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ANNUAL REPORT 2012 - TiGenix

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7.5. SCIENTIFIC ADVISORY BOARD<br />

AND CLINICAL ADVISORS<br />

7.7.2. Shares and warrants held<br />

by executive management<br />

<strong>TiGenix</strong> SAU has appointed and closely works<br />

with two scientific advisory boards for the<br />

clinical development of the Cx601 and Cx611<br />

programs :<br />

- Gastroenterology advisory board : This<br />

board is assisting the clinical development<br />

of Cx601. The board is coordinated by Dr.<br />

Julian Panés (Spain) and is integrated by Dr.<br />

Jean-Frédéric Colombel (France), Dr. Walter<br />

Reinisch (Austria), Dr. Gert Van Assche<br />

(Belgium), Dr. Silvio Danese (Italy) and Dr.<br />

Daniel Baumgart (Germany).<br />

Please refer to section 13.7.7.<br />

7.7.3. <strong>TiGenix</strong> Stock option plan<br />

<strong>TiGenix</strong> created several warrants within the<br />

context of stock option plans for employees,<br />

consultants or directors of the Company, as<br />

well as to persons who in the scope of their<br />

professional activity have made themselves<br />

useful to the Company.<br />

For a description of the different stock option<br />

plans of <strong>TiGenix</strong>, see section 5.6.<br />

- Rheumatology advisory board : This board<br />

is assisting the clinical development of<br />

Cx611. The board is coordinated by Dr.<br />

José María Alvaro-Gracia (Spain) and<br />

is integrated by Dr. Victor Fernández-<br />

Taboada (Spain), Dr. Federico Díaz-<br />

González (Spain), Dr. Jesús Honorato<br />

(Spain), Dr. Peter C. Taylor (UK) and Dr.<br />

Georg A. Schett (Germany).<br />

7.6. REMUNERATION <strong>REPORT</strong><br />

Please refer to section 13.7.7.<br />

7.7. SHARES AND WARRANTS HELD<br />

BY DIRECTORS AND EXECUTIVE<br />

MANAGEMENT<br />

7.7.1. Shares and warrants held<br />

by independent and other<br />

non-executive directors<br />

Please refer to section 13.7.7.<br />

7.7.4. <strong>TiGenix</strong> SAU Equity Based<br />

Incentive Plans<br />

7.7.4.1. Summary of the Equity Based<br />

Incentive Plans<br />

Prior to the contribution of all shares of <strong>TiGenix</strong><br />

SAU (previously : Cellerix SA) to the Company<br />

on May 3, 2011 (the “Contribution”),<br />

<strong>TiGenix</strong> SAU had created two Equity Based<br />

Incentive Plans (“EBIPs”). The completion of<br />

the Contribution on May 3, 2011 triggered<br />

certain consequences outlined below<br />

which affect both EBIPs (section 7.7.4.2). A<br />

summary overview of some of the conditions<br />

of both EBIPs is given below. Note (24) to the<br />

consolidated financial statements, part of<br />

Section 11.5.4 contains a numerical summary<br />

of the options granted and outstanding as of<br />

December 31, <strong>2012</strong>.<br />

EBIP 2008<br />

An EBIP for the directors, managers and<br />

employees of <strong>TiGenix</strong> SAU was approved at<br />

the shareholders’ annual general meeting<br />

of <strong>TiGenix</strong> SAU held on November 22, 2007,<br />

95

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