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3 years ago

FLUNITRAZEPAM CASE STUDY

FLUNITRAZEPAM CASE STUDY

FLUNITRAZEPAM IN• T1/2 9-25 HrPLASMA• 2 mg dose avg. peak plasma concentrationof 8 ng/ml at 2 hrs, declining to 1.5 ng in 24• 7-aminoflunitrazepam peak of 2 ng/ml @ 9hrs• Desmethylflunitrazepam peak of 1 ng/ml at24 hrsDisposition of Toxic Drugs and Chemicals in Man, 6th Ed., RC Baselt, ed., Biomedical Publications,2002

FLUNITRAZEPAM IN URINE• Flunitrazepam @ 0.5-3 ng/ml within 6-24hrs.• 7-aminoflunitrazepam @ 50-500 ng/mlwithin 6-24 hrs• Both of above observed after a 2 mg doseDisposition of Toxic Drugs and Chemicals in Man, 6th Ed., RC Baselt, Ed., Biomedical Publications,2002

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