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Accelerated Atherosclerosis Introduction

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<strong>Accelerated</strong> atherosclerosis inrheumatoid arthritis• Cardiovascular disease is a leading cause ofmortality in rheumatoid arthritis (RA).Endothelial dysfunction often precedesmanifest atherosclerosis.• Both traditional, Framingham risk factors andinflammation‐associated factors are involvedin RA‐associated atherosclerosis.Link Between Small‐vesselVasculitides and <strong>Atherosclerosis</strong>• Premature atherosclerosis has recentlyemerged as a late, but possibly severe,complication of systemic small‐vesselvasculitides, mainly represented by Wegener'sgranulomatosis, microscopic polyangiitis andChurg‐Strauss syndrome

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