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Overall Survival by HistologyPemetrexed MaintenanceNon-squamous (n = 481)Squamous (n = 182)Survival Probability1.00.90.80.70.60.50.40.30.20.10.0HR = 0.70 (95% CI:0.56-0.88)P = 0.002Placebo10.3 mosPemetrexed 15.5 mo0 3 6 9 12 15 18 21 24 27 30 33 36 39 42 45 481.00.90.80.70.60.50.40.30.20.10.00Placebo10.8 mosHR = 1.07 (95% CI:0.49-0.73)P = 0.678Pemetrexed 9.9 mo3 6 9 12 15 18 21 24 27 3033 36 39 42 45 48Time (months)Time (months)Only 67% of patients in control arm received any second-line therapyand 19% received pemetrexedBelani CP, et al. J Clin Oncol. 2009;27(18s). Abstract CRA8000.

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