RNA FOLDING DURING TRANSCRIPTION

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RNA FOLDING DURING TRANSCRIPTION

In case of the hairpin ribozyme, complementary

insertions of an interfering stem-loop upstream of

the ribozyme inhibited folding pattern more severely

than did an insertion downstream of the ribozyme.

In the case of the delta ribozyme, folding during

transcription was inhibited strongly by the presence

of a downstream portion of the viroid RNA. Folding of

the delta ribozyme was more efficient upon

decreasing the transcription speed.

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