PEPROTECH

PEPROTECH ®www.peprotech.comManufacturer of Quality Cytokine ProductsPublished by PeproTech Inc.Rocky Hill, New Jersey USACopyright © 2011 by PeproTech Inc.1

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www.peprotech.com2011-2012 ⽤用⻑⾧長⾎血⾎血⽣生⽩白⽣生⾎血⽩白⼀一⽤用⾎血⽣生⼤大⽩白⽩白⽣生⽤用⾼高⽅方⽣生⽩白⽣生 ⾃自 ⽤用⽤用⽬目⽐比⾦金金 ⾎血 ⽤用⽤用⽬目PeproGrow-1 ................................................ 700-C100PeproGrow-2 ................................................ 700-C200PeproGrow 3 ................................................ 700-C300Serum Replacement Solution ............................. SR100Serum Replacement Solution-2 ......................... SR110Lipid Mixture Solution .................................... LM200⽐比⾦金金 ⾎血 ⽔水⾼高⼒力力 ⼒力力 ⽤用⽬目⾎血⽤用⾮非⽩白⽔水 ⾎血 ⼒力力 10

PEPROTECH ®www.peprotech.com⽩白⾼高⼒力力⼤大⽤用⽩白⽬目⽤用⽩白 Human BDNF .................................................... AF-450-02 ...........................................10 µg & 1mgHuman BMP-4 ................................................AF-120-05ET .........................................10 µg & 1mgHuman EGF ..................................................... AF-100-15 .........................................500 µg & 1mgHuman FGF-acidic ............................................AF-100-17A ..........................................50 µg & 1mgHuman FGF-basic ............................................AF-100-18B ..........................................50 µg & 1mgHuman flt3-Ligand ............................................ AF-300-19 ...........................................10 µg & 1mgHuman GM-CSF ................................................ AF-300-03 ...........................................20 µg & 1mgHuman Heregulinβ-1 ........................................ AF-100-03 ...........................................50 µg & 1mgHuman IFN-γ ..................................................... AF-300-02 .........................................100 µg & 1mgHuman IGF-I ..................................................... AF-100-11 .........................................100 µg & 1mgHuman IL-1β ..................................................AF-200-01B ..........................................10 µg & 1mgHuman IL-2 ...................................................... AF-200-02 ...........................................50 µg & 1mgHuman IL-3 ........................................................ AF-200-03 ...........................................10 µg & 1mgHuman IL-4 ....................................................... AF-200-04 ...........................................20 µg & 1mgHuman IL-6 ....................................................... AF-200-06 ...........................................20 µg & 1mgHuman IL-15 ..................................................... AF-200-15 ...........................................10 µg & 1mgHuman IL-16 ....................................................AF-200-16A ..........................................10 µg & 1mgHuman IL-17 ..................................................... AF-200-17 ...........................................25 µg & 1mgHuman IL-21 ..................................................... AF-200-21 ...........................................10 µg & 1mgHuman KGF ....................................................... AF-100-19 ...........................................10 µg & 1mgHuman M-CSF .................................................. AF-300-25 ...........................................10 µg & 1mgHuman MCP-1 .................................................. AF-300-04 ...........................................20 µg & 1mgHuman β-NGF ................................................... AF-450-01 ...........................................20 µg & 1mgHuman PDGF-BB ............................................AF-100-14B ..........................................10 µg & 1mgHuman PlGF-1 .................................................. AF-100-06 ...........................................25 µg & 1mgHuman SCF ....................................................... AF-300-07 ...........................................10 µg & 1mgHuman TNF-α .................................................AF-300-01A ..........................................50 µg & 1mgHuman TPO ....................................................... AF-300-18 ...........................................10 µg & 1mgHuman VEGF .................................................... AF-100-20 ...........................................10 µg & 1mgMurine IL-3 ........................................................ AF-213-13 ...........................................10 µg & 1mgMurine IL-4 ....................................................... AF-214-14 ...........................................20 µg & 1mgMurine GM-CSF ................................................ AF-315-03 ...........................................20 µg & 1mgMurine M-CSF .................................................. AF-315-02 ...........................................10 µg & 1mgMurine SCF ....................................................... AF-250-03 ...........................................10 µg & 1mgRat TPO.............................................................. AF-400-34 ...........................................10 µg & 1mg11

www.peprotech.com2011-2012 Activin ASynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Activin A 120-14 Insect cells 26.0 kDa 1µg 5µg 1mgHuman Activin A 120-14E E.coli 26.0 kDa 2µg 10µg 1mgAdditional sizes available please inquireBioassay analysis of human Activin A.Determined by its ability to inhibit theproliferation of mouse MCP-11 cells.OD (490 nm)2.001.601.200.800.40Bioassay for Human Activin A using MPC-11 cells0.000.00 0.01 0.10 1.00 10.00h-Activin A (ng/ml) [log scale]AHuman Activin A; A; PeproTech; Cat# 120-14EActivin BHUMAN Human ACTIVIN Activin A; A; PEPROTECH; PeproTech; CAT# Cat# 120-14Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Activin B 120-15 Insect cells 25.6 kDa 1µg 5µg 1mgAdditional sizes available please inquireAdiponectinSynonyms: Acrp30, apM-1, adipoQ, gelatin-binding protein, 28kD (GBP28)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Adiponectin 450-24 Insect cells 25.0-36.0 kDa 5µg 25µg 1mgAdditional sizes available please inquireAITRL Activation-induced TNFR member ligandSynonyms: TNFSF18, GITRL, TL6Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman AITRL 310-22 E.coli 14.3 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human AITRL 500-P244 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human AITRL 500-P244bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested12

PEPROTECH ®www.peprotech.comAminopeptidaseSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BAeromonas Aminopeptidase 100-10 E.coli 31.4 kDa 100µg 500µg 1mgAdditional sizes available please inquireAmphiregulinSynonyms: ARRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Amphiregulin 100-55B E.coli 11.3 kDa 10µg 50µg 1mgAdditional sizes available please inquireAANG-1 Angiopoietin-1Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Angiopoietin-1 130-06 HeLa cells 60.0-70.0 kDa 5µg 20µg 1mgAdditional sizes available please inquireApoA-1 Apolipoprotein A-1Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman ApoA-1 350-11 E.coli 28.2 kDa 20µg 100µg 1mgAdditional sizes available please inquire13

www.peprotech.com2011-2012 ApoE2 Apolipoprotein E2Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman ApoE2 350-12 E.coli 34.3 kDa 100µg 500µg 1mgAdditional sizes available please inquireApoE3 Apolipoprotein E3Synonyms: noneARecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman ApoE3 350-02 E.coli 34.0 kDa 100µg 500µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human ApoE3 500-P238 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human ApoE3 500-P238bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedApoE4 Apolipoprotein E4Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman ApoE4 350-04 E.coli 34.4 kDa 100µg 500µg 1mgAdditional sizes available please inquireApo-SAASynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Apo-SAA 300-13 E.coli 11.7 kDa 10µg 50µg 1mgHuman Apo-SAA1 300-53 E.coli 11.7 kDa 10µg 50µg 1mgAdditional sizes available please inquire14

PEPROTECH ®www.peprotech.comAPRIL A proliferating-inducing ligandSynonyms: TNFSF13, TRDL-1αRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman APRIL 310-10C Insect cells 16.3 kDa 2µg 10µg N/AMurine APRIL 315-13 E.coli 21.9 kDa 5µg 20µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human APRIL 500-P192 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human APRIL 500-P192bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman carcinoid (FFPE) stained with rabbit antihumanAPRIL at 0.25 µg/mL. Staining of tumor cells.Tissue samples were provided by the Cooperative Human Tissue Network,which is funded by the National Cancer Institute. Other investigators mayhave received specimens from the same subjects. Photograph provided byPatsy Ruegg for PeproTech.AArteminSynonyms: ARTRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Artemin 450-17 E.coli 24.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Artemin 500-P245 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Artemin 500-P245bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedkDa148Representative Western Transfer (Blot) analysis ofhuman Artemin using Rabbit anti-human Arteminat 0.20µg/ml.60423022176415

www.peprotech.com2011-2012 4-1BBLSynonyms: TNFSF9, CD137LRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman 4-1BBL 310-11 E.coli 19.5 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human 4-1BBL 500-P169 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human 4-1BBL 500-P169bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested4-1BB (Receptor)Synonyms: TNFRSF9, CD137 antigenBRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman 4-1BB receptor 310-15 E.coli 17.7 kDa 5µg 20µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human 4-1BB receptor 500-P167G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human 4-1BB receptor 500-P167Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human 4-1BB receptor CATALOG # 900-K208ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationB71Polyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine B71 500-P128 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine B71 500-P128bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested16

PEPROTECH ®www.peprotech.comBAFF B-cell activating factor belonging to the TNF familySynonyms: TNFSF13B, TALL-1, BLyS, THANK, zTNF4Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BAFF 310-13 E.coli 17.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human BAFF 500-P163G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human BAFF 500-P163Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human BAFF 500-M64 Mouse E 500µgBAFF enhances Ig secretion by human B cellsco-stimulated through the BcR. Ig secretion wasdetermined using heavy chain specific ELISAsafter 12-14 days of culture. (S.G. Tangye et. al.Seminars in Immunology 18 (2006) 305-317.BBAFF Receptor B-cell activating factor belonging to the TNF receptor familySynonyms: BAFFR, TNFRSF13CRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BAFF Receptor 310-13R E.coli 7.7 kDa 10µg 50µg 1mgAdditional sizes available please inquire17

www.peprotech.com2011-2012 BDNF Brain-derived neurotrophic factorSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BDNF 450-02 E.coli 27.0 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman BDNF AF-450-02 E.coli 27.0 kDa N/A 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human BDNF 500-P84 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human BDNF 500-P84bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedBBetacellulinSynonyms: BTCRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Betacellulin 100-50 E.coli 9.0 kDa 5µg 20µg 1mgMurine Betacellulin 315-21 E.coli 9.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Betacellulin 500-P254 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human Betacellulin 500-P254bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human Betacellulin CATALOG # 900-K372ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination20

PEPROTECH ®www.peprotech.comBMP-2 Bone morphogenetic protein-2Synonyms: BMP-2ARecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BMP-2 120-02 E.coli 26.0 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human BMP-2 500-P195 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human BMP-2 500-P195bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human BMP-2 CATALOG # 900-K255ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationBBMP-3 Bone morphogenetic protein-3Synonyms: Osteogenin, BMP-3ARecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BMP-3 120-24B E.coli 25.2 kDa 10µg 50µg 1mgAdditional sizes available please inquireBMP-4 Bone morphogenetic protein-4Synonyms: BMP-2B, DVR4Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BMP-4 120-05 HeLa cells 31.0-36.0 kDa 1µg 5µg 1mgHuman BMP-4 120-05ET E.coli 23.8 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman BMP-4 AF-120-05ET E.coli 23.8 kDa N/A 10µg 1mgMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human BMP-4 500-M121 Mouse E, WB, N 500µgAdditional sizes available please inquireKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested21

www.peprotech.com2011-2012 BMP-6 Bone morphogenetic protein-6Synonyms: VGRRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BMP-6 120-06 HEK 293 cells 30.0-36.0 kDa 2µg 10µg 1mgAdditional sizes available please inquireBMP-7 Bone morphogenetic protein-7Synonyms: OP-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BMP-7 120-03 CHO cells 28.8 kDa 2µg 10µg 1mgAdditional sizes available please inquireBPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human BMP-7 500-P198 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human BMP-7 500-P198bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human BMP-7 500-M123 Mouse E 500µgBMP-13/CDMP-2 Bone morphogenetic protein-13/CDMP-2Synonyms: Cartilage-derived morphogenetic protein-2, GDF-6Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BMP-13/CDMP-2 120-04 E.coli 27.0 kDa 10µg 50µg 1mgAdditional sizes available please inquire22

PEPROTECH ®www.peprotech.comBRAK/CXCL14 Breast and kidney-expressed chemokineSynonyms: CXCL14, bolekineRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman BRAK 300-50 E.coli 9.4 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human BRAK 500-P237 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human BRAK 500-P237bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman breast invasive ductal carcinoma (FFPE) stainedwith rabbit anti-human BRAK at 0.25 µg/mL.Staining of tumor cells in ducts.Tissue samples were provided by the Cooperative Human Tissue Network, whichis funded by the National Cancer Institute. Other investigators may have receivedspecimens from the same subjects.Photograph provided by Patsy Ruegg for PeproTech.B-CC10/CCL6Synonyms: CCL6, MRP-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine C10 250-06 E.coli 10.7 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine C10 500-P112 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine C10 500-P112bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedCarboxypeptidaseSynonyms: Cpb1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BRat Carboxypeptidase 400-00 E.coli 35.1 kDa 5µg 25µg 1mgAdditional sizes available please inquire23

www.peprotech.com2011-2012 Cardiotrophin-1Synonyms: CT-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Cardiotrophin-1 300-32 E.coli 21.5 kDa 2µg 10µg 1mgMurine Cardiotrophin-1 250-25 E.coli 21.3 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Cardiotrophin-1 500-P101 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human Cardiotrophin-1 500-P101bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedsCD14 soluble CD14CSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sCD14 110-01 HEK 293 cells 41.6 kDa 10µg 50µg 1mgAdditional sizes available please inquiresCD22 soluble CD22Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sCD22 100-01 CHO cells 75.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sCD22 500-P227 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human sCD22 500-P227bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested24

PEPROTECH ®www.peprotech.comsCD23 soluble CD23Synonyms: CD23 antigen, Fc-epsilon-RII, Lymphocyte IgE receptor, BLAST-2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sCD23 310-26 E.coli 19.2 kDa 5µg 20µg 1mgAdditional sizes available please inquiresCD27 Ligand soluble CD27 LigandSynonyms: TNFSF27, CD70, CD27LRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sCD27 Ligand/TNFSF27 310-30 CHO cells 18.8 kDa 10µg 50µg 1mgAdditional sizes available please inquireCsCD30 Ligand soluble CD30 LigandSynonyms: TNFSF8, CD153 antigen, CD30LRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sCD30 Ligand/TNFSF8 450-42 CHO cells 21.3 kDa 10µg 50µg 1mgAdditional sizes available please inquire25

www.peprotech.com2011-2012 sCD40 Ligand soluble CD40 LigandSynonyms: TNFSF5, TRAP, CD154, gp39, T-BAMRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sCD40 Ligand 310-02 E.coli 16.3 kDa 10µg 50µg 1mgMurine sCD40 Ligand 315-15 E.coli 16.4 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sCD40 Ligand 500-P142 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human sCD40 Ligand 500-P142bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human sCD40 Ligand 500-P142G Goat I, E, WB, NA 50µg 100µg 1mgBiot. anti-human sCD40 Ligand 500-P142Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedCELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human sCD40 Ligand CATALOG # 900-K145Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human sCD40 Ligand CATALOG # 900-M145ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationHuman cervical squamous cell carcinoma (FFPE) stainedwith goat anti-human sCD40L at 2.5 µg/ml.Tissue samples wereprovided by the Cooperative Human Tissue Network, which is funded by the NCI.Other investigators may have received specimens from the same subject.Photograph provided by Patsy Ruegg for Peprotech.sCD100Synonyms: Semaphorin-4D, BB18, A8, GR3Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sCD100 310-29 CHO cells 78.9 kDa 5µg 20µg 1mgAdditional sizes available please inquire26

PEPROTECH ®www.peprotech.comCDNF Cerebral dopamine neurotrophic factorSynonyms: ARMETL1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman CDNF 450-05 E.coli 18.5 kDa 5µg 25µg 1mgAdditional sizes available please inquireChemerinSynonyms: Tazaroyene-induced gene 2 (TIG2), RARRES2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Chemerin 300-66 E.coli 15.6 kDa 5µg 25µg 1mgAdditional sizes available please inquireCNTF Ciliary neurotrophic factorSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman CNTF 450-13 E.coli 22.7 kDa 5µg 20µg 1mgRat CNTF 450-50 E.coli 22.7 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human CNTF 500-P140 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human CNTF 500-P140bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat CNTF 500-P79 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat CNTF 500-P79bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human CNTF CATALOG # 900-K158CELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination27

www.peprotech.com2011-2012 CTACK/CCL27 Cuteaneous T-cell attracting chemokineSynonyms: CCL27, ALP, Skinkine, EskineRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman CTACK 300-54 E.coli 9.8 kDa 5µg 20µg 1mgMurine CTACK 250-26 E.coli 10.9 kDa 5µg 20µg 1mgAdditional sizes available please inquireCCTGF Connective tissue growth factorSynonyms: CCN2, Hypertrophic chondrocyte-specific protein 24 (HCS24)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman CTGF (98 a.a.) 120-19 E.coli 11.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human CTGF 500-P252 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human CTGF 500-P252bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human CTGF CATALOG # 900-K317ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationCTGFL/WISP-2 Connective tissue growth factor-like proteinSynonyms: CCN5, CT-58Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman CTGFL/WISP-2 120-16 E.coli 24.8 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human CTGFL/WISP-2 500-P212 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human CTGFL/WISP-2 500-P212bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I= IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested28

PEPROTECH ®www.peprotech.comCTLA-4Polyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine CTLA-4 500-P147 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine CTLA-4 500-P147bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedCXCL16Synonyms: SRPSOXRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman CXCL16 300-55 E.coli 10.1 kDa 5µg 25µg 1mgMurine CXCL16 250-28 E.coli 9.9 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human CXCL16 500-P200 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human CXCL16 500-P200bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine CXCL16 500-P201G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-murine CXCL16 500-P201Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedCELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human CXCL16 CATALOG # 900-K230Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human CXCL16 CATALOG # 900-M230ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationCYR61Synonyms: CNN1, GIGI proteinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman CYR61 120-25 E.coli 39.5 kDa 5µg 20µg 1mgAdditional sizes available please inquire29

www.peprotech.com2011-2012 DDAHSynonyms: Dimethylarginine dimethylaminohydrolase-1, Dimethylargininase-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman DDAH-1 150-13 E. coli 31.4 kDa 10µg 50µg 1mgAdditional sizes available please inquireDKK-1Synonyms: Dickkopf-related protein-1, Dickkopf-1, SKRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman DKK-1 120-30 HEK 293 cells 35.0-40.0 kDa 2µg 10µg 1mgAdditional sizes available please inquireDsDLL-1Synonyms: Delta-like protein-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sDLL-1 140-08 HEK 293 cells 56.0-60.0 kDa 5µg 25µg 1mgAdditional sizes available please inquiresDLL-4Synonyms: Delta-like protein-4, Drosophila Delta homolog 4Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sDLL-4 140-07 HEK 293 cells 54.0 kDa 5µg 25µg 1mgAdditional sizes available please inquire30

PEPROTECH ®www.peprotech.comEGF Epidermal growth factorSynonyms: Urogastrone, URGRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine EGF 315-09 E.coli 6.0 kDa 100µg 500µg 1mgRat EGF 400-25 E.coli 6.2 kDa 20µg 100µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman EGF AF-100-15 E.coli 6.2 kDa 100µg 500µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human EGF 500-P45 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human EGF 500-P45bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine EGF 500-P174G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine EGF 500-P174Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-rat EGF 500-P277 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat EGF 500-P277bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedEMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-murine EGF 500-M136 Rat E 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human EGF CATALOG # 900-K05Murine EGF CATALOG # 900-K179Rat EGF CATALOG # 900-K390Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human EGF CATALOG # 900-M05Rat EGF CATALOG # 900-M390ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationNormal human skin (FFPE) stained withrabbit anti-human EGF at 1.0 µg/ml. Stainingof apocrine gland epithelial cells andsecretory cells. Photograph by PeproTech.31

www.peprotech.com2011-2012 EGF ReceptorSynonyms: ErbB1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman EGF Receptor 100-15R CHO cells 68.5 kDa 2µg 10µg 1mgAdditional sizes available please inquireEG-VEGF Endocrine gland-derived vascular endothelial growth factorSynonyms: Prokineticin, PROK1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman EG-VEGF 100-44 E.coli 9.6 kDa 5µg 20µg 1mgAdditional sizes available please inquireEPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human EG-VEGF 500-P188G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human EG-VEGF 500-P188Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human EG-VEGF CATALOG # 900-K244ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationEMAP-II Endothelial-monocyte activating polypeptide IIPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size B 1mgAnti-human EMAP-II 500-P172G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human EMAP-II 500-P172Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested32

PEPROTECH ®www.peprotech.comENA-78/LIX (CXCL5) Epithelial neutrophil activating peptide-78Synonyms: CXCL5, LIX (murine)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman ENA-78 (74 a.a.) 300-22 E.coli 8.0 kDa 5µg 20µg 1mgHuman ENA-78 (71 a.a.) 300-22B E.coli 8.0 kDa 5µg 20µg 1mgMurine LIX (93 a.a.) 250-17 E.coli 9.8 kDa 5µg 20µg 1mgMurine LIX (70 a.a.) 250-36 E.coli 7.6 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human ENA-78 500-P91 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human ENA-78 500-P91bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine LIX 500-P146 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine LIX 500-P146bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedEndostatinESynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Endostatin 150-01 E.coli 20.2 kDa 20µg 100µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Endostatin 500-P262 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Endostatin 500-P262bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedAnti-Human Endostatin (Catalog #500-P262) *Human breast invasive ductal carcinoma (FFPE)stained with Rabbit Anti-Human Endostatin at 0.25µg/mL. Staining of endothelial cells.Tissue samples were provided by the Cooperative Human Tissue Network,which is funded by the National Cancer Institute. Other investigators mayhave received specimens from the same subjects.33

www.peprotech.com2011-2012 EnterokinaseSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Enterokinase 450-48C CHO cells 108.7 kDa 10µg 50µg 1mgAdditional sizes available please inquireEotaxin/CCL11Synonyms: CCL11ERecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Eotaxin 300-21 E.coli 8.3 kDa 5µg 20µg 1mgMurine Eotaxin 250-01 E.coli 8.4 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Eotaxin 500-P41 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human Eotaxin 500-P41bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human Eotaxin 500-P41G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human Eotaxin 500-P41Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine Eotaxin 500-P67 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine Eotaxin 500-P67bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human Eotaxin 500-M25 Mouse E, WB 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human Eotaxin CATALOG # 900-K69Murine Eotaxin CATALOG # 900-K68ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationChemotaxis analysis of human Eotaxin.Data shows the migration of purified humaneosinophils in response to human Eotaxin.34

PEPROTECH ®www.peprotech.comEotaxin-2/CCL24Synonyms: CCL24, MPIF-2, CkB-6Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Eotaxin-2 300-33 E.coli 8.8 kDa 5µg 20µg 1mgMurine Eotaxin-2 250-22 E.coli 10.3 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Eotaxin-2 500-P103G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human Eotaxin-2 500-P103Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine Eotaxin-2 500-P175G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine Eotaxin-2 500-P175Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human Eotaxin-2 500-M31 Mouse E, WB 500µgEotaxin-3/CCL26ESynonyms: CCL26Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Eotaxin-3 300-48 E.coli 8.4 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Eotaxin-3 500-P156G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human Eotaxin-3 500-P156Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human Eotaxin-3 500-M32 Mouse E, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human Eotaxin-3 CATALOG # 900-K167ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination35

www.peprotech.com2011-2012 EpigenSynonyms: EPG, Epithelial mitogenRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Epigen 100-51 E.coli 7.9 kDa 5µg 25µg 1mgAdditional sizes available please inquireEpiregulinSynonyms: EREGRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Epiregulin 100-04 E.coli 5.6 kDa 5µg 25µg 1mgAdditional sizes available please inquireEBioassay analysis of humanEpiregulin (proliferation) usingmouse Balb/3T3 cells.E-SelectinSynonyms: Endothelial leukocyte adhesion molecule-1 (ELAM1), CD62E, SELERecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman E-Selectin 150-15 CHO cells 58.6 kDa 10µg 50µg 1mgAdditional sizes available please inquire36

PEPROTECH ®www.peprotech.comExodus-2/CCL21Synonyms: CCL21, 6Ckine, SLCRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Exodus-2 300-35 E.coli 12.2 kDa 5µg 20µg 1mgMurine Exodus-2 250-13 E.coli 12.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Exodus-2 500-P109 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human Exodus-2 500-P109bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine Exodus-2 500-P114 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine Exodus-2 500-P114bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedAnti-Human Exodus-2(Catalog #500-P109)Human prostate malignant adenocarcinoma(FFPE) stained withRabbit Anti-Human Exodus-2 at0.75 µg/mL.Tissue samples were provided by the CooperativeHuman Tissue Network, which is funded by theNational Cancer Institute. Other investigators mayhave received specimens from the same subjects.E37

www.peprotech.com2011-2012 sFas Ligand soluble Fas LigandSynonyms: TNFSF6, sFasL, CD95L, Apo I Ligand, APTLRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sFas Ligand 310-03H CHO cells 17.9 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sFas Ligand 500-P184G Goat I, E, WB, N 50µg 100µg 1mgBiot. anti-human sFas Ligand 500-P184Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedFHuman angiosarcoma (FFPE) stained with goatanti-human sFas Ligand at 2.5 µg/mL. Photographprovided by Patsy Ruegg for PeproTech.sFas Receptor soluble Fas receptorSynonyms: TNFRSF6, CD95, Fas antigen, Apo IRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sFas receptor 310-20 E.coli 17.6 kDa 5µg 20µg 1mgAdditional sizes available please inquireBioassay analysis of human sFasReceptor. Determined by its abilityto inhibit sFas Ligand inducedcytotoxicity using Jurkat cells.38

PEPROTECH ®www.peprotech.comFGF Fibroblast growth factorSynonyms: See FGF chart on pages 143-144.Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman FGF-acidic 100-17A E.coli 15.8 kDa 10µg 50µg 1mgMurine FGF-acidic 450-33A E.coli 15.9 kDa 10µg 50µg 1mgHuman FGF-basic 100-18B E.coli 17.2 kDa 10µg 50µg 1mgMurine FGF-basic 450-33 E.coli 16.2 kDa 10µg 50µg 1mgRat FGF-basic 400-29 E.coli 16.3 kDa 10µg 50µg 1mgHuman FGF-4 100-31 E.coli 19.7 kDa 5µg 25µg 1mgHuman FGF-5 100-34 E.coli 27.6 kDa 10µg 50µg 1mgHuman FGF-6 100-30 E.coli 18.7 kDa 5µg 25µg 1mgHuman FGF-7/KGF 100-19 E.coli 18.9 kDa 2µg 10µg 1mgHuman FGF-8 100-25 E.coli 22.4 kDa 5µg 25µg 1mgHuman FGF-9 100-23 E.coli 23.4 kDa 5µg 20µg 1mgMurine FGF-9 450-30 E.coli 23.3 kDa 2µg 10µg 1mgHuman FGF-10 100-26 E.coli 19.3 kDa 5µg 25µg 1mgHuman FGF-16 100-29 E.coli 23.7 kDa 5µg 25µg 1mgHuman FGF-17 100-27 E.coli 22.7 kDa 5µg 25µg 1mgHuman FGF-18 100-28 E.coli 20.1 kDa 5µg 25µg 1mgHuman FGF-19 100-32 E.coli 21.8 kDa 5µg 25µg 1mgHuman FGF-20 100-41 E.coli 23.2 kDa 3µg 15µg 1mgHuman FGF-21 100-42 E.coli 19.5 kDa 5µg 25µg 1mgHuman FGF-23 100-52 E.coli 25.4 kDa 5µg 20µg 1mgAdditional sizes available please inquireFAnimal-Free Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman FGF-acidic AF-100-17A E.coli 15.8 kDa N/A 50µg 1mgHuman FGF-basic AF-100-18B E.coli 17.2 kDa N/A 50µg 1mgHuman FGF-7/KGF AF-100-19 E.coli 18.9 kDa N/A 10µg 1mgAdditional sizes available please inquireFGF continued on next page...39

www.peprotech.com2011-2012 FGF continued...FPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human FGF-acidic 500-P17 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human FGF-acidic 500-P17bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human FGF-basic 500-P18 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human FGF-basic 500-P18bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human FGF-4 500-P158 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human FGF-4 500-P158bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human FGF-7/KGF 500-P19 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human FGF-7/KGF 500-P19bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine FGF-9 500-P66 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine FGF-9 500-P66bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human FGF-10 500-P151G Goat I, E, WB, NA 50µg 100µg 1mgBiot. anti-human FGF-10 500-P151Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-human FGF-16 500-P160G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human FGF-16 500-P160Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-human FGF-17 500-P152 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human FGF-17 500-P152bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human FGF-17 500-P152G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human FGF-17 500-P152Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human FGF-basic 500-M38 Mouse I, E, WB 500µgAnti-human FGF-5 500-M40 Mouse E, N 500µgKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human FGF-basic CATALOG # 900-K08Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human FGF-basic CATALOG # 900-M08ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationFGF continued on next page...40

PEPROTECH ®www.peprotech.comFGF continued...Human carcinoid tissue (FFPE) stained withgoat anti-human FGF-10 at 1.0 µg/ml.Tissue samples were provided by the Cooperative HumanTissue Network, which is funded by the NCI. Otherinvestigators may have received specimens from the samesubject. Photograph provided by Patsy Ruegg for PeproTech.Normal skin (FFPE) stained with Rabbit antihumanKGF/FGF-7 at 0.5 µg/ml. Staining ofgland epithelial cells. Photograph by Peprotech.FHuman breast invasive ductal carcinoma(FFPE) stained with rabbit anti-humanFGF-basic at 0.25 µg/ml.Tissue samples were provided by the Cooperative HumanTissue Network, which is funded by the NCI. Otherinvestigators may have received specimens from the samesubject. Photograph by PeproTech.41

www.peprotech.com2011-2012 flt3-LigandSynonyms: flt3L, Fms-related tyrosine kinase 3 ligandRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman flt3-Ligand 300-19 E.coli 17.6 kDa 2µg 10µg 1mgMurine flt3-Ligand 250-31L E.coli 18.6 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman flt3-Ligand AF-300-19 E.coli 17.6 kDa N/A 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human flt3-Ligand 500-P42 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human flt3-Ligand 500-P42bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedFFollistatinSynonyms: FS, activins-binding proteinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Follistatin 120-13 E.coli 31.5 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Follistatin 500-P207 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human Follistatin 500-P207bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human Follistatin CATALOG # 900-K299ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination42

PEPROTECH ®www.peprotech.comFractalkine/CX3CL1Synonyms: CX3CL1, NeurotactinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Fractalkine 300-31 E.coli 8.5 kDa 5µg 20µg 1mgRat Fractalkine 400-26 E.coli 8.7 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Fractalkine 500-P98 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Fractalkine 500-P98bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedsFRP-1 soluble Frizzled Related Protein-1Synonyms: Secreted Apoptosis Related Protein-2, SARP-2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sFRP-1 120-29 HeLa cells 31.0-36.0 kDa 5µg 20µg 1mgAdditional sizes available please inquireF-GgAcrp30Synonyms: Adipolean (human)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman gAcrp30/Adipolean 450-21 E.coli 16.6 kDa 5µg 25µg 1mgMurine gAcrp30 450-27 E.coli 16.6 kDa 5µg 25µg 1mgHuman gAcrp30/Adipolean Variant 450-20 E.coli 18.1 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human gAcrp30/Adipolean 500-P193G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human gAcrp30/Adipolean 500-P193Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-human Adipolean Variant 500-P205 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Adipolean Variant 500-P205bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested43

www.peprotech.com2011-2012 Galectin-1Synonyms: beta-galactoside-binding lectin L-14-I, Galaptin, 14 kDa lectin, S-LAC lectin 1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Galectin-1 450-39 E.coli 14.5 kDa 10µg 50µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Galectin-1 500-P210 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Galectin-1 500-P210bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedGGalectin-3Synonyms: Galactose-specific lectin-3, IgE-binding protein, MAC2, L-29, CPB-35Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Galectin-3 450-38 E.coli 26.0 kDa 10µg 50µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Galectin-3 500-P246 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Galectin-3 500-P246bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman pancreas ductal adenocarcinoma(FFPE) stained with rabbit anti-humanGalectin-3 at 31.25 ng/mL. Staining ofnerve cells and tumor cells. (photo.1, left)Staining of tumor cells. (photo.2, right)Tissue samples were provided by the Cooperative HumanTissue Network, which is funded by the NationalCancer Institute. Other investigators may have receivedspecimens from the same subjects.Photograph provided byPatsy Ruegg for PeproTech.44

PEPROTECH ®www.peprotech.comGCP-2/CXCL6 Granulocyte chemotactic protein-2Synonyms: CXCL6Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GCP-2 300-41 E.coli 7.9 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human GCP-2 500-P120 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human GCP-2 500-P120bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedkDa148Representative Western Transfer (Blot) analysis ofhuman GCP-2 using Rabbit anti-human GCP-2at 0.20 µg/ml.60423022176G4Human GCP-2 induceschemotaxis of human neutrophils.45

www.peprotech.com2011-2012 G-CSF Granulocyte colony-stimulating factorSynonyms: CSF-3, MGI-1G, GM-CSFβ, pluripoietinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman G-CSF 300-23 E.coli 18.7 kDa 2µg 10µg 1mgMurine G-CSF 250-05 E.coli 19.0 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human G-CSF 500-P43 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human G-CSF 500-P43bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine G-CSF 500-P69 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine G-CSF 500-P69bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedGELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human G-CSF CATALOG # 900-K77Murine G-CSF CATALOG # 900-K103ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationBioassay analysis of murine G-CSF (proliferation)using mouse M-NFS-60 cells.GDF-2 Growth and differentiation factor-2Synonyms: Growth/Differentiation Factor-2, BMP-9Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GDF-2 120-07 CHO cells 24.1 kDa 2µg 10µg 1mgAdditional sizes available please inquire46

PEPROTECH ®www.peprotech.comGDF-3 Growth and differentiation factor-3Synonyms: UNQ222/PRO248Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GDF-3 120-22 E.coli 26.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human GDF-3 500-P235 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human GDF-3 500-P235bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedGDF-5/CDMP-1 Growth and differentiation factor-5Synonyms: BMP-14, Cartilage-Derived Morphogenetic Protein-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GDF-5/CDMP-1 120-01 E.coli 27.0 kDa 10µg 50µg 1mgAdditional sizes available please inquireGGDF-11 Growth and differentiation factor-11Synonyms: BMP-11Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GDF-11 120-11 E.coli 25.0 kDa 5µg 20µg 1mgAdditional sizes available please inquireGDF-15/MIC-1 Growth and differentiation factor-15Synonyms: Placental TGF-β, Prostate differentiation factorProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GDF-15/MIC-1 120-28 cell culture 24.5 kDa 5µg 20µg 1mgAdditional sizes available please inquire47

www.peprotech.com2011-2012 GDNF Glial-derived neurotrophic factorSynonyms: ATF-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GDNF 450-10 E.coli 30.4 kDa 2µg 10µg 1mgMurine GDNF 450-44 E.coli 30.2 kDa 2µg 10µg 1mgRat GDNF 450-51 E.coli 30.0 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human GDNF 500-P81 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human GDNF 500-P81bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedkDaGRepresentative Western Transfer (Blot) analysis ofhuman GDNF using Rabbit anti-human GDNFat 0.20µg/ml.148604230221764GLP-1 Glucagon-like peptideSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GLP-1 (7-36 a.a.) 130-08 E.coli 3.3 kDa 200µg 1000µg 5mgAdditional sizes available please inquireGlu-CSynonyms: V8 ProteaseRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BStaphylococcus Glu-C 450-46 E.coli 29.1 kDa 50µg 250µg 1mgAdditional sizes available please inquire48

PEPROTECH ®www.peprotech.comGM-CSF Granulocyte/macrophage colony stimulating factorSynonyms: CSF-2, Pluripoietin-α, MGI-1GMRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GM-CSF 300-03 E.coli 14.6 kDa 5µg 20µg 1mgMurine GM-CSF 315-03 E.coli 14.2 kDa 5µg 20µg 1mgRat GM-CSF 400-23 E.coli 14.5 kDa 5µg 20µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman GM-CSF AF-300-03 E.coli 14.6 kDa N/A 20µg 1mgMurine GM-CSF AF-315-03 E.coli 14.2 kDa N/A 20µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human GM-CSF 500-P33 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human GM-CSF 500-P33bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine GM-CSF 500-P65 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine GM-CSF 500-P65bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedGELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells..Human GM-CSF CATALOG # 900-K30Murine GM-CSF CATALOG # 900-K55ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using Murine GM-CSF ELISAdevelopment kit.49

www.peprotech.com2011-2012 GMF-β Glial Maturation Factor-betaSynonyms: GMFβRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GMF-β 450-37 E.coli 16.5 kDa 2µg 10µg 1mgAdditional sizes available please inquireGranzyme BSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine Granzyme B 140-03 Baculovirus 28.9 kDa 2µg 10µg 1mgAdditional sizes available please inquireG50

PEPROTECH ®www.peprotech.comGROα/MGSA, GROβ, GROγ Growth regulated proteinSynonyms: GROα: CXCL1, GRO1, MGSAα, KC, NAP-3, CINCGROβ: CXCL2, GRO2, MGSAβ, MIP-2αGROγ: CXCL3, GRO3, MIP-2βRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman GRO/MGSA (CXCL1) 300-11 E.coli 7.8 kDa 5µg 25µg 1mgMurine KC (CXCL1) 250-11 E.coli 7.8 kDa 5µg 20µg 1mgRat GRO/KC (CXCL1) 400-10 E.coli 7.8 kDa 5µg 25µg 1mgHuman GROβ (CXCL2) 300-39 E.coli 7.9 kDa 2µg 10µg 1mgMurine MIP-2 (CXCL2) 250-15 E.coli 7.8 kDa 5µg 20µg 1mgRat GROβ/MIP-2 (CXCL2) 400-11 E.coli 7.9 kDa 5µg 25µg 1mgHuman GROγ (CXCL3) 300-40 E.coli 7.9 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human GRO/MGSA 500-P92 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human GRO/MGSA 500-P92bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine KC 500-P115 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine KC 500-P115bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat GRO/KC 500-P74 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat GRO/KC 500-P74bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human GROβ 500-P104 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human GROβ 500-P104bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine MIP-2 500-P130 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine MIP-2 500-P130bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat GROβ/MIP-2 500-P75 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat GROβ/MIP-2 500-P75bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human GROγ 500-P105 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human GROγ 500-P105bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedGELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human GRO/MGSA CATALOG # 900-K38Human GROβ CATALOG # 900-K120Rat GRO/KC CATALOG # 900-K57Murine MIP-2 CATALOG # 900-K152Murine KC CATALOG # 900-K127Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Murine KC CATALOG # 900-M127ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination51

www.peprotech.com2011-2012 HB-EGF Heparin-binding EGF-like growth factorSynonyms: HBEGF, Diphtheria toxin receptor, DT-RRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman HB-EGF 100-47 E.coli 9.8 kDa 10µg 50µg 1mgAdditional sizes available please inquireHCC-1/CCL14 Hemofiltrate CC chemokine-1Synonyms: CCL14, HCC-3, NCC-2HRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman HCC-1 (72 a.a.) 300-38 E.coli 8.4 kDa 2µg 10µg 1mgHuman HCC-1 (66 a.a.) 300-38B E.coli 7.7 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human HCC-1 500-P106 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human HCC-1 500-P106bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman HCC-1 induceschemotaxis of humanmonocytes.52

PEPROTECH ®www.peprotech.comHeregulinβ-1Synonyms: HRG, Neuregulin1 (NRG), Breast cancer cell differentiation factor p45, ARIA (Acetylcholinereceptor inducing activity), glial factor, Neu differentiation factor (rat)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Heregulinβ-1 100-03 E.coli 7.5 kDa 10µg 50µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman Heregulinβ-1 AF-100-03 E.coli 7.5 kDa N/A 50µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Heregulinβ-1 500-P288 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human Heregulinβ-1 500-P288bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHSDS-PAGE gel analysis under non-reducing conditionsfor human HCC-1 (Lane 1), HB-EGF (Lane 2),and Heregulinβ-1 (Lane 3), markers (Lane 4).HGF Hepatocyte growth factorSynonyms: Scatter factor (SF), Hepatopoietin (HPTA)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size B

www.peprotech.com2011-2012 HVEM-FcSynonyms: TNFSFR14, HVEM, ATAR, TR2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman HVEM-Fc 310-27 Insect cells 88.5 kDa 20µg 100µg 1mgAdditional sizes available please inquireSDS-PAGE gel analysis under non-reducing conditions forhuman HGF(Lane 1), HVEM-Fc (Lane 2), and markers(Lane 3). Due to glycosylation HVEM-Fc migrates higher.

PEPROTECH ®www.peprotech.comICAM-1 Intercellular adhesion molecule-1Synonyms: Major group rhinovirus receptor, CD54 antigenRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman ICAM-1 150-05 CHO cells 49.5 kDa 10µg 50µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human ICAM-1 500-P287 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human ICAM-1 500-P287Bbt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human ICAM-1 CATALOG # 900-K464Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human ICAM-1 CATALOG # 900-M464ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationIIFN-β Interferon betaSynonyms: Leukocyte interferon, B cell interferon, Type I interferonRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IFN-β 300-02BC CHO cells 20.0-22.4 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IFN-β 500-P32B Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IFN-β 500-P32Bbt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested55

www.peprotech.com2011-2012 IFN-γ Interferon-gammaSynonyms: Immune Interferon, type II interferon, T cell interferon, MAFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IFN-γ 300-02 E.coli 16.7 kDa 20µg 100µg 1mgMurine IFN-γ 315-05 E.coli 15.6 kDa 20µg 100µg 1mgRat IFN-γ 400-20 E.coli 15.6 kDa 20µg 100µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IFN-γ AF-300-02 E.coli 16.7 kDa N/A 100µg 1mgAdditional sizes available please inquireIPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IFN-γ 500-P32 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IFN-γ 500-P32bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IFN-γ 500-P119 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IFN-γ 500-P119bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IFN-γ 500-P122 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-rat IFN-γ 500-P122bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IFN-γ 500-P122G Goat E, WB, N 50µg 100µg 1mgBiot. anti-rat IFN-γ 500-P122Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IFN-γ 500-M90 Mouse E, WB, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IFN-γ CATALOG # 900-K27Murine IFN-γ CATALOG # 900-K98Rat IFN-γ CATALOG # 900-K109Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IFN-γ CATALOG # 900-M27Murine IFN-γ CATALOG # 900-M98ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationContinued on next page56

PEPROTECH ®www.peprotech.comIFN-γ ContinuedHuman cervical squamous cellcarcinoma (FFPE) stainedwith rabbit anti-human IFNγat 0.25 µg/mL.Tissue samples were provided by theCooperative Human Tissue Network,which is funded by the National CancerInstitute. Other investigators mayhave received specimens from the samesubjects.Photograph provided by PatsyRuegg for PeproTech.IFN-λ -1,-2 Interferon lambda-1,-2Synonyms: IFN-λ1: IL-29; IFN-λ2: IL-28ARecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IFN-λ1 300-02L E.coli 19.8 kDa 5µg 20µg 1mgHuman IFN-λ2 300-02K E.coli 19.6 kDa 5µg 20µg 1mgMurine IFN-λ2 250-33 E.coli 19.8 kDa 5µg 20µg 1mgAdditional sizes available please inquireIPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IFN-λ2 500-P247 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human IFN-λ2 500-P247bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIFN-ω Interferon-omegaSynonyms: IFN alpha II-1, IFNW1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IFN-ω 300-02J E.coli 19.9 kDa 20µg 100µg 1mgAdditional sizes available please inquire57

www.peprotech.com2011-2012 IGF-I and IGF-II Insulin-like growth factor I and IISynonyms: IGF-I: Somatamedin C, IGF-IA; IGF-II: Somatamedin ARecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IGF-I 100-11 E.coli 7.6 kDa 20µg 100µg 1mgMurine IGF-I 250-19 E.coli 7.6 kDa 10µg 50µg 1mgHuman IGF-II 100-12 E.coli 7.5 kDa 10µg 50µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IGF-I AF-100-11 E.coli 7.6 kDa N/A 100µg 1mgAdditional sizes available please inquireIPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IGF-I 500-P11 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IGF-I 500-P11bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IGF-I 500-P157G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine IGF-I 500-P157Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-human IGF-II 500-P12 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IGF-II 500-P12bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Murine IGF-I CATALOG # 900-K170ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationNormal human placenta (FFPE) stained with rabbitanti-human IGF-II at 5.0 µg/ml. Staining of epithelialcells and vessel lining cells. Photograph by PeproTech.58

PEPROTECH ®www.peprotech.comIGF-BP Insulin-like growth factor binding proteinsSynonyms: IGF-BP1: IBP-1, Placenta Protein 12 (PP12)IGF-BP2: IBP-2IGF-BP3: Growth-hormone-dependant binding proteinIGF-BP4: IBP-4, HT29-IGF-BP, colon cancer cell growth inhibitorIGF-BP5: noneIGF-BP6: IBP-6IGF-BP7: Mac25, IGFBPrP1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IGF-BP1 350-10 E.coli 25.4 kDa 5µg 25µg 1mgHuman IGF-BP2 350-06B Insect cells 31.5 kDa 5µg 20µg 1mgHuman IGF-BP3 100-08 E.coli 28.8 kDa 5µg 25µg 1mgHuman IGF-BP4 350-05B Insect cells 26.0 kDa 5µg 20µg 1mgHuman IGF-BP5 100-05 E.coli 28.6 kDa 5µg 25µg 1mgHuman IGF-BP6 350-07B Insect cells 23.0-30.0 kDa 5µg 20µg 1mgHuman IGF-BP7 350-09 E.coli 26.4 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IGF-BP1 500-P228 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human IGF-BP1 500-P228bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human IGF-BP3 500-P230 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human IGF-BP3 500-P230bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human IGF-BP5 500-P232 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human IGF-BP5 500-P232bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human IGF-BP7 500-P234 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human IGF-BP7 500-P234bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedINormal human placenta (FFPE) stained with rabbitanti-human IGF-BP3 at 2.5 µg/ml. Photographby PeproTech.59

www.peprotech.com2011-2012 IL-1α Interleukin-1 alphaISynonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous pyrogen (EP), Leukocyteendogenous mediator (LEM), Mononuclear cell factor (MCF)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-1α 200-01A E.coli 18.0 kDa 2µg 10µg 1mgMurine IL-1α 211-11A E.coli 17.9 kDa 2µg 10µg 1mgRat IL-1α 400-01A E.coli 17.7 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-1α 500-P21A Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-1α 500-P21Abt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-1α 500-P51A Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-1α 500-P51Abt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-1α 500-P180G Goat E, WB, N 50µg 100µg 1mgBiot. anti-rat IL-1α 500-P180Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-1α CATALOG # 900-K11Murine IL-1α CATALOG # 900-K82Rat IL-1α CATALOG # 900-K204ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination1.701.601.50OD (490 nm)1.401.301.201.101.000.900.800.00 0.01 0.10 1.00 10.00 100.00 1000.00Human IL-1αRat IL-1αMurine IL-1αIL-1α (pg/ml) [log scale]Bioassay analysis of human, murine, and rat IL-1α (proliferation)using mouse D10S cells.60

PEPROTECH ®www.peprotech.comIL-1β Interleukin-1 betaSynonyms: Catabolin, Lymphocyte-activating factor (LAF), Endogenous pyrogen (EP), Leukocyteendogenous mediator (LEM), Mononuclear cell factor (MCF)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-1β 200-01B E.coli 17.3 kDa 2µg 10µg 1mgMurine IL-1β 211-11B E.coli 17.5 kDa 2µg 10µg 1mgRat IL-1β 400-01B E.coli 17.3 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-1β AF-200-01B E.coli 17.3 kDa N/A 10µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine IL-1β 500-P51 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-1β 500-P51bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-1β 500-P80 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat IL-1β 500-P80bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Murine IL-1β CATALOG # 900-K47Rat IL-1β CATALOG # 900-K91Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Murine IL-1β CATALOG # 900-M47ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using Rat IL-1β ELISA development kit.61

www.peprotech.com2011-2012 IL-1RA Interleukin-1 receptor antagonistSynonyms: ICIL-1RA, IRAP, IL-1RNRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-1RΑ 200-01RA E.coli 17.2 kDa 20µg 100µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-1RA 500-P209 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-1RA 500-P209bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-1RA CATALOG # 900-K474IMini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-1RA CATALOG # 900-M474ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve usingHuman IL-1RA ELISAdevelopment Kit.62

PEPROTECH ®www.peprotech.comIL-2 Interleukin-2Synonyms: T-cell growth factor (TCGF), AldesleukinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-2 200-02 E.coli 15.4 kDa 10µg 50µg 1mgMurine IL-2 212-12 E.coli 17.2 kDa 5µg 20µg 1mgRat IL-2 400-02 E.coli 15.3 kDa 5µg 20µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-2 AF-200-02 E.coli 15.4 kDa N/A 50µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-2 500-P22 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-2 500-P22bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human IL-2 500-P22G Goat I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-2 500-P22Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine IL-2 500-P111 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-2 500-P111bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-2 500-P274 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat IL-2 500-P274bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-2 500-M02 Mouse I, E 500µgAnti-murine IL-2 500-M127 Rat E 500µgAnti-rat IL-2 500-M129 Mouse E 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-2 CATALOG # 900-K12Murine IL-2 CATALOG # 900-K108Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-2 CATALOG # 900-M12ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationHuman breast invasive ductal carcinoma (FFPE) stainedwith goat anti-human IL-2 at 0.5 µg/mL. Staining of lymphocyteswith tumor cells in the center.Tissue samples were provided by the Cooperative Human TissueNetwork, which is funded by the National Cancer Institute. Otherinvestigators may have received specimens from the same subjects.Photograph provided by Patsy Ruegg for PeproTech.63

www.peprotech.com2011-2012 sIL-2Rα soluble Interleukin-2 receptor alphaSynonyms: TAC-antigen, CD25 antigenRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sIL-2Rα 200-02R Insect cells 31.0 kDa 5µg 25µg 1mgMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAdditional sizes available please inquireAnti-human sIL-2Rα 500-M02R Mouse I, E 500µgKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIL-3 Interleukin-3Synonyms: Mast cell growth factor (MCGF), multipotential colony-stimulating factor (Multi-CSF),hematopoietic cell growth factor (HCGF), P-cell stimulation factorIRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-3 200-03 E.coli 15.0 kDa 2µg 10µg 1mgMurine IL-3 213-13 E.coli 15.1 kDa 2µg 10µg 1mgRat IL-3β 400-03 E.coli 16.3 kDa 5µg 20µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-3 AF-200-03 E.coli 15.0 kDa N/A 10µg 1mgMurine IL-3 AF-213-13 E.coli 15.1 kDa N/A 10µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-3 500-P23 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-3 500-P23bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-3 500-P53 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-3 500-P53bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-3β 500-P177G Goat E, WB, N 50µg 100µg 1mgBiot. anti-rat IL-3β 500-P177Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-3 CATALOG # 900-K13Murine IL-3 CATALOG # 900-K48ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination64

PEPROTECH ®www.peprotech.comIL-4 Interleukin-4Synonyms: BCGF, BCDF, B cell stimulating factor (BSF-1)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-4 200-04 E.coli 14.9 kDa 5µg 20µg 1mgMurine IL-4 214-14 E.coli 13.5 kDa 5µg 20µg 1mgRat IL-4 400-04 E.coli 14.0 kDa 5µg 20µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-4 AF-200-04 E.coli 14.9 kDa N/A 20µg 1mgMurine IL-4 AF-214-14 E.coli 13.5 kDa N/A 20µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-4 500-P24 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-4 500-P24bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-4 500-P54 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-4 500-P54bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-4 500-P94 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-rat IL-4 500-P94bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I= IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-4 500-M04 Mouse E, WB, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-4 CATALOG # 900-K14Murine IL-4 CATALOG # 900-K49Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-4 CATALOG # 900-M14ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination65

www.peprotech.com2011-2012 sIL-4Rα soluble Interleukin-4 receptor alphaSynonyms: CD124Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sIL-4Rα 200-04R HEK 293 cells 23.7 kDa 3µg 15µg 1mgAdditional sizes available please inquireIL-5 Interleukin-5Synonyms: EDF, BCDFII, TRFIRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-5 200-05 E.coli 26.0 kDa 2µg 10µg 1mgMurine IL-5 215-15 E.coli 26.2 kDa 5µg 25µg 1mgRat IL-5 400-05 E.coli 26.0 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-5 500-P25 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-5 500-P25bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-5 CATALOG # 900-K15Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-5 CATALOG # 900-M15ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination66

PEPROTECH ®www.peprotech.comIL-6 Interleukin-6Synonyms: 26 kDa protein, IFN-β2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-6 200-06 E.coli 20.9 kDa 5µg 20µg 1mgMurine IL-6 216-16 E.coli 21.7 kDa 2µg 10µg 1mgRat IL-6 400-06 E.coli 21.7 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-6 AF-200-06 E.coli 20.9 kDa N/A 20µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-6 500-P26 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-6 500-P26bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human IL-6 500-P26G Goat I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-6 500-P26Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine IL-6 500-P56 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-6 500-P56bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-6 500-P73 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat IL-6 500-P73bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-6 500-P73G Goat E, WB, N 50µg 100µg 1mgBiot. anti-rat IL-6 500-P73Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-6 500-M06 Mouse I, E, WB, N 500µgKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIL-6 continued on next page...67

www.peprotech.com2011-2012 IL-6 continued...ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-6 CATALOG # 900-K16Murine IL-6 CATALOG # 900-K50Rat IL-6 CATALOG # 900-K86Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-6 CATALOG # 900-M16Rat IL-6 CATALOG # 900-M86ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationIHuman cervical squamous cell carcinoma (FFPE) stained with rabbitanti-human IL-6 at 0.5 µg/ml. Staining of tumor cells andextracellular expression.Tissues samples were provided by the Cooperative Human Tissue Network, which is funded by the NCI.Other investigators may have received specimens from the same subjects.Photographs provided by Patsy Ruegg for PeproTech.sIL-6Rα soluble Interleukin-6 receptor alphaSynonyms: B-cell stimulatory factor-2 receptor, CD126Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sIL-6Rα 200-06R HEK 293 cells 37.6 kDa 5µg 20µg 1mgAdditional sizes available please inquire68

PEPROTECH ®www.peprotech.comIL-7 Interleukin-7Synonyms: Lymphopoietin 1 (LP-1), pre-B cell factorRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-7 200-07 E.coli 17.4 kDa 2µg 10µg 1mgMurine IL-7 217-17 E.coli 15.0 kDa 2µg 10µg 1mgRat IL-7 400-07 E.coli 15.0 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-7 500-P27 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-7 500-P27bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-7 500-P57 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-7 500-P57bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-7 500-M07 Mouse E, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.IHuman IL-7 CATALOG # 900-K17ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationIL-8/CXCL8 Interleukin-8Synonyms: CXCL8, MDNCF, Neutrophil activating factor (NAF), NAP-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-8 (72 a.a.) 200-08M E.coli 8.4 kDa 5µg 25µg 1mgHuman IL-8 (77 a.a.) 200-08 E.coli 8.9 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-8 500-P28 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-8 500-P28bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIL-8 continued on next page...69

www.peprotech.com2011-2012 IL-8 continued...Normal human skin (FFPE) stained with rabbitanti-human IL-8 at 0.25 µg/ml. Photographby PeproTech.Monoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-8 500-M08 Mouse E, N, WB 500µgKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-8 CATALOG # 900-K18IMini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-8 CATALOG # 900-M18ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationIL-9 Interleukin-9Synonyms: p40 cytokine, T-cell growth factor p40Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-9 200-09 E.coli 14.0 kDa 2µg 10µg 1mgMurine IL-9 219-19 E.coli 14.3 kDa 2µg 10µg 1mgRat IL-9 400-18 E.coli 14.3 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-9 500-P29 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-9 500-P29bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-9 500-P59 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-9 500-P59bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-9 CATALOG # 900-K20ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination70

PEPROTECH ®www.peprotech.comIL-10 Interleukin-10Synonyms: B-TCGF, CSIF, TGIFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-10 200-10 E.coli 18.6 kDa 2µg 10µg 1mgMurine IL-10 210-10 E.coli 18.7 kDa 2µg 10µg 1mgRat IL-10 400-19 E.coli 18.7 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-10 500-P20 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-10 500-P20bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-10 500-P60 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-10 500-P60bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IL-10 500-P139 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-rat IL-10 500-P139bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-10 500-M86 Mouse I, E, WB 500µgAnti-murine IL-10 500-M128 Rat E, WB, N 500µgAnti-rat IL-10 500-M130 Mouse E 500µgIELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-10 CATALOG # 900-K21Murine IL-10 CATALOG # 900-K53Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Murine IL-10 CATALOG # 900-M53ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination71

www.peprotech.com2011-2012 IL-11 Interleukin-11Synonyms: AGIF (Adipogenesis inhibitory factor)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-11 200-11 E.coli 19.1 kDa 2µg 10µg 1mgMurine IL-11 220-11 E.coli 19.2 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-11 500-P01 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-11 500-P01bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-11 500-M11 Mouse E, WB, N 500µgIBioassay analysis of murine IL-11(proliferation) using T11 cells.72

PEPROTECH ®www.peprotech.comIL-12 Interleukin-12Synonyms: NKSF, CTL maturation factor, Cytotoxic lymphocyte maturation factor (CLMF), TSFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-12 200-12 CHO cells 75.0 kDa 2µg 10µg 1mgMurine IL-12 210-12 CHO cells 75.0 kDa 2µg 10µg 1mgHuman IL-12 p40 200-12p40 CHO cells 40.0 kDa 2µg 10µg 1mgHuman IL-12 p80 200-12p80H Insect cells 80.0 kDa 2µg 10µg N/APolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-12 500-P154G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human IL-12 500-P154Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine IL-12 500-P155G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-12 500-P155Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-12 500-M12 Mouse E, WB 500µgAnti-murine IL-12 500-M59 Rat E, N 500µgIELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-12 CATALOG # 900-K96Murine IL-12 CATALOG # 900-K97Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-12 CATALOG # 900-M96Murine IL-12 CATALOG # 900-M97ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using Human IL-12 ELISAdevelopment kit.73

www.peprotech.com2011-2012 IL-13 Interleukin-13Synonyms: P600 (murine), NC30 (human)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-13 200-13 E.coli 12.5 kDa 2µg 10µg 1mgMurine IL-13 210-13 E.coli 12.3 kDa 2µg 10µg 1mgRat IL-13 400-16 E.coli 11.9 kDa 2µg 10µg 1mgRat IL-13 (113 a.a.) 400-16L E.coli 12.3 kDa 2µg 10µg 1mgHuman IL-13 Variant 200-13A E.coli 12.6 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-13 500-P13 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-13 500-P13bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-13 500-P178 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-13 500-P178bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-13 CATALOG # 900-K23Murine IL-13 CATALOG # 900-K207Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Murine IL-13 CATALOG # 900-M207ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination74

PEPROTECH ®www.peprotech.comIL-15 Interleukin-15Synonyms: IL-TRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-15 200-15 E.coli 12.9 kDa 2µg 10µg 1mgMurine IL-15 210-15 E.coli 13.3 kDa 2µg 10µg 1mgRat IL-15 400-24 E.coli 13.5 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-15 AF-200-15 E.coli 12.9 kDa N/A 10µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-15 500-P15 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-15 500-P15bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-15 500-P173 Rabbit E, WB, N 25µg 100µg 1mgBiot. anti-murine IL-15 500-P173bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human IL-15 500-M15 Mouse E, WB 500µgIL-16 Interleukin-16Synonyms: LCF (Lymphocyte Chemoattractant Factor)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-16 (121 a.a.) 200-16A E.coli 12.4 kDa 2µg 10µg 1mgHuman IL-16 (130 a.a.) 200-16 E.coli 13.5 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-16 AF-200-16A E.coli 12.4 kDa N/A 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-16 500-P06 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-16 500-P06bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested75

www.peprotech.com2011-2012 IL-17A/IL-17 Interleukin-17ASynonyms: CTLA-8Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-17A/IL-17 200-17 E.coli 31.0 kDa 5µg 25µg 1mgMurine IL-17 210-17 E.coli 30.0 kDa 5µg 25µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-17 AF-200-17 E.coli 31.0 kDa N/A 25µg 1mgAdditional sizes available please inquireIPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-17A 500-P07 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-17A 500-P07bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human IL-17A 500-P07G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human IL-17A 500-P07Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine IL-17A 500-P265 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine IL-17A 500-P265bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-17A/IL-17 CATALOG # 900-K84Murine IL-17 CATALOG # 900-K392Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-17A CATALOG # 900-M84Murine IL-17A CATALOG # 900-M392ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination76

PEPROTECH ®www.peprotech.comIL-17B Interleukin-17BSynonyms: IL-20, NIRFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-17B 200-28 E.coli 36.6 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-17B 500-P248 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human IL-17B 500-P248bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIL-17D Interleukin-17DSynonyms: IL-27Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-17D 200-27 E.coli 40.5 kDa 5µg 25µg 1mgAdditional sizes available please inquireIIL-17E Interleukin-17ESynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-17E 200-24 E.coli 33.8 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-17E 500-P89 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human IL-17E 500-P89bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-17E CATALOG # 900-K234Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-17E CATALOG # 900-M234ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination77

www.peprotech.com2011-2012 IL-17F Interleukin-17FSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-17F 200-25 E.coli 30.1 kDa 5µg 25µg 1mgMurine IL-17F 210-17F E.coli 30.0 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-17F 500-P90 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-17F 500-P90bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-17F CATALOG # 900-K277IELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationIL-18BP Interleukin-18 Binding ProteinPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine IL-18BP 500-P153G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-murine IL-18BP 500-P153Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested78

PEPROTECH ®www.peprotech.comIL-19 Interleukin-19Synonyms: Melanoma differentiation associated like proteinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-19 200-19 E.coli 17.9 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-19 500-P189 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human IL-19 500-P189bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIL-20 Interleukin-20Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-20 200-20 E.coli 35.2 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-20 500-P190G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human IL-20 500-P190Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-20 CATALOG # 900-K224ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using Human IL-20 ELISAdevelopment kit.79

www.peprotech.com2011-2012 IL-21 Interleukin-21Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-21 200-21 E.coli 15.4 kDa 2µg 10µg 1mgMurine IL-21 210-21 E.coli 15.0 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-21 AF-200-21 E.coli 15.4 kDa N/A 10µg 1mgAdditional sizes available please inquireIPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-21 500-P191 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-21 500-P191bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-21 500-P278 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine IL-21 500-P278bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-21 CATALOG # 900-K226ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination80

PEPROTECH ®www.peprotech.comIL-22 Interleukin-22Synonyms: IL-TIFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-22 200-22 E.coli 33.6 kDa 2µg 10µg 1mgMurine IL-22 210-22 E.coli 33.4 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-22 500-P211 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human IL-22 500-P211bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IL-22 500-P223 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IL-22 500-P223bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-22 CATALOG # 900-K246IELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination81

www.peprotech.com2011-2012 IL-23 Interleukin-23Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-23 200-23 Insect cells 53.5 kDa 2µg 10µg 1mgAdditional sizes available please inquireIL-31 Interleukin-31Synonyms: noneIRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-31 200-31 E.coli 15.8 kDa 2µg 10µg 1mgMurine IL-31 210-31 E.coli 15.9 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-31 500-P249 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human IL-31 500-P249bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-31 CATALOG # 900-K347Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-31 CATALOG # 900-M347ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination82

PEPROTECH ®www.peprotech.comIL-33 Interleukin-33Synonyms: NF-HEVRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-33 200-33 E.coli 18.0 kDa 2µg 10µg 1mgMurine IL-33 210-33 E.coli 17.5 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IL-33 500-P261 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human IL-33 500-P261bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IL-33 CATALOG # 900-K398Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human IL-33 CATALOG # 900-M398IELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationIL-34 Interleukin-34Synonyms: C16orf77Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IL-34 200-34 HEK 293 cells 52.5 kDa 2µg 10µg 1mgAdditional sizes available please inquire83

www.peprotech.com2011-2012 IP-10/CXCL10 γ-Interferon inducible protein-10Synonyms: CXCL10, crg-2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman IP-10 300-12 E.coli 8.5 kDa 5µg 25µg 1mgMurine IP-10 250-16 E.coli 8.7 kDa 5µg 25µg 1mgRat IP-10 400-33 E.coli 8.6 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human IP-10 500-P93 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human IP-10 500-P93bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine IP-10 500-P129 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine IP-10 500-P129bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat IP-10 500-P290 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat IP-10 500-P290bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedIELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human IP-10 CATALOG # 900-K39Murine IP-10 CATALOG # 900-K153Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Murine IP-10 CATALOG # 900-M153ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination84

PEPROTECH ®www.peprotech.comI-TAC/CXCL11 Interferon inducible-T cell α chemokineSynonyms: CXCL11, B-R1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman I-TAC 300-46 E.coli 8.3 kDa 5µg 20µg 1mgMurine I-TAC 250-29 E.coli 9.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human I-TAC 500-P132 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human I-TAC 500-P132bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human I-TAC CATALOG # 900-K151ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationI-J-KHuman renal tumor with parenchyma (FFPE) stained withrabbit anti-human I-TAC at 0.25 µg/mL. Staining of vessellining cells and tumor cells.Tissue samples were provided by the Cooperative Human Tissue Network,which is funded by the National Cancer Institute. Other investigators may havereceived specimens from the same subjects.Photograph provided by Patsy Ruegg for PeproTech.JE/MCP-1/CCL2 (See MCP-1)Synonyms: CCL2, MCP-1KC/CXCL1 (See GROα)Synonyms: CXCL1, GROαYeast Kex-2Synonyms: Endoproteinase Lys/Arg-ArgRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BYeast Kex-2 450-45 Insect cells 59.9 kDa 50µg 250µg 1mgAdditional sizes available please inquire85

www.peprotech.com2011-2012 KGF/FGF-7 (See FGF-7)Synonyms: FGF-7, HBGFKLF4-TATSynonyms: Kruppel-like factor-4, EZF, GKLFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman KLF4-TAT 110-08 HEK 293 cells 51.7 kDa 5µg 25µg 1mgAdditional sizes available please inquireKlothoSynonyms: αKlotho, KLAK-LRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Klotho 100-53 CHO cells 65.0-70.0 kDa 5µg 20µg 1mgAdditional sizes available please inquireLAG-1/CCL4L1 Lymphocyte activation gene-1Synonyms: CCL4L1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman LAG-1 300-58 E.coli 7.7 kDa 5µg 20µg 1mgAdditional sizes available please inquireLD78β/CCL3L1Synonyms: CCL3L1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman LD78β 300-56 E.coli 7.7 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human LD78β 500-P187G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human LD78β 500-P187Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested86

PEPROTECH ®www.peprotech.comLEC/CCL16 Liver-expressed chemokineSynonyms: CCL16, NCC-4, HCC-4, LMC, LCC-1, MTN-1, IL-10-inducible chemokineRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman LEC 300-44 E.coli 11.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human LEC 500-P125G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human LEC 500-P125Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human LEC 500-M43 Mouse E, WB, N 500µgLeptinSynonyms: Obesity protein (OB)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Leptin 300-27 E.coli 16.0 kDa 200µg 1000µg 5mgMurine Leptin 450-31 E.coli 16.2 kDa 200µg 1000µg 5mgRat Leptin 400-21 E.coli 16.2 kDa 200µg 1000µg 5mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Leptin 500-P86 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Leptin 500-P86bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine Leptin 500-P68 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-murine Leptin 500-P68bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat Leptin 500-P185G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-rat Leptin 500-P185Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedLMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human Leptin 500-M27 Mouse E, WB 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human Leptin CATALOG # 900-K90Murine Leptin CATALOG # 900-K76ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationSee next page for IHC images of anti-murine Leptin...87

www.peprotech.com2011-2012 Leptin Continued…Murine tissue 4% PFA, paraffin-embedded sections of a Trichuris muris infected mouse stainedwith rabbit anti-murine Leptin at 0.20 µg/ml. Information and photographs are courtesy of KatherineGuild and David Artis, University of Pennsylvania.LIGHTLSynonyms: TNFSF14, HVEM-LRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman LIGHT 310-09B Insect cells 21.4 kDa 3µg 15µg N/AMurine LIGHT 315-12 E.coli 20.1 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human LIGHT 500-P179 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human LIGHT 500-P179bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedLin28-TATSynonyms: CSDD1, LIN28A, ZCCHC1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Lin28-TAT 110-06 E.coli 24.4 kDa 5µg 25µg 1mgAdditional sizes available please inquireLIX/CXCL5 (See ENA-78)Synonyms: CXCL5, ENA-78 (human)88

PEPROTECH ®www.peprotech.comLungkineSynonyms: CXCL15Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine Lungkine 250-37 E.coli 16.3 kDa 5µg 20µg 1mgAdditional sizes available please inquireLymphotactin/XCL1Synonyms: XCL1, SCM-1a, ATACRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Lymphotactin 300-20 E.coli 10.0 kDa 5µg 20µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Lymphotactin 500-P40 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human Lymphotactin 500-P40bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedL-MMaspinSynonyms: SerpinB5, Protease inhibitor 5Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Maspin 130-12 E.coli 42.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Maspin 500-P270 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Maspin 500-P270bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedAnti-Human Maspin (Catalog #500-P270)Human breast lobular carcinoma in situ (FFPE) stainedwith Rabbit Anti-Human Maspin at 7.8 ng/mL. Stainingof myoepithelial cells.Tissue samples were provided by the Cooperative Human Tissue Network,which is funded by the National Cancer Institute. Other investigators may havereceived specimens from the same subjects.89

www.peprotech.com2011-2012 M-CSF Macrophage colony stimulating factorSynonyms: CSF-1, MGI-IMRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman M-CSF 300-25 E.coli 36.8 kDa 2µg 10µg 1mgMurine M-CSF 315-02 E.coli 36.4 kDa 2µg 10µg 1mgRat M-CSF 400-28 E.coli 36.2 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman M-CSF AF-300-25 E.coli 36.8 kDa N/A 10µg 1mgMurine M-CSF AF-315-02 E.coli 36.4 kDa N/A 10µg 1mgAdditional sizes available please inquireMPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human M-CSF 500-P44 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human M-CSF 500-P44bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine M-CSF 500-P62G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine M-CSF 500-P62Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Murine M-CSF CATALOG # 900-K245ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination90

PEPROTECH ®www.peprotech.comMCPs Monocyte chemotactic proteinsSynonyms: MCP-1: CCL2, JE (murine); MCP-2: CCL8, HC14; MCP-3: CCL7, MARC; MCP-4:CCL13, NCC-1; MCP-5: CCL12Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MCP-1 300-04 E.coli 8.6 kDa 5µg 20µg 1mgMurine JE/MCP-1 250-10 E.coli 13.8 kDa 2µg 10µg 1mgRat MCP-1 400-12 E.coli 14.0 kDa 2µg 10µg 1mgHuman MCP-2 300-15 E.coli 8.9 kDa 2µg 10µg 1mgMurine MCP-2 250-14 E.coli 8.5 kDa 5µg 20µg 1mgHuman MCP-3 300-17 E.coli 9.0 kDa 2µg 10µg 1mgMurine MCP-3 250-08 E.coli 8.5 kDa 2µg 10µg 1mgHuman MCP-4 300-24 E.coli 8.6 kDa 5µg 20µg 1mgMurine MCP-5 250-04 E.coli 9.3 kDa 5µg 20µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman MCP-1 AF-300-04 E.coli 8.6 kDa N/A 20µg 1mgAdditional sizes available please inquireMPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MCP-1 500-P34 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human MCP-1 500-P34bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine JE/MCP-1 500-P113 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine JE/MCP-1 500-P113bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman breast invasive ductal carcinoma (FFPE) stained withrabbit anti-human MCP-1 at 2.5 µg/ml. Tear shaped mammaryduct with tumor cells and normal cells.Tissue samples were provided by the Cooperative Human Tissue Network, which is funded bythe NCI. Other investigators may have received specimens from the same subjects.Photographs by PeproTech.MCP continued on next page...91

www.peprotech.com2011-2012 MCP continued...MPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-rat MCP-1 500-P76 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat MCP-1 500-P76bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human MCP-2 500-P35 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human MCP-2 500-P35bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine MCP-2 500-P127 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine MCP-2 500-P127bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human MCP-3 500-P37 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human MCP-3 500-P37bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human MCP-3 500-P37G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human MCP-3 500-P37Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine MCP-3 500-P116G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine MCP-3 500-P116Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-human MCP-4 500-P04 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human MCP-4 500-P04bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human MCP-4 500-P04G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human MCP-4 500-P04Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine MCP-5 500-P61 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine MCP-5 500-P61bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human MCP-1 500-M71 Mouse I, E, WB 500µgAnti-human MCP-2 500-M69 Mouse E, WB, N 500µgAnti-human MCP-3 500-M73 Mouse E, WB, N 500µgAnti-human MCP-4 500-M70 Mouse E, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells..Human MCP-1 CATALOG # 900-K31Murine JE/MCP-1 CATALOG # 900-K126Rat MCP-1 CATALOG # 900-K59Murine MCP-3 CATALOG # 900-K123Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Murine JE/MCP-1 CATALOG # 900-M126ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination92

PEPROTECH ®www.peprotech.comMDC/CCL22 Macrophage-derived chemokineSynonyms: CCL22, STCP-1, ABCD-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MDC (67 a.a.) 300-36 E.coli 8.0 kDa 5µg 20µg 1mgHuman MDC (69 a.a.) 300-36A E.coli 8.1 kDa 5µg 20µg 1mgMurine MDC 250-23 E.coli 7.8 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MDC 500-P107 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human MDC 500-P107bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine MDC 500-P176 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine MDC 500-P176bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human MDC 500-M41 Mouse E, WB 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.MMurine MDC CATALOG # 900-K197ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using Murine MDC ELISAdevelopment kit.MEC/CCL28 Mucosae-associated epithelial chemokineSynonyms: CCL28, CCK-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MEC 300-57 E.coli 12.3 kDa 5µg 20µg 1mgMurine MEC 250-30 E.coli 12.6 kDa 5µg 20µg 1mgAdditional sizes available please inquire93

www.peprotech.com2011-2012 MIA Melanoma inhibitory activitySynonyms: CD-RAP (murine and rat)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIA 130-01 E.coli 12.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIA 500-P243 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human MIA 500-P243bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman pancreas adenocarcinoma (FFPE)stained with rabbit anti-human MIA at 1.0 µg/ml.Tissue samples were provided by the Cooperative Human TissueNetwork, which is funded by the NCI. Other investigators may havereceived specimens from the same subjects.Photographs provided byPeproTech and Patsy Ruegg.MMIA-2 Melanoma inhibitory activity-2Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIA-2 130-02 E.coli 11.5 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIA-2 500-P255 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human MIA-2 500-P255bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human MIA-2 CATALOG # 900-K357ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationHuman pancreas infiltrating ductal adenocarcinoma tissue(FFPE)stained with rabbit anti-human MIA-2 at 5.0 µg/ml.Tissue samples were provided by the Cooperative Human Tissue Network, which is funded by theNCI. Other investigators may have received specimens from the same subjects.Photograph by PeproTech.94

PEPROTECH ®www.peprotech.comMidkineSynonyms: MK, NEGF-2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Midkine 450-16 E.coli 13.4 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Midkine 500-P171 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Midkine 500-P171bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human Midkine CATALOG # 900-K190ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationMIG/CXCL9 Monokine induced by interferon-γMSynonyms: CXCL9Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIG 300-26 E.coli 11.7 kDa 5µg 20µg 1mgMurine MIG 250-18 E.coli 12.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIG 500-P50 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human MIG 500-P50bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human MIG 500-M42 Mouse E, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells..Human MIG CATALOG # 900-K87Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human MIG CATALOG # 900-M87ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination95

www.peprotech.com2011-2012 MIP-1α and β Macrophage inflammatory proteins alpha and betaSynonyms: MIP-1α: CCL3, LD78αMIP-1β: CCL4, ACT-2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIP-1α 300-08 E.coli 7.8 kDa 5µg 20µg 1mgMurine MIP-1α 250-09 E.coli 7.8 kDa 2µg 10µg 1mgRat MIP-1α 400-15 E.coli 7.8 kDa 5µg 20µg 1mgHuman MIP-1β 300-09 E.coli 7.6 kDa 2µg 10µg 1mgMurine MIP-1β 250-32 E.coli 7.8 kDa 2µg 10µg 1mgRat MIP-1β 400-09 E.coli 7.8 kDa 5µg 20µg 1mgAdditional sizes available please inquireMPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIP-1α 500-P38 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human MIP-1α 500-P38bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human MIP-1α 500-P38G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human MIP-1α 500-P38Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine MIP-1α 500-P121 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine MIP-1α 500-P121bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat MIP-1α 500-P77 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat MIP-1α 500-P77bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human MIP-1β 500-P38B Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human MIP-1β 500-P38Bbt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine MIP-1β 500-P213 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine MIP-1β 500-P213bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human MIP-1α 500-M74 Mouse E, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human MIP-1α CATALOG # 900-K35Murine MIP-1α CATALOG # 900-K125Rat MIP-1α CATALOG # 900-K75Murine MIP-1β CATALOG # 900-K278Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human MIP-1α CATALOG # 900-M125Murine MIP-1β CATALOG # 900-M278ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationSee next page for standard curve for Human MIP-1 alpha ELISA development kit...96

PEPROTECH ®www.peprotech.comMIP-1α and β Continued…Standard curve using the Human MIP-1 alphaELISA development kit.MIP-1γ/CCL9/10 Macrophage inflammatory protein gammaSynonyms: CCL9/10, MRP-2, CCF18Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine MIP-1γ 250-12 E.coli 11.6 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine MIP-1γ 500-P117 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine MIP-1γ 500-P117bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMMurine MIP-1γ induces chemotaxis ofpurified human monocytes.MIP-2/CXCL2 (See GROβ)Synonyms: CXCL2, GROβvMIP-2 viral Macrophage inflammatory protein-2Synonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BvMIP-2 350-03 E.coli 7.9 kDa 10µg 50µg 1mgAdditional sizes available please inquire97

www.peprotech.com2011-2012 MIP-3/CCL23 Macrophage inflammatory protein-3Synonyms: CCL23, MPIF-1, Ck-β8Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIP-3 300-29 E.coli 11.3 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIP-3 500-P124 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human MIP-3 500-P124bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMIP-3α/CCL20 Macrophage inflammatory protein-3 alphaMSynonyms: CCL20, LARC, Exodus-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIP-3α 300-29A E.coli 8.0 kDa 5µg 20µg 1mgMurine MIP-3α 250-27 E.coli 7.9 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIP-3α 500-P95A Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human MIP-3α 500-P95Abt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human MIP-3α 500-M28 Mouse E, WB 500µghCCR6/HEK293 Migration (Mean No./HPF±std)400350Binding Mediumh MIP-3a3002502001501005000 0.1 1 10 100 1000Concentration of Chemokines (ng/ml)Human MIP-3α induces chemotaxis of HEK293 cellstransfected with human CCR6.98

PEPROTECH ®www.peprotech.comMIP-3β/CCL19 Macrophage inflammatory protein-3 betaSynonyms: CCL19, ELC, Exodus-3Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIP-3β 300-29B E.coli 8.8 kDa 5µg 20µg 1mgMurine MIP-3β 250-27B E.coli 9.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIP-3β 500-P95B Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human MIP-3β 500-P95Bbt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human MIP-3β 500-M29 Mouse E 500µgRepresentative Western Transfer (blot) analysis ofhuman MIP-3α using anti-human MIP-3β at 0.20µgml.kDa14860M4230221764MIP-4/CCL18 Macrophage inflammatory protein-4Synonyms: CCL18, PARC, DC-CK1, AMAC-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIP-4 300-34 E.coli 7.8 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIP-4 500-P108 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human MIP-4 500-P108bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested99

www.peprotech.com2011-2012 MIP-5/CCL15 Macrophage inflammatory protein-5Synonyms: CCL15, HCC-2, Lkn-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MIP-5 300-43 E.coli 10.1 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human MIP-5 500-P123G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human MIP-5 500-P123Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMMP-1 Matrix metalloproteinase-1Synonyms: Fibroblast collagenase, Interstitial CollagenaseMRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MMP-1 420-01 E.coli 42.7 kDa 2µg 10µg 1mgAdditional sizes available please inquireMMP-2 Matrix metalloproteinase-2Synonyms: Gelatinase A, TBE-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MMP-2 420-02 E.coli 62.1 kDa 2µg 10µg 1mgAdditional sizes available please inquireMMP-3 Matrix metalloproteinase-3Synonyms: Stromelysin-1, SL-1, Transin-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman MMP-3 420-03 E.coli 42.8 kDa 2µg 10µg 1mgMycoplasma Arginine DeiminaseSynonyms: ADIRecombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BMycoplasma Arginine Deiminase 150-12 E.coli 46.4 kDa 5µg 20µg 1mgAdditional sizes available please inquire100

PEPROTECH ®www.peprotech.comMyostatinSynonyms: GDF-8Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Myostatin 120-00 E.coli 25.0 kDa 2µg 10µg 1mgAdditional sizes available please inquireMyostatin PropeptideSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Myostatin Propeptide 120-12 E.coli 27.8 kDa 5µg 25µg 1mgAdditional sizes available please inquireNanogM-NSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Nanog 120-21 E.coli 34.7 kDa 5µg 20µg 1mgHuman Nanog-TAT 120-21B E.coli 36.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Nanog 500-P236 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Nanog 500-P236bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedAnti-Human Nanog (Catalog #500-P236)Human prostate malignant adenocarcinoma (FFPE)stained with Rabbit Anti-Human Nanog at 0.5 µg/mL.Staining of tumor cells.Tissue samples were provided by the Cooperative Human Tissue Network,which is funded by the National Cancer Institute. Other investigators may havereceived specimens from the same subjects.101

www.peprotech.com2011-2012 NAP-2/CXCL7 Neutrophil activating protein-2Synonyms: CXCL7, PBP (parent molecule), CTAP-III (precursor)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman NAP-2 300-14 E.coli 7.6 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human NAP-2 500-P03 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human NAP-2 500-P03bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human NAP-2 500-P03G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human NAP-2 500-P03Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human NAP-2 500-M33 Mouse E 500µgNELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human NAP-2 CATALOG # 900-K40ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationNeuritinSynonyms: CPG15, NRN1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Neuritin 450-36D E.coli 19.4 kDa 5µg 20µg 1mgAdditional sizes available please inquireNeuropoietinSynonyms: NPO, NPRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine Neuropoietin 250-25B E.coli 19.8 kDa 5µg 25µg 1mgAdditional sizes available please inquire102

PEPROTECH ®www.peprotech.comNeuroserpinSynonyms: Serpin I1, Protease inhibitor 12Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Neuroserpin 130-14 E.coli 44.6 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Neuroserpin 500-P271 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Neuroserpin 500-P271bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedNeurturinSynonyms: NTN, NRTNRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Neurturin 450-11 E.coli 23.6 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Neurturin 500-P102 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Neurturin 500-P102bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedN103

www.peprotech.com2011-2012 β-NGF beta-Nerve growth factorSynonyms: NGF-betaRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman β-NGF 450-01 E.coli 27.0 kDa 5µg 20µg 1mgMurine β-NGF 450-34 E.coli 27.0 kDa 5µg 20µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman β-NGF AF-450-01 E.coli 27. 0 kDa N/A 20µg 1mgAdditional sizes available please inquireNPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human β-NGF 500-P85 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human β-NGF 500-P85bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human β-NGF 500-M85 Mouse E, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human β-NGF CATALOG # 900-K60ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination104

PEPROTECH ®www.peprotech.comNNT-1/BCSF-3 Novel neurotrophin-1/B-cell stimulating factor-3Synonyms: Cardiotrophin-like cytokineRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman NNT-1/BCSF-3 450-18 E.coli 22.4 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human NNT-1/BCSF-3 500-P186 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human NNT-1/BCSF-3 500-P186bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedNOGGINSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman NOGGIN 120-10C HEK 293 cells 28.0-33.0 kDa 5µg 20µg 1mgMurine NOGGIN 250-38 E.coli 46.4 kDa 5µg 20µg 1mgAdditional sizes available please inquireNNOV Nephroblastoma overexpressed geneSynonyms: CCN3Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman NOV 120-26 E.coli 36.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human NOV 500-P257 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human NOV 500-P257bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human NOV CATALOG # 900-K338ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination105

www.peprotech.com2011-2012 NP-1 Neutrophil Peptide-1Synonyms: alpha-defensin-1, HNP-1, CryptdinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman NP-1 300-42 E.coli 3.4 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human NP-1 500-P126G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human NP-1 500-P126Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedNT-3 Neurotrophin-3Synonyms: Neurotrophic Factor, Nerve growth factor-2 (NGF-2), HGNFNRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman NT-3 450-03 E.coli 27.2 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human NT-3 500-P82 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human NT-3 500-P82bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human NT-3 500-P82G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human NT-3 500-P82Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedNT-4 Neurotrophin-4Synonyms: Neurotrophic 4/5 (NT-4/NT-5)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman NT-4 450-04 E.coli 28.1 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human NT-4 500-P83G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human NT-4 500-P83Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human NT-4 500-M24 Mouse E 500µg106

PEPROTECH ®www.peprotech.comOct4-TATSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Oct4-TAT 110-04H HEK 293 cells 41.3 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Oct4-TAT 500-P289 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Oct4-TAT 500-P289bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedOncostatin MSynonyms: OSMRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Oncostatin M (227 a.a.) 300-10 E.coli 26.0 kDa 2µg 10µg 1mgHuman Oncostatin M (209 a.a.) 300-10T E.coli 23.9 kDa 2µg 10µg 1mgRat Oncostatin M 400-36 E.coli 24.4 kDa 2µg 10µg 1mgAdditional sizes available please inquireOPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Oncostatin M 500-P30 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human Oncostatin M 500-P30bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedOsteopontinSynonyms: Bone sialoprotein 1, Secreted phosphoprotein 1, SPP-1, Nephropontin, UropontinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Osteopontin 120-35 HEK 293 cells 60.0-65.0 kDa 10µg 50µg 1mgAdditional sizes available please inquire107

www.peprotech.com2011-2012 OsteoprotegerinSynonyms: TNFRSF11B, OPG, OCIF (Osteoclastogenesis inhibitory factor),TR1 (TNF receptor like protein-1)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Osteoprotegerin (OPG) 450-14 E.coli 20.0 kDa 10µg 50µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human OPG 500-P149 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human OPG 500-P149bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedOHuman breast invasive ductal carcinoma (FFPE) stainedwith rabbit anti-human OPG at 5.0 µg/ml.Tissue samples were provided by the Cooperative Human Tissue Network, which is fundedby the NCI. Other investigators may have received specimens from the same subjects.Photograph by PeproTech.OTORSynonyms: Otoraplin, MIALRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman OTOR 130-03 E.coli 12.7 kDa 5µg 20µg 1mgAdditional sizes available please inquiresOX40 LigandSynonyms: sOX40L, Glycoprotein Gp34, CD252 antigen, TXGP1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sOX40L 310-28 Insect cells 15.5-25.0 kDa 2µg 10µg 1mgAdditional sizes available please inquire108

PEPROTECH ®www.peprotech.comp16-INK4aSynonyms: Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, CDK4I,p16INK4A, Multiple tumor suppressor 1, MTS-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman p16-INK4a 110-02 E.coli 16.5 kDa 5µg 20µg 1mgHuman p16-INK4a-TAT 110-02T E.coli 18.0 kDa 5µg 25µg 1mgPAF-AHAdditional sizes available please inquireSynonyms: PAF acetylhydrolase, PAF 2-acylhydrolase, LDL-associated phopholipase A2, LDL-PLA (2),2-acetyl-alkylglycerophosphocholine esterase, 1-alkyl-2-acetylglycerophosphocholine esteraseRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PAF-AH 140-10 HEK 293 cells 47.0-55.0 kDa 5µg 20µg 1mgAdditional sizes available please inquirePAI-1 Plasminogen Activator Inhibitor-1Synonyms: Serpin E1PRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PAI-1 140-04 E.coli 42.7 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human PAI-1 500-P260 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human PAI-1 500-P260bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human PAI-1 CATALOG # 900-K383ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationPAI-2 Plasminogen Activator Inhibitor-2Synonyms: Serpin B2, Urokinase inhibitor, Monocyte Arg-serpinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PAI-2 140-06 E.coli 46.5 kDa 2µg 10µg 1mgAdditional sizes available please inquire109

www.peprotech.com2011-2012 PDGF AA, AB, BB, CC Platelet-derived growth factorSynonyms: Glioma-derived growth factor (GDGF), Osteosarcoma-derived growth factor (ODGF)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PDGF-AA 100-13A E.coli 28.5 kDa 2µg 10µg 1mgMurine PDGF-AA 315-17 E.coli 28.8 kDa 2µg 10µg 1mgHuman PDGF-AB 100-00AB E.coli 25.5 kDa 2µg 10µg 1mgHuman PDGF-BB 100-14B E.coli 24.3 kDa 2µg 10µg 1mgMurine PDGF-BB 315-18 E.coli 24.6 kDa 2µg 10µg 1mgHuman PDGF-CC 100-00CC E.coli 25.0 kDa 5µg 20µg 1mgAdditional sizes available please inquirePAnimal-Free Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PDGF-BB AF-100-14B E.coli 24.3 kDa N/A 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human PDGF-AA 500-P46 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human PDGF-AA 500-P46bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human PDGF-BB 500-P47 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human PDGF-BB 500-P47bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human PDGF-BB CATALOG # 900-K04ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationNormal human skin (FFPE) stainedwith rabbit anti-human PDGF-AAat 1.0 µg/ml. Photographs providedby Patsy Ruegg for PeproTech.Normal human skin (FFPE)stained with rabbit anti-humanPDGF-BB at 1.0 µg/ml.Granular staining of the sweatgland epithelial cells in the dermis.Photograph by PeproTech.110

PEPROTECH ®www.peprotech.comPECAM-1Synonyms: Platelet endothelial cell adhesion molecule, CD31 antigen, EndoCamRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PECAM-1 150-06 HEK 293 cells 80.0-95.0 kDa 10µg 50µg 1mgAdditional sizes available please inquirePEDF Pigment Epithelium-Derived FactorSynonyms: Serpin F1, EPC-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PEDF 130-13 E.coli 44.5 kDa 5µg 20µg 1mgAdditional sizes available please inquirePersephinSynonyms: PSP, PSPNRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Persephin 450-12 E.coli 20.6 kDa 5µg 20µg 1mgMurine Persephin 450-35 E.coli 20.6 kDa 5µg 20µg 1mgAdditional sizes available please inquirePPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Persephin 500-P138 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Persephin 500-P138bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedPF-4/CXCL4 Platelet factor-4Synonyms: CXCL4, Oncostatin A, IroplactRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PF-4 300-16 E.coli 7.8 kDa 5µg 20µg 1mgMurine PF-4 250-39 E.coli 8.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human PF-4 500-P05 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human PF-4 500-P05bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested111

www.peprotech.com2011-2012 PleiotrophinSynonyms: PTN, Heparin affin regulatory protein (HARP), Heparin-binding growth factor-8 (HBGF8),Osteoblast-specific factor (OSF-1)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Pleiotrophin 450-15 E.coli 15.4 kDa 5µg 20µg 1mgAdditional sizes available please inquirePlGF-1 Placenta growth factor-1Synonyms: PGFPRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PlGF-1 100-06 E.coli 29.7 kDa 5µg 25µg 1mgAdditional sizes available please inquireAnimal-Free Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PlGF-1 AF-100-06 E.coli 29.7 kDa N/A 25µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human PlGF-1 500-P226 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human PlGF-1 500-P226bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human PlGF-1 CATALOG # 900-K307ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using Human PlGF-1ELISA development kit.112

PEPROTECH ®www.peprotech.comPlGF-2 Placenta growth factor-2Synonyms: PGFLRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PlGF-2 100-56 E.coli 34.0 kDa 5µg 25µg 1mgAdditional sizes available please inquirePlGF-3 Placenta growth factor-3Synonyms: PGFLRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PlGF-3 100-57 E.coli 22.7 kDa 5µg 25µg 1mgAdditional sizes available please inquirePProkineticin-2Synonyms: PK2, Protein Bv8 homologRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Prokineticin-2 100-46 E.coli 8.8 kDa 5µg 20µg 1mgAdditional sizes available please inquire113

www.peprotech.com2011-2012 ProlactinSynonyms: Mammotropin, luterotropic hormone, lutetropinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Prolactin 100-07 E.coli 23.0 kDa 10µg 50µg 1mgMurine Prolactin 315-16 E.coli 22.5 kDa 10µg 50µg 1mgRat Prolactin 400-27 E.coli 22.6 kDa 10µg 50µg 1mgAdditional sizes available please inquirePTHrP Parathyroid hormone-related proteinSynonyms: nonePRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman PTHrP 100-09 E.coli 9.8 kDa 10µg 50µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human PTHrP 500-P276 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human PTHrP 500-P276bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested114

PEPROTECH ®www.peprotech.comsRANKL soluble Receptor activator of NFkB ligandSynonyms: TNFSF11, TRANCE (TNF-related activation-induced cytokine), OPGL (Osteoprotegerinligand), ODF (Osteoclast differentiation factor)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sRANKL 310-01 E.coli 20.0 kDa 2µg 10µg 1mgMurine sRANKL 315-11 E.coli 19.4 kDa 2µg 10µg 1mgRat sRANKL 400-30 E.coli 19.6 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sRANKL 500-P133 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human sRANKL 500-P133bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human sRANKL 500-P133G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human sRANKL 500-P133Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine sRANKL 500-P63 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine sRANKL 500-P63bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human sRANKL 500-M46 Mouse E 500µgRELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human sRANKL CATALOG # 900-K142Murine sRANKL CATALOG # 900-K233ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationHuman metastatic carcinoma of lymph node (FFPE) from breast tissue stained withrabbit anti-human sRANKL at 0.25 µg/ml. Staining of membranous cells located in the germinal center.Tissue samples were provided by the Cooperative Human Tissue Network, which is funded by the NCI. Other investigators may have receivedspecimens from the same subjects.Photographs by PeproTech.115

www.peprotech.com2011-2012 sRANK Receptor soluble RANK ReceptorSynonyms: TNFRSF11A, TRANCE Receptor (TNF-related activation-induced cytokine receptor), ODAR(Osteoclast differentiation and activation receptor), ODFR (Osteoclast differentiation factor receptor)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sRANK Receptor 310-08 E.coli 19.3 kDa 20µg 100µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sRANK Receptor 500-P144 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human sRANK Receptor 500-P144bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedRHuman breast invasive ductal carcinoma (FFPE) stained withrabbit anti-human sRANK receptor at 1.0 µg/ml.Tissue samples were provided by the Cooperative Human Tissue Network, which is fundedby the NCI. Other investigators may have received specimens from the same subjects.Photograph by PeproTech.116

PEPROTECH ®www.peprotech.comRANTES Regulated upon activation normal T cell expressed sequenceSynonyms: CCL5, SIS-deltaRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman RANTES 300-06 E.coli 7.8 kDa 5µg 20µg 1mgMurine RANTES 250-07 E.coli 7.8 kDa 5µg 20µg 1mgRat RANTES 400-13 E.coli 7.9 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human RANTES 500-P36 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human RANTES 500-P36bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine RANTES 500-P118 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine RANTES 500-P118bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat RANTES 500-P78 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-rat RANTES 500-P78bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human RANTES 500-M75 Mouse E, N 500µgRELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human RANTES CATALOG # 900-K33Murine RANTES CATALOG # 900-K124Rat RANTES CATALOG # 900-K72Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human RANTES CATALOG # 900-M33ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationHuman breast invasive ductalcarcinoma (FFPE) stained with rabbitanti-human RANTES at 2.0 µg/ml.Membrane staining on infiltratingtumor cells.Tissue samples were provided by theCooperative Human Tissue Network, which is fundedby the NCI. Other investigators may have receivedspecimens from the same subjects.Photographs by PeproTech.117

www.peprotech.com2011-2012 Relaxin-2Synonyms: H2 relaxin, RLN2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Relaxin-2 130-15 E.coli 6.0 kDa 5µg 25µg 1mgAdditional sizes available please inquireRelaxin-3Synonyms: H3 relaxin, Insulin-like peptide-7, INSL7Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Relaxin-3 130-10 E.coli 5.5 kDa 5µg 25µg 1mgAdditional sizes available please inquireRRELMα Resistin-like alphaSynonyms: Cysteine-rich secreted protein FIZZ1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine RELMα 450-26 E.coli 9.5 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine RELMα 500-P214 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-murine RELMα 500-P214bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMurine cecum tissue (4% PFA, paraffin-embedded sectionswith positive cells infiltrating the Lamina Propia of a Trichurismuris infected mouse) stained with rabbit anti-murine RELMαat 4.0 ng/ml. Information and photograph are courtesy ofKatherine Guild and David Artis, University of Pennsylvania.118

PEPROTECH ®www.peprotech.comRELMβ Resistin-like betaSynonyms: Cysteine-rich secreted protein FIZZ2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman RELMβ 450-22 E.coli 19.0 kDa 5µg 25µg 1mgMurine RELMβ 450-26B E.coli 18.0 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human RELMβ 500-P217 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human RELMβ 500-P217bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine RELMβ 500-P215 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-murine RELMβ 500-P215bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMurine cecum tissue (4% PFA, paraffin-embedded sectionswith positive goblet cells of a Trichuris muris infected mouse)stained with rabbit anti-murine RELMβ at 0.33 ng/ml. Informationand photograph are courtesy of Katherine Guild and David Artis,University of Pennsylvania.RRELMγ Resistin-like gammaSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine RELMγ 450-26G E.coli 18.6 kDa 5µg 25µg 1mgAdditional sizes available please inquire119

www.peprotech.com2011-2012 ResistinSynonyms: FIZZ3, Adipose tissue-specific secretory factor, ADSFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Resistin 450-19 E.coli 19.5 kDa 5µg 25µg 1mgMurine Resistin 450-28 E.coli 20.2 kDa 5µg 25µg 1mgRat Resistin 400-35 E.coli 20.2 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Resistin 500-P183G Goat I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Resistin 500-P183Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine Resistin 500-P182G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-murine Resistin 500-P182Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedRMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human Resistin 500-M91 Mouse I, E, WB 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human Resistin CATALOG # 900-K235ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using human ResistinELISA development kit.120

PEPROTECH ®www.peprotech.comSCF Stem cell factorSynonyms: c-Kit Ligand, Mast cell growth factor (MGF), Steel factor (SF)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman SCF 300-07 E.coli 18.4 kDa 2µg 10µg 1mgMurine SCF 250-03 E.coli 18.3 kDa 2µg 10µg 1mgRat SCF 400-22 E.coli 18.4 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman SCF AF-300-07 E.coli 18.4 kDa N/A 10µg 1mgMurine SCF AF-250-03 E.coli 18.3 kDa N/A 10µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human SCF 500-P48 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human SCF 500-P48bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human SCF 500-P48G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human SCF 500-P48Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine SCF 500-P71 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine SCF 500-P71bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat SCF 500-P202 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat SCF 500-P202bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedSMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human SCF 500-M44 Mouse E, WB 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human SCF CATALOG # 900-K34Murine SCF CATALOG # 900-K78Rat SCF CATALOG # 900-K258ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationBioassay analysis of human SCF (proliferation)using human TF-1 cells.121

www.peprotech.com2011-2012 SCGF-α and β Stem cell growth factor alpha and betaSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman SCGF-α 100-22A E.coli 33.9 kDa 2µg 10µg 1mgHuman SCGF-β 100-22B E.coli 25.0 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human SCGF-β 500-P99G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human SCGF-β 500-P99Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedSDF-1α and β/CXCL12 Stromal-cell derived factor-1 alpha and betaSynonyms: CXCL12, PBSFSRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman SDF-1α 300-28A E.coli 8.0 kDa 2µg 10µg 1mgMurine SDF-1α 250-20A E.coli 7.9 kDa 2µg 10µg 1mgRat SDF-1α 400-32A E.coli 7.9 kDa 2µg 10µg 1mgHuman SDF-1β 300-28B E.coli 8.5 kDa 2µg 10µg 1mgMurine SDF-1β 250-20B E.coli 8.5 kDa 2µg 10µg 1mgRat SDF-1β 400-32B E.coli 8.4 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human SDF-1α 500-P87A Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human SDF-1α 500-P87Abt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine SDF-1α 500-P164G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine SDF-1α 500-P164Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-human SDF-1β 500-P87BG Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human SDF-1β 500-P87BGbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman colorectal adenocarcinoma (FFPE) stainedwith rabbit anti-human SDF-1α at 0.5 µg/mL.Tissue samples were provided by the Cooperative Human TissueNetwork, which is funded by the National Cancer Institute. Other investigatorsmay have received specimens from the same subjects.Photograph provided by Patsy Ruegg for PeproTech.122

PEPROTECH ®www.peprotech.comSF20Synonyms: IL-25Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BMurine SF20 210-25 E.coli 15.8 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-murine SF20 500-P259 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-murine SF20 500-P259bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedSlit2-NSynonyms: Slit homology 2 protein, SLIL3Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Slit2-N 150-11 HEK 293 cells 120.0-140.0 kDa 5µg 25µg 1mgAdditional sizes available please inquireSSonic HedgehogSynonyms: sHH, HHG-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Sonic Hedgehog (SHH) 100-45 E.coli 20.0 kDa 5µg 25µg 1mgAdditional sizes available please inquireSox2Synonyms: Sex determinining region Y (SRY)-box 2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Sox2 110-03 E.coli 34.3 kDa 5µg 25µg 1mgHuman Sox2-TAT 110-03T E.coli 35.9 kDa 5µg 25µg 1mgAdditional sizes available please inquire123

www.peprotech.com2011-2012 SPARC/OsteonectinSynonyms: Secreted protein acidic and rich in cysteine, BM-40, ONRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman SPARC/Osteonectin 120-36 CHO cells 32.0 kDa 10µg 50µg 1mgAdditional sizes available please inquireTACI Transmembrane activator and CAML interactorSynonyms: TNFRSF13BS-TRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TACI 310-17 E.coli 17.8 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TACI 500-P166G Goat E, WB, NA 50µg 100µg 1mgBiot. anti-human TACI 500-P166Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human TACI CATALOG # 900-K216ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination124

PEPROTECH ®www.peprotech.comTAFA-2Synonyms: Chemokine-like protein TAFA-2, FAM19A2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TAFA-2 300-63 E.coli 11.2 kDa 5µg 20µg 1mgAdditional sizes available please inquireTARC/CCL17 Thymus activation regulation chemokineSynonyms: CCL17, ABCD-2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TARC 300-30 E.coli 8.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TARC 500-P97 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human TARC 500-P97bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedTTECK/CCL25 Thymus-expressed chemokineSynonyms: CCL25Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TECK 300-45 E.coli 14.2 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TECK 500-P134 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human TECK 500-P134bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human TECK 500-M48 Mouse E, WB, N 500µg125

www.peprotech.com2011-2012 TFF TreFoil FactorsSynonyms: TFF-1: pS2 protein, HP1.A, Breast cancer estrogen-inducible protein, PNR2TFF-2: Spasmolytic polypeptide (SP), SpasmolysinTFF-3: Intestinal trefoil, ITF, TFIRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TFF1 300-60 E.coli 8.2 kDa 5µg 20µg 1mgHuman TFF2 300-59 E.coli 12.0 kDa 5µg 20µg 1mgHuman TFF3 300-61 E.coli 13.2 kDa 5µg 20µg 1mgAdditional sizes available please inquireTGF-α Transforming growth factor alphaSynonyms: Sarcoma growth factor, TGF-type I, ETGFTRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TGF-α 100-16A E.coli 5.5 kDa 20µg 100µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TGF-α 500-P16 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human TGF-α 500-P16bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedHuman breast invasive ductal carcinoma(FFPE) stained with rabbit anti-humanTGF-α at 0.5 µg/ml.Tissue samples were provided by the Cooperative Human TissueNetwork, which is funded by the NCI. Other investigators mayhave received specimens from the same subjects.Photographs by PeproTech.126

PEPROTECH ®www.peprotech.comTGF-β1,2 and 3 Transforming growth factor beta1, 2 and 3Synonyms: TGF-β1: Differentiation inhibiting factor, cartilage-inducing factorTGF-β2: Glioblastoma-derived T-cell suppressor factor, BSC-1, Cetermin, PolyerginTGF-β3: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TGF-β1 100-21 HEK 293 cells 25.0 kDa 1µg 5µg 1mgHuman TGF-β1 100-21C CHO cells 25.0 kDa 1µg 5µg 1mgHuman TGF-β2 100-35 Insect cells 25.0 kDa 1µg 5µg 1mgHuman TGF-β2 100-35B HEK 293 cells 25.0 kDa 1µg 5µg 1mgHuman TGF-β3 100-36E E.coli 25.0 kDa 2µg 10µg 1mgAdditional sizes available please inquireMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human TGF-β1 500-M66 Mouse I, E, WB 500µgKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedThrombomodulinSynonyms: CD141, BDCA-3, THBD, TMRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Thrombomodulin 100-58 HEK 293 cells 51.4 kDa 2µg 10µg 1mgAdditional sizes available please inquireTTIGARSynonyms: TP53-induced glycolysis and apoptosis regulatorRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TIGAR 150-14 E.coli 29.9 kDa 5µg 25µg 1mgHuman TIGAR-TAT 150-14T E.coli 31.6 kDa 5µg 25µg 1mgAdditional sizes available please inquire127

www.peprotech.com2011-2012 TIMP-1 Tissue inhibitor of metalloproteinases 1Synonyms: Fibroblast collagenase inhibitor; Erythroid-potentiating activityRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TIMP-1 410-01 E.coli 20.6 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TIMP-1 500-P280 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human TIMP-1 500-P280bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human TIMP-1 CATALOG # 900-K438TMini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human TIMP-1 CATALOG # 900-M438ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationAnti-Human TIMP-1 (Catalog #500-P280) *Human breast invasive ductal carcinoma (FFPE) stainedwith Rabbit Anti-Human TIMP-1 at 0.100 µg/mL.Staining of tumor cells.Tissue samples were provided by the Cooperative Human Tissue Network, whichis funded by the National Cancer Institute. Other investigators may have receivedspecimens from the same subjects.TIMP-2 Tissue inhibitor of metalloproteinases 2Synonyms: CSC-21KRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TIMP-2 410-02 E.coli 21.8 kDa 2µg 10µg 1mgAdditional sizes available please inquire128

PEPROTECH ®www.peprotech.comTL-1ASynonyms: TNFSF15, VEGIRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TL-1A 310-23 E.coli 22.0 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TL-1A 500-P240 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human TL-1A 500-P240bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human TL-1A CATALOG # 900-K290ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationTTLR-3 Toll-like receptor 3Synonyms: CD283 antigenRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TLR-3 160-01 HEK 293 cells 77.0 kDa 5µg 25µg 1mgAdditional sizes available please inquire129

www.peprotech.com2011-2012 TNF-α Tumor necrosis factor alphaSynonyms: TNFSF1A, TNFSF2, cachectin, differentiation-inducing factor (DIF), necrosin, cytotoxinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TNF-α 300-01A E.coli 17.4 kDa 10µg 50µg 1mgMurine TNF-α 315-01A E.coli 17.3 kDa 5µg 20µg 1mgRat TNF-α 400-14 E.coli 17.3 kDa 5µg 20µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman TNF-α AF-300-01A E.coli 17.4 kDa N/A 50µg 1mgAdditional sizes available please inquireTPolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TNF-α 500-P31A Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human TNF-α 500-P31Abt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human TNF-α 500-P31AG Goat I, E, WB, N 50µg 100µg 1mgBiot. anti-human TNF-α 500-P31AGbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine TNF-α 500-P64 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine TNF-α 500-P64bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-murine TNF-α 500-P64G Goat E, WB, N 50µg 100µg 1mgBiot. anti-murine TNF-α 500-P64Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-rat TNF-α 500-P72 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat TNF-α 500-P72bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human TNF-α 500-M26 Mouse I, E, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human TNF-α CATALOG # 900-K25Murine TNF-α CATALOG # 900-K54Rat TNF-α CATALOG # 900-K73Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human TNF-α CATALOG # 900-M25Murine TNF-α CATALOG # 900-M54ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationSee next page for IHC images of anti-human TNF-α130

PEPROTECH ®www.peprotech.comTNF-α Continued…Human breast invasive ductal carcinoma (FFPE) stained withrabbit anti-human TNF-α at 0.5 µg/ml.Tissue samples were provided by the Cooperative Human Tissue Network, which is fundedby the NCI. Other investigators may have received specimens from the same subjects.Photograph by PeproTech.TNF-β Tumor necrosis factor betaSynonyms: TNFSF1, TNFSF1B, Lymphotoxin alpha (LT-α)Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TNF-β 300-01B E.coli 18.6 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TNF-β 500-P31B Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human TNF-β 500-P31Bbt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedTsTNF Receptor Type I soluble TNF Receptor Type ISynonyms: TNFRSF1A, TNFAR, TNF-R55, TNFR60, p55, CD120aRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sTNF Receptor Type I 310-07 E.coli 18.3 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sTNF Receptor Type I 500-P143 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human sTNF Receptor Type I 500-P143bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedBioassay analysis of human sTNF Receptor Type I.Determined by its inhibitory effect for the TNF-αmediated cytotoxicity in murine L929 cells.131

www.peprotech.com2011-2012 sTNF Receptor Type II soluble TNF Receptor Type IISynonyms: TNFRSF1B, p75, TNFR75, CD120b, TNFR80, p80, TNFR2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sTNF Receptor Type II 310-12 E.coli 18.9 kDa 5µg 20µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sTNF Receptor Type II 500-P168 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-human sTNF Receptor Type II 500-P168bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedTPO ThrombopoietinSynonyms: Megakaryocyte colony-stimulating factor, c-MPL ligand, MGDFTRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TPO 300-18 E.coli 18.6 kDa 2µg 10µg 1mgMurine TPO 315-14 E.coli 18.7 kDa 2µg 10µg 1mgRat TPO 400-34 E.coli 18.7 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman TPO AF-300-18 E.coli 18.6 kDa N/A 10µg 1mgRat TPO AF-400-34 E.coli 18.7 kDa N/A 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TPO 500-P49G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human TPO 500-P49Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human TPO CATALOG # 900-K44ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationStandard curve using human TPOELISA development kit.132

PEPROTECH ®www.peprotech.comsTRAIL/Apo2L soluble TNF-related apoptosis inducing ligandSynonyms: TNFSF10, Apo2 ligand, TL2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sTRAIL/Apo2L 310-04 E.coli 19.6 kDa 10µg 50µg 1mgMurine sTRAIL 315-19 E.coli 20.0 kDa 10µg 50µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human sTRAIL/Apo2L 500-P135 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human sTRAIL/Apo2L 500-P135bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human sTRAIL/Apo2L 500-M49 Mouse E 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human sTRAIL/Apo2L CATALOG # 900-K141TELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationHuman metastatic carcinoma of lymph node from breasttissue (FFPE) stained with rabbit anti-human sTRAIL/Apo2L at 0.25 µg/ml.Tissue samples were provided by the Cooperative Human Tissue Network,which is funded by the NCI. Other investigators may have received specimensfrom the same subjects.Photograph by PeproTech.sTRAIL Receptor-1/DR4 soluble TRAIL Receptor-1Synonyms: TNFRSF10A, DR4, Apo2Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sTRAIL Receptor-1/DR4 310-18 E.coli 22.7 kDa 10µg 50µg 1mgAdditional sizes available please inquire133

www.peprotech.com2011-2012 sTRAIL Receptor-2/DR5 soluble TRAIL Receptor-2Synonyms: TNFRSF10B, DR5, KILLER, TRICK2A, TRICK2BRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman sTRAIL Receptor-2/DR5 310-19 E.coli 14.9 kDa 10µg 50µg 1mgAdditional sizes available please inquireTSG Twisted Gastrulation ProteinSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TSG 120-09 E.coli 22.2 kDa 10µg 50µg 1mgAdditional sizes available please inquireTTSLP Thymic stromal lymphopoietin proteinSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TSLP 300-62 E.coli 15.1kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TSLP 500-P258 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human TSLP 500-P258bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human TSLP CATALOG # 900-K334ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK Combination134

PEPROTECH ®www.peprotech.comTWEAK TNF-related weak inducer of apoptosisSynonyms: TNFSF12, DR3LG, Apo3 LigandRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TWEAK 310-06 E.coli 17.0 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human TWEAK 500-P137G Goat E, WB, N 50µg 100µg 1mgBiot. anti-human TWEAK 500-P137Gbt Goat E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human TWEAK CATALOG # 900-K149ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationTTWEAK Receptor TNF-related weak inducer of apoptosis receptorSynonyms: TNFRSF12A, FGF-inducible 14Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman TWEAK Receptor 310-21 E.coli 5.6 kDa 5µg 25µg 1mgAdditional sizes available please inquire135

www.peprotech.com2011-2012 VaspinSynonyms: Visceral adipose tissue-derived serpinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Vaspin 130-11 E.coli 45.2 kDa 5µg 25µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Vaspin 500-P256 Rabbit E, WB, NA 50µg 100µg 1mgBiot. anti-human Vaspin 500-P256bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedkDa148Representative Western Transfer (blot)analysis of human Vaspin using anti-humanVaspin at 0.20 µg/ml.6042V30221764VCAM-1Synonyms: CD106, INCAM-100, MGC108734, MGC99561, VCAM, VCAM1, VCAM1B, VECAM1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman VCAM-1 150-04 HEK 293 cells 74.1 kDa 10µg 50µg 1mgAdditional sizes available please inquire136

PEPROTECH ®www.peprotech.comVEGF Vascular endothelial growth factorSynonyms: VEGF-A, VPF, VAS, folliculostellate cell-derived growth factor, glioma-derived endothelialcell mitogenRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman VEGF 121100-20A E.coli 28.4 kDa 2µg 10µg 1mgHuman VEGF 165100-20 E.coli 38.2 kDa 2µg 10µg 1mgMurine VEGF 165450-32 E.coli 39.0 kDa 2µg 10µg 1mgRat VEGF 165400-31 E.coli 38.5 kDa 2µg 10µg 1mgAnimal-Free Recombinant ProteinsAdditional sizes available please inquirePRODUCT CATALOG # SOURCE MW Size A Size BHuman VEGF AF-100-20 E.coli 38.2 kDa N/A 10µg 1mgAdditional sizes available please inquirePolyclonal Antibodies - Antigen Affinity PurifiedPRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human VEGF 500-P10 Rabbit I, E, WB, N 50µg 100µg 1mgBiot. anti-human VEGF 500-P10bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-human VEGF 500-P10G Goat I, E, WB, N 50µg 100µg 1mgBiot. anti-human VEGF 500-P10Gbt Goat E, WB, NA 25µg 50µg 1mgAnti-murine VEGF 500-P131 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-murine VEGF 500-P131bt Rabbit E, WB, NA 25µg 50µg 1mgAnti-rat VEGF 500-P275 Rabbit E, WB, N 50µg 100µg 1mgBiot. anti-rat VEGF 500-P275bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedVMonoclonal AntibodiesPRODUCT CATALOG # SOURCE APPLICATIONS SizeAnti-human VEGF 500-M88 Mouse E, WB, N 500µgELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 1000 ELISA plate wells.Human VEGF CATALOG # 900-K10Murine VEGF CATALOG # 900-K99Rat VEGF CATALOG # 900-K436Mini ELISA Development KitEach kit contains: capture antibody, detection antibody, calibrated standard, and Avidin-HRP Conjugate, sufficient to assay the target cytokine in at least 200 ELISA plate wells.Human VEGF CATALOG # 900-M10Rat VEGF CATALOG # 900-M436ELISA Buffer Kit.ELISA Buffer Kit CATALOG # 900-K00ELISA Buffer Kit and EDK CombinationSee next page for IHC images of anti-human VEGF137

www.peprotech.com2011-2012 VEGF Continued…Anti-Murine VEGF (Catalog #500-P131)Mouse kidney (FFPE) stained with RabbitAnti-Murine VEGF at 2.5 μg/mL.VHuman breast invasive ductalcarcinoma (FFPE) stained with rabbitanti-human VEGF at 4.0 µg/ml andgoat anti-human VEGF at 10 µg/ml.Tissue samples were provided by the CooperativeHuman Tissue Network, which is funded by the NCI.Other investigators may have received specimensfrom the same subjects.Photographs by PeproTech.Rabbit anti-human VEGFGoat anti-human VEGFVEGF-B Vascular endothelial growth factor-BSynonyms: VEGF-related factor, VRFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman VEGF-B 100-20B E.coli 38.0 kDa 5µg 20µg 1mgAdditional sizes available please inquireVEGF-C Vascular endothelial growth factor-CSynonyms: Vascular endothelial growth factor-related protein, VRP, flt4 ligand, Flt4-LRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman VEGF-C 100-20C HEK 293 cells 20.0-22.0 kDa 5µg 20µg 1mgAdditional sizes available please inquire138

PEPROTECH ®www.peprotech.comVEGF-D Vascular endothelial growth factor-DSynonyms: c-fos-induced growth factor, FIGFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman VEGF-D 100-20D HEK 293 cells 20.0-26.0 kDa 2µg 10µg 1mgAdditional sizes available please inquireVisfatinSynonyms: PBEFRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Visfatin 130-09 E.coli 52.2 kDa 5µg 25µg 1mgAdditional sizes available please inquireVitronectinV-WSynonyms: VTN, Serum-spreading factor, V75Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Vitronectin 140-09 HEK 293 cells 52.2 kDa 50µg 250µg 1mgAdditional sizes available please inquireWISP-1 Wnt-1 inducible signaling pathway protein-1Synonyms: CCN4, Wnt-1-induced secreted proteinRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman WISP-1 120-18 E.coli 38.1 kDa 5µg 20µg 1mgAdditional sizes available please inquireWISP-3 Wnt-1 inducible signaling pathway protein-3Synonyms: CCN6Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman WISP-3 120-20 E.coli 36.8 kDa 5µg 20µg 1mgAdditional sizes available please inquire139

www.peprotech.com2011-2012 Wnt-1Synonyms: INT-1Recombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Wnt-1 120-17 E.coli 38.1 kDa 2µg 10µg 1mgPolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Wnt-1 500-P250 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Wnt-1 500-P250bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not testedWHuman breast invasive ductal carcinoma (FFPE) stained with rabbit anti-humanWnt-1 at 62.5 ng/mL. Staining of ductal carcinoma cells.Tissue samples were provided by the Cooperative Human Tissue Network, which is funded by the NationalCancer Institute. Other investigators may have received specimens from the same subjects.Photograph provided by Patsy Ruegg for PeproTechWnt-3aSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Wnt-3a 120-27C HEK 293 cells 38.1 kDa 2µg 10µg 1mgMurine Wnt-3a 315-20 cell culture 38.8-41.0 kDa 2µg 10µg N/APolyclonal Antibodies - Antigen Affinity PurifiedAdditional sizes available please inquirePRODUCT CATALOG # SOURCE APPLICATIONS Size A Size BAnti-human Wnt-3a 500-P251 Rabbit I, E, WB, NA 50µg 100µg 1mgBiot. anti-human Wnt-3a 500-P251bt Rabbit E, WB, NA 25µg 50µg 1mgBiot. = BiotinylatedKey: I = IHC, E = ELISA, WB = Western blot, N = Neutralization, NA = Neutralization not tested140

PEPROTECH ®www.peprotech.comWnt-7aSynonyms: noneRecombinant ProteinsPRODUCT CATALOG # SOURCE MW Size A Size BHuman Wnt-7a 120-31 HeLa cells 35.5 kDa 3µg 15µg N/AAdditional sizes available please inquireWPRODUCT CATALOG # SizeControl Goat Immunoglobulin 500-G00 1mgControl Mouse Immunoglobulin 500-M00 250µgControl Rabbit Immunoglobulin 500-P00 500µg141

www.peprotech.com2011-2012 INFORMATION & TECHNICAL SUPPORTKEYTm = memory T cellsB = B-cellsactT = activated T cellBs = BasophilT = resting T cellEo = EosinophilNK = Natural Killer cellsMo = monocytePMN = neutrophilsmDC = mature dendritic cellsiDC = immature DC142

www.peprotech.com Fibroblast Growth FactorsMW-Secretedform (murine)EstimatedpITarget Cells(Partial List)ReceptorsFunctions(Partial list)FGF1 (Acidic FGF) 15.8 7.99 mesenchymal, all FGF Angiogenic in vivo,Heparin-binding growth factor-1 (HBGF-1) (15.7kDa) (7.88) neuroectodermal receptors Mitogenic in vitro,Beta-endothelial cell growth factor endothelial cells wound healingECGF-beta (endothelial cell growth factor-beta)PEPROTECH ®development anddevelopment ofstomach cancerthat express FGFdevelopment,receptor 2bangiogenesis andwound healingthat expressdevelopmentFGF receptorsthat express FGFdevelopmentreceptors143FGF2 (Basic FGF) 17.2 10.03 mesenchymal, 1b,1c, Vasculogenesis, woundHeparin-binding growth factor-2 (HBGF-2) (17.1kDa) (9.59) neuroectodermal 2c, 3c,4 healing, angiogensis,Prostatropin endothelial cells hematopoiesis,neuron survivalFGF3 24.9 10.98 epithelial cells 2b Mesoderm induction,int-2 (25.2kDa) (10.84) that express FGF angiogenesis, inner earreceptor 2bdevelopmentFGF4 19.7 10.22 cells that express 1c, Angiogenesis,Heparin secretory transforming protein (HST-1) (18.9kDa) (10.24) FGF receptors 2c, 3c,4 vertabrate limbTransforming protein KS3Heparin-binding growth factor-4 (HBGF-4)FGF5 27.5 11.1 cells that express 1c,2c Hair growth andHeparin-binding growth factor-5 (HBGF-5) (27.1kDa) (10.50) FGF receptors developmentSmag-82FGF6 18.7 10.09 cells that express 1c,2c,4 Skeletal muscleHeparin-binding growth factor-6 (HBGF-6) (18.9kDa) (9.80) FGF receptors developmentHST-2FGF7/KGF (Kerotinocyte Growth Factor) 18.9 9.55 keratinocytes and 2b Keratinocyte growthHeparin-binding growth factor-7 (HBGF-7) (18.8kDa) (9.22) epithelial cells factor, kidney and lungFGF8 22.4 10.95 mammary 2c,3c,4 Limb, centralAndrogen-induced growth factor (AIGF) (28.0kDa) (10.46) carcinoma cells (possibly 1c) nervous system,Heparin-binding growth factor-8 (HBGF-8) and other cells cardiac outflow tractFGF9 23.4 7.44 glial cells, 1c,2c, Glia-activating factor,Glia activating factor (GAF) (23.3kDa) (7.44) astrocytes cells 3b,3c,4 motoneuron survival,Heparin-binding growth factor-9 (HBGF-9) and other cells lung and testesFGF10 19.3 10.49 epithelial cells 2b Wound healing,FGFA (19.5kDa) (9.76) that express FGF multi-organKeratinocyte growth factor 2 receptor 2b development includinglimb and lungINFORMATION & TECHNICAL SUPPORTFGF11 25.0 9.92 none Appears to be involvedFGFB (25.1kDa) (10.06) in nervous systemFibroblast Growth factor homologousdevelopmentfactor-3 (FHF-3)and functionFGF12 27.4kDa 9.98 none Appears to be involvedFGFCin nervous systemFibroblast Growth factor homologousdevelopmentfactor-1 (FHF-1)and function⾴頁

www.peprotech.com2011-2012 Fibroblast Growth FactorsMW-Secretedform (murine)EstimatedpITarget Cells(Partial List)ReceptorsFunctions(Partial list)FGF13 27.5 9.92 none Appears to be involvedFGFD (27.6 kDa) (9.92) in nervous systemFibroblast Growth factor homologousdevelopmentfactor-2 (FHF-2)and functionINFORMATION & TECHNICAL SUPPORTFGF14 27.7 10.11 none Regulates centralFGFE (27.7 kDa) (10.11) nervous systemFibroblast Growth factor homologousdevelopmentfactor-4 (FHF-4)and functionFGF15 (22.5 kDa) (5.76) cells that express unknown at Regulator of cellFGFF, identified in mouse not human FGF Receptor 4 time of division and patterningprinting in specific regions ofembroyonic brain,spinal cord andsensory organsFGF16 23.7 kDa 9.52 cells that express 2c, 3c Central Nervous SystemFGFG FGF receptors developmentFGF17 22.7 11.22 cells that express 1c, 2c, Signals induction andFGFH (22.5kDa) (10.71) FGF receptors 3c, 4 patterning of embryonicbrainFGF18 21.2 10.67 cells that express 1c, 2c, An essential regulatorzFGF5 (20.9kDa) (10.09) FGF receptors 3c, 4 of long bone andFGFIcalvarial developmentFGF19 21.8 kDa 6.32 cells that express 4 Expressed during brainFGFJ, identified in human not mouse FGF Receptor 4 development andduring embryogenesisFGF20 23.2 kDa 9.22 epithelial and 1c, 2c, 3c Expressed during limbFGFK mesenchymal cells and brain developmentFGF21 19.4 5.29 unknown at unknown at Expressed in liverFGFL (19.9 kDa) (4.59) time of printing time of printingFGF22 17.1 11.71 hair follicle- unknown at May be involvedFGFM (16.5 kDa) (11.58) keratinocytes time of printing in cutaneousdevelopment & repair,and hair developmentFGF23 25.3 8.95 renal proximal 3c Expressed in brain andFGFN (25.3 kDa) (9.64) epithelial cells thymus, regulatesphosphate homeostasis,mutant in hypophosphatemicrickets.144

www.peprotech.com PEPROTECH ®Functional NamesTNF-alpha, Cachectin, DIF, TNFSF2TNF-beta, LT alpha, TNFSF1LT beta, TNFC, p33OX40 Ligand (OX40L), gp34, TXGP1CD40 Ligand (CD40L), IMD3, TRAP, gp39, CD154, HIGM1, hyper-IgM syndromeFas Ligand (FasL), Apo I Ligand (ApoI L), APTL, APT1LG1, CD95LCD70, CD27 Ligand, CD27LG (CD27L, CD27LG)CD30 Ligand (CD30L, CD30LG), CD1534-1BB Ligand (4-1BBL), CD Antigen 137 Ligand (CD137L)TRAIL, Apo-2 Ligand (Apo2L), TL2RANK Ligand (RANKL), TRANCE, OPGL, ODFTWEAK, DR3LG, APO3-Ligand (APO3L)APRIL, TALL2BAFF, BLyS, THANK, TALL1, DTLLIGHT, LTγ, HVEM-Ligand (HVEM-L)TL1A, TL1, VEGIAITR Ligand (AITRL), TL6, GITRL Ligand (GITRL)BAFF, BLyS, THANK, TALL1, DTL, TNFSF13BFunctional NamesTNF Receptor Type I (TNFR1), TNFAR, TNF-R55, TNFR60, p55-R, p55TNFR, p55, CD120aTNF Receptor Type II (TNFR2), CD120b, p75, TNF-R, TNFR80, TNF-R75, TNFBR, p75TNFRTNFR2-RP, CD18, TNFR-RP, TNFCR, TNF-Receptor Type III (TNFR3)OX40, ACT35, TXGP1LCD40 (Receptor), p50, Bp50Fas, CD95, Apo-1, APT1DcR3, M68, TR6CD27, Tp55, S152CD30 , Ki-1, D1S166E4-1BB (Receptor), CD137, ILADR4, Apo2, TRAIL Receptor 1 (TRAILR1)DR5, TRAIL Receptor 2 (TRAIL-R2), KILLER, TRICK2A, TRICKBDcR1, TRAILR3, LIT, TRIDDcR2, TRUNDD, TRAILR4RANK (Receptor), ODFR, TRANCE ROsteoprotegerin (OPG), PRG, OCIF, TR1TNFRSF12 (bovine)TWEAK Receptor (TWEAKR), FN14DR3LTACIBAFFRHVEM, ATAR, TR2, LIGHTR, HVEANGFR, p75NTKBCMA, BCMAITR, GITR, GITR-DTROY, TRADE, TAJRELTDR6SOBa, Tnfrh2, 2810028K06Rik, DcTRAIL R2mSOB, Tnfrh1, DcTRAIL R1DR3, Apo-3, TRAMP, LARD, TR3, WSL-1, TNFRSF12TNFRH3145Nomenclature NameTNFSF1ATNFSF1BTNFSF3TNFSF4TNFSF5TNFSF6TNFSF7TNFSF8TNFSF9TNFSF10TNFSF11TNFSF12TNFSF13TNFSF13BTNFSF14TNFSF15TNFSF18TNFSF20 Nomenclature NameTNFRSF1ATNFRSF1BTNFRSF3/LTBR: (lymphotoxin beta receptor)TNFRSF4TNFRSF5TNFRSF6TNFRSF6BTNFRSF7TNFRSF8TNFRSF9TNFRSF10ATNFRSF10BTNFRSF10C: (decoy without an intracellular domain)TNFRSF10DTNFRSF11ATNFRSF11B(TNFRSF12)TNFRSF12ATNFRSF12LTNFRSF13BTNFRSF13CTNFRSF14TNFRSF16TNFRSF17TNFRSF18TNFRSF19TNFRSF19LTNFRSF21TNFRSF22TNFRSF23TNFRSF25TNFRSF26INFORMATION & TECHNICAL SUPPORT

www.peprotech.com2011-2012 Natural Antagonists/Name Synonyms Main Function Binding ProteinsINFORMATION & TECHNICAL SUPPORTTGF-β 1Differentiation inhibiting Regulates cell proliferation, growth, differentiation Follistatin, Follistatinfactor, cartilage-inducing and motility. Involved in adipogenesis, -like related genefactor chondrogenesis, embryogenesis, tissue remodeling, (FLRG), Decorin,wound healing and tumor formation.alpha-2macroglobulinTGF-β 2Glioblastoma-derived Regulates cell proliferation, growth, differentiation Decorin, alpha-2T-cell suppressor factor, and motility. Involved in adipogenesis, macroglobulinBSC-1, Cetermin,chondrogenesis, embryogenesis, tissue remodeling,Polyerginwound healing and tumor formation.TGF-β 3None Regulates cell proliferation, growth, differentiationand motility. Involved in adipogenesis,chondrogenesis, embryogenesis, tissue remodeling,wound healing and tumor formation.TGF-β 4Endometrial bleeding asso- Essential for left-right (L-R) asymmetryciated factor beta-4, (EBAF) determination of organ systems. Possible role inLefty preproprotein, LEFTA endometrial bleeding.Inhibin A Inhibin alpha & beta A Inhibits secretion of follitropin by the pituitarygland, regulates embryogenesis, osteogenesis,hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic,pituitary and gonadal glands.Inhibin B Inhibin alpha & beta B Inhibits secretion of follitropin by the pituitarygland, regulates embryogenesis, osteogenesis,hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic,pituitary and gonadal glands.Activin A Activin beta-A, Inhibin Regulates embryogenesis, osteogenesis, Follistatin,beta-1, FRP, (Follicle- hematopoiesis, reproductive physiology and Follistatin-likestimulating hormone- hormone secretion from the hypothalamic, pituitary related gene (FLRG),releasing protein),FSH- and gonadal glands. GASP-1, Cerberus,releasing protein, FSH-DAN, alpha2releasing factor, EDFmacroglobulin.(Erythroid differentiation factor)Activin AB Activin beta A & beta B Regulates embryogenesis, osteogenesis,hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.Activin B Activin beta-B, Inhibin Regulates embryogenesis, osteogenesis,beta-2hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.Activin C Activin beta-C, Inhibin Regulates embryogenesis, osteogenesis,beta-C, blastocyst B1 hematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.Activin E Activin beta-E, Regulates embryogenesis, osteogenesis,inhibin-beta Ehematopoiesis, reproductive physiology andhormone secretion from the hypothalamic, pituitaryand gonadal glands.BMP-2 BMP-2A Induces cartilage and bone formation, plays a Noggin, Chordin,role in cardiac morphogenesis.Follistatin,Follistatin-like relatedgene (FLRG), DAN,Cerberus, GremlinBMP-3 Osteogenin Induces cartilage and bone formation.146

www.peprotech.com Natural Antagonists/Name Synonyms Main Function Binding ProteinsBMP2B2, Bmp2-rs1) mesoderm induction, tooth development, limb Chordin-like/formation and fracture repair.Neuralin/DAN,Cerberus, GremlinVg-1-related proteincalcium regulation and bone homeostasis. May act Follistatin-relatedas an osteoinductive factor responsible for epithelial gene (FLRG),osteogenesis.DAN, Cerberus,Sclerostin/SOSTOP-2 (Osteogenic protein-2) calcium regulation and bone homeostasis. May actas an osteoinductive factor responsible for epithelialosteogenesis.and neural tissues and in establishing the skeletal Follistatin-likemuscle. Acts globally to specific positional identity related gene (FLRG),along the anterior/posterior axis.GASP-1PEPROTECH ®147BMP-3B GDF-10 Biological function unknown, but may play a rolein differentiation of osteoblasts, augmenting BMP-2activity.BMP-4 BMP2B (BMP2B1, Induces cartilage and bone formation, involved in Noggin, Chordin,BMP-5 None Induces cartilage and bone formation. Noggin, Chordinlike/Neuralin/Ventroptin,Sclerostin/SOSTBMP-6 Vgr-1, Induces cartilage and bone formation. Noggin, Chordinlike/Neuralin/Ventroptin Follistatin,Follistatin-likerelated gene (FLRG),Sclerostin/SOSTBMP-7 OP-1 (Osteogenic protein-1) Induces cartilage and bone formation, involved in Noggin, Chordin,BMP-8 BMP-8a, Induces cartilage and bone formation, involved inBMP-8b None Stimulates cartilage and bone formation, implicatedin calcium regulation and bone homeostasis.BMP-9 GDF-2 May be involved in bone formation, regulates bloodglucose homeostasis, potential autocrine/paracrinemediator in the hepatic reticuloendothelial system,involved in chondrogenesis.BMP-10 None Plays a crucial role in trabeculation of theembryonic heart.BMP-11 GDF-11 Involved in the patterning of both mesodermal Follistatin,BMP-12 GDF-7, CDMP-3 Induces the formation of tendon and ligamenttissues.BMP-13 GDF-6, CDMP-2 Plays a role in cartilage homeostasis, involved in the Nogginembroyonic skeletal development, and formation ofa tendon-like tissue.BMP-14 GDF-5, CDMP-1 Essential for limb cartilage and limb-joint formation Noggin, DANin developing mice. Involved in the embryonicskeletal development.BMP-15 GDF-9B An oocyte-specific factor that regulates granulosacell proliferation and differentiation, and is essentialfor normal follicular growth.GDF-1 Embryonic growth/ May be involved in mediating cell differentiationdifferentiation factor events during embryonic development.INFORMATION & TECHNICAL SUPPORT⾴頁

www.peprotech.com2011-2012 Natural Antagonists/Name Synonyms Main Function Binding ProteinsINFORMATION & TECHNICAL SUPPORTGDF-2 BMP-9 Implicated in bone formation.GDF-3 Vgr-2 Embryonal carcinoma stem cell-associated markerin vitro and in vivo.GDF-5 CDMP-1, BMP-14 Essential for limb cartilage and limb-joint formation Noggin, DANin developing mice, involved in the embryonicskeletal development.GDF-6 BMP-13, CDMP-2, Formation of a tendon-like tissue. Plays a role in Noggindynamo (zebrafish) cartilage homeostasis, and embryonic skeletaldevelopment.GDF-7BMP-12, CDMP-3, prostate Induces the formation of tendon and ligamentdifferentiation factor, tissues.MIC-1, PLABGDF-8 Myostatin (MSTN) Regulates skeletal muscle mass. Follistatin,Follistatin-likerelated gene(FLRG), GASP-1GDF-9 None Essential for normal follicular growth.GDF-10 BMP-3B, Biological function unknown, but may play a roleBIP (Bone-Inducing Protein) in differentiation of osteoblasts, augmentingBMP-2 activity.GDF-11 BMP-11 Involved in the patterning of both mesodermal and Follistatin,neural tissues and in establishing the skeletal Follistatin-likemuscle. Acts globally to specific positional identity related gene (FLRG),along the anterior/posterior axis.GASP-1GDF-15 PLAB, placental bone Possible mediator of placental control of embryonicprotein, prostatedevelopment, may act as an autocrine regulatorydifferentiation factor, molecule.NRG1, MIC-1(Macrophage Inhibiting Cytokine-1)GDNF ATF (Astrocyte derived Promotes dopamine uptake and survival andneurotrophic factor) morphological differentiation of midbrain neurons.Artemin ARTN Supports the survival of all peripheral ganglia suchas sympathetic, neural crest and placodally-derivedsensory neurons, and dopaminergic midbrainneurons.Neurturin NTN, NRTN Promotes the development and survival ofsympathetic and sensory neurons.Persephin PSP, PSPN Promotes the survival of ventral midbraindopaminergic neurons and motor neurons, andpromotes ureteric bud branching.LEFTY-1 LEFTYB, Protein Lefty B Essential for left-right asymmetry of organ systems.LEFTY-2 LEFTYA, TGF-β 4, Essential for left-right asymmetry of organ systems.Protein Lefty AAMH MIS, Muellerian Causes regression of the Muellerian duct,inhibits(anti-Muellerian inhibiting substance the growth of tumors derived from tissues ofhormone)Muellerian duct origin.Dorsalin dorsalin-1, DSL-1 Regulates cell differentiation within neural tube.(chick)NODAL None Essential for mesoderm formation and Cerberussubsequent organization of axial structures.148

www.peprotech.com Natural TGF-β Antagonists Structural Features Contained in the Known TGF-β BindingAntagonist Polypeptide (M.W.)PartnersNoggin unique Noggin cysteine knot (26 kDa) BMP-2,-4,-5,-6,-7,-13/GDF-6,-14/GDF-5Chordin 4 CR/VWCC (Chordin) domains, BMP-2,-4,-73 SOG repeats (102 kDa)PEPROTECH ®3 cysteine-rich Follistain (FS) and 3 kazal activin, BMP-2,-4,-6,-7, myostatin/GDF-8,GDF-11, TGFβ-1149Chordin-like/Neuralin/Ventroptin 3 Chordin domains (51 kDa) BMP-4,-5,-6Follistatindomains (38 kDa)Follistatin-like related gene 2 FS and 2 kazal domains (28 kDa) activin, myostatin/GDF-8, GDF-11, TGFβ-1(FLRG)GASP-1 1 Wap, 1 FS, 1 kazal, 1 IG-like, myostatin/GDF-8, GDF-112 kunitz, 1 netrin domains (63 kDa)Follistatin-related protein 1 FS, 1 CR/VWRC, activin, BMP-2,-6,-7(FSRP)2 EF-hand domains (35 kDa)DAN unique DAN cysteine knot (19 kDa) BMP-2,-4,-7, -14/GDF-5Cerberus DAN-like cysteine knot (30 kDa) BMP-2,-4,-7, activin, nodalGremlin DAN-like cysteine knot (21 kDa) BMP-2,-4,-7Sclerostin/SOST unique Sclerostin cysteine knot (24 kDa) BMP-5, -6Decorin multiple leucine-rich repeats (40 kDa) TGFβ-1, -2alpha-2 macroglobulin multiple proteinase inhibitor domains TGFβ-1, -2 , activin, inhibin(163 kDa)INFORMATION & TECHNICAL SUPPORT

www.peprotech.com2011-2012 ⾎血⽩白⼀一LP Particle Size Density (g/ml)* TG/CE Ratio* L/P Ratio* Associated ApoproteinsCM 1000nm

www.peprotech.com⼀一AA (aa) Amino AcidAAPABTSAECAPARbMEBSABtCHOConADaDABDIAntigen-Affinity Purifiedazino-diethylbenzothiazoline-sulfonate3-amino-9-ethylcarbazoleAlkaline PhosphataseAntigen Retrievalbeta-MercatoethanolBovine Serum AlbuminBiotinylatedChinese Hamster Ovary (cells)Concanavalin ADaltons“3,3' Diaminobenzidine”DeionizedDMEM Dulbecco’s Modified Eagle MediumDMSO Dimethyl SulfoxideDTTED50EDKECMEIAEIERELISAEUESFACSFBSFCSFFPEFLISAGtHClDithiothreitol50% Effective DoseELISA Development KitExtra Cellular MatrixEnzyme ImmunoassayEnzyme-Induced Epitope RetrievalEnzyme-Linked Immunosorbent AssayEndotoxin UnitEmbryonic Stem CellsFluorescence-Activated Cell SorterFetal Bovine SerumFetal Calf SerumFormalin-Fixed Paraffin-EmbeddedFluorescence-linked immunosorbent assayGoatHydrochloric acidHEK293 Human Endothelial Kidney CellsHIERHoAcHPLCHRPHSAHSCHeat-Induced Epitope RetrievalAcetic AcidHigh-Performance Liquid ChromatographyHorseradish PeroxidaseHuman Serum AlbuminHematopoietic Stem CellsPEPROTECH ®HUVEC Human Umbilical Venous Endothelial CellsICC ImmunocytochemistryIgG Immunoglobulin GIgE Immunoglobulin EIHC ImmunohistochemistryIU International UnitkDa kilodaltonsLAL Limulus Amoebocyte Lysate assayLPS LipopolysaccharideMAb Monoclonal AntibodyMSDS Material Safety Data SheetMW Molecular WeightMSC Mesenchymal Stem CellsNaP (NaPO4) Sodium PhosphateNFDM Nonfat Dry MilkNK Natural Killer CellsNM Nitrocellulose MembraneNSC Neural Stem CellsO.D. Optical DensityPAb Polyclonal AntibodyPAGE Polyacrylamide gel electrophoresisPCR Polymerase Chain ReactionPBL Peripheral Blood LymphocytesPBS Phosphate Buffered SalinePBST PBS with 0.1% TWEEN-20PBMC Peripheral Blood Mononuclear CellsPHA PhytohemagglutininpI Isoelectric PointPIER Protease-Induced Epitope RetrievalRb RabbitRIA RadioimmunoassayRT Room TemperatureSDS Sodium Dodecyl SulfateTBS Tris Buffered SalineTFA Trifluoroacetic AcidTMB “3,3',5,5'-tetramethylbenzidine”WB Western BlotWFI Water Force InjectionWHO World Health Organization151INFORMATION & TECHNICAL SUPPORT

www.peprotech.com2011-2012 INFORMATION & TECHNICAL SUPPORT⾯面⾏行行⽤用⽐比⾏行行⽤用⽣生 ⽩白⽤用⽐比⾏行行⽤用⽣生⽤用⽩白⾏行行⼀一 ⽩白⽩白⾼高⽰示⼤大⻑⾧長⽩白⽤用⽩白 ⽩白⽣生⽩白⽩白⽩白 ⽤用⽬目⾒見見⽩白⼼心⼼心⽩白⼿手 ⽐比⽐比⼤大 ⼒力力⽅方⽤用⽤用 ⽐比1 x 10 6 ⽐比ED 50(ng/ml)=⽰示⼤大⽰示⽰示⽐比⽐比⽐比⾼高⽐比⽰示⽰示⽰示⾮非⾼高152

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www.peprotech.com ⽤用⽤用⼿手 ⾮非⽤用 NH 2 +HNOCSNHC NH (CH 2)56 - Aminocaporic AcidOO 2 3 2 ON - biotinyl - 6 - aminocaproic acidN - succinimidyl esterOOO NCONHSOOOAvid-EnzINFORMATION & TECHNICAL SUPPORTOOOPEPROTECH ®159

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www.peprotech.com ⽤用⼊入⽤用⻑⾧長⽉月⻑⾧長⼊入⼿手⽤用⼿手⾦金金⽇日⽉月⽇日⽣生⽤用⽤用⾎血⾎血⽤用⽌止⽌止⽤用⽌止⾼高⼀一 ⾼高 ⽌止⽤用⽌止⽂文⽌止⽰示⽌止⽤用⽤用⽤用PEPROTECH ®⼀一⽤用⾏行行⼀一⽤用⼀一⽤用⼊入⼀一⽤用⼀一⽌止⽌止⽤用 ⾏行行⽩白⽴立立⾃自⽤用⽤用⽤用⽤用 ⽤用⽤用 161INFORMATION & TECHNICAL SUPPORT

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www.peprotech.com⽣生⼤大⽩白⾏行行⽤用⼩小⽩白⼦子⽩白⽤用⾎血⼦子⼦子⼊入⽤用⽤用⼿手⾯面⽤用⽬目⼦子⼦子⽩白⽩白⼦子⽤用⾊色⻄西⼿手⼗十⽴立立⽤用⽩白⼤大⽤用⽬目 ⽬目⽤用⽩白⽩白⼆二⽤用⽤用⾼高⽰示⾄至PEPROTECH ®177⼗十⼤大⽐比⾏行行⾎血⽰示⽩白⾛走⾏行行⽐比⾏行行⽩白⽩白⽐比⾏行行⽅方⽋欠⽩白⾎血⾼高⽩白⽐比⽩白⾎血 ⾮非⽩白⼆二⼀一⼤大⽐比⾼高⼀一⾼高INFORMATION & TECHNICAL SUPPORT

www.peprotech.com2011-2012 ⽤用⽤用⽩白⼊入(1) Fung, Eric ed. Protein arrays: methods and protocols. Fremont,CA: Humana Press Inc.; 2004.(2) Ye, S. and Day, I. eds. et al. Microarrays and Microplates: applicationsin biomedical sciences. Oxford, UK: BIOS ScientificPublishers Ltd.; 2003.(3) Zhou, Heping, et al. Genome Biology, Vol. 5, issue 4, R28; 2004.INFORMATION & TECHNICAL SUPPORT ⽩白⽩白⽩白⾛走 ⾊色 ⽩白⽩白⽐比⽩白αγγ178

www.peprotech.com ⽩白PEPROTECH ®⼀一179⾏行行αγ⽰示αγINFORMATION & TECHNICAL SUPPORT

www.peprotech.com2011-2012 INDEX14 kDa lectin ..................................................... see Galectin-126 kDa protein .............................................................see IL-628 kD (GBP28) ...............................................see Adiponectin4-1BB Ligand .................................................................... p.164-1BB Receptor ................................................................ p.166Ckine .................................................................see Exodus-2ABCD-1 ....................................................................see MDCABCD-2 ...................................................................see TARCAcrp30 .............................................................see AdiponectinACT-2 .................................................................... see MIP-1βActivin A ........................................................................... p.12Activin B ........................................................................... p.12activins-binding protein .....................................see FollistatinAdipogenesis inhibitory factor (AGIF)..................... see IL-11Adipolean (human). ............................................. see gAcrp30Adipolean variant (human) ......................see gAcrp30 VariantAdiponectin ....................................................................... p.12AdipoQ ............................................................see AdiponectinAdipose tissue-specific secretory factor (ADSF).. see ResistinAIGF ....................................................................... see FGF-8AITRL ............................................................................... p.12Aldesleukin .................................................................see IL-2ALP ......................................................................see CTACKAlpha defensin-1 ........................................................see NP-1AMAC-1 ..................................................................see MIP-4Aminopeptidase ............................................................... p.13Amphiregulin .................................................................... p.13Angiopoietin-1 (ANG-1) .................................................. p.13Apm-1 variant ..........................................see gAcrp30 VariantApm-1 .............................................................see AdiponectinApo I ............................................................. see Fas ReceptorApo I Ligand .................................................... see Fas LigandApo2 Ligand ...........................................................see TRAILApo3 Ligand ........................................................see TWEAKApoA-1 ............................................................................. p.13ApoE2 ............................................................................... p.14ApoE3 ............................................................................... p.14ApoE4 ............................................................................... p.14Apo-SAA........................................................................... p.14AR ............................................................. see AmphiregulinAPRIL ............................................................................... p.15APTL ................................................................ see Fas LigandARIA .............................................................see Heregulinβ-1ART .......................................................................see ArteminArtemin ............................................................................. p.15ATAC ...........................................................see LymphotactinATF-1 ...................................................................... see GDNFB71 .................................................................................... p.16B cell stimulatory factor-2 receptor ....................IL-6 receptorBAFF................................................................................. p.17BAFF Receptor ................................................................. p.17BCA-1 ............................................................................... p.18BCDF ..........................................................................see IL-6BCDFII .......................................................................see IL-5BCGF ..........................................................................see IL-4BCM ........................................................................see BCMABCMA ............................................................................... p.18BD-1 .................................................................................. p.19BD-2 .................................................................................. p.19BD-3 .................................................................................. p.19BD-4 .................................................................................. p.19BDNF ................................................................................ p.20Betacellulin ....................................................................... p.20Beta-glactoside-binding lectin L-14-I ............... see Galectin-1BLC .........................................................................see BCA-1BLR1 Ligand ..........................................................see BCA-1BLys ......................................................................... see BAFFBMP-2 ...............................................................................p.21BMP-3 ...............................................................................p.21BMP-4 ...............................................................................p.21BMP-6 ...............................................................................p.22BMP-7 ...............................................................................p.22BMP-11 .................................................................see GDF-11BMP-13 ............................................................................. p.22BMP-14 ...................................................................see GDF-5BMP-15 ................................................................ see GDF-9BBolekine ..................................................................see BRAKB-R1 .........................................................................see I-TACBRAK ............................................................................... p.23Breast cancer cell differentiation factor p45 .............. see Heregulinβ-1BSC-1 .................................................................... see TGF-β2BSF-1 (B-cell stimulating factor) ...............................see IL-4BSF-2 ..........................................................................see IL-6BTC .................................................................see BetacellulinB-TCGF ....................................................................see IL-10C10 .................................................................................... p.23Cachectin .................................................................see TNF-αCarboxypeptidase B .......................................................... p.23Cardiotrophin-1 ................................................................. p.24Cardiotrophin-like cytokine ........................ see NNT-1/BSF-3Cartilage-inducing factor ...................................... see TGF-β1Catabolin ...................................................................see IL-1βCCF18 ....................................................................see MIP-1γCCK-1 ....................................................................... see MECCCL1 ......................................................................... see I-309CCL2 ...................................................................... see MCP-1180

www.peprotech.comCCL3 ...................................................................... seeMIP-1αCCL3L1 ..................................................................see LD78βCCL4 ..................................................................... see MIP-1βCCL4L1 ..................................................................see LAG-1CCL5 ...................................................................see RANTESCCL6 ........................................................................... see C10CCL7 ...................................................................... see MCP-3CCL8 ...................................................................... see MCP-2CCL9/10 .................................................................see MIP-1γCCL11 ....................................................................see EotaxinCCL12 .................................................................... see MCP-5CCL13 .................................................................... see MCP-4CCL14 .....................................................................see HCC-1CCL15 ......................................................................see MIP-5CCL16 .........................................................................see LECCCL17 ......................................................................see TARCCCL18 ......................................................................see MIP-4CCL19 ................................................................... see MIP-3βCCL20 .................................................................... seeMIP-3αCCL21 .................................................................see Exodus-2CCL22 .......................................................................see MDCCCL23 ......................................................................see MIP-3CCL24 ................................................................ see Eotaxin-2CCL25 ......................................................................see TECKCCL26 ................................................................ see Eotaxin-3CCL27 ...................................................................see CTACKCCL28 ....................................................................... see MECCCN2 .......................................................................see CTGFCCN4 .................................................................... see WISP-1CCN5 .....................................................................see CTGFLCCN6 .................................................................... see WISP-3sCD14 ...............................................................................p.24sCD22 ............................................................................... p.24sCD23 ............................................................................... p.25sCD27L ............................................................................. p.25sCD30L ............................................................................. p.25sCD100 ............................................................................. p.26CD120a ............................................see TNF Receptor Type ICD120b ...........................................see TNF Receptor Type IICD124 ..........................................................see IL-4 ReceptorCD126 ..........................................................see IL-6 ReceptorCD137 antigen .........................................see 4-1BB ReceptorCD137L ....................................................... see 4-1BB LigandCD154 .......................................................... see CD40 LigandCD25 antigen ...............................................see IL-2 ReceptorCD252 antigen ..................................................... see sOX40LCD40 Ligand ..................................................................... p.26CD95 ............................................................. see Fas ReceptorPEPROTECH ®CD95L .............................................................. see Fas LigandCDMP-1 ..................................................................see GDF-5CDMP-2 ............................................................... see BMP-13CDNF ................................................................................ p.27Cetermin ................................................................ see TGF-β2Chemerin ........................................................................... p.27CINC ....................................................................... see GROαCkB-6 ................................................................. see Eotaxin-2c-Kit Ligand ................................................................see SCFCkβ-8 .......................................................................see MIP-3c-MPL Ligand .............................................................see TPOCNTF ................................................................................ p.27Colon Cancer Cell Growth Inhibitor ................... see IGF-BP4Control Goat Immunoglobulin ........................................ p.141Control Mouse Immunoglobulin..................................... p.141Control Rabbit Immunoglobulin ..................................... p.141CPB-35 .............................................................. see Galectin-3Crg-2 ......................................................................... see IP-10Cryptdin .....................................................................see NP-1CSF-1 ..................................................................... see M-CSFCSF-2 .................................................................. see GM-CSFCSF-3 ......................................................................see G-CSFCSIF ..........................................................................see IL-10CT-1 ......................................................... see Cardiotrophin-1CT-58 .....................................................................see CTGFLCTACK ............................................................................ p.28CTAP-III .................................................................see NAP-2CTGF ................................................................................ p.28CTGFL/WISP-2 ................................................................ p.28CTL maturation factor (TCMF)................................see IL-12CTLA-4 ............................................................................. p.29CTLA-8 .................................................................. see IL-17ACX3CL1 ........................................................... see FractalkineCXCL1 .................................................................... see GROαCXCL2 .................................................................... see GROβCXCL3 .....................................................................see GROγCXCL4 ....................................................................... see PF-4CXCL5 ..................................................................see ENA-78CXCL6 ....................................................................see GCP-2CXCL7 ....................................................................see NAP-2CXCL8 ........................................................................see IL-8CXCL9 ....................................................................... see MIGCXCL10 .................................................................... see IP-10CXCL11 ...................................................................see I-TACCXCL12 .............................................................see SDF-1α/βCXCL13 ..................................................................see BCA-1CXCL14 ..................................................................see BRAKCXCL16 ............................................................................ p.29181INDEX

www.peprotech.com2011-2012 INDEXCYR61 .............................................................................. p.29Cysteine-rich secreted protein FIZZ1 .................. see RELMαCysteine-rich secreted protein FIZZ2 ...................see RELMβCytotoxic lymphocyte maturation factor (CLMF)....see IL-12Cytotoxin.................................................................see TNF-αDC-CK1 ...................................................................see MIP-4DDAH ............................................................................... p.30DIF ..........................................................................see TNF-αDifferentiation inhibiting factor ............................ see TGF-β1Diphtheria toxin receptor .....................................see HB-EGFDKK-1 ...............................................................................p.30DLL-1 ...............................................................................p.30DLL-4 ...............................................................................p.30DR3LG .................................................................see TWEAKDR4 ....................................................... see TRAIL receptor 1DR5 ....................................................... see TRAIL receptor 2DT-R .....................................................................see HB-EGFECGF-beta .......................................................see FGF-acidicEDF .............................................................................see IL-5EGF ................................................................................... p.31EGF receptor ..................................................................... p.32EG-VEGF ......................................................................... p.32ELC ....................................................................... see MIP-3βEMAP-II ........................................................................... p.32ENA-78 ............................................................................. p.33Endostatin ......................................................................... p.33Enterokinase ...................................................................... p.34Eotaxin .............................................................................. p.34Eotaxin-2 ........................................................................... p.35Eotaxin-3 ........................................................................... p.35EP .......................................................................... see IL-1α/βEPC-1 ....................................................................... see PEDFEPG .........................................................................see EpigenEpigen ............................................................................... p.36Epiregulin .......................................................................... p.36Epithelial mitogen ...................................................see EpigenEREG ................................................................ see EpiregulinE-Selectin .......................................................................... p.36Eskine ....................................................................see CTACKETGF.......................................................................see TGF-αExodus-1 ............................................................... see MIP-3αExodus-2 ........................................................................... p.37Exodus-3 ............................................................... see MIP-3βsFas Antigen .................................................. see Fas ReceptorFas Ligand ......................................................................... p.38Fas Receptor ...................................................................... p.38FGF-1 ...............................................................see FGF-acidicFGF-2 ................................................................ see FGF-basicFGF-4 ...........................................................................p.39-41FGF-5 ...........................................................................p.39-41FGF-6 ...........................................................................p.39-41FGF-7/KGF ..................................................................p.39-41FGF-8 ...........................................................................p.39-41FGF-9 ...........................................................................p.39-41FGF-10 .........................................................................p.39-41FGF-16 .........................................................................p.39-41FGF-17 .........................................................................p.39-41FGF-18 .........................................................................p.39-41FGF-19 .........................................................................p.39-41FGF-20 .........................................................................p.39-41FGF-21 .........................................................................p.39-41FGF-22 .........................................................................p.39-41FGFA ..................................................................... see FGF-10FGF-acidic ...................................................................p.39-41FGF-basic .....................................................................p.39-41FGFG .................................................................... see FGF-16FGFH .................................................................... see FGF-17FGFI ...................................................................... see FGF-18FGF-inducible 14 ................................. see TWEAK ReceptorFGFJ ...................................................................... see FGF-19FGFK .................................................................... see FGF-20FIZZ3 .................................................................... see Resistinflt3L .................................................................. see flt3-Ligandflt3-Ligand ......................................................................... p.42Folliculostellate cell-derived growth factor .............see VEGFFollistatin .......................................................................... p.42Fractalkine ......................................................................... p.43Frizzled related protein-1 ....................................... see sFRP-1FRP-1 ..................................................................... see sFRP-1FS .......................................................................see FollistatingAcrp30 ............................................................................. p.43gAcrp30 variant ................................................................ p.43GAF......................................................................... see FGF-9Galactose-specific lectin-3 ................................ see Galectin-3Galaptin ............................................................. see Galectin-1Galectin-1 .......................................................................... p.44Galectin-3 .......................................................................... p.44GCP-2 .............................................................................. .p.45G-CSF ............................................................................... p.46GDF-2 ............................................................................... p.46GDF-3 .............................................................................. .p.47GDF-5 ............................................................................... p.47GDF-6 .................................................................. see BMP-13GDF-8 ................................................................see MyostatinGDF-11 ............................................................................. p.47GDF-15/MIC-1 ................................................................. p.47182

www.peprotech.comGDGF ..................................................................... see PDGFsGDNF ............................................................................... .p.48gelatin-binding protein ....................................see AdiponectinGITRL .....................................................................see AITRLGlioblastoma-derived T cell suppressor factor ..... see TGF-β2Glioma-derived endothelial cell mitogen .................see VEGFGLP-1 ................................................................................ p.48Glial Maturation Factor-beta ..................................see GMF-βGlu-C................................................................................. p.48Glucagon-like peptide ............................................. see GLP-1Glycoprotein Gp34 ............................................... see sOX40LGM-CSF ............................................................................ p.49GM-CSFβ ...............................................................see G-CSFGMF-β .............................................................................. p.50gp39.............................................................. see CD40 LigandGranzyme B ...................................................................... p.50GROα ................................................................................ p.51GROβ ............................................................................... .p.51GROγ .............................................................................. ..p.51GRO1 ...................................................................... see GROαGRO2 ...................................................................... see GROβGRO3 .......................................................................see GROγGrowth-hormone-dependent binding proteins .... see IGF-BP3H3 relaxin ........................................................... see Relaxin-3HARP ............................................................. see PleiotrophinHB-EGF ............................................................................ p.52HBGF-1............................................................ see FGF acidicHBGF-2..............................................................see FGF basicHBGF-4................................................................... see FGF-4HBGF-5................................................................... see FGF-5HBGF-6................................................................... see FGF-6HBGF-7.......................................................... see FGF-7/KGFHBGF-8................................................................... see FGF-8HBGF-9................................................................... see FGF-9HC14 ...................................................................... see MCP-2HCC-1 ............................................................................... p.52HCC-2 ......................................................................see MIP-5HCC-3 .....................................................................see HCC-1HCC-4 .........................................................................see LECHCGF (Hematopoietic cell growth factor) .................see IL-3HCS24 ......................................................................see CTGFHematopoietin-1 ...................................................... see IL-1αHeparin-binding growth factor-8 (HBGF-8).. see PleiotrophinHeregulinβ-1 ..................................................................... p.53HGF................................................................................... p.53HGNF .........................................................................see NT-3HHG-1 ......................................................see Sonic HedgehogHNP-1 ........................................................................see NP-1PEPROTECH ®HP1.A .......................................................................see TTF-1HPGF ..........................................................................see IL-6HPTA .......................................................................... see HGFHRG ..............................................................see Heregulinβ-1HSF .............................................................................see IL-6HST-1 ...................................................................... see FGF-4HST-2 ...................................................................... see FGF-6HVEM-L ................................................................ see LIGHTHVEM-Fc ......................................................................... p.54I-309 .................................................................................. p.54IBP-1 ................................................................... see IGF-BP1IBP-2 ................................................................... see IGF-BP2ICAM-1 .............................................................................p.55IFN-β .................................................................................p.55IFN-β2 .........................................................................see IL-6IFN-γ ............................................................................p.56-57IFN-λ1 ............................................................................... p.57IFN-λ2 ............................................................................... p.57IFN-ω ................................................................................ p.57IgE-binding protein ........................................... see Galectin-3IGF-I ................................................................................. p.58IGF-IA .......................................................................see IGF-IIGF-II ................................................................................ p.58IGF-BP1 ............................................................................ p.59IGF-BP2 ............................................................................ p.59IGF-BP3 ............................................................................ p.59IGF-BP4 ............................................................................ p.59IGF-BP5 ............................................................................ p.59IGF-BP6 ............................................................................ p.59IGF-BP7 ............................................................................ p.59IGFBPrP1 ............................................................ see IGF-BP7IL-10-inducible chemokine .........................................see LECIL-1α ................................................................................. p.60IL-1β ................................................................................. p.61IL-1RA .............................................................................. p.62IL-2 ................................................................................... p.63IL-2 Receptor α ................................................................ p.64IL-3 ................................................................................... p.64IL-4 ................................................................................... p.65IL-4 Receptor α ................................................................ p.66IL-5 ................................................................................... p.66IL-6 ..............................................................................p.67-68IL-6 Receptor α ................................................................ p.68IL-7 ................................................................................... p.69IL-8 ..............................................................................p.69-70IL-9 ................................................................................... p.70IL-10 ................................................................................. p.71IL-11 .................................................................................. p.72183INDEX

www.peprotech.com2011-2012 INDEXIL-12 ................................................................................. p.73IL-13 ................................................................................. p.74IL-13 variant ..................................................................... p.74IL-15 ................................................................................. p.75IL-16 ................................................................................. p.75IL-17A/IL-17 .................................................................... p.76IL-17B ............................................................................... p.77IL-17D ............................................................................... p.77IL-17E ............................................................................... p.77IL-17F ............................................................................... p.78IL-18BP ............................................................................. p.78IL-19 ................................................................................. p.79IL-20 ................................................................................. p.79IL-21 ................................................................................. p.80IL-22 ................................................................................. p.81IL-23 ................................................................................. p.82IL-25 ..........................................................................see SF20IL-28A .................................................................... see IFN-λ2IL-29 ...................................................................... see IFN-λ1IL-31 ................................................................................. p.82IL-33 ................................................................................. p.83IL-34 ................................................................................. p.83IL-T ...........................................................................see IL-15IL-TIF .......................................................................see IL-22Immune Interferon ....................................................see IFN-γInsulin-like peptide-7 ......................................... see Relaxin-3INSL7 ................................................................. see Relaxin-3Int-1 ........................................................................ see WNT-1Int-2 ...........................................................................see FGF3IP-10 .................................................................................. p.84Iroplact ....................................................................... see PF-4I-TAC ................................................................................ p.85JE............................................................................ see MCP-1KC ........................................................................... see GROαKex-2 ................................................................................. p.85KGF......................................................................... see FGF-7KILLER ...............................................see TRAIL Receptor-2KLF4-TAT ......................................................................... p.86Klotho ...............................................................................p.86L-29 ................................................................... see Galectin-3LAF ....................................................................... see IL-1α/βLAG-1 ............................................................................... p.86LARC .................................................................... see MIP-3αLCC-1 .........................................................................see LECLD78α ................................................................... see MIP-1αLD78β ............................................................................... p.86LEC ................................................................................... p.87LEM ...................................................................... see IL-1α/βLeptin ...........................................................................p.87-88LIGHT ............................................................................... p.88Lin28-TAT ......................................................................... p.88LIX ........................................................................see ENA-78Lkn-1 ........................................................................see MIP-5LMC ............................................................................see LECLungkine ........................................................................... p.89Luterotropic hormone ..........................................see ProlactinLutetropin .............................................................see ProlactinLymphocyte chemoattractant factor (LCF)...............see IL-16Lymphopoietin-1 (LP-1) .............................................see IL-7Lymphotactin .................................................................... p.89Lymphotoxin-alpha (LT-α) ..................................... see TNF-βMAC2 ............................................................... see Galectin-3MAF ..........................................................................see IFN-γMammotropin ......................................................see ProlactinMARC .................................................................... see MCP-3Maspin............................................................................... p.89Mast cell growth-enhancing activity (murine)............see IL-9MCF ...................................................................... see IL-1α/βMCGF .........................................................................see IL-3MCP-1 ..........................................................................p.91-92MCP-2 ..........................................................................p.91-92MCP-3 .........................................................................p.91-92MCP-4 .........................................................................p.91-92MCP-5 ..........................................................................p.91-92M-CSF............................................................................... p.90MDC ................................................................................. p.93MDNCF ......................................................................see IL-8MEC .................................................................................. p.93Megakaryocyted colony-stimulating factor ................see TPOMelanoma differentiation associated-like protein.....see IL-19MGDF .........................................................................see TPOMGF ............................................................................see SCFMGI-1G ...................................................................see G-CSFMGI-1GM ........................................................... see GM-CSFMGI-2 .........................................................................see IL-6MGI-IM .................................................................. see M-CSFMGSAα .................................................................. see GROαMGSAβ ................................................................... see GROβMGSAγ ....................................................................see GROγMIA ................................................................................... p.94MIA-2 ............................................................................... p.94MIAL ...................................................................... see OTORMidkine ............................................................................. p.95MIG ................................................................................... p.95MIP-1α .........................................................................p.96-97MIP-1β .........................................................................p.96-97184

www.peprotech.comMIP-1γ .............................................................................. p.97MIP-2 .........................................................................see GROMIP-3 .............................................................................. ..p.98MIP-3α .............................................................................. p.98MIP-3β .............................................................................. p.99MIP-4 ................................................................................ p.99MIP-5 .............................................................................. p.100MMP-1 ............................................................................ p.100MMP-2 ............................................................................ p.100MMP-3 ............................................................................ p.100Monocyte Arg-Serpin ................................................see PAI-2MPIF-1 .....................................................................see MIP-3MPIF-2 ............................................................... see Eotaxin-2MRP-1 ......................................................................... see C10MRP-2 ....................................................................see MIP-1γMTN-1 ........................................................................see LECMulti-Colony stimulating factor ................................see IL-3Mycoplasma Arginine Deiminase .................................. p.100Myostatin ........................................................................ p.101Myostatin Propeptide ...................................................... p.101NAF.............................................................................see IL-8Nanog .............................................................................. p.101Nanog-TAT ...................................................................... p.101NAP-1 .........................................................................see IL-8NAP-2 ............................................................................. p.102NAP-3 ..................................................................... see GROαNC30 (Human) ..........................................................see IL-13NCC-1 .................................................................... see MCP-4NCC-2 .....................................................................see HCC-1NCC-4 .........................................................................see LECNecrosin ..................................................................see TNF-αNEGF-2 .................................................................see MidkineNeu differentiation factor ..............................see Heregulinβ-1Neuregulin1 ...................................................see Heregulinβ-1Neuritin ...........................................................................p.102Neuropoietin ................................................................... p.102Neuroserpin ..................................................................... p.103Neurotactin ....................................................... see FractalkineNeurotrophic factor ....................................................see NT-3Neurturin ......................................................................... p.103NGF-β ............................................................................. p.104NGF-2 ........................................................................see NT-3NKSF ........................................................................see IL-12NNT-1/BSF-3 .................................................................. p.105NOGGIN ......................................................................... p.105NOV ................................................................................ p.105NP-1 ................................................................................ p.106NP ..................................................................see NeuropoietinPEPROTECH ®NPO...............................................................see NeuropoietinNRG ..............................................................see Heregulinβ-1NRTN ..................................................................see NeurturinNT-3 ................................................................................ p.106NT-4 ................................................................................ p.106NT-4/NT-5 ..................................................................see NT-4NTN ....................................................................see NeurturinObesity protein (OB)................................................see LeptinOCIF ........................................................ see OsteoprotegerinOct4-TAT ....................................................................... p.107ODAR ..................................................... see RANK ReceptorODF...................................................................... see RANKLODFR ...................................................... see RANK ReceptorODGF ..................................................................... see PDGFsOncostatin A ............................................................... see PF-4Oncostatin M ................................................................... p.107OP-7 ....................................................................... see BMP-7OPG.......................................................... see OsteoprotegerinOPGL ................................................................... see RANKLOSF-1 ............................................................. see PleiotrophinOSM ............................................................. see Oncostatin MOsteopontin ..................................................................... p.107Osteoprotegerin ............................................................... p.108OTOR .............................................................................. p.108Otoraplin ................................................................. see OTORsOX40L ........................................................................... p.108OX40 Ligand (OX40L)........................................ see sOX40Lp16-INK4a ......................................................................p.109p16-INK4a-TAT ..............................................................p.109P40 cytokine ................................................................see IL-9P55 ..................................................see TNF Receptor Type IIP75 ..................................................see TNF Receptor Type IIP80 ..................................................see TNF Receptor Type IIP600 (Murine)...........................................................see IL-13PAF-AH ..........................................................................p.109PAI-1 ............................................................................... p.109PAI-2 ............................................................................... p.109PARC .......................................................................see MIP-4PBEF ......................................................................see VisfatinPBP ..........................................................................see NAP-2PBSF ..................................................................see SDF-1α/βP-cell stimulation factor ..............................................see IL-3PDGF-AA ....................................................................... p.110PDGF-AB ...................................................................... .p.110PDGF-BB ....................................................................... .p.110PDGF-CC ....................................................................... p.110PECAM-1 ........................................................................p.111PEDF ................................................................................p.111185INDEX

www.peprotech.com2011-2012 INDEXPersephin ..........................................................................p.111PF-4 ..................................................................................p.111PGF ...........................................................................see PlGFPK2 ............................................................. see Prokineticin-2Placenta Protein 12 (PP12) ................................. see IGF-BP1Placental TGF-β ....................................................see GDF-15Pleiotrophin ..................................................................... p.112PlGF-1 ............................................................................. p.112PlGF-2 ............................................................................. p.113PlGF-3 .............................................................................p.113Pluripoietin ..............................................................see G-CSFPluripoietin-α ...................................................... see GM-CSFPNR2 ........................................................................see TFF-1Polyergin ............................................................... see TGF-β2Pre-B cell factor ..........................................................see IL-7Pre-B cell colony-enhancing factor .......................see VisfatinPROK1 ..............................................................see EG-VEGFProkineticin-1 ....................................................see EG-VEGFProkineticin-2 .................................................................. p.113Prolactin ......................................................................... p.114Prostatropin ....................................................... see FGF-basicProstate differentiation factor....................see GDF-15/MIC-1Protease inhibitor 5 ................................................ see MaspinProtease inhibitor 12 ...................................... see NeuroserpinProtein Bv8 homolog ................................. see Prokineticin-2pS2 ...........................................................................see TFF-1PSP ..................................................................... see PersephinPSPN .................................................................. see PersephinPTHrP .............................................................................. p.114PTN .................................................................see pleiotrophinRANK receptor ............................................................... p.116RANKL ........................................................................... p.115RANTES ......................................................................... p.117Relaxin-2 ......................................................................... p.118Relaxin-3 ......................................................................... p.118RELMα ........................................................................... p.118RELMβ ........................................................................... p.119RELMγ ............................................................................ p.119Resistin ............................................................................ p.120Sarcoma growth factor ............................................see TGF-αScatter Factor ............................................................. see HGFSCF ................................................................................. p.121SCGFα ............................................................................ p.122SCGFβ ............................................................................ p.122SCM-1a ........................................................see LymphotactinSDF-1α ........................................................................... p.122SDF-1β ............................................................................ p.122Serpin B2 ..................................................................see PAI-2Serpin B5 ............................................................... see MaspinSerpin E1 ...................................................................see PAI-1Serpin F1 .................................................................. see PEDFSerpin I1 ......................................................... see NeuroserpinSF ............................................................................... see HGFSF20 ................................................................................ p.123sFRP-1.............................................................................. p.43SIS-delta ..............................................................see RANTESsHH ..........................................................see Sonic HedgehogSkinkine ................................................................see CTACKS-LAC lectin-1 .................................................. see Galectin-1SLC .....................................................................see Exodus-2Slit2-N ............................................................................. p.123Smag-82 .................................................................. see FGF-5Somatamedin A ....................................................... see IGF-IISomatamedin C .........................................................see IGF-ISonic Hedgehog ............................................................. p.123Sox2 ................................................................................ p.123Sox2-TAT ........................................................................ p.123SPARC/Osteonectin ........................................................ p.124Spasmmolysin ........................................................... see TFF2Spasmolytic Polypeptide (SP)................................... see TFF2SRPSOX ............................................................. see CXCL16STCP-1 ......................................................................see MDCSteel Factor .................................................................see SCFT cell growth factor p40 ..............................................see IL-9T cell interferon .........................................................see IFN-γTAC-antigen .................................................see IL-2 ReceptorTACI................................................................................ p.124TAFA ............................................................................... p.125TALL-1 .................................................................... see BAFFTARC .............................................................................. p.125T-BAM ......................................................... see CD40 LigandTCA-3 ....................................................................... see I-309TCGF ..........................................................................see IL-2TECK .............................................................................. p.125TFF1 ................................................................................ p.126TFF2 ................................................................................ p.126TFF3 ................................................................................ p.126TGF-type I ..............................................................see TGF-αTGF-α ............................................................................. p.126TGF-β1 ........................................................................... p.127TGF-β2 ........................................................................... p.127TGF-β3 ........................................................................... p.127TGIF ..........................................................................see IL-10THANK .................................................................... see BAFFThrombomodulin ........................................................... p.127TIGAR ........................................................................... p.127186

www.peprotech.comTIGAR-TAT ................................................................... p.127TIMP-1 ............................................................................ p.128TIMP-2 ............................................................................ p.128TL-1A .............................................................................. p.129TL2 ..........................................................................see TRAILTL6 ..........................................................................see AITRLTLR-3 ..............................................................................p.129TNF Receptor Type I ...................................................... p.131TNF Receptor Type II ..................................................... p.132TNFAR ............................................ see TNF Receptor Type ITNF-R55 ..........................................see TNF Receptor Type ITNFR60 ...........................................see TNF Receptor Type ITNFR75 ......................................... see TNF Receptor Type IITNFR80 ......................................... see TNF Receptor Type IITNFRSF1A ......................................see TNF Receptor Type ITNFRSF1B .....................................see TNF Receptor Type IITNFRSF6 .....................................................see FAS ReceptorTNFRSF9 .................................................see 4-1BB ReceptorTNFRSF10A ....................................... see TRAIL Receptor-1TNFRSF10B ....................................... see TRAIL Receptor-2TNFRSF11A ........................................... see RANK ReceptorTNFRSF11B ............................................ see OsteoprotegerinTNFRSF12A ........................................ see TWEAK ReceptorTNFRSF13B ............................................................. see TACITNFRSF13C .............................................see BAFF ReceptorTNFRSF17 ..............................................................see BCMATNFSF1................................................................... see TNF-βTNFSF2...................................................................see TNF-αTNFSF4................................................................ see sOX40LTNFSF5........................................................ see CD40 LigandTNFSF6............................................................ see Fas LigandTNFSF7.................................................................see sCD27LTNFSF8.................................................................see sCD30LTNFSF9....................................................... see 4-1BB LigandTNFSF10.................................................................see TRAILTNFSF11 .............................................................. see RANKLTNFSF12..............................................................see TWEAKTNFSF13.................................................................see APRILTNFSF13B ............................................................... see BAFFTNFSF14................................................................ see LIGHTTNFSF15................................................................. see TL-1ATNFSF18.................................................................see AITRLTNF-α ............................................................................. p.130TNF-β ............................................................................ .p.131TPO ................................................................................. p.132TR1 .......................................................... see OsteoprotegerinTRAIL ............................................................................. p.133TRAIL receptor-1 ............................................................ p.133PEPROTECH ®TRAIL receptor-2 ............................................................ p.134TRANCE.............................................................. see RANKLTRANCE receptor .................................. see RANK ReceptorTransforming protein KS3 ...................................... see FGF-4TRAP ........................................................... see CD40 LigandTRDL-1α ................................................................see APRILTRF .............................................................................see IL-5TRICK2A .............................................see TRAIL Receptor-2TRICKB .............................................. see TRAIL Receptor-2TSG ................................................................................. p.134TSLP ............................................................................... p.134TSF ............................................................................see IL-12TWEAK .......................................................................... p.135TWEAK Receptor ........................................................... p.135TXGP1 ................................................................. see sOX40LType II interferon ......................................................see IFN-γUNQ222/PRO248 ...................................................see GDF-3URG ............................................................................see EGFUrogastrone .................................................................see EGFUrokinase inhibitor ...................................................see PAI-2Vaspin .............................................................................. p.136VEGF-A ...................................................................p.137-138VEGF-B .......................................................................... p.138VEGF-C ..........................................................................p.138VEGF-D ..........................................................................p.139VEGI ....................................................................... see TL-1AVisfatin ............................................................................ p.139vMIP-2 .............................................................................. p.97VPF ..........................................................................see VEGFWISP-1 ............................................................................ p.139WISP-2 ...................................................................see CTGFLWISP-3 ............................................................................ p.139WNT-1 ............................................................................ p.140WNT-3A .......................................................................... p.140WNT-7A .......................................................................... p.141Wnt-1-induced secreted protein ............................ see WISP-1XCL-1 ........................................................see LymophotactinzFGF5 ................................................................... see FGF-18zTNF4 ...................................................................... see BAFF187INDEX

www.peprotech.com2011-2012 NotesINDEX188