Progressive Supranuclear Palsy

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Clinical Features of PSP Eyelid disorders: delay in lid opening, lid lag, repetitive blinking in response to flashlight stimulus (failure to habituate), blepharospasm Tonic head deviation opposite to direction of body rotation (vestibulocollic reflex) Inability to clap just three times (applause sign) Leigh RJ, Zee DS. Diagnosis of Central Disorders of Ocular Motility. Chpt 12: 598- 718. The Neurology of Eye Movements, Fourth Edition. Oxford University Press, NY, 2006.
Neuroimaging Figure 1: Sagittal T2-weighted MR in another patient with PSP shows the tectal plate is markedly thinned and atrophic. Courtesy Anne Osborn, MD.
Page 1 and 2: HARVARD MEDICAL SCHOOL DEPARTMENT O
Page 3 and 4: Supportive Criteria for Dx PSP Symm
Page 5: Clinical Features of PSP Smooth eye
Page 9: Figure 3. PET in a patient with PSP
Page 12 and 13: Pathology Figure 6: PSP-the-globose
Page 17 and 18: Tauopathies: Clinical Diseases Alzh
Page 19 and 20: Richardson JC, Steele J, Oszewski J

Progressive Supranuclear Palsy

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