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Objectives OTC/RX/Herbal Background RX/OTC vs ... - sowega ahec

Objectives OTC/RX/Herbal Background RX/OTC vs ... - sowega ahec

Objectives OTC/RX/Herbal Background RX/OTC vs ... - sowega

ObjectivesThe Impact of OTC and HerbalSupplements with PrescriptionMedicationsMichael J. Schuh, BS, PharmD, MBAAssistant Professor of PharmacyMayo College of MedicineReview of over-thethe-counter (OTC),prescription (Rx), and herbal supplementbackgroundsDiscuss common classes of OTCmedications as to adverse reactions anddrug interactions with Rx medications andherbal supplementsDiscuss common herbals and theirproperties that can interact with RxmedicationsOTC/RX/Herbal BackgroundOTC and herbal supplements have theirown adverse reactions just like RxmedicationsOTC and herbal supplements interact withRx medications and with each otherHerbal supplements are not regulated bythe FDA as OTC and Rx medications areCenter for Drug Evaluation andResearch (CDER)A part of the U.S. Food and DrugAdministration (FDA)The nation’s “watchdog” for consumersregarding OTC, Rx medications and somecosmetics/toiletries that are classified asdrugs such toothpaste, antiperspirants,dandruff shampoos, sunscreenshttp://www.fda.gov/fdac/special/testtubetopatient/cder.htmlRX/OTC vs. HerbalSupplementsCenter for Drug Evaluation and Research(CDER) Rx/OTC Statement:Drug companies seeking to sell a drug inthe United States must first test it…. . Thecompany then sends CDER the evidencefrom these tests to prove the drug is safeand effective for its intended use…. Herbalsupplement companies do not!Mechanisms of OTC and HerbalImpact on Rx MedicationsDrug interactions:– P-450 hepatic enzyme inhibition or induction(ex. clopidogrel/omeprazole-OTC)– Displacement from blood proteins (ex.warfarin/miconazole-vaginal)– Receptor site agonist/antagonist (ex.SSRI’s/St. John’s s Wort)http://www.fda.gov/fdac/special/testtubetopatient/cder.htmlDiPiro, et al. Pharmacotherapy: A physiological Approachwww.thompsonhc.com, accessed 4/7/2010

Objectives Applied-Means Practice ABA continued ... - sowega ahec
4/17/2012 1 Disclosures Objectives - sowega ahec