PDF catalog - Teknolab AS
PDF catalog - Teknolab AS
PDF catalog - Teknolab AS
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NON-POLAR SORBENTS<br />
ISOLUTE non-polar silica based sorbents provide hydrophobic interactions, from the highly retentive ISOLUTE<br />
C18 to the less retentive ISOLUTE C2. The non-polar sorbents can retain a range of compounds that vary in<br />
hydrophobic character. The sorbents are available in both non-endcapped and (in certain cases) endcapped<br />
versions to meet the needs of particular applications. Non-endcapped sorbents are particularly useful when<br />
utilizing secondary silanol interactions for extraction of basic drugs compounds (see pages 141-155<br />
[QuickStart Guide] for more information on utilizing secondary silanol interactions).<br />
ISOLUTE Silica-Based Non-Polar Sorbents<br />
Sorbent Description Structure Average<br />
Particle Size<br />
(µm)<br />
Pore<br />
Diameter<br />
(Å)<br />
C4 Butyl (non-endcapped) -Si-C 4 H 9 50 60<br />
C2 Ethyl (non-endcapped) -Si-C 2 H 5 50 60<br />
C2(EC)a Ethyl (endcapped) - 50 60<br />
CH(EC)a Cyclohexyl (endcapped) -Si- 50 60<br />
PH Phenyl (non-endcapped) -Si- 50 60<br />
PH(EC) a Phenyl (endcapped) - 50 60<br />
CN Cyanopropyl (non-endcapped) -Si-(CH 2 ) 3 CN 50 60<br />
CN(EC) a Cyanopropyl (endcapped) - 50 60<br />
a (EC) - endcapped, a chemical process to reduce the concentration of silica surface silanol groups that provide polar and<br />
weak cation exchange secondary interactions.<br />
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