SCIENTIFIC CURRICULUM - Leitat

SCIENTIFIC CURRICULUM
March 2012
Research Areas
research@leitat.org
Research Coordinators:
Dr. Eng. Laurent Aubouy: laubouy@leitat.org
Meritxell De la Varga: mdelavarga@leitat.org
YOUR TECHNOLOGICAL PARTNER
LEITAT – Technological Center
Phone. +34 93 788 23 00
Fax. +34 93 789 19 06
www.leitat.org

LEITAT Technological Center
VOCATION
We offer high added value solutions to technological challenges required by companies, with a clear guidance
and vocational adaptation to the constant market changes.
FUTURE VISION
We support sustainable growth through the promotion of R+D+I and technology transfer, in the context of
creating lasting value for companies, satisfying the changing demands of global market.
RESEARCH UNITS
From a traditional structure to a flexible and dynamic organization, LEITAT seeks to ensure a rapid and
effective response by reducing levels of decision-making and bureaucracy. Prioritizing teams work and
projects with a horizontal communication and a definition of responsibilities in order to achieve meet the
expectations of the client and society.
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INDEX
Page
INDUSTRIAL BIOTECHNOLOGY 4
BIOINVITRO 7
BIOMED 10
NANOHEALTH & SAFETY 13
ANALYTICAL CHEMISTRY 16
FAST MOVING CONSUMER GOODS 19
NANOMATERIALS 22
ADVANCED POLYMERS 25
SURFACE TREATMENTS 28
TEXTILE TECHNOLOGIES 31
SMART SYSTEMS 34
NEW PRODUCTION PROCESSES 37
ENVIRONMENT 40
RENEWABLE ENERGIES 43
LEITAT TECHNOLOGICAL CENTER IS MEMBER OF 46
EUROPEAN TECHNOLOGY PLATFORMS 46
SPANISH TECHNOLOGY PLATFORMS 47
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INDUSTRIAL BIOTECHNOLOGY
Competency Compendium
Dr. Anna SURRIBAS
Coordinator of Industrial Biotechnology Division
Email: asurribas@leitat.org
Equipments:
Bioreactors
Incubators
Equipment for protein/enzyme activity characterization (SDS-PAGE)
Microbiology laboratory
Microscopy facilities
Dispermat® CV3
Spray drier
Rulla
Quirsec
Pilot scale fat crystallizer
Pilot scale homogenizer
SPECIFIC RESEARCH INTERESTS
Bioprocess development:
- Design and application of bioprocesses in industrial environment: use of enzymes and
microorganisms: Several activities can be addressed from biocatalyst screening, modification and
bioprocess development. Several analytical technologies can be set up for process monitoring.
- Enzyme immobilization, recuperation and reutilization. Kinetic studies: Immobilization systems can be
selected from commercial sources or specially designed and synthesized for custom needs by micro
and nanotechnologies. Enzyme activity protocols can be set up to follow enzyme activity during
immobilization. Several separation technologies can be studied ranging from filtration, magnetic
separation, centrifugation…
- Substitution of organic conventional reactions by biocatalytic reactions: Given a chemical process,
several alternatives can be designed in order to include biotechnological routes for the synthesis of
certain intermediates or products. Activities can include the process strategy, biocatalyst selection and
process development. Product analysis and separation can be also addressed.
- Isolation, selection and characterization of microorganisms for different applications and
functionalities: Novel microorganism can be isolated by strategic sampling according to the desired
applications, for example contaminated soils for contaminant-degrading microorganisms. Screening
methods can be designed to select the best strains.
Environmental Biotechnology.
- Biotechnological wastewater treatment: Both enzymatic and microbial processes for the
environmental sector can be developed. Activities include the development of enzymatic processes
for wastewater treatment, isolation of new microbial consortia, anaerobic digestionetc..
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- By-product/waste valorisation: Biotechnological processes can be designed for the valorisation of
certain by products. Activities have been addressed for the recovery of by product fibres, protein
hydrolysates, feed, biopolymers….
- Microbial/Enzymatic fuel cells technology: MFC can be designed with preferred microorganisms or
novel electrode materials for electricity recovery.
Applied microbiology:
- Application of antimicrobial/antimite ingredients and validation of their activity: Antimicrobial products
can be applied on different substrates (textiles, polymeric materials, membranes) and surfaces and
their antimicrobial behaviour can be assessed through international standards.
- Tailor made microbiological research: Tailor made microbiological research activities can be designed
to fulfil customer needs: study of biofilm formation, validation of higienization technologies, evaluation
of antimicrobial compounds and antimicrobial behaviour of products (detergents, cosmetics, food
conservants…)
Microencapsulation for several industrial sectors: textiles, food, cosmetics, etc.
Development of tailor-made microcapsules for applications in several industrial sectors. Activities
include: microcapsules development (using chemical technologies: Coacervation, gelation, interfacial
polymerization, sol-gel; spray-drying;); microcapsule characterization and release and stability studies.
Identification of valuable compounds from natural origin
Screening methodologies for identifying novel added-value compounds from natural resources into
biologically valuable compounds.
Development of improved fat based products
Downstream processing.
Several technologies and processes can be developed and applied for downstream applications:
membrane and tubular filtration, filter press, centrifugation… Filtration technologies are available at a
pilot scale. Purification methodologies can be developed according to custom needs.
Equipment for protein purification by FPLC is available.
MOST RELEVANT PROJECTS
1. ITACA: Research on Technologies of treatment, reuse and monitoring for future sustainability of water
treatment. INNPRONTA 2011, IPT-20111020
2. BioConSepT: Integration of Bio-Conversion and Separation Technology for the production and
application of platform chemicals from 2nd generation biomass. FP7-KBBE-2011-5. 289194
3. BioXplore: Novel methodology for the identification of valuable natural products derived from
Mediterranean Flora. ENPI
4. MICROSEGA: Biopolymeric microcapsules for food safety applications. VALOR 2010.
5. LIQUION: Research on ionic liquid technologies for industrial applications. Co-financed by CDTI. CEN-
2010-1011.
6. PHILYRA: “Microbiological characterization on textiles”. Henkel KGaA 2010-2011.
7. Research in Healthy Foods and Products.(INVIAS). CDTI project with Grup Lasem. IDI-20091068.
8. SEILA: New Technologies for an efficient, ecologic and intelligent washing system for the future textiles,
CENIT 2009. CEN20091005.
9. INSEPLATEX: Development of plastics and textiles with insect repellent and insecticide effect. LIA I+D+i
–CONSORCIADO, 2009 PID-600300-2009-12.
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10. FIBNATEX: Production and technical evaluation of natural fibres for the European south-western
industry. INTERREG SUDOE IV B, SOE1/P1/P188.
11. SAFEPROTEX: High protective clothing for complex emergency operations. FP7-NMP-2008-SME-2
project number 228439.
12. Fellowship on Enzyme Immobilization. Talent Empresa, 2009 TEM 00075.
13. Investigation of alternative technologies for industrial wastewater treatment. Ministry of Industry, Tourism
and Trade. 15/5/2008-31/12/09. DEX-560620-2008-82.
14. Technological transfer of new methodologies of enzymatic cotton processing in substitution of
conventional methods. PET2008_0222.
15. Immobilized enzymes for their use and re-use in textile processes. 2008ACOM00005.
16. Surface treatments to obtain antimicrobial materials IAP-560200-2008-2.
17. Modification of polyester surface using plasma and enzymatic technologies, IAP-560510-2008-3.
18. Design of bio-reactions with biocatalysts (enzymes) with application in industrial processes of the textile
sector, Icrea Junior Empresa 2006.
PUBLICATIONS AND ORAL COMMUNICATONS
1. A. Mª. Lozano, M. Arnautu, L. Bautista, M. de la Varga. "Textile with antimicrobial properties obtained by
polymerization of bifunctional quaternary ammonium derivatives. 21st IFATCC Congress 2008,
Conference, Full text paper in the Congress Proceedings, Barcelona (Spain), 7-9 May 2008.
2. M. de la Varga. “Industrial Biotechnology in textile sector”, INDUSTRIAL BIOTEC 2008, Oral
Communication, Brusseles (Bèlgica), 25-26 June 2008.
3. M. Garrido-Franco, “Combination of enzymatic methods for the (semi)continous processing of cotton",
BIOTEC 2008, Oral Communication, Granada, 17-19 September 2008.
4. M. de la Varga, M. Garrido-Franco, “Biotechnological solutions for conventional cotton treatments”,
EXPOQUIMIA 2008, Conference, Barcelona, 20-24 October 2008.
5. R.Paul, A.Surribas, M. Brouta, M. Alaman and H. Esteve. 2009. Hemp: an ecologic textile alternative.
Revista Química Textil, 195:30-34.
6. Anna Surribas, Marta Alamán, Alexandre Martínez, Marta Garrido, J. M. Botet Meritxell De la Varga.
Methodologies for cotton pretreatment by enzymatic processes in substitution to conventional treatments.
Revista de Química e Industria Textil, 198:36-43
7. A.Surribas. “White Biotechnology”. Learning session at the Universitat Autònoma de Barcelona. Bellaterra
(Spain), 3 rd October 2011.
8. Anna Ribé , Marolda Brouta-Agnésa, Elena Genescà, Roshan Paul. PALF: Nuevas oportunidades para la
fibra de hoja de piña. Revista de Química e Industria Textil, 204: 52-57
9. Laia Crespo, Ana Serret, Llorenç Bautista, Helena Esteve, Meritxell de la Varga,
Anna Surribas, Roshan Paul. “Chitosan Microspheres for Antibacterial Finishes”. Full text paper in the
world textile conference (Autex 2011)
10. Anna Surribas, Elena Genescà, Aleix Conesa, Roshan Paul, Marolda Brouta-Agnésa and Meritxell de la
Varga.” Novel industrial applications of enzymatic conversions”. 9th Green Chemical Congress. Alcalà de
Henares. 15th September 2011.
11. E.Genescà “White biotechnology: applications and status of the industry” OCTUBREBIO 2011,
Technological Center of La Rioja, Logroño (Spain), 4th October 2011
12. I. Forns, M. Brouta, T. Copete. “Antimicrobial Fabrics” Workshop at Innovation Afternoons CICLE 2011,
LEITAT, Terrassa (Spain), 15th December 2011
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BIOINVITRO
Competency Compendium
Dr. María-Jesús ZURBANO
Coordinator of the BioInVitro Division
Email: mjzurbano@leitat.org
Main research fields: In vitro technologies, customized research for cosmetic development and claim support,
in vitro ADMETOX assays, development of ready-to-use cell-based kits for in vitro ADMETOX studies.
Equipments:
Laminar flow hoods
CO2 incubators
Equipment for cell isolation
Leica DM IRBE microscope, equipped with fluorescence module and Leica ACC88 digital camera
Leica DMI 4000B Microscope equipped with fluorescence modules and Leica DFC 300FX digital
camera
Scan^R, Olympus
Multiskan Ascent microplate spectrophotometer
Elisa reader, SLT Lab Instruments 340 ATTC
Fluoroskan Ascent FL fluorimeter
Fluorimeter, Molecular Devices Spectra MAX Gemini XS
Refrigerated centrifuges
Lightcycler PCR 1.5, Roche
Safire 2 microplate absorbance fluorescence and luminiscence reader
Vertical freezer -80 ºC
Spectrophotometer Shimadzu model UV-240
High Performance Liquid Chromatography – Triple Quadrupole Mass spectrometry: Waters 2795-
Quattro Micro
Ultra Performance Liquid Chromatography – Triple Quadrupole Mass spectrometry: Waters Acquity -
Xevo TQ-S
Ultra Performance Liquid Chromatography – Q-TOF Mass spectrometry: Waters Acquity - Synapt
QTOF
High Performance Liquid Chromatography – Q-TOF Mass spectrometry: Agilent 1100 – ABSciex
QSTAR Elite
High Performance Liquid Chromatography – UV / FLD: Waters 2795
Full access to the Science Park of Barcelona (PCB) scientific and technical platforms, and to the University of
Barcelona (UB) scientific and technical services, comprising: 1) PCB: Automated Crystallography Platform,
Animal Research Centre, Combinatorial Chemistry Unit, Drug Discovery Platform, Nanotechnology Platform,
Polymorphism and Calorimetry Platform, Proteomics Platform, Transcriptomics Platform, Unit of Experimental
Toxicology and Ecotoxicology, 2) UB: Quality Assurance Unit, Genomics Unit, Magnetic nuclear resonance
Unit, Transcriptomics Unit, Proteomics Unit, Fine chemistry Unit, Peptide synthesis Unit, Nanometric
Techniques Unit, Cytometry Unit, Confocal microscopy and cellular micromanipulation Unit, Electron
microscopy and in situ molecular identification Unit, Separative tecnhiques Unit.
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SPECIFIC RESEARCH INTERESTS
Skin biology/care.
The expertise of BioInVitro Division members rely on more than 10 years of experience in cell culture,
molecular biology, toxicity and efficacy studies. Assays and models can cover both safety and efficacy testing
of raw materials or final products. We can also provide customized research and scientific consulting to
cosmetic industry.
Our in vitro systems are of special value to support marketing claims to provide insights into cell molecular
mechanisms. These systems are useful at early stages of product development, as an alternative to animals,
and prior to in vivo assessment in human volunteers. Some of our assays include anti-aging, vitalizing,
firmness, anti-oxidant effect, elasticity, anti-inflammatory effect, moisturizing, skin repair, photoprotection,
reconstruction, calming effect, use of reconstructed 3D human tissues, irritation and corrosion testing, acute
toxicity, citotoxicity, phototoxicity, genotoxicity, teratogenicity and skin sensitization.
Studies are conducted following Good Laboratory Practices, as well as, OECD and ECVAM test procedures.
ADME and toxicity.
Our team can help you in your in vitro Absorption, Distribution, Metabolism and Toxicity assays following
rigorous quality standards under FDA guidelines and GLP standards.
We conduct in vitro models based on cells. In vitro approaches are often extremely
cost-effective in comparison with in vivo studies. In vitro studies allow a lot of information to be generated
within a short time and at an acceptable cost during early stages of development, as well as evaluation of new
molecules and active ingredients. We provide our customer problem solving in drug metabolism to support
their drug discovery and development processes using, different in vitro systems, including microsomes,
systems expressing individual CYPs (recombinant microsomes and engineered cell lines) and freshly isolated
hepatocytes from different species.
Additionally, we offer bio-analytical support through method development and validation, in vitro
bioequivalence, metabonomics and proteomics.
Absorption: Intestinal barrier, skin barrier, renal barrier, blood brain barrier, transport studies (FDA
Guidance and EMEA Guidelines), drug delivery and Biopharmaceutical Classification System.
Distribution: Partition coefficient and Protein Binding (plasma/serum).
Metabolism: Drug metabolism stability, drug clearance, drug-drug interaction (drug inhibition and induction
studies on CYP450 and UGT enzymes), phenotyping of Phase I enzymes (CYP P450 enzyme mapping),
quantification of Phase II metabolizing enzymes (UGT1A1, UGT1A6, UGT1A9 and UGT2B7), protein
binding, adduct formation, interspecies metabolic comparison, metabolite identification and structural Q-
TOF analysis, multivariate analysis for biomarker selection (PLSDA, PCA), pattern recognition in
metabolomic studies (PLSDA, PCA), skin metabolism.
Toxicity: Classical cell-viability assays (MTT, WST-1, NRU, LDH), acute toxicity, genotoxicity,
phototoxicity, photogenotoxicity, mitochondrial toxicity (ATP balance, mitochondrial membrane potential,
oxidative stress), metabolic alterations (albumin synthesis, ureogenesis, carbohydrate metabolism,
intracellular calcium levels) and hepatotoxicity (general hepatotoxicity, esteatosis, toxicity mechanism
identification, multiparametric assay)
MOST RELEVANT PROJECTS
1. NANOTEST: Alternative Testing Strategies for the Assesment of the toxicological profile of nanoparticles
used in medical diagnosis. FP7. HEALTH-2007-1.3-4.
2. CARCINOGENOMICS: Development of in vitro test methods for identification of carcinogenic substances.
FP6. LIFESCIHEALTH LSH-2005-1.2.3-1.
3. ACUTETOX: Developing an in vitro test strategy sufficiently robust and powerful to completely replace in
vivo testing of acute toxicity of chemicals. FP6. LIFESCIHEALTH LSH-2003-1.2.3-1.
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4. LINTOP: Optimization of liver and intestine in vitro models for pharmacokinetic and pharmacodynamic
studies. FP6. LIFESCIHEALTH LSH-2005-1.2.3-4.
PUBLICATIONS
1. Quintás G et al. Chemometric approaches to improve PLSDA model outcome for predicting human nonalcoholic
fatty liver disease using UPLC-MS as metabolic profiling tool. Metabolomics 2011 (in press).
2. Kuligowski J et al. Direct determination of polymerized triacylglycerides in deep-frying vegetable oil by
near infrared spectroscopy using Partial Least Squares regression. Food Chemistry 2011 (in press).
3. Schroeder K et al.. Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA
industry sectors. Toxicol In Vitro. 25:589-604, 2011.
4. Vila MR et al. A new ready-to-use concept for in vitro evaluation of biotransformation-mediated toxicity
(Abstract). Toxicology Letters, 2010, 196S, S37-S351.
5. Gombau L et al. Assessment of the inhibition on major human CYP450 isoforms as a predictor of
putative interaction on concomitantly administered drugs for a new compound under development. An
activity of the Melius project (Abstract). Toxicology Letters 2010, 196S, S37-S351.
6. Quintás G et al. Metabolic characterization of PB60 and PB65, two peptidomimetics which notably
facilitate the transport of heparin across the intestinal barrier. An activity of the Melius project (Abstract).
Toxicology Letters 2010, 196S, S37-S351
7. Gómez-Lechón MJ et al. In vitro evaluation of potential hepatotoxicity induced by drugs. Curr Pharm Des.
2010;16(17):1963-77
8. Kuligowski J et al. Sample classification for improved performance of PLS models applied to the quality
control of deep-frying oils of different botanic origins analyzed using ATR-FTIR spectroscopy. Anal
Bioanal Chem. 2011 Jan;399(3):1305-14
9. Dusinska M et al. Testing strategies for the safety of nanoparticles used in medical application.
Nanomedicine. 2009 Aug; 4(6):605-7.
10. Quintás G et al. Use of Fourier transform infrared spectrometry for the on-line study of focusing
mechanism in capillary electrophoresis. Analytical and Bioanalytical Chemistry 2007, 387, 287-292.
11. Lahoz A et al. In Vitro ADME Medium/High-Throughput screening in drug preclinical development. Mini-
Reviews in Medicinal Chemisry 6:1053-62, 2006.
12. Gombau L et al. Polypodium leucotomos extract: antioxidant activity and disposition. Toxicol In Vitro
20:464-71, 2006
13. Lahoz A and Gombau L Alteraciones en la función celular por la acción de fármacos. Las ómicas:
Genómica, Proteómica, Citómica y Metabolómica. Nuevas tecnologías para el desarrollo de fármacos.
Chap 9. Detección de las alteraciones de la función celular en el desarrollo de nuevos fármacos. Pag
229-266, 2005
14. Serradell M et al. Uremic medium causes expression, redistribution and shedding of adhesion molecules
in cultured endothelial cells. Haematologica. 2002 Oct;87:1053-61.
15. Serradell M et al. Uremic media affects hemostatic properties of human endothelial cells in cultureand
increases the production of von Willebrand factor. Nefrologia. 2002;22:33-41.
16. Sitges M et al. Acute and mid-term combined hormone replacement therapy improves endothelial
function in post-menopausal women with angina and angiographically normal coronary arteries. Eur
Heart J. 2001 Nov;22 (22):2116-24.
17. Gálvez A et al. Desmopressin (DDAVP) enhances platelet adhesion to the extracellular matrix ofcultured
human endothelial cells through increased expression of tissue factor. Thromb Haemost. 1997 May; 77
(5):975-80.
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BIOMED
Competency Compendium
Dr. Francesc MITJANS
Coordinator of the Biomed Division
Email: fmitjans@leitat.org
Main research fields: Cancer therapy; diagnosis, prognosis & monitoring of diseases; specialized bioservices
including monoclonal antibody generation and functional activity profiling of potential drugs,
compounds and extracts.
Equipments:
Laminar flow hoods, CO2 incubators, Roller cell culture system, Leica DMIL microscopes, one equipped
with fluorescence modules and Leica DF420C digital camera, Multiskan Ascent microplate
spectrophotometer, Leica RM2255 fully motorized rotary microtome & Histobath, Fluoroskan Ascent FL
fluorimeter, Refrigerated centrifuges, PCR Stratagene equipment, Robotized liquid handling workstation
modules, AutoMACSpro, AKTA purifier system
Full access to the Science Park of Barcelona (PCB) scientific and technical platforms, and to the University
of Barcelona (UB) scientific and technical services, comprising:
PCB: Automated Crystallography Platform, Animal Research Centre, Combinatorial Chemistry Unit, Drug
Discovery Platform, Nanotechnology Platform, Polymorphism and Calorimetry Platform, Proteomics
Platform, Transcriptomics Platform, Unit of Experimental Toxicology and Ecotoxicology.
UB: Quality Assurance Unit, Genomics Unit, Magnetic nuclear resonance Unit, Transcriptomics Unit,
Proteomics Unit, Fine chemistry Unit, Peptide synthesis Unit, Nanometric Techniques Unit, Cytometry Unit,
Confocal microscopy and cellular micromanipulation Unit, Electron microscopy and in situ molecular
identification Unit, Separative tecnhiques Unit.
SPECIFIC RESEARCH INTERESTS
Oncology / Therapy
The expertise of Biomed Division members rely on more than 15 years of experience in basic and applied
oncologic research in the pharmaceutical industry arena. Some of the targets and drug candidates previously
developed by our scientists are currently in phase III, II, and I oncologic clinical trials.
Actually, our therapeutic focus is cancer in its broad sense and therefore represented by any of the three
compartments: tumour (tumoural cells), vascular (activated endothelial cells), stromal (support cells), and also
including cancer stem cells and metastatic dissemination. Recent R&D activities also include inflammation
and autoimmune diseases
The principal investigation activity of the team involves the identification of new oncology therapeutic targets,
the validation of these targets, the generation of therapeutic agents (specially monoclonal antibodies, Mabs),
the study of its mechanisms of action, and the functional characterization of these agents (monoclonals and
chemical compounds) in validated in vitro & in vivo models of both tumor progression and tumor
angiogenesis. Final aim is to deliver these innovative drugs as clinical development candidates (preclinical
proof of principle - PoP).
Diagnosis
An additional goal includes the design and characterization of front-edge reagents, tools and devices
(biosensors) for diagnosis, prognosis and monitoring of cancer and other diseases.
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Biomed Division goal is to position itself as a reference center in theragnosis.
Specialized bio-services
We provide consultancy and assessment services in drug discovery programs.
Based on our oncologic profiling resources we are able to provide the basis to identify unrevealed indications
for known leads. We perform reprofiling/repositioning research for oncologic, inflammatory and autoimmune
disorders.
Additional R&D tailored research for customers and collaborations include the next technological platforms:
In vitro cell models (oncology, immunology, inflammation: proliferation, viability, apoptosis, nanotox,
migration, adhesion, angiogenesis, Cancer stem cells, ADCC, cytokine release, etc)
In vivo animal models (oncology: singenic & xenogenic, subcutaneous & orthotopic primary tumor
with cell lines and clinic explants, experimental & spontaneous metastasis, angiogenesis, noninvasive
imaging; acute and chronic inflammation & pain)
Preclinical histology (paraffin embedding, sectioning and standard staining)
Generation of monoclonal and polyclonal antibodies for basic research, diagnosis and therapy.
Monoclonal antibody engineering: chimeric, humanized and biosimilars
MOST RELEVANT PROJECTS
1. VACMON: biosensor for fast vaccine monitoring. PID-560200-2009-2.
2. NANOTHER: Integration of novel NANOparticle based technology for THERapeutics and diagnosis of
different types of cancer, NMP-2007
3. NOBITAN: Novel biofocused targeting of nucleoside analogues with cyclic RGD peptides as enhanced
anticancer therapy, Eurotransbio-2011
4. LIFE: Comprehensive challenge to breast cancer. Cenit project - 2011
5. DENDRIA: “Soluciones innovadoras para acelerar la identificación y desarrollo de fármacos en
patologías del Sistema Nervioso” CENIT Project. 2010.
6. MIND: Multidisciplinary Investigation of Neurodegenerative Diseases. CENIT project. CEN 20081013.
7. ONCOLOGICA: New Strategies based on biomarkers for cancer detection, prognosis, response
prediction and the development of new treatments. CENIT project. CEN 20091016.
8. NANOMOLECULAR: Contrast agent with pharmacokinetics close to clinical needs and the ability to
increase the resolution of a dual-energy digital mammography. NUCLI/ACC10 project. 2010
9. PETPRO: Development of anti-angiogenic peptides using Zera technology. NUCLI/ACC10 project with
Era Biotech. RD09-1-0036
10. ROBIOCAT: Robotized nanobiocharacterization station . VALTEC/ACC10 project with the Electronics
Department of the UB. VALTEC09-2-0058
11. Biomed Division as emergent group. AGAUR project. SGR 2009.
12. Characterization of predictive genetic models of response to anticancer drugs: systematic personalized
therapeutic intervention. CDTI project with Pangaea Biotech.
13. Formulation of docetaxel nanoparticles. CDTI project with GP Pharm..
14. ROBOCELL: Robotic Station for biocaracterizacion: system optimization and development of tools and
sensors to measure interaction forces in specific biomedical applications. TEC2009-10114, with the
Electronics Department of the UB.
15. NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and
recycling of polymer nanocomposites used in various industrial applications, NMP-2009-1.3-1
16. GENIUS: Desarrollo, consolidación y explotación de plataformas tecnológicas en el proceso de
descubrimiento de medicamentos innovadores. CENIT project. CEN 20061005
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PUBLICATIONS
1. Acero N, Braña MF, Añorbe L, Domínguez G, Muñoz-Mingarro D, Mitjans F, Piulats J. Synthesis and
biological evaluation of novel indolocarbazoles with anti-angiogenic activity. Eur J Med Chem. 2012;
48:108-13.
2. Marchán S, Pérez-Torras S, Vidal A, Adan J, Mitjans F, Carbó N, Mazo A. Dual effects of β3 integrin
subunit expression on human pancreatic cancer models. Anal Cell Pathol (Amst). 2010 Oct 26.
3. Cupido T, Spengler J, Ruiz-Rodriguez J, Adan J, Mitjans F, Piulats J, Albericio F. Amide-to-ester
substitution allows fine-tuning of the cyclopeptide conformational ensemble. Angew Chem Int Ed Engl.
2010 Apr 1;49(15):2732-7
4. Mencía N, Selga E, Rico I, de Almagro MC, Villalobos X, Ramirez S, Adan J, Hernández JL, Noé V,
Ciudad CJ. Overexpression of S100A4 in human cancer cell lines resistant to methotrexate. BMC
Cancer. 2010 Jun 1;10:250
5. Vizán, P., S. Sánchez-Tena, G. Alcarraz-Vizán, M. Soler, R. Messeguer, M.D. Pujol, W-N. Paul Lee, M.
Cascante. Characterization of the metabolic changes underlying growth factor angiogenic activation:
identification of new potential therapeutic targets. Carcinogenesis. 2009; 30(6):946-52.
6. Roca, R.Messeguer R. Genómica (2009). In: Biotechnology and Drugs. Ed. Consejo General de
Colegios Oficiales de Farmacéuticos. p.p. 17-43.
7. Masa M. Genómica (2009). In: Biotechnology and Drugs. Ed. Consejo General de Colegios Oficiales de
Farmacéuticos. p.p. 117-142.
8. Piulats J, Mitjans F. “Angiogenic switch pathways" in Principles of Molecular Oncology, 2007 (3d Edition),
p.p. 411-441. Eds: Miguel H Bronchud, MaryAnn Foote. Springer Press. New York.
9. F. Mitjans, J. Piulats. Clinical implications of basic research. Angiogenesis: target new cancer treatments.
Gastroenterología y Hepatología Continuada. 2007. 6(1): 27-31.
10. Bosch B, Clotet-Codina I, Blanco J, Pauls E, Coma G, Cedeno S, Mitjans F, Llano A, Bofill M, Clotet B,
Piulats J, Este JA. Inhibition of human immunodeficiency virus type 1 infection in macrophages by an
alpha-v integrin blocking antibody. Antiviral Res. 2006 March; 69(3):173-80.
11. Fernandez Y, Queralt J, PAvía X, Piera C, Ramírez de Arellano I, Mitjans F, Messeguer R, Piulats J,
Carrió I. Multitracer in vivo assessment of tumor models with 18F-fluorothymidine, 18FFDG and N-
ammonia PET in mice. Eur J Nucl Med Mol Imaging 2006, 33 (supl II): S249.
12. Enns A, Korb T, Schluter K, Gassmann P, Spiegel HU, Senninger N, Mitjans F, Haier J. Alphavbeta5-
integrins mediate early steps of metastasis formation. Eur J Cancer. 2005 May; 41(7):1065-72.
PATENTS
1. Ciudad C, Noé V, Hernández JL, Masa M, New disrupting therapeutic technology. PCT/EP2011/055647.
Leitat Technological Center.
2. Hernández JL, Adan J, Martínez JM, Masa M, Messeguer R, Mitjans F, Dakhel S, Coll A, Hervas R,
Padilla L. Antibodies for therapeutic use, target “a”. EP11382010.4. Leitat Technological Center.
3. Hernández JL, Adan J, Martínez JM, Masa M, Messeguer R, Mitjans F, Coll A, Hervas R, Calvis C,
Dakhel S. “S100A4 Antibodies and Therapeutic Uses Thereof”. PCT/EP2011/059868 . Leitat
Technological Center.
4. Mitjans F, Adan J, Calvis C, Lavilla R, Miguel M, Albericio F, Ruiz J. Péptidos cíclicos rgd de aminoácidos
basados en tiazoles u Oxazoles como antagonistas selectivos de la integrina αvβ3. WO 2012/062777
A1. Leitat Technological Center.
5. Goodman S, Hahn D, Mitjans F, Adan J, Lo K-M. Engineered anti-alpha v-integrin hyibrid antibodies.
International Patent nº WO 2009/010290 A2. Merck KGaA.
Goodman S, Wilm C, Mitjans F. “Antibodies for the Detection of Integrin Complexes in FFPE Material”.
WO2011020529. Merck KGaA.
12

NANOHEALTH & SAFETY
Competency Compendium
Dr. Socorro VÁZQUEZ-CAMPOS
Coordinator of NanoHealth & Safety Division
Email: svazquez@leitat.org
Equipments:
Zeta Potential (Determination of stability of colloidal dispersions)
DLS (Determination of size distribution of colloids in solution)
BET (Determination of the surface area and the porosity of nanoparticles)
UV-Vis (Optical properties of nanoparticles and particle surface functionalization evaluation)
FT-IR (Characterization for the functionalization of nanomaterials)
TGA (Determination of surface functionalization of nanomaterials)
DSC (Analysis of physicochemical changes as degradation, oxidation, crystallinity or melting in
nanofilled matrices)
ICP-MS (Quantification and detection of metallic nanoparticles)
Ultrasonic horn (Dispersion of nanoparticle solutions)
Electrospinning (Synthesis of polymeric and ceramic nanofibers and nanocapsules)
Aging chambers (Determination of migration, release or transformation of the nanofillers exposed to
defined environmental conditions)
Other techniques used in external facilities (TEM, SEM, XPS, XRD, CLSM, …)
Facilities and equipment for in vitro and in vivo toxicological studies
Characterization techniques to determine the physical and mechanical properties of nanocomposites
RESEARCH ACTIVITIES
Nanotoxicology (in vitro and in vivo toxicity evaluation of nanomaterials, mechanistic studies, cell
internalization studies)
Evaluation of physical-chemical properties of nanomaterials included in industrial products during
their life cycle (from synthesis, processing, manufacturing, use, recycling, to final disposal)
Accelerated aging/ weathering of products containing NM (simulation of nanomaterials/
nanocomposites use)
Determination of the release of NM from complex matrices during simulating aging processes
Correlation analysis of the physical-chemical properties of nanomaterials and their toxicity
Design and development of novel filtration techniques for nanomaterials based on nanofiberbased
filters
Design and development of novel recycling and disposal techniques for nanomaterials based on
nanofiber-based filtration
RA/LCA analysis of nanomaterials included in commercial products
Design and development of worker protective equipment for workers manipulating nanomaterial
Design and development of nanobiosensors for several applications, such as, real-time vaccine
and food monitoring, disease diagnostics, explosive and gas detection…
Synthesis and functionalization of metallic nanoparticles for biological applications
Development of nanoparticle-based drug delivery systems
Design of nanoparticle-based markers to study biological processes
13

RESEARCH EXPERIENCE
Inorganic and organic nanoparticle synthesis, and characterization
Functionalization of nanoparticles through covalent and biodegradable linkages to organic molecules,
biomolecules, drugs...
Synthesis and characterization of smart polymeric nano and microparticles by radical polymerization to
obtain porous particles of different sizes using an heterogeneous polymerization (emulsion,
suspension and dispersion)
Encapsulation of the drug and studies about release of therapeutic agents
Multi-step synthesis, purification and characterization of organic compounds
Synthesis, purification and characterization of natural products with polyheterocyclic structure
Analytical Skills: HPLC purification, NMR spectroscopy, MALDI-TOF and ESI mass spectrometry, UV-
Vis spectroscopy, IR, bead sorting (COPAS TM technology), Edman degradation, SPR, peptide
synthesizer (Syro, MultiSynTech), Circular Dichroism, flow cytometry, SEM and SEM-FIB, CLSM,
TEM, AFM and STM, XPS, ζ-potential, DLS, particle size analyzer
Optimization of nanomaterial dispersion protocols and characterization of dispersions for use in
(eco)toxicological studies
In vitro and in vivo imaging and toxicological evaluation of nanomaterials. Cell culture,
micromanipulation and microinjection in reproductive cells, biokinetic and toxicological in vivo studies
Evaluation of nanomaterial cell internalization pathways
Cell and biomolecules characterization by means of microelectronic and microfluidic devices
MOST RELEVANT PROJECTS
1. EUROTAPES: European development of superconducting tapes: Integrating novel materials and
architectures into cost effective processes for power applications and magnets, NMP-2011-2.2-1; WP
leader: Life cycle assessment
2. NANOMICEX: Mitigation of risks and control of exposure in nanotechnology based inks and pigments,
NMP-2011-1.3-2; WP leader: Adapted streamlined life cycle/ risk assessment of nanoparticle-based inks
and pigments
3. SANOWORK: Safe nano worker exposure scenarios, NMP-2011-1.3-2; WP leader: Risk analysis
4. CERAMPOL: Ceramic and polymeric membranes for heavy metal and drug water purification, NMP-2011-
1.2-3, WP leader: Risk assessment of nanotechnology-based membranes during their whole life cycle
5. NEXTEC: Next generation nano-engineered thermoelectric converters. From concept to industrial
validation; NMP-2010-1.2-3; WP leader: Life cycle impact assessment
6. NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and
recycling of polymer nanocomposites used in various industrial applications, NMP-2009-1.3-1;
Coordinator
7. VACMON: Nanobiosensor for fast vaccine monitoring. PID-560200-2009-2; Coordinator
8. NANOSOST: Towards a sustainable, responsible and secure nanotechnology. Financed by the Ministry of
Industry, Tourism and Commerce. PSE-420000-2008-2; WP Leader: Nanotechnology-based materials for
barrier applications
9. ELECTROCLAY: Development and processing of conductive nanoclays to obtain multifunctional
conductive polymers. Financed by the Ministry of Industry, Tourism and Commerce (2008), IAP- 600200-
2008-49; Partner: Development of PANI-based nanoclays composites for conductive applications
PUBLICATIONS
1. J. Vila-Planas, E. Fernández-Rosas, B. Ibarlucea, S. Demming, C. Nogués, J. A. Plaza, C. Domínguez, S.
Büttgenbach, A. Llobera. “Cell analysis using a multiple internal reflection photonic lab-on-a-chip” Nature
Protocols 2011, 29;6(10):1642-55.
14

2. M. Faccini, D. Amantia, S. Vázquez-Campos, C. Vaquero, J. M. Lopez de Ipiña, L. Aubouy. “Nanofiberbased
filters as novel barrier systems for nanomaterial exposure scenarios” J. Phys.: Conf. Ser., 2011,
304, 012067.
3. S. Vázquez-Campos, E. Fernández-Rosas, M. Masa, F. Mitjans, L. Aubouy. Nanopolytox: Toxicological
impact of nanomaterials included in polymer nanocomposites along their life cycle. Proceedings of
Modern Polymeric Materials for environmental applications. 2011, 4(2), 247-254.
4. J. M. Amigo, N. G. Bastús, R. Hoen, S. Vázquez-Campos, M. Varón, M. Royo, V. Puntes. “Analysis of
time-dependent conjugation of gold nanoparticles with an antiparkinsonian by using curve resolution
methods” Anal. Chim. Act. 2010, doi:10.1016/j.aca.2010.10.014.
5. E. Fernandez-Rosas, R. Gómez, E. Ibañez, L. Barrios, M. Duch, J. Esteve, J. A. Plaza, C. Nogués.
”Internalization and cytotoxicity analysis of silicon-based microparticles in macrophages and embryos”
Biomedical Microdevices 2010, 12(3):371-379.
6. E. M. Campo, M. J. Lopez Martinez, E. Fernandez, L. Barrios, E. Ibañez, C. Nogués, J. Esteve, J. A.
Plaza. “Focus ion beam micromachined glass pipettes for cell microinjection” Biomedical Microdevices
2010, 12(2):311-316.
7. B. Ibarlucea, E. Fernandez-Rosas, J. Vila-Planas, S. Demming, C. Nogues, J. A. Plaza, S. Büttgenbach,
A. Llobera. “Cell screening using disposable photonic lab on a chip systems” Analytical Chemistry 2010,
82(10):4246-51.
8. W. Xu, M. Dong, H. Gersen, S. Vázquez-Campos, X. Bouju, E. Laegsgaard, I. Stensgaard, M. Crego-
Cálama, D. N. Reinhoudt, T. R. Linderoth, F. Besenbacher. “Exploring the transferability of large
supramolecular assemblies to the vacuum-solid interface” Nano Res. 2009, 2, 535-542.
9. M. J. Lopez Martinez, E. M. Campo, D. Caballero, E. Fernandez, A. Errachid, J. Esteve, J. A. Plaza.
“Versatile micropipette technology based on deep reactive ion etching and anodic bonding for biological
applications” J. Micromech. Microeng. 2009, 19 105013.
10. E. Fernandez-Rosas, R. Gómez, M. Duch, J. Esteve, E. Ibañez, L. Barrios, C. Nogués, J. A. Plaza.
“Intracellular Polysilicon Barcodes for Cell Tracking” Small 2009, 5(21):2433-2439.
Oral and Poster Presentations (2012-2011)
1. E. Fernández-Rosas, G. Janer, M. Busquets, V. Puntes, S. Vázquez-Campos. “MWCNT polymer
nanocomposites: Migration and/or release of nanoadditives in polymeric matrices during aging
processes” NanoImpactNet-QNano conference (Dublin), 27 February - 2 March 2012. Oral presentation.
2. E. Mas del Molino, G. Janer, E. Fernández-Rosas, R. Hernández, S. Vázquez-Campos. “In vitro toxicity
assessment of pristine and functionalized nanoparticles” Annual IVTS Meeting (Liverpool), 8 and 9th
November 2011. Oral Presentation.
3. G. Janer, E. Fernández-Rosas, R. Fernández, S. Vázquez-Campos. “In vitro toxicity assessment of
functionalized and aged nanoparticles”. 6 th International Conference on Environmental Effects of
Nanoparticles and Nanomaterials. London (United Kingdom), 19-21 September 2011. Poster
Presentation.
4. Socorro Vázquez-Campos. Nanosafety Cluster Meeting, Budapest (Hungary), 30 th May 2011. Oral
Presentation on “Outcomes of the Nanosafety Cluster meeting in Barcelona”
5. Socorro Vázquez-Campos. “Life Cycle Assessment of Nanomaterials in Polymer Nanocomposites:
Nanopolytox approach”. ENPRA Workshop: Challenges of regulation and risk assessment of
nanomaterials, Ispra (Italy), 10-12 May 2011. Oral Presentation.
6. Socorro Vázquez-Campos, María Blázquez. “Life Cycle Analysis of Nanomaterials: An overview”.
Imaginenano Conference. Bilbao (Spain), 11-14 April 2011. Oral Presentation.
7. Socorro Vázquez-Campos, María Blázquez. Nanosafety Cluster Meeting, Lausanne (Switzerland), 17 th
February 2011. Oral Presentation on “Review of WG3 activities on LCA”
15

ANALYTICAL CHEMISTRY
Competency Compendium
Aleix CONESA
Coordinator of Analytical Chemistry Division
Email: aconesa@leitat.org
Equipments:
ICP-MS – Agilent 7500
Gas chromatography
- GC-MS (with Headspace, Purge and trap, Thermal Desorption and SPME) – Varian Saturn
2100
- Micro CG (for Biogas analysis)- Varian 490-PRO
Liquid Chromatography
- HPLC-PDA - Varian ProStar
- HPLC – UV / FLD - Waters 2795
- UPLC-SQD – Waters ACQUITY
- HPLC – TQ: Waters 2795 Quattro Micro
- UPLC-TQ - Waters Acquity -Xevo TQ-S
- HPLC- Q-TOF - Agilent 1100 – ABSciex QSTAR Elite
- UPLC- Q-TOF - Waters Acquity - Synapt QTOF
- Size Exclusion Chromatography (GPC) – Agilent 1200, Varian 390-LC with Light Scatterig
and Refractive Index detectors
- Dionex ICS3000 (with conductivity and electrochemical detectors)
Total Organic Carbon (TOC) – Shimadzu V-C DCH
Nitrogen Kjeldahl – Buchi Kjelfelx K-360
UV-Vis (with Peltier) – Shimatzu UV2450
FTIR-ATR – Shimadzu Affinity
Elemental Analysis – EuroVector EA3000
Microwave – CEM Mars
Differential Scanning Calorimetry (DSC) – TA Instrument Q50
Thermogravimetry (TGA) – TA Instrument QS500
Karl Fisher – Metrohm KF 831
Automatic Titration Chemistry laboratory – Metrohm 809 Titrando and 814 USB
16

SPECIFIC RESEARCH INTERESTS
Analytical method development and validation.
Detection, quantification and valorization of high added value products from residues and feedstock:
Biorefinery, algae, etc.
Detection and quantification of nanoparticles.
Determination of different kind of pollutants in several matrices like water, soil and others.
Soil analysis.
Drug quantifications in blood and other biological fluids.
Waste characterization.
Metal detection and quantification by ICP-MS.
Chemical resistance of materials and barrier properties.
REACH Assessment.
Substitution of High Concern Substances: Green Chemistry.
Study and definition of exposure scenarios of chemicals.
Biodegradability assays (OECD official methods).
Chemical analyses for ECOLABEL certification.
MOST RELEVANT PROJECTS
1. BIOCONCEPT, Towards a sustainable bio-industry - Biotechnology for renewable chemicals and
innovative downstream processes, KBBE.2011.3.4-02
2. ITACA, Investigación de tecnologías de tratamiento, reutilización y control para la sostenibilidad futura de
la depuración de aguas, Innpronta.
3. BIOALGAL, Biological compounds obtained by microalgal innoative extraction processes, RDNET10-1-
0009.
4. PHYLIRA, Study of malodor after washing on wet textiles.
5. FERRARID, Sustainable and high performance aggregates for 21st century. Collaborative projects of
research and development destined to creat innovation nucleus, RDITCCON07-1-0003.
6. Development of informatics tools to support the evaluation of the chemical safety according REACH in
the manufacturing packaging processes. REACH PACK, national program Call of experimental
development- technological center subprograms. REA-09-AC001
7. Research on detection and control of toxic products in textile sector. Profit CT, Ministerio de Industria,
Turismo y Comercio. FIT G08360232/05.
8. ECOMETRE (Ecological Metal Recovery). European Project: CIP-EIP-Eco-Innovation-2008, 239037.
June 2009-November 2011.
9. Investigation of alternative technologies for industrial wastewater treatment. Nacional Project: Ministerio
de Industria, Turismo y Comercio; LIA CT 2008. Ref: DEX-560620-2008-82.
10. Treatment and waste valorization from a pharmaceutical company. Industrial Project 2009.
11. Research in Healthy Foods and Products.(INVIAS). CDTI project with Grup Lasem. IDI-20091068.
12. NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and
recycling of polymer nanocomposites used in various industrial applications, NMP-2009-1.3-1, 247899.
13. BIOLUB, Obtention of high performance and environmentally friendly lubricant bases, 09-PR030.
14. Study of dyes and auxiliaries in historical textiles.
17

PUBLICATIONS
1. Exposición: COLORES DEL MEDITERRANEO. ¿Colorantes naturales para un textil sostenible? del 21
de diciembre de 2010 hasta finales de 2012. Lugar: Centre de Documentació i Museu Tèxtil de Terrassa.
2. Monterrat Bargalló, Meritxell DelaVarga, Lorenzo Bautista, Albert Briz, Laurent Aubouy (November
2007). “Dyes from yesterday, colours for tomorrow”, Datatèxtil, 16: 32-49.
3. Aleix Conesa, Lorenzo Bautista, Roshan Paul, Laurent Aubouy, Meritxell DelaVarga. "Dyes from
yesterday, colours for tomorrow: of the history to the new technologies”, Datatèxtil, 19, 60-75, 2008.
4. Leitat Technological Center. "REACH, a great challenge for industry. Pre-register time”, Magazine 3G
Empresarial Girona, Octubre 2008.
5. Leitat Technological Center, “Does REACH leads to residues valorization and recycling?”, Revista de
Plásticos Modernos, 627, September 2008.
6. Meritxell De la Varga, Montserrat Bargalló. “Dyes from yesterday, colours for tomorrow”, II Mostra de
Coneixement, oral communication, 19 de October 2006, Terrassa.
7. “The role of the technological centres and REACH”, Meritxell De la Varga, Oral communication “Impacto
y Gestió de REACH en la Industria” workshop. Barcelona. 30 November 2007.
8. “Recommendations for SIEF constitution”, Alejandra Sánchez Yagüe, Oral communication, “Impacto y
Gestió de REACH en la Industria” workshop. Barcelona. 30 November 2007.
9. "Obligations derived from REACH for the textile industry" workshop in the Textile Industrial Association of
the Cotton Process (AITPA). Barcelona. 4 June 2008.
10. D. Amantia. “Nanoparticles release from textiles Carbon nanotube coating as experimental approach”,
NanoImpactNet Workshops Strategies to standardize nanomaterials for environmental and
ecotoxicological research, Conference, ETH Zurich (Switzerland), 3-5 setembre 2008.
11. “Practical exercise: preregister of chemical substances", in the Informative Conference REACH:
Preregister, organized by Commerce Chamber of Terrassa. 4 November 2008, Marta Escamilla, Oral
Communication.
12. REACH in practise workshop "Obligations for the sector" organized by Asociación Española del Género
de Punto, Natalia Fuentes. Oral Communications. Barcelona. 17 December 2008.
13. Meritxell De la Varga, “REACH in Catalonia and Technological Centres role”, Oral Communication,
Congress: European Chemicals Region Network / REACH Workshop, Aachen (Germany), 2007.
14. José Moltó, Asunción Blanco, Cristina Miranda, José Miranda, Jordi Puig, Marta Valle, Meritxell
DelaVarga, Carmina R Fumaz, Manuel José Barbanoj, Bonaventura Clotet. Variability in antiretroviral
agents concentration in plasma among hiv-infected adults in routine clinical practice, British Journal of
Clinical Pharmacology, 62, 560- 566, 2006.
15. José Moltó, Asunción Blanco, Cristina Miranda, José Miranda, Jordi Puig, Marta Valle, Meritxell
DelaVarga, Carmina R Fumaz, Manuel José Barbanoj, Bonaventura Clotet, Lopinavir/Ritonavir
Pharmacokinetics in HIV and Hepatitis C Virus Co-Infected Patients without Liver Function Impairment:
Influence of Liver Fibrosis, Clinical Pharmacokinetics, 46, 85-92, 2007.
18

FAST MOVING CONSUMER GOODS
Competency Compendium
Dr. Miquel OSSET
Coordinator of the FMCG Division
Email: mosset@leitat.org
Main research fields: Laundry & Home Care.
Equipments:
Hard Surface Scrub Testers
Washing Machine Testing Facilities
Textile Testing equipments
Storage & Stability Areas
Humidity & Temperature Probes
Injection moulding
Tensiometers and Rheometers
Sun Test & Xenon aging chambers
UV-climatic aging chambers
Viscosimeters
Optical microscopy
SPECIFIC RESEARCH INTERESTS
Laundry Testing:
o Primary & Secondary washing performance tests
o Textile testing
o Wash & wear studies
o Ecolabel
o Physical-chemical characterizations
o Stability testing
Hard Surface Testing:
o Scrub & Abrasion Surface Testing
o Shine, foaming, easy rinse, quick & dry profiles
o Optimization of formulations
o New surfactants
o Assessment of Hard Surface Cleaners
o Stability testing
Consumer Goods Product Development:
o Assessment of raw materials suppliers
o Soil release effects
19

o Competitor benchmarking
o New formulations and ingredients
Hygiene and Disinfection in Consumer Goods:
o Disinfection & Biocides acc. to EN Norms
o Hypochlorite-based formulations
o Peroxide-based Laundry Additives
o Long Lasting Hygiene
o Corrosion and irritancy reduction
o Assessment of Biocides
Packaging Technologies:
o Primary Packaging optimizations
o Secondary Packaging optimizations
o Materials Testing
o Graphic & Industrial Design
o Life Cycle Analysis of CPGs –Consumer Packaged Goodso
Carbon Footprint of CPGs –Consumer Packaged Goods-
R&D management in Fast Moving Consumer Goods:
o R&D Strategy (OGSMs, Balance Scorecards, Roadmaps, etc...)
o Management of high performance teams
o R&D Financials
o Key Performance Indicators for R&D
o Consumer Insights
MOST RELEVANT PROJECTS
1. CENIT SEILA “New Technologies for an efficient, ecologic and intelligent washing system for the future
textiles. 2009-2012, CEN20091005.
2. PET-Bleach: PET Bottles for highly oxidizing Bleaches RD09-1-0047
3. EU Ecolabel. Laundry Detergents Performance testing 2010. 07.307/2009/54965/SER/G1
4. EU Ecolabel. Dishwashing Performance Testing -2010-
5. Barcelona Institute of Packaging (2011-2015): project management and implementation of tools &
practices
6. Product Development of Biocides (2010-2011)
7. Product Development of solid laundry additives (2010-2011)
8. Microbiological characterization on textiles (Henkel KGaA 2010-2011)
9. Characterization of Cleaners (KH-Lloreda 2010)
10. Product Development of Industrial Degreassers (Henkel KGaA 2009-2010)
11. Product Development of Bleaches (2010-2011)
12. Analytics of raw materials in detergency: on-going.
20

PUBLICATIONS
1. Detergency for high added value textiles (CED, Barcelona 2010).
2. Study of the interaction of commercial surfactants on new textile products (Dornbin 2010).
3. Formulation of super-concentrated liquid detergents -Draft- (CED, Barcelona 2011).
PATENTS
1. US6204235B1 “Active chlorine preparations containing stabilized optical brighteners”.
2. US6015780A “Formulations for cleaning hard surfaces comprising a betaine surfactant having exactly 12
carbon atoms”.
3. US5750490A “Detergent mixtures”.
4. US5750486A “Low-foaming cleaning formulations”.
5. US5716924A “Aqueous bleaching formulations”.
6. WO2007065581A1 “Stability improvement of liquid hypochlorite-containing washing and cleaning
compositions”.
7. WO2007065525A1 “Increasing the stability of liquid hypochlorite-containing washing and cleaning
compositions”.
8. WO2007079870A1 “Odour reduction for agents contaning hypochlorite”.
9. WO2007079881A1 “Inhibiting the corrosive properties of liquid cleaning agents containing hypochlorite”.
10. WO2007079880A1 “Hand Dishwashing Detergent”.
11. WO2007079859 “Improving the stability of detergents containing hypochlorite”.
12. WO2007079856A1 “Improving the stability of detergents containing hypochlorite”.
13. WO2007025642A1 “Liquid hypohalite bleach”.
14. WO2000077145A1 “Bleaching and disinfecting agents”.
15. WO2000044865A1 “Bleaching and disinfecting agents”.
16. WO2000032735A1 “Active chlorite-containing preparations with stabilized fragrances”.
17. WO2000032730A1 “Peroxy-containing preparations with stabilized fragrances”.
18. WO2000032729A1 “Peroxide-contaning preparations with stabilized optical brightening agents”.
19. WO1995034620A1 “Aqueous dispersions of anionic and cationic surfactants”.
20. WO1995009227A1 “Bleaches and Disinfectants”.
21. DE102005059048A1“Reinigungsmittel für harte Oberflächen”.
21

NANOMATERIALS
Competency Compendium
Dr. David AMANTIA
Team leader of Nanomaterials Unit
Email: damantia@leitat.org
Equipments:
Electrospinning setup MECC NF103 Series
Ultrasonic horn SONICS 750W @ 20kHz
Potential Z, DLS
ICP-Mass
B.E.T. surface area and pore size analyzers QUANTACHROME Nova e-series 2200
Conventional chemical characterization UV-Vis, FTIR-ATR, HPLC.
Pyrolysis furnace N 2 , Ar.
Tensiometer
Tween screw extruder for polymeric nanocomposite
Injection moulding
Other techniques used in external facilities (TEM, SEM, XPS, XRD, TGA…)
Physical and mechanical properties characterization of nanocomposites
SPECIFIC RESEARCH INTERESTS
Chemical Modification and Production of Nanoparticles
Functionalization of carbon nanotube, organic modification of nanoclay, synthesis of magnetite
nanoparticle (Fe 3 O 4 ).
Nanofiber by Electrospinning
Production of aligned and randomly organized polymeric (PAN, PA, PS, Cellulose...) or ceramic
(LiCoO 2 . LiFePO 4 , TiO 2 , SiO 2 ...) nanofibres. Core-shell nanofiber. Carbon nanofiber
Production of nanofibrous membrane for water treatement.
New Nanocomposite
Compounding of nanoclays, nanoparticles and carbon nanotubes in polymeric blends for automotive
parts.
Functionalization of Textiles
Through innovative surface treatments (Sol-Gel, Plasma polymerization, grafting of chemically
modified nanoparticle).
Multifunctional and Smart Materials
Thermochromic and phosphorescent polymer blend, nanoencapsulation by electrospraying and
microemulsion procedure.
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MOST RELEVANT PROJECTS
1. CERAMPOL. Ceramic and polymeric membrane for water purification of heavy metal and hazardous
organic compound. 7 th framework program Collaborative project [NMP.2011.1.2-3] Grant agreement no:
280995
2. nAUTO2. Nanomaterials for automotive industry. Línia d’ajuts a projectes de NUCLIS COOPERATIUS
de Recerca Industrial i Desenvolupament Experimental 2010 Financed by ACC1O 2010 RD10-1-0017
3. NANOTHERM. Tailoring electronic and phononic properties of nanomaterials: Towards ideal
Thermoelectricity. technical programme of the research activity consolider-ingenio 2010 CALL CSD2010-
00044
4. ETF- Energy Technology Future. New concepts for energy storage for medium and large scale
applications. PID-590000-2009-4.
5. SUPERCAP Research and development of new supercapacitors based on electrochemical double layer
and pseudocapacitative effects.
6. NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and
recycling of polymer nanocomposites used in various industrial applications, NMP-2009-1.3-1.
7. Development of flexible upholstery based on fire resistant nanoclays. Financed by the Ministry of
Industry, Tourism and Commerce (2008). IAP-560510-2008-19.
8. Applying carbon nanotube for advanced mechanic properties of protection textile. Financed by the
Ministry of Industry, Tourism and Commerce (2008). NAN2007-30641-E.
9. Electroclay: Development and processing of conductive nanoclays for obtention of multifunctional
conductive polymers. Financed by the Ministry of Industry, Tourism and Commerce (2008). IAP-600200-
2008-49.
10. Nanocit: Design of high added value product based on carbon nanostructure and polymeric resin.
Financed by the Ministry of Industry, Tourism and Commerce (2008). IAP-600100-2008-26.
11. Nanotech: Development of conducting fibres of high resistance using polymers and carbon nanotubes.
Financed by the Ministry of Industry, Tourism and Commerce (2008). FIT-030000-2007-36.
12. Application of nanotechnology for improving mechanical properties of antistatic and fireproof fabrics.
Financed by the Ministry of Industry, Tourism and Commerce (2007). TEX-080000-2007-147.
13. Nanocotton: Application of nanotechnology in textiles for UV protection. Financed by the Ministry of
Industry, Tourism and Commerce (2007). TEX-080000-2007-38.
PUBLICATIONS
1. “Development of protective clothing against nanoparticle based on electrospun nanofibers” Mirko Faccini,
Celina Vaquero, David Amantia. Journal of Nanomaterials. 2012. In Press.
2. “Nanofiber-based filters as novel barrier systems for nanomaterial exposure scenarios” M Faccini, D
Amantia, S Vázquez-Campos, C Vaquero, J M López de Ipiña and L Aubouy Journal of Physics:
Conference Series, 304, 012067, 2011.
3. “Nanofibras y nanoweb por proceso de electrohilatura” Mirko Faccini, David Amantia. Revista de
Química e industria textil (AEQCT), nº 196 enero-marzo 2010.
4. “Reactions of Pd(II) with Chelate-Tethered 2,6-Diaminopurine Derivatives: N3-Coordination and Reaction
of the Purine System”. Galindo MA, Amantia D, Martinez-Martinez A, Clegg W, Harrington RW, Moreno
Martinez V, and Houlton A. Inorganic chemistry 48(23):11085-91, 2009.
5. “Probing metal-ion purine interactions at DNA minor-groove sites” Galindo MA, Amantia D, Martinez
Martinez A, Clegg W, Harrington RW, Moreno Martinez V, and Houlton A Inorganic chemistry
48(21):10295-303, 2009.
23

6. ”Self-assembly of a bis(adeninyl)–Cu(I) complex: a cationic nucleobase duplex mimic”. Miguel A.
Galindo, David Amantia, William Clegg, Ross W. Harrington, Richard J. Eyre, Jonathon P. Goss, Patrick
R. Briddon, William McFarlane and Andrew Houston. Chem. Commun., 2009, 2833 – 2835.
7. “Polyethylene - Montmorillonite Nanocomposite Fibres: Preparation and Properties” Poster presented in
NanoEurope 2007 11-13 September 2007 (St.Gallen, Switzerland).
8. Nano-finishing of cotton yarns and fabrics, Paper presented in CLOTECH’2008, 12-13 June 2008 (Lodz,
Poland).
9. Miguel A. Galindo, David Amantia, William Clegg, et al. “Self-assembly of a bis(adeninyl)–Cu(I) complex:
a cationic nucleobase duplex mimic” Chem. Commun., 2009 First published on the web 2nd March 2009.
10. Cerda, MM; Amantia, D; Costisella, B, et al. “Multiple metal binding to 6-oxopurine nucleobases as a
source of deprotonation. The role of metal ions at N7 and N3”. DALTON TRANSACTIONS. Issue: 32
Pages: 3894-3899, 2006.
11. Amantia, D; Shipman, MA; Price, C, et al. “Conserved supramolecular architecture in polymetallic
nucleobase complexes”. INORGANICA CHIMICA ACTA. Volume: 359. Issue: 11 Pages: 3515-3520.
Published: AUG 1 2006.
PATENTS
1. P201132012. Pere Llobet Padro, Miquel Osset Hernández, David Amantia, Mirko Faccini, Albert Almarza
Martínez, Minerva Fernandez Blanco.
2. ES201030892. Roshan Paul, David Amantia, Lorenzo Bautista, Moises Moron, Helena Esteve, Marolda
Brouta, Jordi Mota, Meritxell De la Varga.
3. ES P2000801874. David Amantia, L. Aubouy, J. Jiménez Romero, Anna Ribé.
ORAL AND POSTER PRESENTATIONS (2011-2010)
1. Advanced nano-materials for automotive industry, IMAGINENANO 2011, Bibao SPAIN, 11-14th of April
2011. Poster
2. Design of high added value products based on carbon nanostructure and polymeric rope and tow strap,
NANOMATERIALS FOR INDUSTRY, Santander SPAIN, 31st of March 2011.
3. Applications of nanofiber in energetic and environment sectors, 5th open day of technological offer in
Catalonia, Manresa SPAIN, 25th of March 2011.
4. Environment-friendly materials for aeronautic applications, OPEN CHINA-EUROPE WORKSHOP ON
AERONAUTICS RESEARCH, Nanjing, CHINA, 25-28th of November 2010.
5. Protective Textile Materials Based on Electrospun Nanofibers, 49th DORNBIRN MAN-MADE FIBERS
CONGRESS. Dornbirn AUSTRIA, 15-17th of September 2010.
6. Nanofiber-based filters as novel barrier systems for nanomaterial exposure scenarios, NANOSAFE 2010.
Grenoble FRANCE, 16-18th of October 2010.
24

ADVANCED POLYMERS
Competency Compendium
Dr. Meritxell MARTÍNEZ-PALAU
Coordinator of Advanced Polymers Division
Email: meritxellm@leitat.org
Equipments:
Twin screw extruder
Extrusion Microcompounder
Mould microinjection machine
Mould injection machine
Melt spinning Monofilament unit
Polymerization reactor
Other facilities:
Portable Drying Conveyors
Triturating mill
Differential scanning calorimetry (DSC)
Thermogravimetric analysis (TGA)
Gel Permeation Chromatography (GPC)
Gas Permeabilimeter
Tensile tester
Charpy impact equipment
Melt flow index / Viscosimeter
Fire resistance testing equipment
Weathering equipment
FTIR-ATR
UV visible
Optical microscopy
SPECIFIC RESEARCH INTERESTS
Synthesis
o Biopolymers
o Biodegradable polymers
o Smart polymers (Shape Memory- Electrochromic-Conductive)
Compounding
o Polymers with natural fillers (woods, cellulose, bamboo…)
o Smart polymers (chromic – luminiscent – PCM)
o Polymers with nano fillers (nanotubes – nanoclays – nanoparticles - nanospheres)
o Active polymers/biosensors
o On demand service
Recycling
o Recycling cycles
o Raw/recycled blends
o Use of out-of-use scraps as polymer fillers
25

Polymerization and crystallization kinetics studies
Polymeric microspheres for controlled drug release
Examples of know-how:
Biodegradable composites from biopolymers and natural fillers
Development of electrically conductive polymers and fibers
Development of wood-plastic composites (WPC)
Development of thermochromic polymers
Development of luminescent polymers and fibers
Development of new HDPE composites with high oxygen barrier
Development of new PP composites with high flame resistance
MOST RELEVANT PROJECTS
1. Valorization and recycling of industrial and post-consumer coffee capsules waste. Industrial project with
Nestlé.
2. Development of WPC with antimicrobial behavior. Industrial project with Ercros.
3. Electrical conductive composites based in PVC formulation. Industrial project with Ercros.
4. Study of the viability of uses of PET residues as reagent for adhesive formulations. Industrial project with
Henkel.
5. Screening, research and development of new PIPA applications. Industrial research with Cepsa.
6. Lightmotorcycle project: Towards a lighter endure and trial competition motorcycle by means of light
composites. R+D projects, Cooperative Nucleus R+D+i RD10-1-0018.
7. nAUTO2 project: Nanotechnology for Automotive applications. R+D Projects, Cooperative Nucleus
R+D+i RD10-1-0017.
8. SUPERTEX, Sustainable Flame Retardant Technical Textile from Recycled Polyester. European project:
Eco-innovation 2011 ECO/10/277225/SI2.596871.
9. GREEN-UP, Improvement of the recycling polyester and leather tanning processes for products focused
on the accomplishment of automotive recyclable upholstery. European project: Eco-innovation 2010,
ECO/09/256111/SI2.579245.
10. CENIT TARGET: Tecnologías inteligentes y medioambientalmente sostenibles para la generación de
estructuras en materiales compuestos. CENIT 2010, CDTI.
11. Development of new composites based on white slags from fundition. Industrial project with Copcisa.
12. PETBleach, PET Bottles for high oxidizing Bleaches ACCIÓ, R+D Projects, Cooperative Nucleus R+D+i,
2009. RD-09-1-0047.
13. Multi.Matheria, Ministry of Science and Innovation, LIA Singular and Strategic Projects, 2008. PSE-
420000-2009- 003.
14. CENIT BioSos, Sustainable Biorefinery, Ministry of Science and Innovation, National Strategic
Consortium Project in Technical Research (CENIT), 2009.CEN 2009040.
15. BoatCycle, Management, recycling and recovery of wastes of recreational boat scrapping, LIFE 08
ENV/E/ 000158.
16. PETAUTO: Development of new and multifunctional PET composites with new properties. CIDEM.
RD08-2-0041.
17. Development of new concentrated biodegradable colour masterbaches. Ministry of Industry, Tourism and
Trade. IAP-560620-2008-67.
18. Development of new films with advanced properties of barrier effect using modified nanoclays. Ministry of
Industry, Tourism and Trade. IAP-560620-2008-62.
26

19. Investigation and development of conducting fibres of high resistance through the use of polymers and
carbon nanotubes. Ministry of Industry, Tourism and Trade. FIT-030000-2007-36.
20. Advanced Biofibres, Financed by Ministry of Industry, Tourism and Trade. FIT-020600-2006-176.
PUBLICATIONS
1. Martínez-Palau, M.; De La Fuente, M.; García, A.; Pérez, G.; Sacristán, M.; Ascanio, Y.; Aubouy, L.
Desarrollo de nuevos materiales con propiedades barrera a partir de nanocargas funcionales. Revista de
los plásticos modernos. Marzo 2012.
2. De La Fuente, M.; Martínez-Palau, M.; García, A.; Sacristán, M.; Aubouy, L. Proyecto PETAUTO:
Desarrollo de nuevos composites de PET con altas propiedades para piezas de Automoció. Revista de
los plásticos modernos. Noviembre 2011.
3. De La Fuente, M.; Martínez-Palau, M.; García, A.; Piñol, L.; Sacristán, M.; Aubouy, L. Nuevos composites
madera-plástico a partir de residuos náuticos. Revista de los plásticos modernos. Diciembre 2011.
4. Martínez-Palau, M; De La Fuente, M.; Briz, A.; Valero, J.; Garrido-Franco, M.; Paul, R.; Bautista, L.;
García-Montaño, J.; Amantia, D.; Aubouy, L.; De La Varga, M. (2009). Nobel Biofibres from
Biodegradable Polymers and Natural Fibres, Naro.Tech, Erfurt (Germany).
5. M. de la Fuente, A. Briz, J. Valero, M. Garrido-Franco, R. Paul, L. Bautista, J. García-Montaño, D.
Amantia, L. Aubouy, M. de la Varga (2008) Novel Biofibres from Biodegradable polymers and cellulosic
fibers. 7th Global WPC and Natural Fibre Composites Congress and Exhibition, Kassel (Germany).
6. M. de la Fuente, A. Briz, L. Bautista, J. Mota, R. Paul, L. Aubouy, M. de la Varga, M. Garrido. (2007)
Polyethylene-Montmorillonite Nanocomposite Fibres: Preparation and Properties” Nanoeurope, St.
Gallen (Switzerland).
Conference Presentations
1. De La Fuente, M.; Martínez-Palau, M.; García, A.; González-Vidal, N.; Piñol, L.; Aubouy, L.
Development of novel Wood Plastic Composites (WPC) using as natural filler wood from the recycling
of leisure sailing ships. 3rd International Conference on Innovative Natural Fibre Composites for
Industrial Applications. Roma (Italy). 12-14 October 2011.
2. Ángel García. Presentació del projecte BOATCYCLE. Saló Nàutic Internacional de Barcelona.
Barcelona. 11 November 2011.
3. Ángel García. Seminari " NUEVOS HORIZONTES PARA LOS RESIDUOS DE ORIGEN PESQUERO
Y PORTUARIO". Casa Llotja de Mar (Barcelona), 22th November 2011.
4. De La Fuente, M.; Martínez-Palau, M.; García, A.; González-Vidal, N.; Piñol, L.; Aubouy, L.
Development of novel Wood Plastic Composites (WPC) using as natural filler wood from the recycling
of leisure sailing ships. Eurotec Conference 2011 (Barcelona), 14 th November 2011.
5. García, A.; Paul, R.; De La Fuente, M.; Martínez-Palau, M.; González-Vidal, N.; Brouta, M. Thermal
stress sensoring system in personal protection equipments for emergency situations. SMARTEX
2011. Kafrelsheikh (Egypt), 22-24 November 2011.
6. Mercè de la Fuente. Investigation and development of novel conductive fibers with high resistance
properties, MFC 2009, Dornbin (Germany).
7. Mercè de la Fuente, Boatcycle: Management,recycling and recovery of wastes of recreational boat
scrapping, Save the Planet Conference 2010, Sofia (Bulgary).
PATENTS
1. PCT/ES2010/070105, New PET composites, L. Aubouy, M. Martinez, G. Sandoval, M. de la Fuente, A.
Garcia.
27

SURFACE TREATMENTS
Competency Compendium
Eng. Lorenzo BAUTISTA
Coordinator of Surface Treatments Division
Email: lbautista@leitat.org
Equipments:
Low-Pressure Plasma (vacuum) and Atmospheric-Pressure Plasma systems (plasma jet, APGD,
ADRE)
Paint booth + paint box
Spray drier
High speed disperser / Homogenizer / Emulsifier
Spray coating, bar coating, spin coating systems
Screen printing, pad printing and inkjet printing systems
Ozone gas equipment
UV curing systems
Ultrasound equipment
Hot plate press for hot melt lamination
Tensiometer and ink test: contact angle and surface tension
Viscosimeters (Brookfield, Ford viscosity cups)
Density of paints, coatings and inks
Spectometer UV-Vis Spectraflash (colour density, opacity, yellowing, etc.)
Particle size and fineness of grind for paints, pigments, inks, coatings, etc.
(Nano)particle size and distribution (DLS), Z-potential
BET surface area and porous size analyser
FTIR-ATR (ATR Ge crystal) and UV-Visible spectrometers
Adhesion and peeling tests
Air permeability testers / Water permeability analyzers / Vapour permeability
Heat transmission rate analyzer
Electrochemical characterization equipment
Microscopy Laboratory
Microbiological Laboratory
Mechanical, thermal, rheological and electrostatic analysis of coated and painted materials
Accelerated ageing of coated materials
SPECIFIC RESEARCH INTERESTS
Paints, coatings and printing inks:
o
o
o
Technologies: liquid or powder coatings, printing inks, nanocoatings by PECVD processes,
grafting induced by plasma, sol-gel coatings.
Formulation: solvent or water-borne coatings, dispersion of pigments (Cowles, ball milling),
rheological properties, wetting properties, green solvents, role of additives;.
Application: paint booth with temperature control.
28

o
o
Drying/curing: UV or thermal.
Properties: hydrophobic, oleophobic, hydrophilic, oleophilic, antimicrobial, UV protection,
barrier properties, abrasion resistant, self-cleaning, anticorrosion, thermal resistance,
electrical conductivity, IR reflecting, thermochromic and photoluminescent, among others.
Microencapsulation technologies:
o
o
o
o
o
Why?: to avoid the degradation of the core, masking odors, protecting the core during the
processing, controlled-release, self-healing paints and coatings.
Microencapsulation methods: chemical (coacervation, emulsion, etc.) and physical (spray
drying) methods.
Core: flavors, biocides, pigments, enzymes, vitamins, etc.
Shell: polyamide, chitosan, gelatin, ethyl cellulose, etc.
Industrial sectors: food, cosmetic, pharmaceutical, textile, plastics, aeronautical, detergency,
building, etc.
Preparation of surfaces:
o
o
Technologies: degreasing, surface pretreatments, plasma, ozone.
Properties: wetting and adhesion improvements before painting, coating, printing, laminating,
gluing, etc.
Decontamination of surfaces:
o
o
Technologies: plasma, UV radiation, ultrasounds, ozone, photocatalysis.
Properties: elimination of microorganisms (bacteria, fungi, yeast).
Chemical and morphological surface analysis: FTIR-ATR, SEM, static and dynamic contact angle.
MOST RELEVANT PROJECTS
1. PIRECO: New formulations of paints and coatings with high antiadherence properties for external parts
of cars, R+D+i Cooperative 2009, ACCIÓ, 2009-2011. RD 09-1-0093.
2. SEILA: New technologies for an efficient, ecological and intelligent textile washing system for the future,
CENIT 2009, 2009-2012. CEN20091005.
3. INSEPLATEX: Development of functional plastics and textiles with repellent and insecticide effects,
R+D+i Consorciado 2009, ACCIÓ, 2009-2011. PID-600300-2009-12.
4. ECOMOVIN: Alternative ecofriendly materials for the interior of transport systems, R+D+i Cooperative
2009, ACCIÓ, 2009-2011. RD 09-1-0061.
5. ADRESURFOOD: Investigación y Desarrollo de la Tecnología ADRE para el Control Higiénico en
Superficies Alimentarias, MITYC, Invest In Spain 2010, 2010-2011, ID: C1_10_39.
6. MICROSEGA: Microcápsules biopolimèriques per aplicacions de seguretat alimentària, AGAUR, Valor
2010, 2011-2012.
7. MICROFLEX: Microfabrication technologies for flexible substrates, NMP-2007-3.5.2, CP-IP 211335-2,
2009-2012.
8. AMICOAT: Antimicrobial nanostructured durable coatings for fuel tanks, Clean Sky 2011, 2012-2013.
9. ZOOBIOTECH: Aplicació d’extractes derivats de cultius de cèl·lules vegetals meristemàtiques
modificats mitjançant tractaments biotecnològics, Eurotransbio 2011, 2012-2013.
10. BIP: Modificació superficial de packaging i tintes intel·ligents (subactuació 2), Plans d’actuació d’agents
TECNIO 2001, ACCIÓ, 2011-2012.
29

11. ITACA: Investigación de tecnologías de tratamiento, reutilización y control para la sostenibilidad futura
de la depuración de aguas, INNPRONTA 2011, 2011-2014.
12. INNOFOTO: Novel immobilised photocatalysts for polluted air treatment, Proyectos de Investigación
Fundamental no orientada 2011, CIEMAT-UPM-LEITAT, 2012-2014.
PUBLICATIONS
1. L. Bautista. “Aplicación de AFM en la caracterización superficial de recubrimientos textiles basados en
tecnología de plasma y sol-gel”, I Jornadas de Microscopia de Sonda Próxima Aplicada a Empresas,
Barcelona, 28-10-2010.
2. Lorenzo Bautista, Laia Crespo, Jordi Mota, Meritxell de la Varga. “Nanorrecubrimientos basados en
tecnología de polimerización por plasma”, Jornada AIN 2010 Barcelona, 09-06-2010.
3. L. Bautista et al. “Effect of the type of gas and temperature during atmospheric pressure glow discharge
treatments on LDPE films”, Plasma Surface Engineering (PSE 2010), Garmisch-Partenkirchen,
Germany, September 13 - 17, 2010.
4. Helena Esteve, Marolda Brouta, Laia Crespo, Roshan Paul. “Desarrollo de textiles con valor añadido
mediante microencapsulación”, Revista de Química e Industria Textil, 197: 58-59, 2010.
5. Llorenç Bautista, Jordi Mota, Laia Crespo, Meritxell de la Varga, “Atmospheric Pressure Plasma
technology for textile applications”, 37 Simposium de la AEQCT, 6-7 June 2011, Barcelona (Spain).
6. L. Crespo, A. Serret, R. Paul, L. Bautista, H. Esteve, M. De la Varga, A. Surribas, “Synthesis and
characterization of antibacterial chitosan microspheres for textile applications”, XIX International
Conference of Bioencapsulation, 5 August 2011, Amboise (France).
7. Jordi Mota, Laia Crespo, Llorenç Bautista, “Research and devolopment of bio-based chemistry in
Leitat”, Eurocoat 2011, 27-29 September 2011, Paris (France).
8. L. Bautista, M. Batsiolas, J. Mota, L. Crespo, M. de la Varga, R. Paul, Ch. Pavan, “Surface-modıfıed
polyester filters by APGD treatments”, 50th Dornbirn MFC, 14-16 September 2011, Dornbirn (Austria).
9. R. Paul, M. Osset, M. Fernández, L. Bautista, J. Mota, L. Crespo, M. Faccini, A. Machin, C. Malet,
“Interaction of surfactants on new textile products”, Melliand China, 2011, 10: 42-44.
10. M. B. Della Pirriera, P. Bosch-Jimenez, L. Aubouy, D. Gutiérrez-Tauste, J.M. García-Torres,
J.L.Bautista. “DSSC with large stokes shift layer as UV blocking layer”, 4th international Conference on
Hybrid and Organic Photovoltaics (HOPV2012), 6-9/5/2012, Uppsala (Sweden).
11. M. B. Della Pirriera, P. Bosch-Jimenez, E. Torralba, D. Gutiérrez-Tauste, D.Amantia, M.Faccini, L.
Bautista, J.M. García J. A. Saez, F. Agustí, “Eu photolumiscence paste for PV”, Proceedings Largearea
Organic & Printed Electronics Convention (LOPE-C 2012), June 19-21, 2012, München
(Germany).
12. L. Bautista, J. Mota, L. Crespo, J. M. García, M. Martínez, L. Aubouy, "Poly(acrylic) nanocoatings
deposited by AP-PECVD processes on paper substrates for packaging applications", Plasma Surface
Engineering (PSE 2012), September 10 - 14, 2012, Garmisch-Partenkirchen (Germany).
PATENTS
1. L. Aubouy; L. Bautista; E. Crespo; J. Pla; P. Andrés. “Revestimiento de cromatismo variable para la
decoración de superficies” P200802629.
2. Roshan Paul, David Amantia, Lorenzo Bautista, Moisés Morón, Helena Esteve, Marolda Brouta, Jordi
Mota, Meritxell De la Varga. “Tejidos funcionalizados con nanotubos de carbono”, Marina Textil S.L.,
PCT/ES201030892.
30

TEXTILE TECHNOLOGIES
Competency Compendium
Eng. Javier JIMENEZ
Coordinator of Textile Technologies Division
Email: jjimenez@leitat.org
Dr. Roshan PAUL
Principal Investigator of Textile Technologies Division
Email: rpaul@leitat.org
Equipments:
Yarn winders and weaving machines
Circular and flat knitting machines
Dyeing and finishing machines for fibres, yarns, fabrics and garments
Padding mangles and coating equipments
Digital and screen printing machines
Electrostatic powder spray guns
Industrial thermo-sealing machine and sewing machines
Hot plate press for hot melt lamination
Testing equipments for chemical, mechanical and physical properties of textiles
Accreditations:
EXP.18LE026 – Wool and textile products
EXP.18LE274 – Burning behaviour
EXP.LE705 – Personal protective equipments
OC-L/023 – Notified Body for PPE
SPECIFIC RESEARCH INTERESTS
Technical textiles: Development of technical textiles for construction, automotive, marine,
aeronautical, agricultural and environmental sectors.
Smart textiles: New functionalities on textiles by incorporating electronics and functional finishes.
Medical textiles: Superabsorbents, medical textiles and sutures for personal use and operation
theatre.
Non-wovens: Geotextiles, felts and filters with functional properties.
Personal protective equipments: Development, modification and applications.
Nanotechnology applications: For developing multifunctional textiles: self-cleaning, UV protection,
antibacterial, hydrophobic, oleophobic, antistatic, abrasion resistant, fire retardant, etc.
Sol-gel finishing: Nanocoatings on textiles and non-wovens
Plasma applications: Pretreatment and finishing of textiles and non-wovens.
Biotechnological applications: Enzymatic pre-treatments, bio-finishing, denim washing, application
of pharmaceutics, antibacterial treatments, etc.
Microencapsulation: Development and application of microcapsules for fibres and textiles.
Spray coatings: Liquid and electrostatic powder spray coatings and finishes.
Natural products: Application of natural dyes, natural products and natural finishes.
Natural fibres: Utilization bast fibres like flax, hemp, jute, pineapple, etc. for clothing and insulation.
Cosmetic textiles: Application of cosmetic finishes and testing of cutaneous irritability.
Textile recycling: Reuse of textile waste for technical and environmental applications.
31

MOST RELEVANT PROJECTS
1. CAPCARE: Natural hair dyes with lesser sensitibility, CDTI - PID Individual 2011.
2. ALBATROS: Development of a new personal security system for sea life based on new materials that
can be integrated in the on-board clothing, CDTI, IDI-20100713 - 2010.
3. GREENUP: Improvement of the recycling polyester and leather tanning processes for products focused
on the accomplishment of automotive recyclable upholstery, CIP Eco-Innovation-2009,
ECO/09/256111/SI.579245.
4. ECOMOVIN: Alternative eco-friendly materials for the interior of the means of transport, ACC1Ó - RD09-
1-0061.
5. SEILA: New technologies for an efficient, ecologic and intelligent washing system for the future textiles,
CENIT 2009. CEN20091005.
6. INSEPLATEX: Development of plastics and textiles with insect repellent and insecticide effects, LIA
I+D+i 2009 – CONSORCIADO, PID-600300-2009-12.
7. SAFEPROTEX: High-protective clothing for complex emergency operations, FP7-NMP-2008-SME-2,
228439.
8. PROFITEX: Providing fire fighters with technology for excellent work safety, FP7-NMP-2008-4.0-9,
228855.
9. T-POT: Unlocking the Croatian textile research potentials, FP7-REGPOT-2008-1, 229801.
10. FIBNATEX: Production and technical evaluation of natural fibres for the textile industry of the Southwest
Europe, INTERREG IVB SUDOE 2008, SOE1/P1/P188.
11. Improvement of whitening effect and the dyeing yield by means of the application of hydrolyzed protein
on cotton and chrome tanned leather, LIA I+D+i 2008. IAP-560510-2008-26.
12. MICROFLEX: Micro fabrication production technology for MEMS on new emerging smart
textiles/flexibles, NMP FP7-NMP-2007-LARGE-1, 211335.
13. UV-TUBE: UV curable yarn finishing with carbon nanotubes to obtain yarns with good permanency of
conductive properties, MNT ERA-NET Transnational Call 2007, NAN2007-30641-E.
PUBLICATIONS
1. Paul R., et al. 2012. Hydrolyzed collagen: A novel additive in cotton and leather dyeing. Dyes Pigm. 94.
475-480.
2. Paul R., et al. 2012. Chapter 10. Protective insulation materials in Functional Protective Textiles, Edited
by Bischof S., Published by University of Zagreb, Croatia. ISBN 978-953-7105-45-7, pages 281-303.
3. Brouta-Agnésa M., 2011. Innovative textiles based on hemp fibres. Rev. Química e Ind. Textil. 205. 30-
33.
4. Ribé A., et al. 2011. PALF: New opportunities for pineapple leaf fibres. Rev. Química e Ind. Textil. 204.
52-56.
5. Paul R., et al. 2011. Nano-finishing of textiles by sol-gel technique. Asia. Dyer. 8 (4). 30-34.
6. Paul R., et al. 2011. Interaction of surfactants on new textile products. Mell. Inter. 17 (2) 88-91.
7. Paul R., et al. 2011. Technical applications of coir fibres. Rev. Química e Ind. Textil. 201. 28-31.
8. Paul R., et al. 2010. Nano-cotton fabrics with high ultraviolet protection. Text. Res. J., 80 (5), 454-462.
9. Ribé A. Saúde Project: Development of foot protection equipment for fishermen of Galicia. Rev. Química
e Ind. Textil, 199, 50.
10. Paul R., et al. 2010. Ecological dyes and mordants: A solution for the environment. Quím. Textil, 33
(100), 42.
32

11. Esteve H., et al. 2010. Development of value added textiles by means of microencapsulation. Rev.
Química e Ind. Textil, 197, 58.
12. Ribé A., et al. 2010. SAÚDE Project for improving the work conditions. Rev. Inno. Textil, 8, 24.
13. Brouta M. 2010. Hemp fibres: extraction and applications. Rev. Inno. Textil, 8, 22.
CONFERENCE PRESENTATIONS
1. Paul R., et al. “Multifunctional Textiles by Plasma Treatments and Nanofinishing”. The Fourth
International R&D Project Proposals Brokerage Event in Textiles and Clothing, Bursa, Turkey, 2-3
February 2012.
2. Paul R. et al. “Bast Fibre based Multifunctional Home Textile Products” The Fourth International R&D
Project Proposals Brokerage Event in Textiles and Clothing, Bursa, Turkey, 2-3 February 2012.
3. García A., et al. “Thermal Stress Sensoring System in Personal Protection Equipments for Emergency
Situations”. SMARTEX-2011: 1st World Textiles Conference, Kafrelsheikh University, Egypt, 22-24
November 2011.
4. Crespo L. et al. “Synthesis and Characterization of Antibacterial Chitosan Microspheres for Textile
Applications”. XIX International Conference on Bioencapsulation, Amboise, France, 5-8 October 2011.
5. Esteve H. et al. “New Horizons in Textile Research”. 11th Narrow Fabric Conference (Jakob Müller),
Barcelona, 21 September 2011.
6. Paul R., et al. “Conductive Fabrics using Carbon Nanotubes”. 50th Dornbirn Man-made Fibers Congress,
Dornbirn, Austria, 14-16 September 2011.
7. Crespo L., et al. “Chitosan Microspheres for Antibacterial Finishes”. AUTEX 2011 World Textile
Conference, Mulhouse, France, 8-10 June 2011.
8. Paul R., et al. “FIBNATEX PROJECT: Innovative Textiles from Hemp Fibres”. 37 Simposio de la AEQCT:
La Industria Textil en los Próximos Años, Barcelona, Spain, 6-7 April 2011.
9. Paul R. “FIBNATEX PROJECT: Benefits of Industrial Hemp”. AGRIGANGA: II Feria Agrícola, Ganadera,
Agroalimentaria, Nuevas Tecnologías y del Medioambiente de Láchar, Láchar, Spain, 26 March 2011.
10. Surribas, A., et al. “Biotechnological Cotton Processing”. 7th International Conference on Polymer and
Textile Biotechnology, Milan, Italy, 2-4 March 2011.
11. Brouta M., et al. “Advanced Textile Coatings based on Sol-Gel and Plasma Technologies”. International
Conference on Textile Coating and Laminating 2010 (TCL 2010), Cannes, France, 4-5 November 2010.
12. Paul R., et al. “Study of the Interaction of Commercial Surfactants on New Textile Products”. 49th
Dornbirn Man-made Fibers Congress, Dornbirn, Austria, 15-17 September 2010.
PATENTS
1. WO 2011/148136 A2. C. Hijosa, A. Ribé Gallart, J. Jiménez Romero, R. Paul, M. Brouta-Agnésa.
2. WO 2011/151074 A2. D. Van de Vyver, F. Godefroidt, D. Luyckx, L. Chaboche, K. Eufinger, R. Paul, M.
Vanneste, M. Van Parys, X. Decant, H. Esteve.
3. ES P2349823 A1. J. Mota, H. Esteve, L. Bautista, D. Amantia, R. Paul, M. Morón, M. de la Varga, M.
Brouta-Agnésa.
4. ES P200801040. D. Amantia, L. Aubouy, A. Ribé, J. Jiménez Romero.
5. ES P200801878. L. Aubouy, J. Jiménez Romero, J. Sáez Zamora, A. Ribé Gallart
6. ES P200702271. L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez.
7. ES P200702272. L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez.
8. ES P200702273. L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez.
33

SMART SYSTEMS
Competency Compendium
Eng. José SAEZ
Coordinator of Smart Systems Division
Email: jasaez@leitat.org
Main research fields: Electronics and Smart Systems.
Equipments:
Rapid PCB Prototyping
Multimeters and Oscilloscope
Laboratory Function Generator and Power supplies
Digital printing Inkjet
Screen Printer Equipment
Thermo sealer
Textile integration workshop
Digital Data logger
Humidity and temperature probes
Thermo graphic camera
Mechanical and electronic Workshop
Electronic design and simulation software
µ-processor development set
Zig Bee development kit.
Potentiostat/Galvanostat
Calorimeter.
Other Available Facilities:
Climate Simulation Chambers
Rapid Plastic Piece Prototyping
Sun Radiation Simulation Chambers
Textiles testing equipments (Dynamometer, abrasion, pressure test equipments, pilling test
equipments, Uster regularimeter, mobile colorimeter, refractory furnaces, flame retardant tests…)
Point and warp looms
Frame stamping equipment
SPECIFIC RESEARCH INTERESTS
• Thermoelectricity:
o Specific applications design and prototyping.
o Custom made thermoelectric modules development.
o Thermal requirements calculation and simulation.
• Medical devices:
o Custom made portable devices.
o Bio-parameter monitoring devices.
34

o Bio-sensors.
• Energy harvesting:
o Renewable energy sources.
o Self-powered devices.
o Energy harvesting modules design and development.
• Smart Systems:
o Sensors and actuators development and integration.
o Wireless communications.
o Firmware development.
• Energy Storage
o Li-ion Batteries.
o Supercapacitors.
• E-Textiles:
o Electronic integration in Smart Textiles.
o Electronics on flexible substrates.
o Flexible and stretchable conductive materials.
• Prototype development:
o Renewable energies applications.
o Electronics applied to high performance sports.
o New commercial products.
o Small production series custom-made devices.
MOST RELEVANT PROJECTS
1. Microflex: microfabrication technologies for flexible substrates. NMP-2007-3.5.2, CP-IP 211335-2.
2. Bio-ICN: Biosensor for fast detection of breast cancer. Industrial Funding.
3. VACMON: biosensor for fast vaccine monitoring. PID-560200-2009-2.
4. MAS: Mobile Ambient Assisted Living. 2009 ENIAC Joint Undertaking. Grant Agreement Nº120219.
5. CSSL: Consumerizing Solid State Lighting. 2009 ENIAC Joint Undertaking. Grant Agreement Nº120228.
6. VERDE: Research and knowledge generation about the manufucture and integration of the full electric
vehicle in Spain Ministry of Science and Innovation, National Strategic Consortium Project in Technical
Research (CENIT), 2009.
7. END: Models, solutions, methods and tools for energy aware design. 2009 ENIAC Joint Undertaking.
Grant Agreement Nº120234
8. ASTUTE: Pro-active decision support for data –intensive environments. ARTEMIS Joint Undertaking.
Grant Agreement Nº269334.
9. NANOTEG: Nanostructured Thermoelectric Systems for Green Transport & Energy Efficient Applications.
2010 Eniac Joint Undertaking. Grant Agreement Nº270689-2.
10. E2SG: Electronic and communication systems for the integration of renewable energy sources into Smart
Grid. 2011 ENIAC Joint Undertaking. ENIAC-ED-52 v161210.
11. DEMANES: Design, Monitoring and Operation of Adaptive Networked Embedded Systems. ARTEMIS
Joint Undertaking. Grant Agreement Nº295372.
12. ITACA: Research in technologies water treatment, reutilization and control to allow future sustainability in
residual water management.
35

PUBLICATIONS
1. Javier Jimenez, José Saez, Laurent Aubouy “Smart Playpen”, TUT, 2007, 63, 15.
2. J. Jiménez, L. Aubouy, J. Sáez, L.Bautista, A.Briz, M. DelaVarga y J. Parra “A general view on the
future of textile sector“ (1)”, Revista de la Industria textil, 2007,447,22-40.
3. J. Jiménez, L. Aubouy, J. Sáez, L.Bautista, A. riz, M. DelaVarga y J. Parra “A general view on the
future of textile sector (2)”, Revista de la Industria textil, 2007, 448,6-13.
4. A. Detrell, J. Jiménez, L. Aubouy, J. Sáez, L. Bautista, A. Briz, M. DelaVarga y J. Parra, “The textile
recovers life”, Diffusion Sport Magazine, 2007, 112, 68-78.
5. D. Gutierrez, L. Aubouy, C. Largeot, M. Faccini, J. Suarez, J. Saez. “Ultracapacitors: Adding power to full
and hybrid electric vehicles”.
PATENTS
1. ES P200702271. L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez
2. ES P200702272. L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez
3. ES P200702273. L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez
4. ES P200702438. A. M. Jiménez Maroto, L. Aubouy, J. Sáez Zamora, J. Jiménez Romero
5. ES P200801874. L. Aubouy, J. Jiménez Romero, J. Sáez Zamora
6. ES P200801875. L. Aubouy, J. Jiménez Romero, J. Sáez Zamora
7. ES P200801876. L. Aubouy, J. Jiménez Romero, J. Sáez Zamora
8. ES P200801877. L. Aubouy, J. Jiménez Romero, J. Sáez Zamora
9. ES P200801878. L. Aubouy, J. Jiménez Romero, J. Sáez Zamora
10. ES P200931236. J.A. Sáez Zamora, J. Suarez Jiménez, F. Agustín Mora, F.A. París Casadelles, D.
Tutusaus Martínez.
36

NEW PRODUCTION PROCESSES
Competency Compendium
Eng. Magí GALINDO ANGUERA
Coordinator of the New Production Processes Division
Email: magigalindo@leitat.org
Main research fields: Product and Process Design and Development, Advanced manufacturing
technologies: Additive manufacturing, Robotics and Artificial Vision.
Equipments:
CAID, CAD and CAM facilities equipped with:
o Catia V5 R17 and Solidworks 2010
o Wacom Cintiq 21UX tablet with Photoshop CS3
o Dimension, Additive layer manufacturing system from Stratassys
o Reverse Engineering software: Polyworks Modeller, Nurbs and Inspector
o Structured light 3D scanner Sidio Pro and digitizer software Triple
Software CAE : Ansys Workbench Mechanical /Thermal
Production facilities equipped with:
Coesfeld, CNC milling machine + Galaad Integrated CAD/CAM/CNC software
Injection Molding Machine
Polymer Extrusion Machine
Workshop equipped with auxiliary machinery.
Analysis and Characterization facilities:
Mechanical Characterization Laboratory
SPECIFIC RESEARCH INTERESTS
Product and Process Design and Manufacturing: Creation of new products and redesign of existing ones
using transformation design techniques. Focused on clear understanding of roles and expected behaviour of
products, designing new products or revised versions of existing products and identifying market and product
applications. Planning of production processes based on general characteristics of the product, in the
material, surface finishes, tolerances, production tools, machines, assembly and speed or production rate, etc.
Software CAD/CAE/CAM and Reverse Engineering: The engineering design supported by CAD / CAE
techniques allows optimization of the product before manufacturing assisted by CAM tools, the management
of rapid product development and the advance of the start of production.
Reverse Engineering (RE) allows the generation of surface models using 3D scanning techniques and thus
allows the production of both parts and tools.
The aesthetic and ergonomic products demanded by the market need for ever more complex shapes that
CAD systems can not solve for themselves. The reverse engineering provides solutions to the request of
constantly reducing development time and the need to form increasingly complex new products.
Additive Manufacturing Technologies and their industrial applications: These technologies are used to
directly construct three-dimensional models and end-use products from electronic data. An additive
manufacturing system use CAD data to build parts layer by layer in very thin cross-sections. Our focus is
37

placed on the technologies –software, hardware, materials and processes- that help conceive, test, improve
and manufacture new products to bring them to market faster and most cost effectively.
Machining and Material Removal, Molds, Tools and Dies Design and Manufacturing: As part of the
overall process of product development from conceptual stage to its industrialization, we pay particular
attention to the more conventional systems of both production and processing of polymeric and metallic
materials.
CNC machining systems as a set of core technologies of production; design and construction of injection
molding or die casting; designing and building of special tools and testing tools are part of our research
interests too.
Automated Manufacturing and Assembly, Computer Integrated Manufacturing and Robotics, Artificial
Vision Systems and Digital Image Processing: Robotics sensors and intelligent grippers, Industrial control
systems integration, Testing and measurement automation, New robotic functionalities and application areas
Identification Systems and Part Traceability by means of RFID or Artificial Vision, Smart navigation systems.
MOST RELEVANT PROJECTS
1. Smart System: New bumper with active schock absorber. RD09-1-0043
2. SAM: Safety drug delivery. Cooperative Nucleus R+D+i RD09-1-0098-00
3. Lightmotorcycle: New materials and designs to obtain lighter motorcycles. Cooperative Nucleus R+D+i,
RD10-1-0018
4. Argos. New robot platform with autonomous navigation and smart surveillance system.Cooperative
Nucleus R+D+I, RD10-1-0019
5. Nocosot project aims to design and develop a new underground container for collecting waste, based on
an innovative concept. IEDES11-1-0155
6. Defecto Zero aims to eliminate manufacturing defects through the design, development, implementation
and validation of a flexible dimensional inspection system on the vehicle production line to ensure
production quality in real time and correct the process in a flexible manufacturing system by an intelligent
defects assessment. IDI-20111479.
7. Target project goal is to research and develop smart and environmentally sustainable new technologies
for the generation of structures in composite materials. Research focuses on materials, both existing and
new, and processes to eliminate the use of large autoclaves, whilst providing the necessary knowledge
bases for the development of new concepts in machinery and automation for the mentioned processes.
CEN-20101004
8. 3D LightTrans: Large scale manufacturing technology for high-performance lightweight 3D
multifunctional composites. The goal of the project is to create a highly flexible manufacturing chain for
low cost production of integral large scale 3D TRPC parts, based on innovative approaches for the
individual processes and its integration in the complete supply chain. FP7-NMP-263223
9. Grain. The main objectives of GRAIN are to identify and assess the future development of large scale
simulation methods and tools needed for greener technologies to deeper understand and minimize the
effects of aircraft/engine design on climate and noise impact, reaching the Vision 2020 environmental
goals. FP7-TRANSPORT-266184
10. Restoration. Research and innovation for advanced multifunctional ceramic materials. Resorbable
Ceramic Biocomposites for Orthopaedic and Maxillofacial Applications. New Production Processes team
leads the research and development of finite element and dissolution/bone remodelling models to predict
the mechanical performance of the devices over time. FP7-NMP-280575
38

PUBLICATIONS
Oral presentations and Congress contributions
1. “Current and available technologies of Rapid Prototyping and Rapid Tooling. Industrial examples”. NEW
TECHNOLOGIES IN RAPID PROTOTYPING. Parque tecn. de Barcelona, Barcelona (March 25 th , 2004).
2. “Advances and trends in Rapid Prototyping y Rapid Manufacturing”. FORUM MAQUITEC 2004.
Barcelona (October 21 st , 2004).
3. “Preliminary point and requirements for the use of SFF systems”. I TECHNICAL FORUM OF THE RP &
DM IN THE INDUSTRIAL FOUNDRY in ETR, Ripoll (November 24 th , 2005).
4. “RM the beginning of a new industrial revolution and a source of new business opportunities”. II RM
TECHNICAL FORUM. Girona (December 14 th , 2006).
5. “RM, new business opportunities for Industrial Designers”. Conference new opportunities of business
with the Rapid Manufacturing. ADI-FAD, Barcelona (June 17 th , 2008).
6. “RM state of the art, processes, materials and applications”. I One Day Seminar on RM: Manufacturing
Reinvented. Institut Químic de Sarrià, Barcelona (November 11 th , 2008).
7. "Technologies of advanced manufacture and its application to the medical technologies”. RM Forum. 2nd
Edition. Manufacturing reinvented for medical and biomedical applications. Institut Químic de Sarrià,
Barcelona (June 29 th , 2009).
8. “Unleashing AM through software solutions” AM Forum 3 rd edition. the third workshop on Additive
Manufacturing held at Diseny HUB Barcelona, June 28 th , 2010.
Seminars and workshops
1. “Prototyping in the product development". 4 hr Session belonging to the Master in Production and
Engineering Integrated for Computer and at the Postgraduate Course in Development of Engineering of
Product (ICT / UPC). BLOC C: VERIFICATION AND REDESIGN OF PRODUCTS. Technologies to
obtain prototypes. Traditional techniques. Rapid Prototyping. The prototyping in the projects of product
engineering. Exhibition of real cases. Coordinated course for Felip Fenollosa (Director of operations of
the Centre CIM. Place: CIM Center, C. Llorens i Artigas 1-2, 08028 Barcelona.
2. “Rapid prototyping in the Design of Product". 4 hr session belonging to the Technical Postgraduate
Course CAD /CAM (ICT / UPC). Rapid Prototyping of product. Linking between CAD and RP. Technologies
for the fast manufacture of prototypes. Coordinated course for Felip Fenollosa (Director of operations of
the Centre CIM. Place: CIM Center, C. Llorens i Artigas 1-2, 08028 Barcelona.
3. “Technology of materials and Technologies of production in the area of the additive manufacture." 8 hr
sessions belonging to the Fourth and Fifth Course of Industrial Engineering. Technologies and materials
for the direct manufacture or Rapid Manufacturing. Coordinated course for Dr. Salvador Borrós and Dr.
Guillermo Reyes of Institut Químic de Sarrià. (IQS) Via Augusta 390, 08017 Barcelona.
4. Participation as speaker in different formation seminars of the technologies of RP/RT and RM in
companies like Roca Radiadors (Gavà), SEAT and EDAG (Martorell), Mercedes Benz (Vitoria),
Ficocables and Sogefi Filtration (Rubí), Valeo Climatització, Ficomirrors and Zanini (Mollet), IMC Toys
(Terrassa), HUF (Burgo de Osma-Soria), ESPA Bombas Eléctricas (Banyoles) etc., and in seminars
organized by DRL and PROTOMOLD in Argentona, Cabrils, Vigo... oriented to companies of the
automotive sector and of the industry of the transformation of plastic in general.
PRIZES
1. B-Here, honorable mention –second prize- of the Sustainability and Architecture Association (ASA) design
contest "KBXXI: Barcelona’s 21 st century Kamishibai."
PATENTS
Spain Patent num. 201230454, for "DISPOSITIVO PARA APLICAR ADHESIVO DESDE UN VIAL O
AMPOLLA DE PAREDES DEFORMABLES Y KIT DOSIFICADOR DE ADHESIVO QUE INCLUYE DICHO
DISPOSITIVO APLICADOR"
39

ENVIRONMENT
Competency Compendium
Dr. Julia GARCÍA-MONTAÑO
Coordinator of Environment Division
Email: jgarcia@leitat.org
Equipments:
Total Organic Carbon (TOC) analyzer
Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) equipment
N kjeldahl
Adsorbable Organic Halogens (AOX) analyzer
Microtox instrument (acute toxicity)
GC-MS, LC-MS, HPLC-PDA, Ion Chromatograph
ICP-MS
Respirometer for biodegradability assessment
Equipment for the microbiological analysis of water
Advanced Oxidation Processes (AOPs) reactors and photo-reactors
Electrocoagulation and Electrooxidation and electrowinning cells
GE Osmonics filtration equipment (flat membranes)
N 2 Filter (Millipore)
MMS laboratory filtration membrane equipment (spiral, tubular and hollow fiber membranes)
MMS pilot filtration membrane equipment (spiral, tubular and hollow fiber membranes)
Ceramic membrane filtration equipment
Laboratory equipment of aerobic biological treatment
Aerobic biological treatment pilot plant
Physic-chemical treatment pilot plant
Anaerobic biological treatment pilot plant
MBR treatment pilot plant
Filter press equipment
Jar-test
Portable Turbidimeter
Refractometer
SDI equipment
Portable MultiParametric probe
Nasal Ranger field olfactometer
Portable Single Gas Detector
SPME fibers
Vertex uptake pump
Thermal desorber
Dispersion Software
SimaPro LCA software
40

SPECIFIC RESEARCH INTERESTS
Water treatment: Alternative water treatment technologies: Electrochemical processes
(Electrocoagulation, Electrooxidation, Electrowinning and Electrodyalisis ), Nanotechnology
(nanoparticles and nanofibres for water filtration), Biotechnology (enzymes), Microalgae; Advanced
Oxidation Processes (Fenton type reactions, heterogeneous photocatalysis, Ozone); Membrane
processes (Reverse Osmosis, Microfiltration, Ultrafiltration, Nanofiltration), functionalised membranes for
selective filtration; Biological Treatments (aerobic, anaerobic), Microbial Fuel Cells, Wetlands,
Biosorption; combined treatments; high added value products recovery and valorisation.
Minimisation of water consumption: optimisation and design of new productive processes, generation
of new water resources, water reuse.
Alternative energy generation: energy production from wastewater, energy savings for water recovery.
Emergent contaminants detection and quantification: dyes, drugs, nanoparticles,...
Waste minimisation and waste valorisation: optimisation and design of new productive processes,
high-added value products isolation and valorisation.
Energy from biomass residues and wastes: feasibility analysis of biomass supply (extracting forest
biomass, biomass residues, energy crops, microalgae, sewage sludge, natural drying studies,
transportation); physical, chemical and energy valorisation of biomass (feasibility analysis:
pelleting/briquetting/chipping, combustion, gasification and pyrolysis technologies, CHP, power
generation, composting biological treatments, anaerobic digestion).
Air Quality – ODOURS: indoor and outdoor COV’s and odours studies. Chemical and sensor methods,
photocatalytic treatment of contaminated atmospheres.
Pilot plants design and construction
Life Cycle Assessment (LCA): environmental assessment of a particular product or process,
development of specific methodologies for industrial sectors (tailored assessments).
Ecoproducts and Ecoprocesses
Sediment characterization (surface water) and hydrogeological studies
MOST RELEVANT PROJECTS
1. ITACA (Research on Technologies for treatment, reuse and monitoring for future sustainability of water
treatment) INNPRONTA 2011. IPT-20111020.
2. URWASTECH (Innovative Urban Waste Treatment: a sustainable approach using hydrodynamic and
biological technologies) – European Project: LIFE+ 2010. 11-I-004 LIFE+.
3. ELVISUSTECH (End Life Vehicles: Innovative and Sustainable Technology for Achieving European
Directive Targets) – European Project: LIFE+ 2009. 10-I-017 LIFE+.
4. SENSOSEP (New technologies in sensors and ejectors to improve the solid waste separation) - Regional
Project: NUCLI ACC1O 2009, RD09-1-0046.
5. REPHATER (Electrochemical water treatment pilot plant in the dairy industry with phosphate recovery).
European Project: CIP-EIP-Eco-Innovation-2008, 238976.
6. ECOMETRE (Ecological Metal Recovery). European Project: CIP-EIP-Eco-Innovation-2008, 239037.
7. SEILA: New Technologies for an efficient, ecologic and intelligent washing system for the future textiles,
CENIT 2009. CEN20091005.
8. Viability study of the reuse of water coming from WWTP in the Vallès Occidental region for industrial
uses. Regional Project: AGAUR 2008. Ref: 2008ACOM00006.
41

9. Treatment and reuse of textile wastewater by means of Advanced Oxidation Processes. National project:
Ministerio de Industria, Turismo y Comercio; LIA Desarrollo experimental 2008. Ref: DEX-560510-2008-
31.
10. Investigation of alternative technologies for industrial wastewater treatment. Nacional Project: Ministerio
de Industria, Turismo y Comercio; LIA CT 2008. Ref: DEX-560620-2008-82.
11. Treatment and waste valorization from a pharmaceutical company. Industrial Project 2009.
12. Reutilization study of water coming from the WWTP in Terrassa for industrial uses. Industrial project with
the Catalan Water Agency (ACA). Ref: CTN0802456 2008.
13. BIOLEC: New advanced electrochemical technologies for the treatment of wastewater coming from
biodiesel industry. Autonomic project: VALTEC ACC1O 2009. VALTEC09-1-0024.
14. Reclamation and reuse of treated wastewater from a WWTP in the Vallès Occidental region for industrial
uses. Regional Project: AGAUR 2009. Ref: 2009ACOM00111.
15. 3R-FISH, LIFE+, January 2009. LIFE07 ENV/E/00814.
16. Research and development of new technologies for wastewater treatment in the textile industry.
Postdoctoral project 2007BP-B200005.
PUBLICATIONS
1. Jose Blanco, Francesc Torrades, Mertitxell de la Varga, Julia García-Montaño. Fenton and biological
Fenton coupled processes for textile wastewater treatment and reuse. Desalination 286 (2012) 394–399.
2. Conference: REPHATER: Elecrochemical water treatment pilot plant in a dairy industry with phosphate
recovery, CHEMPOR 2011, Lisboa, September 2011.
3. David Galí, Julia García-Montaño, Meritxell de la Varga, Electrochemical Advanced Processes to
biodiesel wastewater treatment (BIOLEC), Chempor 2011, Lisboa, September 2011, poster.
4. Julia García Montaño, Carlos Pérez Wait and Meritxell de la Varga, ECOMETRE: Ecologival metal
recycling. 12th Mediterranean Congress of Chemical Engineering, Barcelona, November 2011, poster.
5. José Blanco, Francesc Torrades, David Galí, Julia García-Montaño, MdelaVarga, Use of textile
wastewater for dyeing processes after photo-Fenton and coupled biological-photo-Fenton treatment. 12th
Mediterranean Congress of Chemical Engineering, Barcelona, November 2011, poster.
6. Conference: Remediation of textile wastewaters by means of Fenton and biological-Fenton coupled
processes. 6 th European Meeting on Chemical Industry and Environment, May 2010, Mechelen, Belgium,
7. Jose Blanco, Francesc Torrades, Julia García‐Montaño, María. Navarro, David Galí, Meritxell de la
Varga. Use of photo-Fenton reactions for textile wastewater treatment and reuse, 6 th European Meeting
on Chemical Industry and Environment, May 2010, Mechelen, Belgium, poster.
8. Conference: Electrochemical water treatment pilot plant in the dairy industry with phosphate recovery,
SMAGUA 2010, Zaragoza, 4 March 2010,
9. Conference: Reutilisation study of water from the Terrassa municipal Waste Water Treatment Plant for
industrial applications, Terrassa, Barcelona, 3 March 2009.
10. Conference: Viability study of the industrial reuse of water in Terrassa, Ecosessions, Environment
Sessions (Ecocity & Industry). Barcelona Fair, L’hospitalet de Llobregat. 28 May 2009.
11. Maria N. Abellan, David Galí, Mertixell DelaVarga, Julia García-Montaño, Miren Blanco, Amaia Martínez,
Arrate Marcaide. Regeneration of paper mill wastewater with Fenton and photo-Fenton processes.
INNOVAMED CONFERENCE, October 2009, Girona, poster.
12. José Blanco, Maria N. Abellan, David Galí, Meritxell DelaVarga, Julia García-Montaño, Francesc
Torrades. Fenton and biological-Fenton coupled processes for textile wastewater treatment and reuse.
INNOVAMED CONFERENCE, October 2009, Girona, poster.
42

RENEWABLE ENERGIES
Competency Compendium
Dr. David GUTIÉRREZ-TAUSTE
Manager Renewable Energies Division, R&D department
Email: dgutierrez@leitat.org
Equipments:
Other Facilities:
Sun simulator AM1.5G (AAA class 2x 2 cm 2 , B class up to 2 m 2 of irradiated area)
UV light sources
Metal halide light sources
J-V characterisation
I-V supply sources
UV-Vis-NIR spectrometer
Pyranometer and calibrated c-Si solar cells
Data acquisition equipment
Battery of different ageing chambers (climatic, UV-climatic, Xenotest, saline, etc.)
AutoLAB potentiostat / galvanostat
Multichannel VMP3 potentiostat / galvanostat
Glove box
Hydrothermal reactors (up to 20 bar, 350ºC), coupled to micro-gas chromatograph
CAD (CATIA), FEA tools, rapid prototyping
Ink/paste formulations and deposition techniques (ink-jet printing, screen printing, spraying, doctor
bladding, electrospinning)
Chemical laboratory
Physicochemical characterisation (ATR-FTIR, ICP-MS, HPLC, UV-Vis spectrophotometer,
Differential Scanning Calorimetry, Total Organic Carbon analyser, ionic chromatography, Karl
Fischer, contact angle, optical microscopy, conductivity, biodegradability, toxicity, perfilometer, etc.)
SPECIFIC RESEARCH INTERESTS
Design of innovative solar concentrators and tracking systems for photovoltaics.
Novel nanoarchitectures and manufacturing processes for organic/hybrid photovoltaics (Organic/Dye
Sensitized Solar Cells).
Seebeck/Peltier effects in renewable energy production (thermoelectricity).
Combined antireflection-cooling lenses for photovoltaics.
Innovative refrigeration concepts for photovoltaics.
Novel luminescent solar concentrators based on photoluminescence, down-shifting and up-conversion
phenomena for photovoltaics.
Clean hydrogen fuel-carrier production and Fuel Cell technologies
43

Ionic liquids as novel media for renewable energy production.
Novel forms of CO 2 capture and valorization.
PCM (Phase Change Materials) for energy storage.
Innovative refrigeration concepts based on thermoelectricity.
Integration of renewable energy power sources in specific applications.
Microbial Fuel Cells
Electrochemical Double Layer Supercapacitors
Li-ion and Li-air batteries
Examples of experiments:
Improving solar-to-electrical energy conversion efficiency of classical photovoltaics by means of backcoupling
cooling systems based on Phase Change Materials or Peltier cells. Performance studies
carried out upon simulated sunlight at different intensities.
Performance studies of home-made solar concentrators, tacking systems and luminescent solar
concentrators under simulated sunlight at different intensities.
Synthesis and characterization of materials for energy applications e.g. C-based electrodes for
supercapacitors or highly hydrophobic electrolytes for lithium battery technologies.
Design and construction of home-made prototypes for different applications in photovoltaics,
thermoelectricity or energy storage.
Design, development and optimization of novel concepts of PV modules, supercapacitors, Li-ion or Liair
energy storage technologies.
CO 2 capture and valorization in novel media (e.g. low-cost ionic liquids).
MOST RELEVANT PROJECTS
1. Improving efficiency of photovoltaic systems, co-financed By Caixa Terrassa.
2. EPHOCELL: Smart Light Collecting system for the efficiency enhancement of solar cells, NMP-2008-
2.6.1 and ENERGY 2008-10-1.2, FP7. Grant 227127.
3. ENERTEX: Energy harvesting from human body heat using thermoelectric modules. FIT-120000-2007-9.
4. SUPERCAP: Research and development of new supercapacitors based on double layer and pseudocapacitative
electrochemical effects. Co-financed by ACC1O and FEDER (RD 10-1-005).
5. LIQUION: Research on ionic liquid technologies for industrial applications. Co-financed by CDTI. CEN-
20101011.
6. Capture and valorization of CO 2 . Co-financed by Obra social Unnim Caixa Terrassa.
7. PHOTOFUTURE: Study and realization of new generation luminescent solar concentrators, Marie Curie
FP7 programme, grant agreement 226070 (host institution)
8. NANOTHERM: Tailoring electronic and phononic properties of nanomaterials: towards ideal
thermoelectricity, Consolider-Ingenio 2010.
9. NEXTEC: Themoelectric energy converters based on nanotechnology. NMP-2010-1.2-3, grant
agreement 263167.
10. ITACA: Development of technologies for the treatment, reutilization and control of future sustainable
water treatment. Innpronta 2011.
44

PUBLICATIONS
1. D. Gutiérrez-Tauste et. al. “New low-temperature preparation method of the TiO 2 porous photoelectrode
for dye-sensitized solar cells using UV irradiation”. Journal of Photochemistry and Photobiology A:
Chemistry 175 (2005) 165-171.
2. L. Aubouy et. al. Europium: Nature, Luminescence and Applications, Anales de la Real Sociedad
Española de Química 102 (2006) 40-45. Anales de la Real Sociedad Española de Química 102 (2006)
40-45.
3. D. Gutiérrez-Tauste et. al. “Hexafluorotitanate salts containing organic cations: use as a reaction medium
and precursor to the synthesis of titanium dioxide.” Chemical Communications (2007) 4659-4661.
4. D. Gutiérrez-Tauste et. al. “Low-temperature preparation route for nanocrystalline TiO 2 in multigram scale
using R 2 TiF 6 (R=BetH + , Cho + ) ionic liquid like precursor solutions: Application in Dye-Sensitized Solar
Cells”, HOPV conference 2009.
5. D. Gutiérrez-Tauste et. al. “EPHOCELL project: smart light collecting system for the efficiency
enhancement of solar cells”, HOPV conference 2010.
6. D. Gutiérrez-Tauste et. al. “Solar cell efficiency enhancement through down-shifting and up-converting
layers in the Ephocell project”, EUPVSEC conference 2010.
7. D. Gutiérrez-Tauste, C. Largeot, J.A. Sáez, D. Amantia, M. Faccini: ”Electrochemical Double Layer
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45

LEITAT TECHNOLOGICAL CENTER IS MEMBER OF
ACCEL - Agrupación para la Consecución de un Cielo Europeo Limpio
AEI TExtil – Agrupació d’Empreses Innovadores Tèxtils
AELAF – Asociación Española de Laboratorios de Fuego
AENEAS Aliança BioNanoMed - Association Catalunya for European NanoElectronics Activities
APPICE - Asociación Española de Pilas de Combustible
ARTEMIS ASEBIO – Industry Asociación Association Española de Bioempresas
ASERM – Asociación Española de Rapid Manufacturing
Asociación de Técnicos de la Industria Textil
ASTEC - Associació Catalana de Tecnologia
Biocat - Clúster biotecnológico y biomédico de Catalunya
CataloniaBio – Associació Catalana d’Empreses Biotecnològiques
Club EMAS - Associació d'empreses registrades EMAS a Catalunya
Cluster Marítimo Español
E2BA EuroLab – Energy España Efficient Building Association
E-GOLF European FEDIT - Centros
- Asociación Textile Tecnológicos Collectivities Europea
de
de Association España
Laboratorios de Fuego
FELAB – Asociación de entidades de Ensayo, Calibración y Análisis
EFFRA - European Factories of the Future Research Association
Genoma España – Fundación para la investigación genómica aplicada
Enterprise Europe Network
Groupe Grup Connect-EU Europeén / d’échange Automoción d’expériences sostenible Sur la Direction de la Recherche Textile
ERA-Net Grup Connect-EU ICT-AGRI / Catálisis (LEITAT Sostenible participa como observador dentro de este programa
europeo)
Grup Connect-EU / Energía
EU
Grup
PV
Connect-EU
Clusters
/ Factorías del futuro
EURACHEM Grup Connect-EU – Network / Materiales of Organitzations for Analytical Chemistry in Europe
Grup Connect-EU / Nanobio + Nanomed
Grup Connect-EU / Water.cat
IDESCAT - Cluster Català de l'Esport
NanoImpactNet
Oficina d’Acreditació d’Entitats Col·laboradores
Nanosafety
Oncocat – Red
Cluster
Catalana de Oncología
R+D+I REDMA Project – Red Euro-Action de Laboratorios Group y Entidades Association de Inspección Medioambiental
SECARTYS - Asociación Española para la Internacionalización de las Empresas de
Electrónica, Informática y Telecomunicaciones
STA - Sociedad de Técnicos de Automoción
TECNIO - Expertos en investigación aplicada y transferencia tecnológica de
Catalunya
EUROPEAN TECHNOLOGY PLATFORMS
European Technology Platform on Smart Systems Integration (EPoSS)
European Platform for Sports and Innovation (ÉPSI-eu)
European Technology Platform on Industrial Safety (ETPIS)
European Technology Platform on Advanced Engineering Materials and
Technologies (EuMat)
46

European Technology Platform for the future of textiles and clothing (NO
participamos directamente sino a través del Consejo Intertextil Español) (EURATEX)
In Vitro Testing Industria Platform (IVTIP)
European initiative for sustainable development by Nanotechnologies (NANOfutures)
Renewable Heating & Cooling European Technology Platform (RHC-ETP)
Rapid Manufacturing Platform (RM-Platform)
European Technology Platform for Sustainable Chemistry (Suschem)
Water Supply and Sanitation Technology Platform (WSSTP)
SPANISH TECHNOLOGY PLATFORMS
Plataforma Tecnológica Española de la Biomasa (BioPlat)
Plataforma Tecnológica Española de tecnologías para la Salud, El Bienestar y la
Cohesión Social (eVIA)
Food for Life – Spain (FFL-Spain)
Plataforma Tecnológica Española de Nanoelectrónica e Integración de Sistemas
Inteligentes (Genesis Red)
Plataforma Tecnológica Española de la Industria del Deporte (Inesport)
Plataforma Tecnológica Española de logística Integral (Logistop)
Plataforma Tecnológica Española de investigación en el ámbito de la fabricación
(Manufuture-E)
Plataforma Española de Nanomedicina (Nanomed)
Plataforma Tecnológica Tecnologica Española de Seguridad Envase y Embalaje Industrial (PACKNET) (PESI)
Plataforma Tecnológica Española del Agua (PTEA)
Plataforma Tecnológica Española de la Construcción (PTEC)
Plataforma Tecnológica Española de Hidrógeno y Pilas de Combustible (PTE-HPC)
Plataforma Tecnológica Marítima (PTEM)
Plataforma Tecnológica Española de la Pesca y la Acuicultura (PTEPA)
Plataforma Tecnológica del Hogar Digital (PTHD)
Plataforma Tecnológica para la Protección de la Costa y del Medio Marino (PT-
PROTECMA)
Plataforma Tecnológica Española para el Sector de Componentes de Automoción
(SERtec)
Plataforma Solar CONCENTRA (SOLAR CONCENTRA)
Plataforma Tecnológica Española de Química Sostenible (Suschem-E)
Plataforma de Mercados Biotecnológicos
Plataforma Tecnológica Textil Española
47

LEITAT – Technological Center
Phone. +34 93 788 23 00
Fax. +34 93 789 19 06
www.leitat.org
leitat@leitat.org