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to download slide presentation - Educational Concepts Group

Agents Targeting the Vascular EndothelialGrowth Factor (VEGF) PathwayAnti-VEGFantibodies(bevacizumab)VEGFSolubleVEGFRs(VEGF-Trap)Small-molecule VEGFR inhibitors– Vatalanib (PTK 787)– Sunitinib (SU11248)– Sorafenib (Bay 43-9006)– ZD6474PPPPVEGFR-1PPPPVEGFR-2Endothelial cellAnti-VEGFRantibodies(IMC-1121b)Podar K, et al. Blood. 2005;105:1383-1395.

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