Ovarian Cancer: Genetic Counseling and Testing, Screening and ...

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BR 51OV 53 Brain 50OV 72BR 29BR 58High riskFollow-upBR 35BR 39BSOHigh riskFollow-up
Risk Reduction from removing ovaries (oophorectomy) inwomen with BRCA1/2 MutationsStudy<strong>Ovarian</strong> CaBreast CaKauff 2002 85% 68%Rebbeck 2002 96% 53%Rutter 2003 71% *Eisen 2005 * 56%Domchek 2006 89% 64%Finch 2006 80% *Rebbeck 2009 80% 51%
Page 1 and 2: Ovarian Cancer: Genetic Counseling
Page 3 and 4: Family History of Ovarian Cancer•
Page 5 and 6: BRCA1-Associated Associated Cancers
Page 7 and 8: BRCA2-Associated Associated Cancers
Page 9 and 10: Clinical Management ofBRCA Mutation
Page 11 and 12: BR 51Stom 53 Brain 50Liver 72BR 29B
Page 13: BR 51OV 53 Brain 50OV 72B1POSB1NEGB
Page 17 and 18: Other Benefits of Prophylactic Ooph
Page 19 and 20: BRCA1 familyProstate 60Colon 60B1B1
Page 21 and 22: Features That Indicate IncreasedLik
Page 23 and 24: Amsterdam Criteria• 3 or more rel
Page 25 and 26: Genetic Testing forCancer Susceptib
Page 27 and 28: Genetic Testing for Cancer Risk•
Page 29: Concerns regarding discrimination

Ovarian Cancer: Genetic Counseling and Testing, Screening and ...

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