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Excellence Everywhere - National University of Ireland, Galway

Excellence Everywhere - National University of Ireland, Galway

Martin, Vivien. Managing

Martin, Vivien. Managing Projects in Health and SocialCare. London: Routledge, 2002.Portny, Stanley E. Project Management for Dummies.Hoboken, NJ: Wiley Publishing, 2000.Project Management Institute. Guide to the ProjectManagement Body of Knowledge. Newtown Square, PA:Project Management Institute, 2000.Sindermann, Carl J. Winning the Games Scientists Play.Cambridge, MA: Perseus Book Group, 2001.Usherwood, Tim. Introduction to Project Management inHealth Research: A Guide for New Researchers. Bristol,PA: Open University Press, 1996.OnlineAustin, Jim. “Management in the Lab.” ScienceCareers.org(September 13, 2003), http://sciencecareers.sciencemag.org/career_development/previous_issues/articles/1890__1/management_in_the_lab.Austin, Rob. “Project Management and Discovery.”ScienceCareers.org (September 13, 2003), http://sciencecareers.sciencemag.org/career_development/previous_issues/articles/1890__1/project_management_and_discovery.Billows, Dick. Work Breakdown Structure. 4PM ProjectManagement Certification and Training. http://www.4pm.com/articles/work_breakdown_structure.htm.Portny, Stanley E., and Jim Austin. “Project Managementfor Scientists.” ScienceCareers.org (July 12, 2002),http://sciencecareers.sciencemag.org/career_development/previous_issues/articles/1750/project_management_for_scientists.Portny, Stanley E. “Project Management in an UncertainEnvironment.” ScienceCareers.org (August 23, 2002),http://sciencecareers.sciencemag.org/career_development/previous_issues/articles/1820/project_management_in_an_uncertain_environment.NICEF/ UNDP/ World Bank/ WHO Special Programmefor Research and Training in Tropical Diseases (TDR).Effective Project Planning and Evaluation in BiomedicalResearch (Training Manual). Geneva, Switzerland: WorldHealth Organization, 2005.Effective project planning and evaluation inbiomedical research, a training manual and step bystep guide to project management from WHO/TDRhttp://www.who.int/tdr/svc/publications/training-guidelinepublications/trainers-project-planning-course.appendix I: Statement of Work: A Real-Life ExampleSection 1: PurposeBackgroundTeresa, a scientist training in the laboratory, wants to examine the possible role for alterations in thegene Sumacan in prostate cancer. She noted that Sumacan, which encodes a growth factor receptor,maps to a genetic region involved in human prostate cancer. Current studies in the lab focus on therole of Sumacan in brain tumors. Robert, another scientist training in the laboratory, is screeningdrugs that block Sumacan function; Anna, a graduate student, is elucidating the functional pathwaysSumacan is involved in; and David, a graduate student, is performing a mutational analysis of theSumacan gene. These same studies can be applied to prostate cancer, thereby opening up newpotential avenues for funding through prostate cancer foundations.92 excellence everywhere

appendix I continuedScope of Workn Examine whether the functional pathway for Sumacan is present in human prostate cancer cells.n Compare the expression of Sumacan in normal human prostate tissues and prostate cancers, andcorrelate expression levels with clinical outcome in prostate cancer.n Identify mutations in Sumacan in patients with prostate cancer.StrategyEach person in the lab is already working on different aspects of Sumacan biology in brain tumors. Ineach case, the work will be applied to prostate cancer cell lines that we will obtain from Mike, a colleaguein our department. We have identified two additional potential collaborators—Rajiv, a pathologistwho studies human prostate tissues and cancers, and Kathy, a geneticist who studies human prostatecancer families. We will use funds from our current grant to obtain preliminary findings. We plan to usethese findings to obtain another grant to the laboratory.Section 2: ObjectiveStatementInvestigate the possible role of Sumacan in prostate cancer.MeasuresMeasure #1. Our experiments will provide preliminary evidence to either support or deny a role forSumacan in prostate cancer.Specificationsn We will receive several requests for information about the research.n We will publish at least two research articles in the scientific literature.n We will present the research results to at least two conferences in one year.Section 3: constraintsLimitationsn The grant proposal is due June 1 next year. This means that the first research manuscript must besubmitted for publication by approximately January 1, and accepted by mid-April.n Our lab has limited funds to cover the generation of preliminary data, which means that productivitymust be reviewed monthly.Needsn Our lab needs to be able to grow prostate cancer cells.n Our lab needs to be able to handle human prostate cancer specimens.Section 4: Assumptionsn The current research team will be willing and able to perform prostate cancer studies in additionto their brain tumor studies.n The collaborators we have identified will be willing and able to work with our group or will providethe name of another person who wants to collaborate.Based on a real-world example provided by Milton W. Datta, Medical College of Wisconsin.project management93

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