IgE-Mediated Adverse Reactions to Vaccines Workshop ... - AInotes

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Why are there no serious reactions being reported • 3/4 manufacturers of injectable trivalent influenza vaccine (TIV) report the maximum amount of ovalbumin in the package insert and the other will provide the information on request. • The claimed amounts are all < 1 mcg per 0.5 mL dose. • The measured amounts in independent labora<strong>to</strong>ries are usually much lower than the claimed amounts.
What about LAIV • Although the intranasally-administered live attenuated influenza vaccine (LAIV) contains a low amount of ovalbumin, all published studies <strong>to</strong> date have evaluated the injectable trivalent inactivated vaccine (TIV), and thus TIV rather than LAIV should be used for egg-allergic recipients.
Page 1 and 2: IgE-Mediated Adverse Reactions to V
Page 3 and 4: Objectives •Develop a diagnostic
Page 5 and 6: Summary Statement 5. All suspected
Page 7 and 8: Summary Statement 6. IgE-mediated r
Page 9: • Persons who react to gelatin on
Page 12 and 13: Influenza vaccine contains measurab
Page 16 and 17: What about cell culture derived TIV
Page 18: What about cell culture derived TIV
Page 21 and 22: Yellow Fever Vaccine • A history
Page 23 and 24: • Yeast allergy itself is very ra
Page 25 and 26: • Latex content of vaccine packag
Page 28 and 29: Summary Statement 7. Patients who h
Page 30 and 31: • If the suspect vaccine contains
Page 32 and 33: • No formal studies to evaluate t
Page 34 and 35: • If vaccine or vaccine component
Page 36: Summary • Patients with suspected

IgE-Mediated Adverse Reactions to Vaccines Workshop ... - AInotes

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