Info - Valley Vet Supply

abcdPrescription strength efficacy against today’s most prevalent pathogens.

Cost effective - highly affordab91% of sub-clinical intramammary infectionsat calving are gram-positive.Prevalence ofIMI pathogens at calving 1Multi-site, multi-herd field study involving11 herds and 1,028 cows. National MastitisCouncil, 2007. 1Coagulase-negative Staphylococcus spp. (CNS) ......51%Bacillus spp. .........................................16%Streptococcus uberis ...................................8%Enterococcus spp. ......................................7%Aerococcus spp. .......................................5%Staph. aureus. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2%Other .................................................2%E. coli .................................................5%Enterobacter spp. ......................................2%Klebsiella spp. .........................................1%Yeast .................................................1%Ampicillin (the active form of Hetacin-K) hasdemonstrated excellent activity againstenvironmental Streptococcus spp. 2, 3The majority of clinical cases of gram-positive mastitis, regardless of farm size,are caused by environmental streps. 4Small(

leHetacin-K is about half the price of prescription cephalosporin treatments.Prescription strengthefficacy against…Streptococcus dysgalactiaeStreptococcus agalactiaeStaphylococcus aureusandEscherichia coliHetacin-K was the first mastitis tube labeled andapproved for treatment of E. coli in dairy cattle!Flexible label provides increased convenienceEfficient Treatment ManagementOne infusionevery 24 hoursLabeled for upto three days oftreatment72-hourmilk withhold10-dayslaughterwithdrawalHetacin-K should not be used in animals that are found to be hypersensitive to theproduct, penicillin, or cephalosporin.

Opti-Sert® makes milk. partialinsertion accuratesusceptible strains of Streptococcusandagalactiae,easyStreptococcusdysgalactiae, Staphylococcus aureus and Escherichia coli.Partial insertion is proven to reduce newmastitis infections by up to 50 percent. 5Partial insertion …• helps prevent pushing harmfulsurface bacteria, includingMycoplasma, into teat canal• reduces the risk of teat canaland keratin plug damage• allows antibiotic contact withteat-canal infectionsNADA 55-054, Approved by FDAHetacin-K®(hetacillin potassium)Intramammary InfusionFor lactating cows onlyCaution: Federal law restricts this drug to use by or on the order of alicensed veterinarian.Description: Hetacin-K (hetacillin potassium) is a broad-spectrumagent which provides bactericidal activity against a wide range ofcommon gram-positive and gram-negative bacteria. It is derivedfrom 6-aminopenicillanic acid and is chemically related toampicillin.Each 10 mL disposable syringe contains hetacillin potassiumequivalent to 62.5 mg ampicillin activity in a stable peanut oil gel.This product was manufactured by a non-sterilizing process.Action: Hetacillin provides bactericidal levels of the active antibiotic,ampicillin. In vitro studies have demonstrated susceptibility of thefollowing organisms to ampicillin: Streptococcus agalactiae,Streptococcus dysgalactiae, Staphylococcus aureus and Escherichiacoli.Indications: For the treatment of acute, chronic or subclinicalbovine mastitis. Hetacin-K (hetacillin potassium) forIntramammary Infusion should be used at the first signs ofinflammation or at the first indication of any alteration in the milk.Subclinical infections should be treated immediately upondetermining, by C.M.T. or other tests, that the leucocyte count iselevated, or that a susceptible pathogen has been cultured from theHetacin-K for Intramammary Infusion has been shown to beefficacious in the treatment of mastitis in lactating cows caused byPolycillin® (ampicillin) SusceptibilityTest Discs, 10 mcg, should beused to estimate the in vitro susceptibility of bacteria to hetacillin.Dosage and Administration: Infuse the entire contents of onesyringe (10 mL) into each infected quarter. Repeat at 24-hourintervals until a maximum of three treatments has been given.If definite improvement is not noted within 48 hours after treatment,the causal organism should be further investigated.NADA 55-054, ApprovedPartialbyinsertionFDAHetacin-K®(hetacillin potassium)Intramammary InfusionFor lactating cows onlyabcdFull insertionCaution: Federal law restricts this drug to use by or on the order of alicensed veterinarian.Description: Hetacin-K (hetacillin potassium) is a broad-spectrumagent which provides bactericidal activity against a wide range ofcommon gram-positive and gram-negative bacteria. It is derivedfrom 6-aminopenicillanic acid and is chemically related toampicillin.1. Lago A., Godden S., Bey R., Leslie K., Dingwell R., Each Ruegg 10 mL P.L. disposable Prevalence syringe and Etiology containsof hetacillin Subclinical potassiumIntramammary Infections in Fresh Cows. 47th Annual equivalent Meeting to 62.5 of the mgNational ampicillin Mastitis activityCouncil; in a stable 2008 peanut Jan oil gel.20-23; New Orleans, Louisiana.This product was manufactured by a non-sterilizing process.2. Rossitto P.V., Ruiz L., KIkuchi Y., Glenn K., Luiz K., Action: Watts Hetacillin J.L., Cullor provides J.S. Antibiotic bactericidal Susceptibility levels of the Patterns active antibiotic,for Environmental Streptococci Isolated from Bovine ampicillin. Mastitis Inin vitro Central studies California have demonstrated Dairies. J. Dairy susceptibility Sci. of thefollowing organisms to ampicillin: Streptococcus agalactiae,85:132-138.Streptococcus dysgalactiae, Staphylococcus aureus and Escherichia3. Makovec J.A., Ruegg P.L. Antimicrobial resistance coli. of bacteria isolated from dairy cow milk samples submittedfor bacterial culture: 8,905 samples (19944-2001). Indications: For JAVMA, the treatment June 2003, of222:(11)1582-1589.acute, chronic or subclinical4. USDA National Animal Health Monitoring System bovine (NAHMA) mastitis. “Dairy Hetacin-K 2007.” (hetacillin potassium) for5. Boddie, R. L., Nickerson, S.C., Sutherland, S.F. “New Intramammary design of Infusion mastitis tubes shouldreduces be usedinfection.” at the firstHoard’ssigns ofDairyman, August 1989, 134:(13)579. inflammation or at the first indication of any alteration in the milk.Subclinical infections should be treated immediately upondetermining, by C.M.T. or other tests, that the leucocyte count iselevated, or that a susceptible pathogen has been cultured from themilk.Hetacin-K for Intramammary Infusion has been shown to beefficacious in the treatment of mastitis in lactating cows caused bysusceptible strains of Streptococcus agalactiae, Streptococcusdysgalactiae, Staphylococcus aureus and Escherichia coli.Polycillin® (ampicillin) SusceptibilityTest Discs, 10 mcg, should beabcdused to estimate the in vitro susceptibility of bacteria to hetacillin.Dosage and Administration: Infuse the entire contents of onesyringe (10 mL) into each infected quarter. Repeat at 24-hourAll product names are trademarks or registered intervals trademarks until a maximum of their respective of three treatments holders. has been given.© 2010 Boehringer Ingelheim Vetmedica, IfInc. definite All rights improvement reserved. is not noted within 48 hours after treatment,BIVI L0546D 09/10the causal organism should be further investigated.NADA 55-054, Approved by FDAHetacin-K®abcdWash the udder and teats thoroughly with warm water containing asuitable dairy antiseptic and dry, preferably using individual papertowels. Carefully scrub the teat end and orifice with 70% alcohol,NADA 55-054, Approved by FDAusing a separate swab for each teat. Allow to dry.Hetacin-K (hetacillin potassium) is packaged with the Opti-Sert®Hetacin-K®Protective Cap.abcd(hetacillin For partial insertion:Twist potassium) off upper portion of the Opti-SertIntramammary Protective Cap to expose Infusion 3–4 mm of the syringe tip.Forlactating full insertion: cows Remove only protective cap to expose the full length ofthe syringe tip.Caution: Insert syringe Federal tip into law restricts the teat canal this drug andto expel use the by or entire on the contents order of ofalicensed one syringe veterinarian. into each infected quarter. Withdraw the syringe andDescription: gently massage Hetacin-K the quarter (hetacillin to distribute potassium) the medication. is a broad-spectrumagent Do notwhich infuseprovides contentsbactericidal of the mastitis activity syringe against intoathe wide teatrange canalofifcommon the Opti-Sert gram-positive Protective Cap andis gram-negative broken or damaged. bacteria. It is derivedfrom Warning: 6-aminopenicillanic Milk that has been acidtaken and is from chemically animalsrelated duringtotreatmentampicillin. and for 72 hours (6 milkings) after the latest treatment must not beEach used 10 formL food. disposable syringe contains hetacillin potassiumequivalent Treated animals to 62.5 must mgnot ampicillin be slaughtered activity infor afood stable until peanut 10 days oil gel. afterThis the latest product treatment. was manufactured by a non-sterilizing process.Action: Precautions: Hetacillin Because provides it is abactericidal derivative of levels 6-aminopenicillanic of the active antibiotic, acid,Hetacin-K ampicillin. has In vitro the potential studies have for producing demonstrated allergic susceptibility reactions. Such of thefollowing reactions are organisms rare; however, to ampicillin: shouldStreptococcus they occur, treatment agalactiae, should bediscontinued Streptococcusand dysgalactiae, the subject Staphylococcus treated with antihistamines, aureus and Escherichia pressoramines, coli. such as epinephrine or corticosteroids.Indications: The drug does For not the resist treatment destruction of acute, by penicillinase chronic or subclinical and, hence,bovine is not effective mastitis. against Hetacin-K strains (hetacillin of staphylococcus potassium) resistant for toIntramammary penicillin G. Infusion should be used at the first signs ofStorage:inflammationStoreoratatcontrolledthe first indicationroom temperatureof any alteration15 - 30°Cin(59the-milk.86°F).Subclinical infections should be treated immediately uponHow determining, Supplied: byHetacin-K C.M.T. or other (hetacillin tests, potassium) that the leucocyte Intramammary count isInfusion elevated, isorsupplied that a susceptible as 10 mL syringes pathogencontaining has been 62.5 cultured mg from ampi-thcillinmilk. activity per syringe. One display carton contains 12 syringes.NDC Hetacin-K 0010-4719-01 for Intramammary 10 mL syringe Infusion has been shown to beOpti-Sert efficacious isin a registered the treatment trademark of mastitis of Wyeth in lactating LLC - used cows under caused license. byHetacin-K susceptibleisstrains a registered of Streptococcus trademark of agalactiae, Boehringer Streptococcus IngelheimVetmedica, dysgalactiae, Inc. Staphylococcus aureus and Escherichia coli.Polycillin® © 2010 Boehringer (ampicillin) Ingelheim SusceptibilityTest Vetmedica, Discs, Inc. All 10Rights mcg, Reserved. should be11250 used to estimate the in vitro susceptibility of bacteria to hetacillin. D4340AManufactured Dosage and Administration: for: Infuse the entire contents of onesyringe Boehringer (10 mL) Ingelheim into each Vetmedica, infected quarter. Inc. Repeat at 24-hourSt. intervals Joseph, until MOa 64506 maximum U.S.A. of three treatments has been given.If definite improvement is not noted within 48 hours after treatment,the causal organism should be further investigated.Wash the udder and teats thoroughly with warm water containing asuitable dairy antiseptic and dry, preferably using individual papertowels. Carefully scrub the teat end and orifice with 70% alcohol,NADA 55-054, Approved by FDAusing a separate swab for each teat. Allow to dry.Hetacin-K (hetacillin potassium) is packaged with the Opti-Sert®Hetacin-K®Protective Cap.abcd(hetacillin For partial insertion:Twist potassium) off upper portion of the Opti-SertIntramammary Protective Cap to expose Infusion 3–4 mm of the syringe tip.Forlactating full insertion: cows Remove only protective cap to expose the full length ofthe syringe tip.Insert Caution: syringe Federal tip into law restricts the teat canal this drug andto expel use the by or entire on the contents order of ofaone licensed syringe veterinarian. into each infected quarter. Withdraw the syringe andDescription: gently massage Hetacin-K the quarter (hetacillin to distribute potassium) the medication. is a broad-spectrumagent Do notwhich infuseprovides contentsbactericidal of the mastitis activity syringe against intoathe wide teatrange canalofifcommon the Opti-Sert gram-positive Protective Cap andis gram-negative broken or damaged. bacteria. It is derivedfrom Warning: 6-aminopenicillanic Milk that has been acidtaken and is from chemically animalsrelated duringtotreatmentampicillin. and for 72 hours (6 milkings) after the latest treatment must not beused Each 10 for mL food. disposable syringe contains hetacillin potassiumTreated equivalent animals to 62.5 must mgnot ampicillin be slaughtered activity in for afood stable until peanut 10 days oil gel. afterthe Thislatest product treatment. was manufactured by a non-sterilizing process.Precautions: Action: Hetacillin Because provides it is abactericidal derivative of levels 6-aminopenicillanic of the active antibiotic, acid,ampicillin. Hetacin-K has In vitro the potential studies have for producing demonstrated allergic susceptibility reactions. Such of thefollowing reactions are organisms rare; however, to ampicillin: shouldStreptococcus they occur, treatment agalactiae, should bediscontinued Streptococcusand dysgalactiae, the subject Staphylococcus treated with antihistamines, aureus and Escherichia pressoramines, coli. such as epinephrine or corticosteroids.Indications: The drug does For not the resist treatment destruction of acute, by penicillinase chronic or subclinical and, hence,is bovine not effective mastitis. against Hetacin-K strains (hetacillin of staphylococcus potassium) resistant for toIntramammary penicillin G. Infusion should be used at the first signs ofStorage:inflammationStoreoratatcontrolledthe first indicationroom temperatureof any alteration15 - 30°Cin(59the-milk.86°F).Subclinical infections should be treated immediately uponHow determining, Supplied: byHetacin-K C.M.T. or other (hetacillin tests, potassium) that the leucocyte Intramammary count isInfusion elevated, isorsupplied that a susceptible as 10 mL syringes pathogencontaining has been 62.5 cultured mg from ampi-thcillinmilk. activity per syringe. One display carton contains 12 syringes.NDC Hetacin-K 0010-4719-01 for Intramammary 10 mL syringe Infusion has been shown to beOpti-Sert efficacious isin a registered the treatment trademark of mastitis of Wyeth in lactating LLC - used cows under caused license. byHetacin-K susceptibleisstrains a registered of Streptococcus trademark of agalactiae, Boehringer Streptococcus IngelheimVetmedica, dysgalactiae, Inc. Staphylococcus aureus and Escherichia coli.Polycillin® © 2010 Boehringer (ampicillin) Ingelheim SusceptibilityTest Vetmedica, Discs, Inc. All 10Rights mcg, should Reserved. beused 11250to estimate the in vitro susceptibility of bacteria to hetacillin. D4340AManufactured Dosage and Administration: for: Infuse the entire contents of onesyringe Boehringer (10 mL) Ingelheim into each Vetmedica, infected quarter. Inc. Repeat at 24-hourintervals St. Joseph, until MOa 64506 maximum U.S.A. of three treatments has been given.If definite improvement is not noted within 48 hours after treatment,the causal organism should be further investigated.Wash the udder and teats thoroughly with warm water containing asuitable dairy antiseptic and dry, preferably using individual papertowels. Carefully scrub the teat end and orifice with 70% alcohol,using a separate swab for each teat. Allow to dry.stuHPFPFtIogDtWauTtPHrdaTipSHIcNOHV©1MBSstuHPFPFtIogDtWauTtPHrdaTipSHIcNOHV©1MBS