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21st Century Program

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Chairperson: Imaharu Nakano<br />

15:15 – 15:45<br />

Host immunity to AAV vectors: impact on gene therapy<br />

Glenn Pierce, Ph.D., M.D.<br />

Consultant, Gene Therapy Clinical Development<br />

Formerly Vice President, Research and Clinical Development, Avigen, Inc., Alameda, U.S.A.<br />

15:45 – 16:00<br />

AAV and Regenerative Medicine<br />

Chairperson: Eiji Kobayashi<br />

16:00 – 16:20<br />

Muscle dedifferentiation and regeneration induced by AAV vector-mediated gene transfer<br />

Takeshi Endo, Ph.D.<br />

Department of Biology, Faculty of Science<br />

Chiba University, Chiba, Japan<br />

Chairperson: Hiroaki Okamoto<br />

16:20 – 16:40<br />

Characterization of an insulator in AAVS1<br />

Takamasa Takeuchi, Ph.D., M.D. and Tadahito Kanda, Ph.D.<br />

Division of Molecular Genetics<br />

National Institute of Infectious Diseases, Tokyo, Japan<br />

16:40 – 17:00<br />

Site-specific integration of a therapeutic gene into mesenchymal stem cells<br />

Masashi Urabe, M.D., Ph.D.<br />

Division of Genetic Therapeutics, Center for Molecular Medicine<br />

Jichi Medical School, Tochigi, Japan<br />

Chairperson: Yutaka Hanazono<br />

17:00 – 17:30<br />

Targeted gene delivery to embryonic stem cells<br />

R. Michael Linden, Ph.D.<br />

Department of Gene and Cell Medicine<br />

Department of Microbiology<br />

Mount Sinai School of Medicine, New York, U.S.A.<br />

Chairperson: Keiya Ozawa<br />

17:30 – 18:00<br />

Targeted and random integration of AAV vectors<br />

David W. Russell, M.D., Ph.D.<br />

Department of Medicine<br />

University of Washington, Seattle, U.S.A.<br />

Closing Remark<br />

18:00 – 18:10<br />

Shin-ichi Tominaga, M.D., Ph.D.<br />

Vice-Dean of Jichi Medical School, Tochigi, Japan<br />

18:15 ~19:30 Buffet-style dinner party at the SEIYODO restaurant <br />

Secretariat<br />

Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical School<br />

3311-1 Yakushiji, Minamikawachi-machi, Kawachi-gun, Tochigi 329-0498, Japan<br />

TEL: +81-285-58-7402 FAX: +81-285-44-8675 E-mail: dgtcmm@jichi.ac.jp

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