Pre-Lab Preparation Sheet

Experiment 2: NSAIDS 2
Week 1
A. How can we isolate the drugs
Pre-lab Preparation Assignment:
1. Read:
-This Experiment handout
and
-Classification of unknown compounds from their solubilities in aqueous media: CHEM
211 Lab Manual p. A1.
-Extraction (Lab Manual Part V. A pp. A1-A2 and Padías: pp. 116-127)
-Stereoisomers: Lab Manual Part V A: sec. A->D. 3. (pp. B1-B6).
-Prepare for Exploration questions on pp. B2-B6.
2. Complete the Prelab activity on the course website by 5:00 PM Sunday, February 1.
3. In your lab notebook: (See Lab Manual pp. 14-16 for format.)
a. Set up the Table of Contents
b. Enter the title of this experiment
4. Bring your notebook to the Monday Lab Discussion period.
5. After the lab discussion, enter the Waste Disposal instructions for this experiment into your
notebook in the appropriate place.
Question of the Week:
How can we isolate propanoic acid NSAIDS from their tablets
In order to produce tablets that are easily consumed and can survive the shipping and handling
necessary to get them to drug stores, active ingredients, in this case the NSAID molecules, are
mixed with binding materials. Binding materials are largely made up of starch, a mixture of
large neutral (neither acidic nor basic) molecules.
After completing the pre-lab assignment, come to the Monday, lab discussion period with
suggestions as to how to answer the Question of the Week. You will be working with the same
lab group as youi did on Experiment 1.
Key Terms/concepts/techniques:
• Acid-Base Reactions
• Extractions
• Configurational Isomers
• Enantiomers
• Diastereomers
•
•
Epimers
Meso compounds
Safety Matters:
• Safety glasses are required.
• No sandals or open-toe shoes