Cover Introduction ProSure Clinical Studies ... - Abbott Nutrition

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Cover Introduction ProSure Clinical Studies ... - Abbott Nutrition

Weight stabilisation is associated with improved survival duration and quality of lifein unresectable pancreatic cancerCoverDavidson W, Ash S, Capra S, Bauer J Clin Nutr. 2004;23:239-247IntroductionProSureClinical StudiesSupportingPublicationsDavidson and colleagues performed a post hoc analysis of data from107 patients who were enrolled in the Fearon 2003 trial. Patients wereincluded in the post hoc analysis if weight data was available for bothbaseline and week 8.ObjectiveTo examine whether weight stabilization was associated withimproved survival and QoL and to identify determinants of weightstabilization.Study Design• Study Population: Pancreatic (n = 107)• Length of Study: 8 weeks• Intervention: 2 servings/day ProSure (240 mL/serving) orisocaloric, isonitrogenous controlOutcomes• Patients with weight stabilization survived longer from baseline (logrank test 5.53, P = 0.019). They also reported higher QoL scores(P = 0.037) and a greater mean energy intake (P < 0.001) at week 8than those who continued to lose weight.Study ConclusionsWeight stabilization over an 8 week period in weight-losing patientswith unresectable pancreatic cancer was associated with improvedsurvival duration and QoL.EPA -eicosapentaenoic acid

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