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E',tsP.a\A

E',tsP.a\A

ICAL CO. LTD.


GOmpfeCelt M i"ro"ry"tattine Cettutose is a partia y depotymerized

cellulose prepared by acid hydrolysis of purified wood pulp, nature's most

abundant polymer.

GOmpfeC€l@ products are widety used as key ingredient in

pharmaceutical and nutraceutical supplement applications, primarily as

binder/diluent/disintegrant in tablet and capsule formulations in both wet

granulation and direct compression processes.

COmpfeC€1"

products are used in cosmetics and food products as well.

The superior physical ch a racteristics, combined with its multiple functions make

it a logical tableting choice. In addition, Comprecel@ is particularly usefui in the

spheronisation of powders, facilitating the filling of two piece gelatin capsules.


ll Comprecel@ Applications and Functions

Drug

Binder

Filler

Disintegrant

Lubricant

Flow Aid

Food

Anticaking agent

Calories replacement

Fiber source

Absorbent

Extruded agent

Industry

Paving

Painter

Plastic

Thin Layer

Chromatography

In drug: That Comprecel@ Microcrystalline Cellulose focus on opportunities for orugs

as functions mentioned above is primarily tablets including direct

compression and wet granulation. lt is also used to prepare granules,

beadlets or minor involvement in capsules, suppositories etc.

In food: Comprecel@ Microcrystalline Cellulose can apply widely in food industries on

account of its excellent properties. For the purpose of anticaking, it has

become popular, such as shredded cheese and chinese herb granule.

In industry:

Scienceiftic technology always delivers innovative products. Applications of

button, painter, and even telephone tablet or treatment aid for ceramics

catalyst for natural gas make Comprecel@ M icrocrysta lline Cellulose an

optimum effects of result.


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Why Comprecel' producfs

ore your logicol choice

-

1 .Excellent compressibility

2.High dilution potential

3.Optimum range of particle size distribution

4.Low coefficient of friction

5.Good flowability

6.Fast d isinteg ration

7. B ind er-f ille r-d isinteg ra nt a multi-function excipient.

"**

Comprecel'

Formulolion A

Angle

Density

9/m

Mean Particle

Hardness

Disintegration

Dissolution

M101 39

0.28 50

11.0

21

84

M301 37

0.36 50

9.5

20

91

M 102 36

0.3'1 90

s.7

20

94

N/302 34

0.38 90

B.B

19

95

M200 33

0.38 170

8.2

19

95

Formulation A

1. Hydrochlorothiazide 459

2. Dicalcium phosphate dihydrate (unmilled) 909

3. Lactose (100M) 909

4. comprecel@ 75g

5. Disolcel@ 1g

6. Magnesaum Stearate 39

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