Program Book - Confex

2:30 pm
723. Involvement of TLR7 and TLR9 in the Production of
Antiphospholipid Antibodies
Renan Aguilar-Valenzuela 1 , Kevin Nickerson 2 , Zurina Romay-
Penabad 1 , Mark J. Shlomchik 2 , Gracie Vargas 1 , Tuya Shilagard 1
and Silvia S. Pierangeli 1 , 1 University of Texas Medical Branch,
Galveston, TX, 2 Yale University School of Medicine, New Haven,
CT
2:45 pm
724. Endothelial Cell Injury and Activation Promote the Binding
of Anti-Phospholipid Antibodies and Thrombus Formation
Patrick Laplante 1 , Marc-Antoine Gillis 2 , Rebecca Subang 1 ,
David Salem 1 , Jerrold S. Levine 3 , Yahye Merhi2 and Joyce
Rauch 1 , 1 Research Institute of the McGill University Health
Centre, Montreal, QC, 2 Montreal Heart Institute, Montreal, QC,
3
University of Illinois at Chicago, Chicago, IL
3:00 pm
725. Mitochondrial Dysfunction in Monocytes From
Antiphospholipid Syndrome Patients: Implications in the
Pathogenesis of the Disease and Effects of Coenzyme Q
Treatment
Chary Lopez-Pedrera 1 , Carlos Perez-Sanchez 1 , Patricia Ruiz-
Limon 1 , Mª Angeles Aguirre 1 , Rosario Mª Carretero 1 , Nuria
Barbarroja 1 , Antonio Rodriguez-Ariza 1 , Eduardo Collantes-
Estevez 1 , Jose Antonio Gonzalez-Reyes 2 , Jose Manuel Villalba 2 ,
Francisco Velasco 1 , Munther A. Khamashta 3 , Maria Laura
Bertolaccini 3 and Mª Jose Cuadrado 4 , 1 IMIBIC-Reina Sofia
Hospital, Cordoba, Spain, 2 University of Cordoba, Cordoba,
Spain, 3 Lupus Research Unit, The Rayne Institute, Kings College
London School of Medicine, London, United Kingdom, 4 The
Rayne Institute, London, United Kingdom
3:15 pm
726. Effects of Fluvastatin on Pro-Inflammatory and Pro-
Thrombotic Markers in Antiphospholipid Antibody (aPL)-
Positive Patients: Preliminary Results from an Open-Label
Prospective Pilot Study
Vijaya L. Murthy 1 , Doruk Erkan 2 , Praveen Jajoria 1 , Rohan Willis 1 ,
JoAnn Vega 2 , Giuseppe Barilaro 1 , Gurjot Basra 1 , Elizabeth Hsu 1 ,
Laura Aline Martinez-Martinez 1 , Shraddha Jatwani 1 , Elizabeth
Papalardo 1 , Emilio B. Gonzalez 1 , Prashanth R. Sunkureddi 3
and Silvia S. Pierangeli 1 , 1 University of Texas Medical Branch,
Galveston, TX, 2 Barbara Volcker Center for Women and
Rheumatic Diseases, Hospital for Special Surgery, New York, NY,
3
The University of Texas Medical Branch, Nassau Bay, TX
3:30 pm
727. Rituximab in Antiphospholipid Syndrome (RITAPS) – A
Pilot Open-Label Phase II Prospective Trial for Non-Criteria
Manifestations of Antiphospholipid Antibodies (aPL)
Doruk Erkan 1 , JoAnn Vega 2 , Glendalee Ramon 2 , Elizabeth Kozora 3
and Michael D. Lockshin 2 , 1 Barbara Volcker Center for Women
and Rheumatic Diseases, Hospital for Special Surgery, New York,
NY, 2 Barbara Volcker Center for Women and Rheumatic Diseases:
Hospital for Special Surgery, New York, NY, 3 National Jewish
Health, Denver, CO
3:45 pm
728. European Registry of Babies Born to Mothers with
Antiphospholipid Syndrome
Arsene Mekinian 1 , Priscille loire-Berson 2 , Eric Lachassinne 3 ,
Pascale nicaise-Roland 4 , Eric Vicaut 5 , Jerome Stirnemann 6 ,
Sylvie chollet-Martin 4 , Mario Motta 7 , Angela Tincani 8 , Christine
Boinot 9 , Olivier Pourrat 10 , Tadej Avcin 11 , Rapr Tomsik 12 , Amelie
Benbara 2 , Sarah de Carolis 13 , Patricia Rovere 14 , Lionel Carbillon 2 ,
marie-Helene Aurousseau 15 , marie-Claire Boffa 16 and Olivier
Fain 6 , 1 Jean Verdier Hospital, Bondy, France, 2 Service de
gynécologie-obstétrique, Université Paris 13 , AP-HP, Hôpital
Jean Verdier, 93140, Bondy, France., Bondy, France, 3 Service
de néonatologie et pédiatrie, Université Paris 13 , AP-HP,
Hôpital Jean Verdier, 93140, Bondy, France., Bondy, France,
4
Unité Fonctionnelles d’Immunologie « Autoimmunité et
Hypersensibilités », AP-HP, Hôpital Bichat-Claude Bernard, Paris,
Paris, France, 5 Paris, France, 6 Service de médecine interne,
Université Paris 13 , AP-HP, Hôpital Jean Verdier, 93140, Bondy,
France., Bondy, France, 7 Obstetric and Gynecology of Brescia,
Brescia, Italy, 8 Rheumathology Unit, University of Brescia,
Brescia, Italy, Brescia, Italy, 9 Hemostase Poitiers, Poitiers,
France, 10 CHU poitiers, Poitiers, France, 11 University Children’s
Hospital Ljubljana, Ljubljana, Slovenia, 12 University Children’s
Hospital Ljubljana, Slovenie, Slovenia, 13 Rheumatology, Brescia,
Italy, 14 Rheumatology, Milan, Italy, 15 Bondy, France, 16 Service
d’hématologie biologique, Université Paris 13 , AP-HP, Hôpital Jean
Verdier, 93140, Bondy, France., Bondy, France
W193a
Cell-cell Interactions and Adhesion
Moderators: Bruce N. Cronstein, MD; New York University
Medical Center; New York, NY
Zoltan Szekanecz, MD, PhD; University of Debrecen Medical and
Health Sciences Center; Debrecen, Hungary
2:30 pm
729. IL-7 Contributes to Monocyte Migration In Rheumatoid
Arthritis
Nathan D. Chamberlain 1 , Sarah R. Pickens 1 , Richard M. Pope 2 ,
Michael Volin3 and Shiva Shahrara 1 , 1 University of Illinois at
Chicago, Chicago, IL, 2 Northwestern Univ Med School, Chicago,
IL, 3 Chicago College of Osteopathic Medicine Midwestern
University, Downers Grove, IL
2:45 pm
730. CCL21 a Novel Proangiogenic Factor in Rheumatoid
Arthritis
Sarah R. Pickens 1 , Nathan D. Chamberlain 1 , Michael Volin 2 ,
Arthur M. Mandelin II 3 and Shiva Shahrara 1 , 1 University of Illinois
at Chicago, Chicago, IL, 2 Chicago College of Osteopathic Medicine
Midwestern University, Downers Grove, IL, 3 Northwestern
University Feinberg School of Medicine, Chicago, IL
3:00 pm
731. Evidence for CXCL16 As An Endothelial Progenitor Cell
Chemotactic Factor
Jeffrey H. Ruth 1 , Takeo Isozaki 1 , M. Asif Amin 1 , Charles A. Lesch 1 ,
Ali S. Arbab 2 and Alisa E. Koch 3 , 1 University of Michigan, Ann
Arbor, MI, 2 Henry Ford Hospital, Detroit, MI, 3 Department of
Veteran’s Affairs and University of Michigan, Ann Arbor, MI
SUNDAY
November 6, 2011
2011 Program Book 35