THE DASH-SODIUM TRIAL - FNCE

11/19/2010Metabolic Sydrome• Prevalence at baseline: 32%• Reduced to 20% after 2 years• No differences among the dietsConclusion• Successful diets for weight loss can emphasize alarge range of macronutrient intakes.• These diets are made with foods that reduce riskof cardiovascular disease.• Serum lipids and insulin are improved on all suchdiets. But low-fat may not be best for metabolicsyndrome or diabetes.• Ongoing counseling sessions are important toachieve and maintain weight loss in all groups.• Successful diets for weight loss can be tailored toindividual patients’ personal and culturalpreferences to achieve long-term success.PoundsLost Trial Organization:Study Sites, Researchers, Funding• Harvard School of Public Health and Brigham &Women’s Hospital, Boston; F. Sacks, PI, StudyChairperson; Kathy McManus, Meryl LeBoff• Pennington Biomedical Research Center, LouisianaState University System, Baton Rouge, G. Bray PI;Donna Ryan, Steven Smith, Steven Anton, DonWilliamson, Cathy Champagne, Jennifer Rood• Coordinating Center: Channing Laboratory, Brigham &Women’s Hospital, V Carey Director; N Laranjo• National Heart Lung and Blood Institute, NIH; CayLoria, Eva Obarzanek, Project Officers• Investigator Initiated proposal to NHLBI funded bycooperative agreement grant to Harvard School ofPublic Heath.6