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LeagueNews - Cerebral Palsy League

LeagueNews - Cerebral Palsy League

LeagueNews - Cerebral Palsy

League NewsVOLUME 29 • NUMBER 3 • SUMMER 2005Cerebral Palsy League of Queensland Three times a yearNew causes of cerebralpalsy discoveredUNIVERSITY of Adelaide researchershave found a link between congenitalclotting disorders and cerebral palsy.Minute amounts of stored bloodsamples from healthy babies andthose with cerebral palsy were testedusing molecular biological testsadapted by Catherine Gibson.The reseach was part of her worktowards a PhD supervised byProfessor Alastair MacLennan andProfessor Gus Dekker at theUniversity of Adelaide and Dr PaulGoldwater at the Adelaide Women’sand Children’s Hospital.Thrombophilias (blood clottingdisorders) have been isolated asfactors associated with an increasedrisk of cerebral palsy in studiescarried out by the South AustralianCerebral Palsy Research Group(SACPRG) and published duringNovember in the American Journal ofObstetrics and Gynecology.Professor MacLennan said this wasthe first large case-control study ofcerebral palsy and hereditarythrombophilias.“We now have evidence that certainhereditary clotting disorders appearto increase the risk of cerebral palsy.“We were able to monitor this acrossgestational ages, and it was notedthat there was a higher prevalence ofcerebral palsy in babies with genemutations for any of three differentthrombophilias, who were bornprematurely.”“A five-fold increase in quadriplegiccerebral palsy was found at allgestational ages when two of thehereditary clotting disorders occurredtogether.”“We have also found that someintrauterine infections and hereditarysusceptibility to infection may becontributing factors to cerebral palsy.”This work, to be published soon, wasrecently presented at scientificmeetings both in Australia and in theUSA.“These factors may start anirreversible destruction process inparts of the fetal or neonatal brain thatcontrol posture and movement.The first signs of this problem maysometimes present as ‘fetal distress’at birth, however, this is oftenmisidentified as the ‘cause’ of cerebralpalsy, rather than as a symptom.“Efforts to speed up delivery in thesecircumstances have yet to be shownto reduce cerebral palsy rates,possibly because the destructiveprocess is already established.”Cerebral palsy is a common (one in400 births) disorder of movement withposture impairment, which haspreviously been assumed to resultfrom low oxygen levels encounteredduring the birth of the baby.Boardroom Blitz:‘Studio 54 Revisited’took Brisbane’s corporateelite to the infamous 1970sdiscotheque era.Left to right:Volunteers, the Xanadudes,Graeme Ballantyne, Lisa King,Chris O’Kane, Stefanie Van DerMeer.What’s Up?Discovery .................. page 1Heather Foord .......... page 16CRM ........................... page 7CP Week .................... page 8League Awards ......... page 5Gold Coast Getaway page 8Coming Up ................ page 1220-26 Februarywww.cplqld.org.au/mfr/colouryourdaySign up for 2006!Bring back the 80s!www.boardroomblitz.org.au(Continued on page 11)i dream, therefore I am1

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