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Midterm 1 KEY MC Answers 1. B 2. B 3. A 4. D 5. A 6. D 7. C 8. A 9 ...

Midterm 1 KEY MC Answers 1. B 2. B 3. A 4. D 5. A 6. D 7. C 8. A 9 ...

Midterm 1 KEY MC Answers 1. B 2. B 3. A 4. D 5. A 6. D 7. C 8. A 9

Midterm 1 KEYMC Answers1. B2. B3. A4. D5. A6. D7. C8. A9. B10. C11. C12. D13. B14. C15. A16. A17. D18. C19. C20. DDefinitions1. Old view of genome; information travels from DNA through RNA to protein. One gene, oneprotein.2. Proportion of phenotypic variation in a population attributable to genetic variation amongindividuals.3. Logarithm of Odds. Statistical test for linkage analysis; score of 3.0+ evidence for linkage.4. Single nucleotide polymorphism; found in at least 1% of general population. Usually only 2alleles. Used as genetic markers.5. Same structure and function of genes across species.6. Technique to make GMO with (usually temporary) reduced expression of one or more genes;genetic silencing.Short Answers1. QTL analysis uses molecular genetics to ID multiple genes contributing to a trait. With nonhumanmodels you can induce polymorphisms to study, have greater control, different ethics,etc. Animals’ results useful from subcellular level up to behaviour. Techniques: knockout,knockdown, knockin, inbred strains, crosses; all are feasible with non-humans (but not humans).Issue of synteny homology.

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