
PMID: 21135755]
Wells A, Chao Y, Grahovac J, Wu Q, Lauffenburger DA
(2010). Cell motility in carcinoma metastasis as modulated
by switching between epithelial and mesenchymal phenotypes.
Frontiers in Biosciences (In press)
Isse K, Grama K, Abbott IM, Lesniak A, Lunz JG, Lee WM,
Specht S, Corbitt N, Mizuguchi Y, Roysam B, Demetris
AJ (2010). Adding value to liver (and allograft) biopsy
evaluation using a combination of multiplex quantum dot
immunostaining, high resolution whole-slide digital imaging,
and automated image analysis. Clin Liver Dis. 14(4):669-
85. [PMID: 21055689]
Glorioso C, Sibille E (2010). Between destiny and disease:
genetics and molecular pathways of human central nervous
system aging. Prog Neurobiol. Dec 1. [Epub ahead of print;
PMID: 21130140].
Johnson CA Jr, Wearden PD, Kocyildirim E, Maul TM, Woolley
JR, Ye S-H, Strickler EM, Borovetz HS, Wagner WR.
Platelet Activation in ovines undergoing sham surgery or
implant of the second generation PediaFlow pediatric
ventricular assist device. Artif Organs- (Accepted)
Kang J, Steward RL, Kim YT, Schwartz RS, Leduc PR,
Puskar KM (2011). Response of an actin filament network
model under cyclic stretching through a coarse grained
Monte Carlo approach. J Theor Biol. Jan 15. [Epub ahead
of print; PMID: 21241710]
Kliment, CR, Oury, TD (2011). Extracellular superoxide dismutase
protects cardiovascular syndecan-1 from oxidative
shedding. Free Radic Biol Med. Feb 17 [Epub ahead of
print; PMID:213344435]
Donthamsetty S, Bhave VS, Kliment C, Bowen WC, Mars
WM, Bell AW, Stewart RE, Orr A, Wu C, Michalopoulos GK
(2011). Excessive hepatomegaly of mice with hepatocytetargeted
elimination of integrin linked kinase following treatment
with 1,4-bis [2-(3,5-dichaloropyridyloxy)] benzene.
Hepatology. Feb;53(2):587-95. [PMID: 21274879]
Wang H, Nora GJ, Ghodke H, Opresko PL (2011). Single
Molecule Studies of Physiologically Relevant Telomeric
Tails Reveal POT1 Mechanism for Promoting Gquadruplex
Unfolding. J Biol Chem. Mar 4; 286(9):7479-89. [PMID:
21183684]
Patel VP and Chu CT (2011). Nuclear transport, oxidative
stress, and neurodegeneration. Int J Clin Exp Pathol. Mar;
4(3):215-229.
Pandiyan P, Conti HR, Zheng L, Peterson AC, Mathern DR,
Hernández-Santos N, Edgerton M, Gaffen SL, Lenardo MJ
(2011). CD4+CD25+Foxp3+ Regulatory T Cells Promote
Th17 Cells In Vitro and Enhance Host Resistance in Mouse
Candida albicans Th17 Cell Infection Model. Immunity. Mar
25;34(3):422-434. [PMID:21435589]
Du Y, Roh DS, Funderburgh ML, Mann MM, Marra KG,
Rubin JP, Li X, Funderburgh JL (2010). Adipose-derived
stem cells differentiate to keratocytes in vitro. Mol Vis. Dec
10;16:2680-9. [PMID: 21179234]
Sanders JL, Iannaccone A, Boudreau RM, Conley YP,
Opresko PL, Hsueh W-C, Cummings SR, Cawthon RM,
Harris TB, Nalls MA, Kritchevsky SB, Newman AB, for
the Health ABC Study (2011). The association of cataract
with leukocyte telomere length in older adults: defining a
new marker of aging. J Gerontol A Biol Sci Med Sci. (Accepted)
Prince CT, Secrest AM, Mackey RH, Arena VC, Kingsley
LA, Orchard TJ (2011). Pulse wave analysis and prevalent
cardiovascular disease in type 1 diabetes. Atherosclerosis.
Dec; 213(2):469-74. [PMID: 20880527]
McGuire ST, Secrest AM, Andrulonis R, Ferris LK (2010).
Surveillance of patients for early detection of melanoma:
Patterns in dermatologist vs. patient discovery. Arch Dermatol
(Accepted)
Secrest AM, Becker DJ, Kelsey SF, LaPorte RE, Orchard TJ
(2011). Characterizing sudden death and dead-in-bed syndrome
in type 1 diabetes: Analysis from 2 childhoodonset
type 1 diabetes registries. Diabet Med. Mar; 28(3): 293-300.
[PMID: 21309837]
Secrest AM, Costacou T, Gutelius B, Miller RG, Songer TJ,
Orchard TJ (2011). Association of socioeconomic status
with mortality in type 1 diabetes: the Pittsburgh Epidemiology
of Diabetes Complications (EDC) Study. Ann Epidemiol
(Accepted)
Shin SS, Bray ER, Zhang CQ, Dixon CE (2011). Traumatic
brain injury reduces striatal tyrosine hydroxylase activity
and potassium-evoked dopamine release in rats. Brain
Res. Jan 19;1369:208-15. [PMID: 21047500]
Sturman DA and Moghaddam B (2011). Reduced neuronal
inhibition and coordination of adolescent prefrontal cortex
during motivated behavior. J Neurosci Jan 26;31 (4):1471-
1478. [PMID:21273431]
Thompson MD, Awuah P, Singh S, Monga SP (2010).
Disparate cellular basis of improved liver repair in betacatenin-overexpressing
mice after long-term exposure to
3,5-diethoxycarbonyl-1,4-dihydrocollidine. Am J Pathol.
Oct;177(4):1812-22. [PMID: 20813968]
Thompson MD, Dar MJ, Monga SP (2010). Pegylated interferon
alpha targets Wnt signaling by inducing nuclear
export of β-catenin. J Hepatol. Oct 29. [Epub ahead of
print; PMID: 21093092]
Wilson ME, Boumaza I, Lacomis D, Bowser R (2010). Cystatin
C: a candidate biomarker for amyotrophic lateral sclerosis.
PLoS One. Dec 9;5 (12):e15133. [PMID: 21151566]
Wong JL, Mailliard RB, Moschos SJ, Edington H, Lotze MT,
Kirkwood JM, Kalinski P (2011). Helper activity of natural
killer cells during the dendritic cell-mediated induction of
melanoma-specific cytotoxic T cells. J Immunother. 34:270-
278. [PMID: 21389871]
Woodard GA, Brooks MM, Barinas-Mitchell E, Mackey RH,
Matthews KA, Sutton-Tyrrell K (2010). Lipids, menopause,
and early atherosclerosis in Study of Women’s Health
Across the Nation Heart women. Menopause. Nov 19.
[Epub ahead of print; PMID: 21107300]
7

University of Pittsburgh-Carnegie Mellon University
Medical Scientist Training Program
526 Scaife Hall
3550 Terrace Street
Pittsburgh, PA 15261
Upcoming Events
April 2011
30: Spring Term Ends
May 2011
2: Summer Term Begins
17th: MSTP Workshop, 5 p.m. (University Club)
23: Pitt SOM Graduation
July 2011
19: MSTP Workshop, 5 p.m. (S100A BST)
August 2011
8: Summer Term Ends
19-22: MSTP Annual Retreat
29: Fall Term Begins
September 2011
5: Labor Day (University Closed)
The University of Pittsburgh and Carnegie
Mellon University’s MSTP Newsletter
Program Staff
Director: Clayton Wiley, MD, PhD
Codirectors: Richard Steinman, MD, PhD
George Stetten, MD, PhD
Administrative Director: Manjit Singh, PhD
Program Manager: Justin Markuss
Newsletter Staff
Article and Layout Editor: Alanna Peterson (G2)
Visit our website for more details about the
program, including information about students
and alumni:
www.mdphd.pitt.edu
Comments and submissions are encouraged!
This newsletter is written and assembled by
students of the MSTP. The views represented in
this newsletter do not necessarily reflect those
of the University of Pittsburgh, the University
of Pittsburgh School of Medicine, or Carnegie
Mellon University.
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77933-0511