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10th International Rotavirus Symposium ... - Sabin Vaccine Institute

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Immunization<br />

schedule<br />

The benefits of rotavirus vaccine<br />

outweigh the potential risks<br />

Potential<br />

vaccine associated<br />

intussusception<br />

deaths<br />

Age restricted 288<br />

No age<br />

restriction<br />

Difference<br />

453,000 deaths due to rotavirus infection globally<br />

(99 to 688)*<br />

605<br />

(310 to 1,133)*<br />

317<br />

additional<br />

vaccine associated IS<br />

deaths<br />

(211 to 445)<br />

Median (5 th and 95 th percentiles)<br />

Estimated<br />

rotavirus deaths<br />

averted<br />

156,100<br />

(110,100 to 201,800)<br />

199,200<br />

(140,700 to 255,400)<br />

43,100<br />

additional<br />

rotavirus<br />

deaths<br />

(30,600 to 53,500)<br />

Source: Patel M, Clark A et al 2012)

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