CEDARLANE www.cedarlanelabs.com - Tebu-Bio
CEDARLANE www.cedarlanelabs.com - Tebu-Bio
CEDARLANE www.cedarlanelabs.com - Tebu-Bio
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Specificity/Species Application(s) Format Size Cat#<br />
CD59/Human F Purified 250 ug CL7673AP<br />
clone: 1F5, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL7673B<br />
Detects human CD59 (protectin). CD59 blocks MAC FITC 100 ug CL7673F<br />
formation by interfering with C9 membrane insertion PE 50 ug CL7673PE<br />
and polymerization.<br />
DAF (CD55)/Human F, E, WB Purified 250 ug CL7540AP<br />
clone: RIKO-3, isotype: Hamster IgG <strong>Bio</strong>tin 100 ug CL7540B<br />
Detects human DAF (decay accelerating factor) FITC 100 ug CL7540F<br />
which inhibits autologous C3 activation. PE 50 ug CL7540PE<br />
Crry/Rat F, IHC (F) Purified 250 ug CL064AP<br />
clone: 5I2, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL064B<br />
Detects rat Crry which is a rat specific <strong>com</strong>plementregulator<br />
which can inhibit both classical and<br />
alternative C’ activation.<br />
FITC 100 ug CL064F<br />
Antibodies to Complement Receptors<br />
Specificity/Species Application(s) Format Size Cat#<br />
C3aR/Rat F, IHC (F) Purified 250 ug CL031AP<br />
clone: 74, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL031B<br />
Detects rat C3a Receptor. FITC 100 ug CL031F<br />
PE 50 ug CL031PE<br />
C5aR/Mouse F, IF, blocking Purified 250 ug CL7588AP<br />
clone: 20/70, isotype: Rat IgG2b <strong>Bio</strong>tin 100 ug CL7588B<br />
Detects mouse C5a Receptor (CD88). FITC 100 ug CL7588F<br />
Low Endo. 500 ug CL7588LE<br />
No Azide 1 mg CL7588NA<br />
PE 50 ug CL7588PE<br />
C5aR/Human F, IHC (F), blocking Purified 250 ug CL7688AP<br />
clone: 8D6, isotype: Rat IgG2a <strong>Bio</strong>tin 100 ug CL7688B<br />
Detects human C5a Receptor (CD88). FITC 100 ug CL7688F<br />
PE 50 ug CL7688PE<br />
gC1q-R/Human F, WB, E Ascites 0.5 ml CL7601A<br />
clone: 60.11, isotype: Mouse IgG1 Purified 250 ug CL7601AP<br />
Detects the human gC1q-R membrane protein. Epitope <strong>Bio</strong>tin 100 ug CL7601B<br />
for this antibody is one of the C1q binding sites. FITC 100 ug CL7601F<br />
gC1q-R/Human F, WB, E Ascites 0.5 ml CL7602A<br />
clone: 74.5.2, isotype: Mouse IgG1 Purified 250 ug CL7602AP<br />
Detects the human gC1q-R membrane protein. Epitope PE 50 ug CL7602PE<br />
for this antibody is the binding site for High Molecular<br />
Kininogen (HK).<br />
Complement<br />
Rabbit and Guinea Pig Complement<br />
& Antibodies to...<br />
Complement Components,<br />
Regulators and Receptors<br />
For over 50 years, <strong>CEDARLANE</strong> ® has been producing<br />
<strong>com</strong>plement. Special processing techniques are used to<br />
yield products with high <strong>com</strong>plement activity and low<br />
background cytotoxicity.<br />
<strong>CEDARLANE</strong><br />
<strong>www</strong>.<strong>cedarlanelabs</strong>.<strong>com</strong><br />
ISO 9001:2000 and ISO 13485:2003 registered <strong>com</strong>pany.<br />
Special formats,<br />
Bulk quantities<br />
and<br />
Lot reserves<br />
offered.<br />
LEGEND for APPLICATIONS:<br />
C = Cyrostat Sections,<br />
E= ELISA, F = Flow Cytometry,<br />
IHC = Immunohistochemistry,<br />
IF = Immunofluorescense,<br />
IP = Immunoprecipitation,<br />
R = RIA,<br />
WB = Western Blotting<br />
Complement 2008.indd 1 12/8/2008 12:02:29 PM<br />
®
Complement<br />
Rabbit Complement<br />
Product Application(s) Format Size Cat.#<br />
Standard HLA-ABC tissue typing frozen 5x5ml CL3005<br />
Rabbit Complement frozen 100ml CL3010<br />
lyophilized 25x1ml CL3111<br />
lyophilized 10x2ml CL3112<br />
lyophilized 5x5ml CL3115<br />
lyophilized 5x20ml CL3120<br />
Low-Tox®-H HLA-DR tissue typing frozen 2x5ml CL3305<br />
Rabbit Complement frozen 100ml CL3310<br />
lyophilized 10x1ml CL3331<br />
lyophilized 2x5ml CL3335<br />
Low-Tox®-M Cytotoxicity assays using lyophilized 5x1ml CL3051<br />
Rabbit Complement MOUSE lymphocytes<br />
Low-Tox®-R Cytotoxicity assays using lyophilized 3x1ml CL3061<br />
Rabbit Complement RAT lymphocytes<br />
Rabbit Complement Cytotoxicity Assays using lyophilized 10x1ml CL3221<br />
MA monoclonal antibodies lyophilized 5x5ml CL3225<br />
to Human lymphocytes<br />
Baby Rabbit Cytotoxicity assays lyophilized 10x1ml CL3441<br />
Complement lyophilized 2ml CL3442<br />
Baby Rabbit Bacteriocidal, cytotoxicity frozen 1ml CL3441-S<br />
Complement and depletion/purging frozen 100ml CL3441-<br />
Tissue Culture Grade assays especially in cancer, S100<br />
(Low Endotoxin) transplantation studies,<br />
and vaccine quality control<br />
and manufacturing<br />
Guinea Pig Complement<br />
<strong>CEDARLANE</strong> ® ’s Baby Rabbit Complement<br />
- Tissue Culture Grade is aseptically collected<br />
from 3-4 week old rabbits. The pooled sera<br />
is then thoroughly tested to ensure that the<br />
<strong>com</strong>plement is bacteria-free, mycoplasma-free,<br />
virus-free and low in endotoxin.<br />
Product Application(s) Format Size Cat.#<br />
Standard Haemolytic plaque assays/ lyophilized 5x5ml CL5000<br />
Guinea Pig Complement Complement fixation assays lyophilized 5x1ml CL5000-1<br />
Hemo-Lo sRBC assays lyophilized 5x5ml CL4555<br />
Guinea Pig Complement<br />
Low-Tox® Cytotoxicity assays/ lyophilized 5x1ml CL4051<br />
Guinea Pig Complement plaque assays<br />
Antibodies to Complement Components<br />
Specificity/Species Application(s) Format Size Cat#<br />
C1q/Human F, IF, C, WB, E Purified 250 ug CL7611AP<br />
clone: MhC5B9, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL7611B<br />
Detects bound C1q but not unbound form. FITC 100 ug CL7611F<br />
PE 50 ug CL7611PE<br />
C1q/Mouse F, IF, C, WB, E Purified 250 ug CL7501AP<br />
clone: RmC7H8, isotype: Rat IgG1 <strong>Bio</strong>tin 100 ug CL7501B<br />
FITC 100 ug CL7501F<br />
PE 50 ug CL7501PE<br />
C3/Human/ Mouse F, E Purified 250 ug CL7631AP<br />
clone: 6C9, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL7631B<br />
Detects human and mouse C3/C3b/iC3b but not C3dg. FITC 100 ug CL7631F<br />
PE 50 ug CL7631PE<br />
C3/Human/ Mouse Purified 250 ug CL7632AP<br />
clone: 10C7, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL7632B<br />
CL7631AP (clone: 6C9) and CL7632AP (clone: 10C7) FITC 100 ug CL7632F<br />
recognize different epitopes of the C3/C3b/iC3b<br />
molecule and do not cross-<strong>com</strong>pete.<br />
PE 50 ug CL7632PE<br />
C3/Mouse F, IF, C, WB, E Purified 250 ug CL7503AP<br />
clone: RmC11H9, isotype: Rat IgG2a Purified 500 ug CL7503AP-2<br />
Detects mouse C3/C3b/iC3b and C3dg. <strong>Bio</strong>tin 100 ug CL7503B<br />
FITC 100 ug CL7503F<br />
No Azide 1 mg CL7503NA<br />
PE 50 ug CL7503PE<br />
C3a/Human pAb Chicken IgY WB, E Aff. Pur. 200 ug CL2503AP<br />
Detects human C3a (as well as C3). HRPO 100 ug CL2503HP<br />
C4/Mouse F, IF, C, WB, E Purified 250 ug CL7504AP<br />
clone: RmC16D2, isotype: Rat IgG2a Purified 500 ug CL7504AP-2<br />
Detects mouse C4 as well as C4b and C4d. <strong>Bio</strong>tin 100 ug CL7504B<br />
FITC 100 ug CL7504F<br />
No Azide 1 mg CL7504NA<br />
C4b/Human pAb Chicken IgY F, WB, E Purified 500 ug CL2154AP<br />
C5/Mouse pAb Rabbit Ig C, WB Ig Fraction 100 ug CL7505<br />
C6/Mouse pAb Rabbit Ig C, WB Ig Fraction 100 ug CL7506<br />
Antibodies to Complement Regulators<br />
Specificity/Species Application(s) Format Size Cat#<br />
C1 Inhibitor/Human E Purified 5 mg CL20023A<br />
Polyclonal Goat Aff. Pur. 0.5 mg CL20023AP<br />
Detects C1 Inhibitor (also called C1 Inactivator). HRPO 0.2 mg CL20023HP<br />
Factor H/Human F, E, IP, WB Purified 250 ug CL7672AP<br />
clone: OX-24, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL7672B<br />
Detects Factor H (cofactor for Factor for C3b cleavage). FITC 100 ug CL7672F<br />
Factor I/Human E, IP, WB, R Purified 250 ug CL7671AP<br />
clone: OX-21, isotype: Mouse IgG1 <strong>Bio</strong>tin 100 ug CL7671B<br />
Detects human Factor I (C3b inactivator). FITC 100 ug CL7671F<br />
Complement 2008.indd 2 12/8/2008 12:02:33 PM