Scoring Matrices

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Overview of Presentation• What are scoring matrices?• Some rudimentary scoring matrices• More advanced scoring matrices– PAM– BLOSUM• Advantages of BLOSUM over PAM

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Overview of Presentation• What are scoring matrices?• Some rudimentary scoring matrices• More advanced scoring matrices– PAM– BLOSUM• Advantages of BLOSUM over PAM

What are <strong>Scoring</strong> <strong>Matrices</strong>?• 20x20 matrix.– Each row and column corresponds to anamino acid• Chart of “similarity” between amino acids

Page 1: Scoring MatricesThe Arrays Used to
Page 5 and 6: Uses of Scoring Matrices• Used in
Page 7 and 8: Genetic Code Matrix• Looks at the
Page 9 and 10: Making PAM Matrices• To Create a
Page 11 and 12: BLOSUM Matrices• Developed by Ste
Page 13 and 14: BLOSUM Matrices - Clustering• Wha
Page 15 and 16: Summary• The two major sets of sc

Scoring Matrices

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