“Curiculum Vitae” Athanasios J. Manolis, MD, FACC, FESC, FAHA

“Curiculum Vitae” 

Athanasios J. Manolis, MD, FACC, FESC, FAHA 

Head Cardiology Department, Asklepeion Hospital, Athens, Greece 

Adj. Professor of Medicine in Cardiology, Emory University, Atlanta, USA 

Adj. Assistant Professor of Hypertension, Boston University, Boston, USA 

41 Thassou str 

Athens, 16672 

Greece 

Tel: +30 210 8923630, +30 6944 946394 (mobile) 

Fax: + 30 210 8923209 

E-mail: ajmanol@otenet.gr. 

1

Current Positions: 

CV 

Athanasios J. Manolis, M.D. 

1. Head Cardiology Department, Asklepeion Hospital, Athens, Greece. 

2. Adj. Professor of Medicine in Cardiology, Emory University, Atlanta, USA 

3. Adj. Assistant Professor of Hypertension, Boston University, Boston, USA 

Marital status: married, two children 

Nationality: Greek 

Training/Previous positions 

1. 1973-1979: Athens University, Medical School 

2. 1980-1982: Greek Army 

3. 1983-1984: Training in Internal Medicine 

4. 1984-1987: Training in Cardiology 

5. 1987: Specialty in Cardiology 

6. 1987-2006: Senior Registrar in Cardiology, Tzanio General Hospital, Piraeus, 

Greece 

7. 1987-2006: Head Hypertension Clinic, Tzanio General Hospital, Piraeus, Greece 

8. 1987-1988: Training on Hypertension, Boston University, School of Medicine, 

Boston, USA 

9. 2006-present:: Head Cardiology, Asklepeion Hospital, Athens, Greece 

PhD 

“Pressor hormone profile during stress in hypertension: 

Does vasopressin interfere with left ventricular hypertrophy” 

2

Honorary Positions 

2001-2002 President of the Mediterranean Association of Cardiology and 

Cardiac Surgery 

1998-present Adj. Associate Professor on Hypertension and Atherosclerosis, 

Boston University, School of Medicine, Boston, USA 

2002-2006 Adj. Associate Professor of Medicine in Cardiology, Emory 

University, Atlanta, USA 

2007-present Adj. Professor of Medicine in Cardiology, Emory University, 

Atlanta, USA 

2002-2004 Council member of the Hellenic Society of Cardiology 

2003-present Member of the Board of the International Society of 

Cardiovascular Ultrasound 

2003-2011 Council member of the European Society of Hypertension 

2004-2006 Treasurer of the Hellenic Society of Cardiology 

2003 Honorary member of Cyprus Hypertension Society 

2008-2010 Vice President of the Working Group ‘Hypertension and Heart’ of 

the European Society of Cardiology 

2007 President of the 14 th World Congress of Echocardiography and 

Cardiovascular Ultrasound 

2007 President of the 1 st International Congress on Hypertension and 

Cardiovascular Prevention 

2007-2009 President of the Hellenic Society of Hypertension and 

Cardiovascular Prevention 

2010-2012 President of the Working Group ‘Hypertension and Heart’ of the 

European Society of Hypertension 

2014 President of the Joint meeting of the ESH/ISH (Athens, Greece) 

Government Honorary Positions 

2007-2009 Vice Pesident of National Institute of Health 

2007-2009 Member of the Council for the selection of Directors of Cardiology 

Departments in Greece 

2007-2009 Member of the Council for the selection of new registrars of 

Cardiology in Athens 

2007-present President of the suprime council of FDA Greece 

2006-2009t Councillor of the Minister of Health 

3

International 

Editorial Board/Reviewer 

Clinical Cardiology 

Journal Hypertension 

Blood Pressure 

Nephrology and Hypertension Digest 

Current Cardiology Reviews 

Recent Patent Reviews on Cardiovascular Drug Discovery 

British Heart Journal 

Journal American College of Cardiology 

Egyptian Heart Journal 

European Journal of Clinical Investigation 

National 

Blood Pressure 

Heart beats 

Hellenic Journal of Hypertension 

National Meeting 

Organizing Committee 

I have been involved since 1996 in the Organizing committee of most of the National 

meetings on Cardiology and Hypertension in Greece 

International 

I have been involved since 2002 in the organizing committee of more than 40 

international meetings and in all the meetings of the European Society of Hypertension 

4

President of International Meetings 

2002 14 th Annual meeting of the Mediterranean Association 

of Cardiology and Cardiac Surgery 

October 2002, Rhodes, Greece (1.200 participants) 

2004 14 th European Meeting on Hypertension, Paris, France 

Post Congress Satellite Symposium 

‘Metabolic Syndrome, 

June 2004, Santorini, Greece (250 participants) 

2005 15 th European Meeting on Hypertension, Milan, Italy 


‘Metabolic Syndrome. A clinical challenge’ 

June 2005, Myconos, Greece (400 participants) 

Advances and Developments in Bioscience and Biotechnology 

Athens, Greece (450 participants) 

2006 16 th European Meeting on Hypertension, Madrid, Spain 


‘Treating Hypertensive patients with multiple risk factors’ 

June 2007, Myconos, Greece (670 participants) 

2007 XIth World Congress of Echocardiography and Vascular Ultrasound, Rhodes, 

Greece and 

1 st International Congress on Hypertension and Cardiovascular Prevention 

June 2007, Rhodes, Greece (1.750 participants) 

2014 Joint Meeting of the International Society of Hypertension and European Society 

of Hypertension 

Athens, Greece (8.000-10.000 participants) 

Member/Fellow of Medical Societies 

International 

Fellow of the European Society of Cardiology 

Fellow of the American College of Cardiology 

Member of the American Association of Advanced Science 

Member of the European Heart Network 

Member of the Mediterranean Association of Cardiology and Cardiac Surgery 

5

Fellow of the Hypertensive Council of the American Heart Association. 

Μember of the American Society of Hypertension 

Member of the Interamerican Society of Hypertension 

Member of the Working Group Hypertension and Heart of the European Society of 

Cardiology 

Member of European Society of Hypertension 

Μember of International Society of Hypertension 

National 

1. Member of the Hellenic Society of Cardiology 

2. Member of the Hellenic Society of Hypertension 

Multicenter International Trials 

Principal Investigator 

1.1987-1988: ACE-I plus Diuretic in primary hypertension 

2.1988-1989: A study to compare the antihypertensive efficacy of Tenormin 

50-100mg once daily with a combination of Tenormin 50mg and 

Enalapril 10mg dosed once daily 

3.1989-1990: TEMS: Assessment of trimetazidine activity in stable angina pectoris 

vs propanolol. 

4.1990-1991: A long term, randomized phase III survival study of oral milrinone, 

captopril and digoxin in congestive heart failure patients 

5.1990-1992: 3 rd Generation b-blockers in primary hypertension 

6.1991-1992: Regression of left ventricular hypertrophy with isradipine in 

previously untreated hypertensive patients. 

7.1991-1993: AAI and ACE-I in primary hypertension 

8.1991-1994: EMIAT: European Myocardial Infarct Amiodarone Trial 

9.1992-1993: The influence of hypolidemic treatment in the progression of by-pass 

grafts and the percentage of restenosis post PTCA 

6

10.1992-1997: HOT STUDY: Hypertension Optimal Therapy 

11.1993-1999: ELSA: European Lacidipine Study on Atherosclerosis 

12.1995-1996: Double-blind, prospectively randomized, parallel group study of the 

antihypertensive effects of Moxonidine versus Enalapril in patients with 

essential hypertension 

13.1996-1997: A multicenter double-blind prospectively randomized comparison 

between three combinations of Moxonidine with hydrochlorothiazide, 

amlodipine or enalapril in hypertensive patients unresponsive to 

Moxonidine monotherapy. 

14.1997-1998: A randomized, triple-blind, parallel study of the efficacy and safety of 

Losartan versus Atenolol in patients with isolated systolic hypertension 

15.1997- SCOR NIH, Genetic Epidemiology and Molecular Genetics of Cardiovascular 

Diseases. 

16.1998-1999: A multicenter, double blind, randomized parallel group study to 

compare the antihypertensive efficacy of Losartan versus Candesartan 

Cilexetil in patients with mild to moderate hypertension 

17.1998-2000: Clinical study of the Efficacy and Tolerability of Nebivonol versus 

Amlodipine in the treatment of essential hypertension in elderly patients 

18.1999-2000: A prospective Randomized, Open-Label, Blinded Endpoint (PROBE), 

Parallel Group Study Comparing a One Step Response Based Titration 

Regimen of 12 Weeks Duration of Telmisartan with Enalapril in Patients 

wit Essential Hypertension 

19.1999-2000: A prospective, multinational multicenter, Double-Blind, Randomized, 

active controlled trial in patients with essential hypertension to compare the effect of 

Valsartan 80 and 160mg,with or without the addition of 

hydrochlorothiazide, once daily to that of amlodipine 5 and 10mg once 

daily, with or without the addition of hydrochlorothiazide, on 

cardiovascular morbidity and mortality (VALUE STUDY) 

20.1999-2000: Angiotensin II Receptor Antagonist Telmisartan in Isolated Systolic 

Hypertension (ARAMIS STUDY) 

21.1999-2000: Omapatrilat versus Enalapril Randomized trial of utility in reducing 

events (OVERTURE STUDY) 

7

22. 1999-2000: A double blind, randomized, active-controlled, parallel group trial 

comparing the combinations of valsartan 160 mg plus 

hydrochlorothiazide 12,5 mg and valsartan 160 mg in patients with mild 

to moderate essential hypertension not adequately controlled with 

valsartan 160 mg. 

23. 2000-2001: A multi centre, randomized, parallel group double blind, placebo- 

controlled one year study to evaluate the efficacy and tolerability of 

bupropion hydrochloride (SR) versus placebo as an aid to smoking 

cessation in a population of smokers with established, stable 

cardiovascular diseases 

24. 2000-2001: A prospective, Randomized, Open-Label, Blinded-Endpoint, Parallel 

Group Study Comparing Telmisartan plus Hydrochlorothiazide in 

Subjects with Essential Hypertension. 

25. 2000-2001: A prospective, Randomized, Open-Label, Parallel Group Study to 

Investigate the Effects of 12 months Treatment with Telmisartan plus 

Hydrochlorothiazide on Left Ventricular Mass Index in Subjects with 

Left Ventricular Hypertrophy and Essential hypertension. 

26. 2000-2001: A four week, multi-centre, double-blind, placebo-controlled, 

prospective comparison between combinations or oral eprosartan with 

atenolol, lisinopril or amlodipine in hypertensive patients not optimally 

responding to eprosartan monotherapy 

27. 2002: A multicenter, Double Blind, Randomised, Parrale Group Study to Evaluate 

the Effects of two different doses of losartan on morbidity and mortality 

in patients with symptomatic heart failure intolerant of ACE inhibitor 

Treatment (HEAAL STUDY) 

28. 2004: An International, Multicentre, Open Label Study To Assess The Effectiveness 

Of Amlodopine – Atorvastatin Combination In Subjects With 

Hypertension and Dyslipidaemia. (The JEWEL II Study) 

29. 2005: Double blind, randomized, parallel group, multicentre study to evaluate the 

efficacy and tolerability of CHF 1521 (fixed combination of manidipine 

and delapril) vs Losartan 50 mg and hydrochlorothiazide 12.5 mg in type 

2 diabetic hypertensive patients. 

(MORE study) 

2007 -2008 

30. Ολοκληρωµένη Μελέτη Αξιολόγησης Καρδιαγγειακών Τελικών Σηµείων 

και Εκβάσεων µε Rimonabant –Comprehensive Rimonabant Evaluation 

8

70.000 Euro 

Study of Cardiovascular ENDpoints and Outcomes). Tυχαιοποιηµένη, 

πολυεθνική, πολυκεντρική, διπλή τυφλή, ελεγχόµενη µε εικονικό 

φάρµακο, δύο σκελών, παραλλήλων οµάδων µελέτη του Rimonabant σε 

δόση των 20 mg άπαξ ηµερησίως για τη µείωση του κινδύνου εµφάνισης 

µειζόνων καρδιαγγειακών συµβαµάτων σε ασθενείς µε κοιλιακή 

παχυσαρκία και αθροιστικούς παράγοντες κινδύνου (Crescendo study) 

31. Πανευρωπαική τυχαιοποιηµένη, παραλλήλων οµάδων, 2 σκελών, 

ελεγχόµενη µε εικονικό φάρµακο, διπλή τυφλή, πολυκεντρική µελέτη 

του Rimonabant των 20mg άπαξ ηµερησίως στη θεραπεία ασθενών µε 

κοιλιακή παχυσαρκία µε δυσλιπιδαιµία µε ή χωρίς άλλες συν- 

νοσηρότητες (Eternal study) 

20.000 Euro 

32. Randomised evaluation of long term anticoagulant therapy (RE-LY) 

comparing the efficacy and safety of two blinded doses of dabigatran 

etexidate with open label warfarin for the prevention of stroke and 

systemic embolism in patients with non-valvular atrial fibrillation: 

prospective, multi –centre, parallel –group, non –inferiority trial (Rely 

study) 

100.000 Euro 

33. Kατάθεση της ετήσιας αναφοράς προόδου της κλινικής µελέτης µε τίτλο: 

«Η δράση της επλενερόνης έναντι του εικονικού φαρµάκου στην 

καρδιαγγειακή θνησιµότητα και την νοσηλεία σε νοσοκοµείο εξαιτίας 

καρδιακής ανεπάρκειας σε ασθενείς µε χρόνια συστολική καρδιακή 

ανεπάρκεια κατηγορίας ΝΥΗΑ ΙΙ (Emphasis- ΗF study) 

40.000 Euro 

34. «Οι επιδράσεις της ιβαµπραδίνης στα καρδιαγγειακά συµβάντα σε 

ασθενείς µε µέτρια έως βαρείας µορφής χρόνια καρδιακή ανεπάρκεια και 

συστολική δυσλειτουργία της αριστερής κοιλίας. Τριετής 

τυχαιοποιηµένη διπλή-τυφλή ελεγχόµενη µε εικονικό φάρµακο διεθνής 

πολυκεντρική µελέτη»(Shift study) 

100.000 Euro 

35. «Μια πολυκεντρική, τυχαιοποιηµένη, διπλά τυφλή, ελεγχόµενη µε 

εικονικό φάρµακο µελέτη, της επίδρασης του Ενέσιµου Εναιωρήµατος 

KW-3902 σε ενδείξεις και συµπτώµατα καρδιακής ανεπάρκειας, τη 

διούρηση, την νεφρική λειτουργία και τα κλινικά αποτελέσµατα σε 

ασθενείς νοσηλευόµενους µε επιδεινούµενη νεφρική λειτουργία και 

καρδιακή ανεπάρκεια που απαιτεί ενδοφλέβια θεραπεία»(Reach up 

study) 

50.000 Euro 

9

36. «Τυχαιοποιηµένη, διπλή-τυφλή µελέτη φάσης III ελέγχου της 

αποτελεσµατικότητας και της ασφάλειας της ενδοφλέβιας σιδηρικής 

καρβοξυµαλτόζης (Ferinject) σε σύγκριση µε εικονικό φάρµακο, σε 

ασθενείς µε χρόνια καρδιακή ανεπάρκεια και σιδηροπενεία»(Vifor 

study) 

24.000 Euro 

37. «Προοπτική, τυχαιοποιηµένη, διπλή τυφλή, διπλή εικονική, παράλληλων 

οµάδων, πολυκεντρική, υποκινούµενη από σύµβαµα µελέτη µη 

κατωτερότητας για τη σύγκριση της αποτελεσµατικότητας και της 

ασφάλειας του χορηγούµενου άπαξ ηµερησίως από του στόµατος 

Rivaroxaban (BAY 59-7939) µε ρυθµισµένης δόσης από του στόµατος 

βαρφαρίνη για την πρόληψη εγκεφαλικού επεισοδίου και συστηµατικής 

εµβολής εκτός του κεντρικού νευρικού συστήµατος σε συµµετέχοντες µε 

µη βαλβιδική κολπική µαρµαρυγή»(Rocket study) 

150.000 Euro 

38. Μία διπλή, πολυκεντρική, τυχαιοποιηµένη πολυπαραγοντική ελεγχόµενη 

µε εικονικό φάρµακο µελέτη παράλληλων οµάδων διάρκειας 8 

εβδοµάδων για την αξιολόγηση της αποτελεσµατικότητας και ασφάλειας 

του aliskiren χορηγούµενο ως µονοθεραπεία καθώς και σε συνδυασµό µε 

αµλοδιπίνη σε ασθενείς µε ιδιοπαθή υπέρταση. 

60.000 Euro 

39. Efficacy and safety of zofenopril/HCTZ combination vs 

Irbesartan/HCTZ combination in essential hypertensive patients not 

controlled by previous monotheraphy. 

30.000 Euro 

40. Blood pressure control and antihypertensive treatment among physicians 

of the private sector. 

15.000 Euro 

41. Μία κλινική µελέτη έκβασης της νταραπλαντίµπης έναντι 

εικονικού φαρµάκου σε ασθενείς µε χρόνια στεφανιαία για τη σύγκριση της επίπτωσης 

των µείζονων καρδιαγγειακών συµβαµάτων (Stability Trial) 

125.000 Euro 

10

Publications in International Journals 

IMPACT FACTOR: 260 

CITATION INDEX: 1500 

1. Kouvaras G, Manolis AJ, Cokkinos DV: Calcification of the tricuspid annulus. 

Case report and Review of the Relevant Literature. Japanese Heart Journal 

1987;28:561-566 

2. Wierzba T, Manolis AJ, Gavras I, Burstzyn M, Gavras H: Enalapril in mild 

to moderate Hypertension. Current Therapeutic Research 1990;48:1101-1110. 

3. Manolis AJ, Kolovou G, Handanis S, Athanasopoulos G, Antonopoulos S, 

Cokkinos DV: Regression of left ventricular hypertrophy with isradipine in 

previously untreated hypertensive patients. American Journal Hypertension 1993;6:86S- 

88S 

4. Manolis AJ, Athanasopoulos G, Karatasakis G, Gavras I, Bresnahan M, 

Cokkinos DV, Gavras H: Pressor hormone profile during stress in hypertension: Does 

vasopressin interfere with left ventricular hypertrophy? Clin and Exper Hypertension 

1993;15(3):539-555. 

5. Kolovou G, Fostinis J, Athanasopoulos G, Manolis AJ, Cokkinos DV: 

Differential response of high-density lipoproteins to first step lipid lowering 

diet according to their initial level. Coronary Artery Disease 1994;5:359-364 . 

6. Gavras I, Manolis AJ, Gavras H: Effects of ACE inhibition on the heart 

Journal of Human Hypertension 1995;9:455-458. 

7. Manolis AJ, Gavras I, Pieprzak M, Gavras H: Isradipine versus Captopril 

in patients with essential hypertension. Clinical Therapeutics 1995;17:648-655. 

8. Manolis AJ, Olympios C, Sifaki M, Handanis S, Bresnaham M, Gavras I, 

Gavras H: Suppressing sympathetic activation in congestive heart failure: 

A new therapeutic strategy. Hypertension 1995;26:719-724. 

9. Manolis AJ, Gavras I, Gavras H: Clonidine and Heart Failure. 

Hypertension 1996, 27:1187-1188. 

10. Tsagadopoulos D, Antonakoudis H, Makris T, Votteas V, Vyssoulis G, 

Manolis AJ, Babalis D, Lefkos N, Achimastos A, Toutouzas P: Effect of 

antihypertensive treatment on lipids and fibrinogen: Greek multicenter study of 

Cilazapril. Cardiology, 1996, 87:524-528. 

11. Manolis AJ, Olympios C, Sifaki M, Handanis S, Cokkinos D, Bresnaham M, 

11

Gavras I, Gavras H: Combined Sympathetic Suppression and Angiotensin 

Converting Enzyme Inhibition in Congestive Heart Failure. Hypertension 29 (part 

2) 1997;29:525-530. 

12. Gavras I, Manolis AJ, Gavras H: Drug therapy for Hypertension. 

American Family Physician 1997;55:1823-1834. 

13. Manolis AJ 

Prevention of Cardiovascular Diseases 

European health public1997; 34: 4-5. 

14. Manolis AJ, Beldekos D, Hatzissavas J, Foussas S, Cokkinos D, Bresnaham M, 

Gavras I, Gavras H: Hemodynamic and humoral correlates in essential 

Hypertension. Relationship between patterns of LVH and ischemic changes in 

ETT. Hypertension 30 (part 2) 1997;30:730-734 

15. Manolis AJ, Olympios C, Sifaki M, Smirnioudis N, Handanis S, Argirakis S, 

Katsaros C, Gavras I, Gavras H: Chronic sympathetic suppression in the treatment 

of chronic congestive heart failure. Journal of Clinical and Experimental 

Hypertension 1998;20: 717-731 

16. Manolis AJ, Beldekos D, Handanis S, Haralabidis G, Hatzissavas J, Foussas S, 

Cokkinos D, Bresnahan M, Gavras I, Gavras H: Comparison of Spirapril, 

Isradipine or combination in hypertensive patients with LVH: Effects on LVH 

regression and arrythmogenic propensity. American Journal of Hypertension 

1998;11:640-648. 

17. Manolis AJ, Beldekos D, Hatzissavas S, Foussas S, Cokkinos D, Bresnaham M, 

Gavras I, Gavras H: Hypertension, LVH, and Exercise Myocardial Ischemia. 

International Trends in Hypertension 1998;4:11 . 

18. Baldwin CT, Schwartz F, Burzstyn M, DeStefano A, Gavras I, Handy D, Martel 

T, Joost O, Manolis AJ, Nicolaou M, Bresnaham M, Farrer L, Gavras H: 

Identification of a polymorphic glutamic acid stretch in the α2B adrenergic receptor 

and lack of association with essential hypertension. American Journal of 

Hypertension, 1999;12:853-857. 

19. Baima J, Nicolaou M, Schwartz F, DeStefano A, Gavras I, Manolis AJ, Laffer 

C, Elijovich F, Farrer L, Baldwin CT, Gavras H: Evidence for linkage between 

Essential Hypertension and a Putative Locus on Human Chromosome 17 in 

Caucasian Americans. Hypertension, 1999;34:4-7 

20. Gavras I, A.J.Manolis, Gavras H:Genetic Epidemiology of Essential 

hypertension. Journal of Human Hypertension 1999;13:225-229. 

21. I.Gavras, A.J.Manolis, H.Gavras. The Economics of Therapeutic Advances – 

12

The Paradigm of Sympathetic Suppression in Chronic Heart Failure. Archives 

Internal of Medicine 1999;159:2634-2636 (Abs). 

22. Manolis AJ, Tsalopoulos E, Ramos C, Katsaros K, Dalabiras P, Hatzissavas J, 

Foussas S, Gavras I, Bresnahan M, Gavras H: Benefits of Central Sympathetic 

Suppression with Clonidine after acute myocardial infarction. Advances in Therpay 

1999, 16:272-282 

23. Nicolaou M, Gavras I, Cupples LA, Manolis AJ, Baldwin CT, Gavras H, 

Farrer LA: Genetic predisposition to stroke in relatives of hypertensives. Stroke 

2000;31:487-492. 

24. A.J Manolis, E.Grossman, B.Jelakovic, A.Jacovides, D.Bernhardi, W.Cabrera, 

L.Watanabe, J.Barragan, N.Matadamas, A.Mendiola, K.S.Woo, J.Zhu, A.Mejia, 

T.Bunt, T.Dumortier, R.Smith, on behalf of the Losartan Trial Investigators: 

Effects of Losartan and Candesartan Monotherapy and Losartan 

/Hydrochlorothiazide Combination Therapy in Patients with Mild to Moderate 

Hypertension. Clinical Therapeutics 2000;22:1186-1203. 

25. Stefanadis C, Manolis AJ, Dernellis J, Tsioufis C, Tsiamis E, Gavras H, 

Toutouzas P. Acute Effect of Clonidine on Left Ventricular Pressure-Volume 

Relation in Hypertensive Patients with Diastolic heart Dysfunction. J.Human 

Hypertension 2001; 15: 635-642. 

26. A.DeStefano, H.Gavras, N.Heard, M.Bursztyn, Manolis AJ, L.Farrer, 

C.Baldwin, I.Gavras, F.Schwartz . Maternal Component in the Familial 

Aggregation of Hypertension, Clinical Genetics 2001;60:13-21. 

27. Smith R, Aurup P, Manolis AJ: Antihypertensive Effects of Losartan 

and Candesartan. Clinical Therapeutics 2001;23:516-517. 

28. Gavras I, Manolis A.J, Gavras H. The alpha 2 adrenergic receptors in 

hypertension and heart failure: experimental and clinical studies. Journal Hypertension 

2001;19:2115-2124. 

29. Tonstad S, Farsang C, Klaene G, Lewis K, Manolis AJ, Perruchoud AP, Silagy S, 

van Spiegel PI, Astbury C, Hider A, Sweet R. Bupropion SR for smoking cessation 

in smokers with cardiovascular diasease: a multicentere, randomised study. 

European Heart Journal 2003,24:946-955 

30. Cui J, Zhou X, Chazaro I, DeStefano A, Manolis AJ, Baldwin CT, Gavras H. 

Association of polymorphisms in the promoter region of the PNMT gene with 

essential hypertension in african americans but not in whites. 

American Journal of Hypertension 2003;16:859-863 

31. Voudris V, Avramides D, Gatzov P, Malakos J, Skoularigis J, Manolis AJ, Gavras 

13

H, Gavra I, Cokkinos DV. The effect of rapid decreases of blood pressure by 

different mechanisms on coronary flow and flow reserve in normal coronary 

arteries. American Journal Hypertension 2003;16:1000-1005 

32. Schwartz F, Duka A, Sun F, Manolis AJ, Gavras H. Mitochondrial genome 

mutations in hypertensive individuals. American Journal of Hypertension 2004; 

17:629-635 

33. Manolis AJ, J. Reid, D. de Zeeuw, M. Murphy, E. Seewaldt-Becker, J. Koster. 

Angiotensin II receptor antagonist telmisartan in isolated systolic hypertension 

(ARAMIS) study: efficacy and safety of telmisartan 20, 40 or 80 mg versus 

hydrochlorothiazide 12.5 mg or placebo. Journal of Hypertension 2004, 22:1033-7 

34. G. Kolovou, K. Anagnostopoulou, A. Pavlidis, K. Salpea, S. Iraklianou, K. 

Tsarpalis, D. Damaskos, Manolis AJ, D. Cokkinos. Postprandial lipemia in men 

with metabolic syndrome, hypertensives and healthy subjects. Lipids Health Dis 

2005; 4:21 

35. Cui J, Melista E, Chazaro I, Zhang Y, Zhou X, Manolis AJ, Baldwin CT,. DeStefano 

AI, Gavras H. Sequence vaiation of bradykinin receptors B1 and B2 and 

association with hypertension. Journal of Hypertension 2005; 23:55-62 

36. Stergiou, Th. Makris, M. Papavasileiou, S. Efstathiou, Manolis AJ. Comparison of 

antihypertensive effects of a angiotensin converting enzyme inhibitor, a calcium 

antagonist and a diuretic in patients with hypertension not controlled by angiotensin 

receptor blocker monotherapy. Journal of Hypertension 2005; 23:55-62 

37. Manolis AJ. Exercise and hypertension. Journal of Hypertension 2005;23:23 

38. Manolis AJ, S Iraklianou, A. Pittaras, M. Zaris, K. Tsioufis, G. Psaltiras, D. Psomali, 

S. Foussas, I. Gavras, H. Gavras. Arterial compliance changes in diabetic 

normotensive patients after angiotensin converting enzyme inhibition therapy.Am. 

J. of Hypertension 2005; 18:18-22 

39. Zhou XF, Cui J, DeStefano AL, Chazaro I, Farrer LA, Manolis AJ, Gavras H, 

Baldwin CT. Polymorphisms in the promoter region of catalase gene and essential 

hypertension. Dis Markers 2005;21:3-7 

40. Russo CJ, Melista E, Cui J, DeStefano AL, Bakris GL, Manolis AJ, Gavras H, 

Baldwin CT. Association of NEDD4L ubiquitin ligase with essential hypertension 

Hypertension 2005;46:488-491 

41. Vogt L, Navis G, Koster J, Manolis AJ, Reid JL, de Zeeuw D. Angiotensin II 

receptor antagonist telmisartan in isolated systolic hypertension (ARAMIS) study 

group. J Hypertens. 2005;23:2055-61 

14

42. P. Kokkinos, A. Pittaras, Manolis AJ, D. Panagiotakos, P. Narayan, D. Manjoros, 

R. Amdur, S. Singh. Exercise capacity and 24-h blood pressure in prehypertensive 

men and women. American Journal of Hypertension 2006; 19:251-258 

43 Kolovou GD, Anagnostopoulou KK, Pavlidis AN, Salpea KD, Hoursalas AS, 

Manolis AJ, Cokkinos DV. Postprandial lipaemia in menopausal women with 

metabolic syndrome. Maturitas 2006;55:19-26 

44 Tsioufis C, Dimitriadis K, Taxiarchou E, Vasiliadou C, Chartzoulakis G, Tousoulis 

D, Manolis AJ, Stefanidis C, Kallikazaros J. Diverse associations of 

microalbuminuria with C-reactive protein, interleukin 18and soluble CD 40 ligand 

in male essential hypertensive subjects. Am J Hypertens 2006;19:462-6 

45. Hobbs R, Gensini G, Mancini J, Manolis AJ, Bauer B, Bohler S, Genest J, Feldman 

R, Harvey P, Jenssen T, Metcalfe M, Marques da Silva P.. Can combining different 

risk interventions into a single formulation contribute to improved cardiovascular 

disease risk reduction? Rationale and design for an international, open-label 

program to assess the effectiveness of a single pill (amplodipine/atorvastatin) to 

attain recommended target levels for blood pressure and lipids ( The JEWEL 

Program). Int J Cardiol 2006:110:242-250 

46. P. Kokkinos, A. Pittaras, P. Narayan, C. Faselis, S, Singh, Manolis AJ. Exedrcise 

capacity and blood pressure associations with left ventricular mass in 

prehypertensive individuals. Hypertension 2007;49:55-61 

47. Manolis AJ, M. Doumas, M. Viigimaaa, K. Narkiewicz. Hypertension and sexual 

dysfunction. Journal of Hypertension 2007; 25:8 

48. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagard R, Germano G, Grassi 

G, Heagerty AM, Kjeldsen S, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, 

Scmhieder R, Struizker-Boudier HA, Zanchetti A, Vahanian A, Camm J, De 

Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemans I, 

Dalby Kristensen Sm Mcgregor K, Sechtem U, Silber S, Tendera M, Widimsky P, 

Zamorano JL, Erdine S, Kiowski W, Agabiti-Rosei E, Ambrosioni E, Lindholm 

LH, Manolis AJ, Nillson PM, Redon J, Viigimaa M. Linee Guida della Societa 

Europea; di Ipertensione Arteriosa; Societa Europea di Cardiologia. G Ital Cardiol 

2007;8(7):389-479. 

49. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagart R, Germano G, Grassi 

G, Heagerty Am, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, 

Schmieder RE, Struijker Boudier HA, Zanchetti A, Vahanian A, Camm J, De 

Caterina R, Dean V, Dickstein K, Filippatos G, Funck-Brentano C, Hellemas I, 

Kristensen SD, McGregor K, Sechtem U, Silber S, tendera M, Widimsky P, 

Zamorano JL, Kjeldsen SE, Erdine S, Narkiewicz K, Kioski W, Agabiti-Rosei E, 

15

Ambrosioni E, Cifkova R, Dominiczak A, Fagard R, Heagerty Am, Laurent S, 

Lindholm LH, Mancia G, Manolis A, Nillson PM, redon J, Schmieder RE, 

Struijker-Boudier HA, Viigimaa M, Filippatos G, Adamopoulos S, Agapiti-Rosei 

E, Ambrosioni E, Bertomeu V, Clement D, Erdine S, Farsang C, Gaita D, Kiowski 

W, Lip G, Mallion JM, Manolis Aj, Nillson PM, O’Brien E, Ponikowski P, Redon 

J, Ruschitzka F, Tamargo J, van Zwieren P, Viigimaa M, Waeber B, Williams B, 

Zamorano JL. 2007 Guidelines for the management of arterial hypertension 

ESH/ESC task force on the management of arterial hypertension. Eur Heart Journal 

2007;28:1462-1536 

50. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagart R, Germano G, Grassi 

G, Heagerty Am, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, 






Lindholm LH, Mancia G, Manolis A, Nillson PM, redon J, Schmieder RE, 

Struijker-Boudier HA, Viigimaa M, Filippatos G, Adamopoulos S, Agapiti-Rosei 

E, Ambrosioni E, Bertomeu V, Clement D, Erdine S, Farsang C, Gaita D, Kiowski 

W, Lip G, Mallion JM, Manolis Aj, Nillson PM, O’Brien E, Ponikowski P, Redon 

J, Ruschitzka F, Tamargo J, van Zwieren P, Viigimaa M, Waeber B, Williams B, 

Zamorano JL. 2007 Guidelines for the management of arterial hypertension. 

ESH/ESC task force on the management of arterial hypertension. J. Hypertension 

2007;25:1105-1187 

51. Authors/Task Force Members, Graham I, Atar D, Borch-Johnsen K, Boysen G, 

Burell G, Cifkova R, Dallongeville J, De Backer G, Ebrahim S, Gjelsvik B, 

Herrmann-Lingen C, Hoes A, Humphries S, Knapton M, Perk J, Priori SG, Pyorala 

K, Reiner Z, Ruilope L, Sans-Menendez S, Reimer WS, Weinssberg P, Wood D, 

Yarnell J, Zamorano JL; Other experts who contributed to parts of the guidelines:, 

Walma E, Fitzgerald T, Cooney MT, Dudina A; European Society of Cardiology 

(ESC) 

Committee for Practise Guidelines (CPG):, Vahanian A, Gamm J, e Caterina R, 

Dean V, Dickstein K, Funck-Brentano C, Filippatos G, Hellemans I, Kristensen 

SD, McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL; 

Document reviewers:, Hellemans I, Altiner A, Bonora E, Durrington PN, Fagard R, 

Giampaoli S, Hemingway H, Hakansoon J, Kjeldsen SE, Larsen ML, Mancia G, 

Manolis AJ, Orth-Gomer K, Pedersen T, Rayner M, Ryden L, Sammut M, 

Schneiderman N, Stalenhoef AF, Tokgozoglu L, Wiklund O, Zambelas A 

Joint European Societies Guidelines on CVD Prevention. Eur Heart Journal;2007; 

28:1462-536 

16

52. Graham I, Atar D, Borch-Johnsen K, Boysen G, Burell G, Cifkova R, Dallongeville 

J, De Backer G, Ebrahim S, Gjelsvik B, Herrmann-Lingen C, Hoes A, Humphries S, 

Knapton M, Perk J, Priori SG, Pyorala K, Reiner Z, Ruilope L, Sans-Menendez S, 

Op Reimer WS, Weissberg P, Wood D, Yarnell J, Zamorano JL, Walma E, 

Fitzgerald T, Cooney MT, Dudina A, Vahanian A, Camm J, De Caterina R, Dean V, 

Dickstein K, Funck-Brentano C, Filippatos G, Hellemans I, Kristensen SD, 

McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Altiner 

A, Bonora E, Durrington PN, Fagard R, Giampaoli S, Hemingway H, Hakansson J, 

Kjeldsen SE, Larsen L, Mancia G, Manolis AJ, Orth-Gomer K, Pedersen T, Rayner 

M, Ryden L, Sammut M, Schneiderman N, Stalenhoef AF, Tokgözoglu L, Wiklund 

O, Zampelas A; European Society of Cardiology (ESC); European Association for 

Cardiovascular Prevention and Rehabilitation (EACPR); Council on Cardiovascular 

Nursing; European Association for Study of Diabetes (EASD); International 

Diabetes Federation Europe (IDF-Europe); European Stroke Initiative (EUSI); 

Society of Behavioural Medicine (ISBM); European Society of Hypertension (ESH); 

WONCA Europe (European Society of General Practice/Family Medicine); 

European Heart Network (EHN); European Atherosclerosis Society (EAS). 

European guidelines on cardiovascular disease prevention in clinical practice: full 

text. Fourth Joint Task Force of the European Society of Cardiology and other 

societies on cardiovascular disease prevention in clinical practice (constituted by 

representatives of nine societies and by invited experts). 

Eur J Cardiovasc Prev Rehabil. 2007 Suppl 2:S1-113 

53. Graham I, Atar D, Borch-Johnsen K, Boysen G, Burell G, Cifkova R, Dallongeville 

J, De Backer G, Ebrahim S, Gjelsvik B, Herrmann-Lingen C, Hoes A, Humphries S, 

Knapton M, Perk J, Priori SG, Pyorala K, Reiner Z, Ruilope L, Sans-Menendez S, 

Op Reimer WS, Weissberg P, Wood D, Yarnell J, Zamorano JL, Walma E, 

Fitzgerald T, Cooney MT, Dudina A, Vahanian A, Camm J, De Caterina R, Dean V, 

Dickstein K, Funck-Brentano C, Filippatos G, Hellemans I, Kristensen SD, 

McGregor K, Sechtem U, Silber S, Tendera M, Widimsky P, Zamorano JL, Altiner 

A, Bonora E, Durrington PN, Fagard R, Giampaoli S, Hemingway H, Hakansson J, 

Kjeldsen SE, Larsen ML, Mancia G, Manolis AJ, Orth-Gomer K, Pedersen T, 

Rayner M, Ryden L, Sammut M, Schneiderman N, Stalenhoef AF, Tokgözoglu L, 

Wiklund O, Zampelas A; European Society of Cardiology (ESC); European 

Association for Cardiovascular Prevention and Rehabilitation (EACPR); Council on 

Cardiovascular Nursing; European Association for Study of Diabetes (EASD); 

International Diabetes Federation Europe (IDF-Europe); European Stroke Initiative 

(EUSI); International Society of Behavioural Medicine (ISBM); European Society of 

Hypertension (ESH); European Society of General Practice/Family Medicine 

(ESGP/FM/WONCA); European Heart Network (EHN). 

European guidelines on cardiovascular disease prevention in clinical practice: 

executive summary. Fourth Joint Task Force of the European Society of Cardiology 

and other societies on cardiovascular disease prevention in clinical practice 

(constituted by representatives of nine societies and by invited experts). 

Eur J Cardiovasc Prev Rehabil. 2007 Suppl 2:E1-40. 

17

54. Fourth Joint Task Force of the European Society of Cardiology and Other Societies 

on Cardiovascular Disease Prevention in Clinical Practice (Constituted by 

representatives of nine societies and by invited experts), Graham I, Atar D, Borch- 

Johnsen K, Boysen G, Burell G, Cifkova R, Dallongeville J, De Backer G, Ebrahim 

S, Gjelsvik B, Herrmann-Lingen C, Hoes A, Humphries S, Knapton M, Perk J, Priori 

SG, Pyorala K, Reiner Z, Ruilope L, Sans-Menendez S, Scholte op Reimer W, 

Weissberg P, Wood D, Yarnell J, Zamorano JL; Other experts who contributed to 

parts of the guidelines:, Walma E, Fitzgerald T, Cooney MT, Dudina A; European 

Society of Cardiology (ESC) Committee for Practice Guidelines (CPG), Vahanian A, 

Camm J, De Caterina R, Dean V, Dickstein K, Funck-Brentano C, Filippatos G, 

Hellemans I, Kristensen SD, McGregor K, Sechtem U, Silber S, Tendera M, 

Widimsky P, Zamorano JL, Hellemans I, Altiner A, Bonora E, Durrington PN, 

Fagard R, Giampaoli S, Hemingway H, Hakansson J, Kjeldsen SE, Larsen ML, 

Mancia G, Manolis AJ, Orth-Gomer K, Pedersen T, Rayner M, Ryden L, Sammut 

M, Schneiderman N, Stalenhoef AF, Tokgözoglu L, Wiklund O, Zampelas A. 

European guidelines on cardiovascular disease prevention in clinical practice: 

executive summary. 

Eur Heart J. 2007 (19):2375-414 

55. Mancia G, De Backer G, Dominiczak A, Cifkova R, Fagart R, Germano G, Grassi G, 

Heagerty Am, Kjeldsen SE, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, 






Lindholm LH, Mancia G, Manolis A, Nillson PM, redon J, Schmieder RE, Struijker- 

Boudier HA, Viigimaa M, Filippatos G, Adamopoulos S, Agapiti-Rosei E, 

Ambrosioni E, Bertomeu V, Clement D, Erdine S, Farsang C, Gaita D, Kiowski W, 

Lip G, Mallion JM, Manolis Aj, Nillson PM, O’Brien E, Ponikowski P, Redon J, 

Ruschitzka F, Tamargo J, van Zwieren P, Viigimaa M, Waeber B, Williams B, 

Zamorano JL 

2007 Guidelines for the management of arterial hypertension 

ESH/ESC task force on the management of arterial hypertension 

Blood Pressure 2007;1:135-232 

56. Foussas SG, Zairis MN, Makrygiannis SS, Manousakis SJ, Patsourakos NG, 

Adamopoulou EN, Beldekos DJ, Melidonis AJ, Handanis SM, Manolis AJ, 

Hatzissavas JJ, Argyrakis SK. The impact of circulating total homocysteine levels on 

long term cardiovascular mortality in patients with acute coronary syndromes. 

Int J Cardiol 2008; 124:312-8 

57. Parati G, Stergiou GS, Asmar R, Bilo G, de Leeuw P, Imai Y, Kario K, Lurbe E, 

Manolis A, Mengden T, O'Brien E, Ohkubo T, Padfield P, Palatini P, Pickering T, 

18

Redon J, Revera M, Ruilope LM, Shennan A, Staessen JA, Tisler A, Waeber B, 

Zanchetti A, Mancia G; ESH Working Group on Blood Pressure Monitoring 

European Society of Hypertension guidelines for blood pressure monitoring at home: 

a summary report of the Second International Consensus Conference on Home Blood 

Pressure Monitoring. J. Hypertension 2008; 26:1505-26 

58. Kokkinos P., Myers J., Kokkinos JP, Pittaras A., Narayan P., Manolis A., KarasiK 

P., Greenberg M, Papademetriou V., Singh S. 

Exercise capacity and mortality in black and white men. Circulation 2008; 117:614- 

22 

59. Thomopoulos K, Tsioufis K, Dimitriadis K, Tsiachris D, Tousoulis D, Manolis AJ, 

Alchanatis M, Kallikazaros I, Stefanadis C. 

Obstructive sleep apnoea syndrome is associated with enhanced sub-clinical 

inflammation and asymmetric dimethyl-arginine levels in hypertensives.J Hum 

Hypertens 2009;23:65-67 

60. Manolis AJ, Doumas M. 

Sexual dysfunction: the prima ballerina of hypertension related quality of life 

complications.J Hypertens 2008;26:2074-2084 

61. Redon J, Cifkova R, laurent S, Nilsson P, Narkiewicz K, Erdine S, Mancia G. 

on behalf of the ESH council Reviewer Manolis A. The metabolic syndrome in 

hypertension: ESH position statement. J Hypertens 2008;26:1891-1900 

62. Kokkinos P, Myers J, Nylen E, Panagiotakos D, Manolis AJ, Pittaras A, Blackman 

M, Jacob-Issac, faselis C, Abella J, Singh S. 

Exercise Capacity and all cause mortality in African-American and Caucasian men 

with type 2 diabetes mellitus. Diabetes Care 2009;32:623-628 

63. Hobbs R, Gensini G, Mancini J, Manolis AJ, Bauer B, Genest J, Feldman R, Harvey 

P, Jenssen T, Marques da Silva P, for the JEWEL Study Group. 

International open-label linked studies to assess the efficacy of a novel dual risk 

factor single-pill (amlodipine/atorvastatin) in attaining recommended blood pressure 

and lipid levels: The JEWEL progamme. Eur J Cardiovasc Prev Rehabil 

2009;16:472-480 

64. Exercise capacity and mortality in hypertensive men with and without additional risk 

factors. 

Kokkinos P, Manolis A, Pittaras A, Doumas M, Gianellou A, Panagiotakos D, 

Faselis C, Narayan P, Singh S, Myers J. Hypertension 2009;53:494-499 

65. Kokkinos P, Myers J, Doumas M, Faselis C, Manolis A, Pittaras A, Kokkinos J, 

Singh S, Fletcher R. 

Exercise capacity and all-cause mortality in prehypertensive men. Am J Hypertens 

2009;22:735-741 

19

66. Kokkinos P, Doumas M, Myers J, Faselis C, Manolis A, Pittaras A, Kokkinos J, 

Papademetriou V, Singh S, Fletcher R. 

A graded association of exercise capacity and all cause mortality in males with high 

normal blood pressure. Blood Pressure 2009;18:261-7 

67. Mancia G, Laurent S, Agabiti-Rosei E, Ambrosioni E, Bournier M, Caulfield M, 

Cifkova R, Clement D, Coca A, Dominiczac A, Erdine S, Fagard R, Farsang C, 

Grassi G, Haller H, Heagerty A, Kjeldsen S, Kiowski W, Mallion M, Manolis A, 

NMarkiewicz K, Nilsson P, Olsen M, Rahu K, Redon J, Rodicio J, Ruilope L, 

Schmieder R, Struijker-Boudier H, van Zwiten P, Vigiimaa M, Zanchetti A. 

Reapraissal of European guidelines on hypertension management: a European 

society of Hypertension task force document. J Hypertens 2009;27:2121-58 

68. Mancia G, laurent S, Agabiti-Rosei E, Ambrosioni E, Bournier M, Caulfield M, 

Cifkova R, Clement D, Coca A, Dominiczac A, Erdine S, Fagard R, Farsang C, Grassi 

G, Haller H, Heagerty A, Kjeldsen S, Kiowski W, Mallion M, Manolis A, 

NMarkiewicz K, Nilsson P, Olsen M, Rahu K, Redon J, Rodicio J, Ruilope L, 

Schmieder R, Struijker-Boudier H, van Zwiten P, Vigiimaa M, Zanchetti A. 

Reapraissal of European guidelines on hypertension management: a European 

society of Hypertension task force document. Blood Pressure 2009;18:308-347 

69. Connoly S, Ezekowitz M, Phil C, Yusuf S, Phil D, Eikelboom J, and the RELY 

steering committee and Investigators Manolis A 

Dabigatran versus Warfarin in patients with atrial fibrillation. N Engl J Med 

2009;361:1139-1151 

70. Kokkinos P, Giannelou A, Manolis A, Pittaras A: 

Physical activity in the prevention and management of high blood pressure. 

Hellenic J Cardiol 2009;50:52-59 

71. Manolis AJ, Marketou M, Gavras I, Gavras H. 

Cardioprotective properties of bradykinin: role of B2 receptor. Hypertension Research 

2010;33:772-777 

72. Manolis A, Erdine S, Borghi C, Tsioufis K. 

Perioperative management of hypertension. J Hypertens 2010;11:48 

73. Kallistratos M, Gianakopoulos A, German V, Manolis A. 

Diagnostic modalities of most common forms of secondary hypertension. Hellenic J 

Cardiol 2010;51:518-529 

74. Kokkinos P, Myers J, Faselis C, panaagiotakos D, Doumas M, Pitaras A, Manolis A, 

Kokkinos J, Karasik P, Greenberg M, Papademitriou V.. Circulation 2010;122:790- 

797 

20

75. Parati G, Stergiou G, Asmar R, Bilo G, de Leewe P, Inku Y, Kario K, Lurbe E, 

Manolis A, Mengden T, O’Brien E, Ohkubo T, Padfield P, Palatini P, Pickering T, 

Redon J, Revera M, Ruilope L, Scenman A, Staessen J, Tisler A, Waeber B, 

Zanchetti A, Mancia G. 

European Society of Hypertension practice guidelines for home blood pressure 

monitoring. J Hum Hypertens 2010;24:779-785 

76. Manolis A, Doumas M, 

Hypertension and sexual dysfunction. Archives of Medical Science 2010;337-350 

77. Papakostantinou E, Triantafilidou D, Panagiotakos D, Koutsovasilis A, Saliaris M, 

Manolis A, Melidonis A, Zambelas A. Eur J Clin Nutrition (2010 in press) 

78. Tsioufis C, Kasiakogias A, Thomopoulos C, Manolis A, Stefanidis C: 

Managing hypertension in obstructive sleep apnea: the interplay of continuous 

positive airway pressure, medication and chronotherapy. J Hypertens 2010;28:875- 

882 

79. Pavlidis A, Giannakopoulos A, Manolis A: 

Iatrogenic Giant Osborn Waves. Circulation 2010;122:00 

80. Pavlidis A, Tsoukas A, Zissimopoulos I, Hesketh G, Patestos D, Manolis A: 

Aortic arch rupture following blunt chest trauma.Echocardiography (2010 in press) 

21

Abstracts in International Meetings with Abstract book in INDEX 

MEDICUS 

1. Kolovou G, Manolis AJ, Tsergis A, Foussas S, Bilianou E, Athanasopoulos 

G,Cokkinos D : 

Management of Hypertensive Crisis with sublingual 

Clonidine,Nifedipine,andCaptopril. 

European Journal of Clinical Investigation 1989, 19:2, 240 (Abs) 

2. Foussas S, Kolovou G, Katsaros C, Manolis AJ, Cokkinos D.: 

Atrial fibrillation in chronic mitral regurgitation of rheumatic or ischaemic aetiology. 

Philippine Journal of Cardiology, 1990:1901. (Abs) 

3. Kolovou G, Manolis AJ, Kapnia E, Katsillis K, Bakirtzis A, Karapata G, 

Giannopoulos Th, Cokkinos D. : 

Comparison of Gemfibrozil and cholestypamine combination to lovastatin in 

hyperlipidemic patients. 

Phillipine Journal of Cardiology, 1990:1514. (Abs) 

4. Kolovou G, Foussas S, Manolis AJ, Bakirtzis A, Bilianou E, Tsakonas 

K, Handanis S, Cokkinos D : 

Sublingual clonidine compared to nifedipine and captopril in the management of 

hypertensive crises. 


5. Karatasakis G, Manolis AJ, Chrisos D, Athanassopoulos G, Cokkinos D. 

Is there a relation between filling abnormalities and ventricular mass in 

hypertension ? 


6. Athanasopoulos G, Manolis AJ, Cokkinos DV: Is the response of 

dobutamine infusion related in prognosis of dilated cardiomyopathy? 

European Heart Journal 1990; 11:427 (Abs). 

7. Manolis AJ, Athanasopoulos G, Karatasakis G, Gavras I, Cokkinos DV 

Gavras H: Pressor hormone profile during stress in hypertension with or without 

left ventricular hypertrophy. 

American Journal Hypertension 1991; 4:(Suppl)50A (Abs). 

8. Athanasopoulos G, Fakiolas K, Manolis AJ, Foussas S, Cokkinos DV: 

First derivative of ECG R wave is related to left ventricular systolic function. 

European Heart Journal 1991; 12-404 (Abs). 

9. Kolovou G, Kafkala K, Hatzissavas J, Bilianou E, Bratsou A, Manolis AJ, 

Christopoulou Cokkinou V, Cokkinos DV: 

Effects diferenciales d’un regime dietetique et de medicaments sur les lipoproteins 

de haute densite (HDL) selon leur niveaux initiaux. 

22

Arch Mal Coeur 1992;85:138 (Abs). 

10. Kolovou G, Fostinis J, Bilianou H, Manolis AJ, Cokkinos DV: 

Lipid lowering drugs. Can monotherapy improve lipid profile? 

II Cuore 1993; 10:4-24 (Abs). 

11. Athanasopoulos G, Manolis AJ, Cokkinos DV: Two-dimensional distribution 

of left ventricular hypertrophy in essential hypertension. Is there any correlation 

with 24 hour blood pressure monitoring? 

II Cuore 1993;10: 4-16 (Abs). 

12. Athanasopoulos G, Manolis AJ, Cokkinos DV: Patterns of two dimensional 

distribution of left ventricular hypertrophy in essential hypertension. Correlation 

with 24h blood pressure monitoring. 

European Heart Journal 1993;14:1664 (Abs). 

13. Manolis AJ, Andonopoulos S, Beldekos D, Kafadogias A, Foussas S, CokkinosDV: 

The effect of Angiotensin Converting Enzyme Inhibitor on Zinc Metabolism. 

American Journal of Hypertension 1994;7:4-34A (Abs). 

14. Athanasopoulos G, Manolis AJ, Foussas S, Cokkinos DV: 

Non uniformity of two dimensional distribution of left ventricular hypertrophy in 

essential hypertension. Correlation with 24 hour blood pressure load. 

American Journal of Hypertension1994;7:4-151(Abs) . 

15. Andonakoudis H, Tsagadopoulos D, Vyssoulis G, Votteas B, Makris T, 

Manolis AJ, Toutouzas P: 

Effects of cilazapril on fibrinogen level in hypertensive patients. Greek 

multicenter cilazapril study. 

Blood Coagulation & Fibrinolysis 1994; 5: 2-21(Abs). 

16. Athanasopoulos G, Manolis AJ, Moutzouridis G, Laskos V, Barakos K, 

Kolovou G, Cokkinos DV: 

Total QRS voltage. Echocardiographic evaluation of its accuracy in diagnosing 

left ventricular hypertrophy. 

JACC 1994;l-370 (Abs). 

17. Athanasopoulos G, Manolis AJ, Kolovou G, Foussas S, Cokkinos DV: 

Contribution of pulmonary venous flow to the evaluation of left ventricular 

diastolic function in essential hypertension. 

Journal of Hypertension 1994; 12:3-798 (Abs). 

18. Athanasopoulos G, Manolis AJ, Kolovou G, Cokkinos DV: Evaluation of 

right ventricular filling in essential hypertension. 

Journal of Hypertension 1994; 12:3-799 (Abs). 

23

19. Manolis AJ, Olympios C, Sifaki M, Handanis S, Bresnahan M, Gavras I, 

Gavras H : Reduction of sympathetic activity in the treatment of congestive 

heart failure. 

Hypertension 1995; 25:1368 (Abs) 

20. Antonakoudis H, Tsagadopoulos D, Votteas V, Makris T, Manolis AJ, 

Vyssoulis G, Toutouzas P: 

Effect of Antihypertensive Treatment on Lipids 

and Firbinogen. Greek Multicenter Study of Cilazapril. 

Journal of Hypertension 1996 (Abs). 

21. Beldekos D, Manolis AJ, Handanis A, Pittaras S, Argirakis S, Kardasis S, Foussas 

S: 

Regional Distribution on left ventricular hypertrophy in hypertensives, and 

remodelling after successful therapy. 

Israel Journal of Medical Sciences 1996:32, 10-978 (Abs). 

22. Pittaras A.E, Kokkinos P.F, Manolis AJ, Papademetriou V: Predictors of arrhythmias 

in hypertensives undergoing cardiac catheterisation 

Israel Journal of Medical Sciences 1996:32,10,-971 (Abs). 

23. Manolis AJ, Haralambidis E, Adamopoulou N, Kafaltis N, Katsaros K, Hatzissavas 

J, Pittaras A, Foussas S: The effect of Left Ventricular hypertrophy regression on 

late potentials, arrhythmias and heart rate variability. 

Israel Journal of Medical Sciences 1996:32, 10-975 (Abs). 

24. Manolis AJ, Beldekos D, Charalambidis S, Handanis S, Argirakis S, Foussas S, 

Cokkinos D, Gavras E, Gavras H.: The effect of Isradipine, Spirapril, and their 

combination on left ventricular hypertrophy and vasocontractile hormone levels 

Israel Journal of Medical Sciences 1996:32,10-1005 (Abs). 

25. Hatzissavas J, Smirnioudis S, Archodikis G, Manolis AJ, Panagiotopoulos N, 

Fakiolas K, Papadonakos A, Foussas S,: Comparison of front-loaded to multiple 

bolus r-tPA infusion in the treatment of acute myocardial infarction. 

Israel Journal of Medical Sciences 1996:32,10-1035. 

26. Manolis AJ, Olympios C, Sifaki M, Handanis S, Foussas S, Bresnahan M, 

Gavras I, Gavras H: Effects of combined sympathetic suppression and angiotensin 

converting enzyme (ACE) inhibition in congestive heart failure (CHF). 

Hypertension 1996, 28:510 (Abs). 

27. Manolis AJ, Olympios C, Sifaki M, Handanis S, Argirakis S, Katsaros C, 

Gavras I, Gavras H: Chronic Sympathetic Suppression in the treatment of chronic 

congestive heart failure. 

Hypertension 1997, 29:939 (Abs) 

24

28. Manolis AJ, Beldekos D, Hatzissavas J, Foussas S, Cokkinos D, Bresnaham 

M,Gavras I, Gavras H: 

Hemodynamic and hormonal correlates in essential Hypertension. 

Hypertension 1997;29:95 (Abs). 

29. Manolis AJ, Tsalopoulos E, Ramos C, Katsaros K, Dalabiras P, Hatzissavas 

J,Foussas S, Gavras I, Gavras H: Benefits of central sympathetic suppression with 

clonidine after acute myocardial infarction. 

Circulation 1998 :98, 2347 (Abs) 

30. Manolis AJ: Integrative Mechanisms in Congestive Heart Failure. 

American Journal of Hypertension 1998;11:236 (Abs). 

31. Manolis AJ, Papavassiliou M, Lazaridis A, Tsakiris A, Vyssoulis G, Toutouzas 

Greek Multicenter Study: Antihypertensive Treatment improves the Ankle/Arm 

Blood Pressure Index in patients with Essential Hypertension. 

American Journal of Hypertension 1998;11:123 (Abs.) 

32. Baima J, Nicolaou M, Schwartz F, DeStefano A, Gavras I, Manolis AJ, Farrer 

L,Baldwin C, Gavras H: Evidence of linkage between essential hypertension and 

a putative loci on human chromosome 17 in caucasian Americans. 

Hypertension 1999;33:4-26 (Abs). 

33. Manolis AJ, Hatziioakim G, Pittaras A, Haralambidis G, Hatzigeorgiou S, 

Zairis M, Foussas S, Bresnaham M, Gavras I, Gavras H: Patterns of 

neurohormonal activation in cardiovascular diseases. 

European Journal of Heart Failure 1999;67:182 (Abs). 

34. Manolis AJ, Katsaros K, Pittaras A, Haralambidis G, Hatziioakim G, PsarasG, 

Rammos C, Foussas S, Bresnahan M, Gavras I, Gavras H. Neurohormonal 

activation and heart rate variability in cardiovascular diseases. 

European Heart Journal 1999;20:2966 (Abs). 

35. Manolis AJ, Hatziioakim G, Pittaras A, Haralabidis G, Hatzigeorgiou S, 

Zairis M, Foussas S, Bresnaham M, Gavras I, Gavras H : Patterns of 

Neurohormonal activation in cardiovascular diseases. 

European Journal Heart Failure 1999; 1-67. (Abs). 

36. Manolis AJ, Katsaros K, Pittaras A, Haralabidis G, Hatziioakim G, PsarasG, 

Rammos C, Foussas S, Bresnahan M, Gavras I, Gavras H : Neurohormonal 

activation and heart rate variability in cardiovascular diseases. 

European Heart Journal 1999, 20:570. (Abs). 

37. Manolis AJ, Dernelis J, Stefanadis C, Gavras I, Gavras H, Toutouzas P. 

Accute effect of clonidine on left ventricular pressure volume relation in 

hypertensives with diastolic heart dysfunction. 

25

Hypertension 1999, 33: 27 (Abs). 

38. Baldwin CT, Schwartz F, Baima J, Bursztyn M, DeStefano A, Gavras I, 

Handy D, Joost O, Martel T, Manolis AJ, Nicolaou M, Bresnahan M, Farrer L, 

Gavras H : Identification of a Polymorphic Glutamic Acid Stretch in the a2- 

adrenergic receptor and lack of linkage with essential hypertension. 

American Journal Hypertension 1999, 12:853-857 (Abs). 

39. De Stefano A, Gavras H, Heard N, Burstzyn M, Manolis AJ, Farrer L, 

Baldwin C, Gavras I, Schwartz F. Maternal component of the Inheritance of 

Hypertension 

Hypertension 2000: 34, 138 (Abs) 

40. Pittaras A, Kokkinos P,Manolis AJ, et al. 

Increased mortality in African-American men with coronary heart disease treated with 

nifedipine 

Hellenic Cardiology Journal 2001;171 

41. A. Pittaras, P. Kokkinos, P. Narayan, A.J. Manolis, V. Papademetriou: 

Increased mortality in African-American men with coronary heart disease 

treated with nifedipine. 

European heart Journal 2001, 22:3349(Abs) 

42. S Tonstad, C. Frasang, A.J. Manolis, C. Astbury, A. Hider, R. Sweet: 

Zyban is an effective and well tolerated aid to smoking cessation in 

smokers with cardiovascular disease. 

European Heart Journal 2001, 22:1460(Abs) 

43. A.J.Manolis, D. Psomali, A. Pittaras, A. Loukatzikou, D. Beldekos, E. 

Karagianni, S. Foussas, M. Bresnaham, I. Gavras, H. Gavras: Comparison 

of Diltiazem-Sr vs Amlodipine on resting and stimulated blood pressure, 

catecholamines and diastolic dysfunction in patients with mild to moderate 

essential hypertension. 

American Journal Hypertension 2001, 14:220(Abs) 

44. A.J Manolis, J.L. Reid, D. de Zeeuw, M. Murphy, on behalf of the 

ARAMIS study Group: Angiotensin II receptor antagonist Micardis in 

isolated systolic hypertension (ARAMIS ) study:Efficacy and safety of 

Telmisartan 20, 40, or 80 mg versus Hydrochlrothiazide or placebo 

Journal of Hypertension 2001, 19:2154(Abs) 

45. Pittaras A.E, Kokkinos PF, Narayan P, Manolis A.J, Papademetriou V. 

Exercise blood pressure threshold for left ventricular hypertrophy in normotensive 

and hypertensive middle aged-men 

26

Journal of Hypertension 2002, Vol 20:1317 (Abs) 

46. Iraklianou S, Manolis A.J, Volonakis I, Pittaras A.E, Psaltiras G, 

Loukatzikou I, Foussas S. 

Arterial Compliance improves in diabetic, normotensive patients after ace- 

inhibition therapy 

American Journal of Hypertension 2002, Vol 15:119. 

47. Pittaras A, Kokkinos PF, Narayan P, Manolis AJ, Fletcher R, 

Papademitriou V. 

The b-blocker therapy improves the increased mortality in African Americans 

with coronary heart disease tretment with calcium channel blockers. 

European Heart Journal 2002 Vol 23:1215 

48. Zairis M, Papadaki O, Makriyannis S, Ampatzidou O, Batika P, Manolis AJ, 

Beldekos D, Festeridou C, Kassinos N, Handanis S, Papadonakos A, 

Foussas S. 

Influence of diabetes mellitus on intravenous thrombolysis effectiveness in 

patients with ST elevation myocardial infarction. 

JACC 2003, vol 41: 1049-110 

49. Manolis AJ, Iraklianou S, Pittaras A, Zairis M, Psaltiras G, Loukatzikou I, 

Koutsi K, Koutsouridaki M, Foussas S. 

Arterial compliance changes in diabetic normotensive patients 

after angiotensin converting enzyme inhibition therapy. 

JACC 2003, vol 41: 1104-51 

50. Pittaras A,Kokkinos P, Manolis AJ, Narayan P et al. 

Fit vs unfit middle-aged men and women have lower left ventricular mass 24- 

Hr and exercise blood pressure.Circulation 2003;108(17):3515 

51. Pittaras A,Kokkinos P, Manolis AJ, Narayan P,Singh S,et al., 

Increased left ventricular mass,24 –hour blood pressure and exercise blood pressure 

in unfit versus fit middle-aged men and women 

JACC 2003;35(2);328A 

52. Kokkinos P, Pittaras A,Manolis AJ,et al. 

Exercise blood pressure threshold for left ventricular hypertrophy in normotensive and 

hypertensive middle-aged men. 

J Am Col Cardiol.2002;39(5):237A 

53. Pittaras A, Kokkinos P, Manolis AJ, Narayan P, Singh S, Papademetriou V. 

Lower left vantricular mass, 24-hr blood pressure and exercise blood pressure 

in fit vs unfit middle-aged men and women. 

American Journal of Hypertension 2003, vol 16, 76A 

27

54. Zairis M, Manolis AJ, Lyras A, Psaltiras G, Papadaki O, Foussas S. 

Adequate blood pressure control and long term prognosis following 

coronary stenting 

American Journal of Hypertension 2003, vol 16, 4A 

55. Voudris V, Malakos J, Avramidis D, Gatsov P, Skoularikis J, Cokkinos D, 

Manolis AJ, Gavras I, Gavras H. 

Effect of rapid blood pressure decreases on coronary flow reserve in normal 

coronary arteries 

American journal of Hypertension 2003, vol 16, 21A 

56. Zairis M, Manolis AJ, Kardoulas A, Ampatzidou O, Makrygiannis S, Kouzanidis J, 

Olympios C, Foussas SG, 

Continous 12-lead ST monitoring and long-term prognosis following succesful 

coronary stenting: four years follow-up in GENERATION study. 

European Heart Journal 2003 (Abs) 

57. Pittaras A, Kokkinos P, Manolis AJ, Narayan P, Singh S, Fletcher RD, 

Papademetriou V 

Increased left-verticular mass, 24-hour blood pressure and exercise blood presure 

in unfit versus fit middle-aged men and women 


58. Zairis M, Thoma M, Makrygiannis S, Papadakie O, Katsaros K, 

Manolis AJ, Argyrakis S, Foussas SG 

Type 2 diabetes mellitus and ST-elevation myocardial infarction. Is there the need for 

redefinition of succesful thrombolysis in diabetics? 


59. Gavras I, Voudris V, Avramidis D, Gatzov PM, Malakos J, Manolis AJ, 

Gavras H, Kokkinos D 

The differing effects of hypotensive medications on coronary flow in normal 

coronary arteries: favorable characteristics of clonidine. 


60. Zairis M, Manolis AJ, Lyras AG, Psarogianni P, Batika PC, Foussas SG 

The role of adequate blood pressure control on long term prognosis after 

Successful Coronary stenting. 

Journal of Hypertension 2003 (Abs) 

61. Pittaras A, Kokkinos P, Manolis AJ, Papademetriou V 

Unfit middle-aged men and women have increased left ventricular mass, 24-hr 

blood pressure and exercise blood pressure. 


62. Pittaras A, Kokkinos P, Manolis AJ, Narayan P, Singh S, Papademetriou V. 

28

Fit vs unfit middle-aged men and women have lower left ventricular mass 24-hr 

and exercise blood pressure. 

Circulation 2003 (Abs) 

63. Stergiou G, Makris T, Papavasiliou M, Efstahiou S, Votteas V, Foussas S, 

Achimastos A, Manolis AJ. 

Additive effects of an ACE-I vs a calcium antagonist vs a diuretic in hypertensive 

patients ubncontrolled in angiotensin receptor blocker monotherapy. 


64. Pittaras A, Kokkinos P, Papademetriou V, Narayan P, Matjoros D, Kolovou G, 

Singh S, Manolis AJ. 

Abnormal exercise blood pressure predicts left ventricular hypertrophy in 

prehypertensives 


65. Kolovou G, Anagnostopoulou K, Pavlides A, Salpea K, Iraklianou S, 

Tsapralis K, Pittaras A, Manolis AJ, Cokkinos DV. 

Postprandial differences in men with metabolic syndrome, hypertensives 

and healthy 

Journal of Hypertension 2005 (Abs). 

66. Pittaras A,Kokkinos P,Manolis AJ,et al. 

Non –dippers compared to dippers in pre-hypertension and hypertension have higher 

incidence of abnormal exercise blood pressure response,left ventricular hypertrophy 

and diastolic dysfunction. 

Circulation 2005;112(17):2870 

67. Pittaras A, Kokkinos P, Narayan P, Kolovou G, Papademetriou V, Signh S, 

Manolis AJ 

The incidence of abnormal exercise blood pressure response, left ventricular 

hypertrophy and diastolic dysfunction is higher in pre and hypertensive men. 


68. S.G.Foussas,M.Zairis,M.Bitza, G.Bibis,V.Panagiotidis,S.Makrygiannis, 

A.J.Manolis, D.V.Cokkinos on behalf of the BIAS Study Group. Tzanio 

Hospital, Cardiology Dept, Piraeus, Greece;Piraeus Greece;Onassis Cardiac 

Surgery Center, Cardiology Dept.,Athens, Greece. 

The impact of plasma uric acid levels on the long-term cardiovascular mortality 

in patients with acute coronary syndromes. 

69. N. Patsourakos , M. Zairis, C. Apostolatos, J. Papadopoulos, D. Xenos, L. 

Stefanatos, A. J. Manolis, D.V. Cokkinos, S.G. Foussas. 

Circulating levels of tumour necrosis factor- alpha, brain natriuretic peptide and 

cardiac troponin I upon admission and 31-day mortality in patients with acute 

decompensated chronic heart failure. 

29

ESC 2006, European Heart Journal, P569. 

70. P. Cokkinos, A. Pittaras, C. Faselis, P. Narayan, . Greenberg, S. Singh, 

A.J.Manolis 

Exercise capacity increases the likelihood of left ventricular hypertrophy in the 

hypertensive men and women. 

European Heart Journal, P1516. 

71.A. Pittaras, P. Cokkinos, A. J. Manolis, S. Singh. 

Nondippers have higher incidence of abnormal exercise blood pressure response 

ventricular hypertrophy diastolic and metabolic dysfunction in prehypertensive 

and hypertensive men. 

AJH, 2005, vol. 18, No. 5, part 2, P.99. MP.18. 

72. P. Kokkinos , A. J. Manolis 

Exercise capacity is associated with lower mortality risk in African –Americans 

than Caucasians with type 2 diabetes. 

AHA scientific sessions 2007, OR. 3786 

73.A. Pittaras, P. Cokkinos, A. J. Manolis, P. Narayan, S. Singh, V. Papadimitriou 

Left Ventricular hypertrophy in hypertensive African –Americans with coronary 

artery disease increases the 10year mortality risk. 

AJH –May 2004- vol. 17, No. 5, part 2, OR -62 

74. A. Pittaras, P. Cokkinos, A. J. Manolis, P. Narayan, D. Manjoros. 

Abnormal exercise blood pressure predicts left ventricular mass in pre- 

hypertensive, middle –aged men and women. 

AJH –May 2004- vol. 18, No. 5, part 2, P. 507 

75.Zisimopoulos I., Tsoukas A. , PapagiannisN., Konti Z, Andreadis A, Flouda E, 

Koliandris I, Manolis A.J. 

Demonstration of traumatic injury of the thoracic aorta in patients with blunt 

chest trauma. 

Abstract book of 1 st International Congress on Hypertension and Cardiovascular 

Prevention. Rhodes, Greece, June 28- July 1, 2007. 

Pg. 110, P034 

76. Tsoukas A., Zisimopoulos I., Andonakoudis G., Anastasopoulou E., Stamou E., 

Blazakis G., Koliandris I., Manolis A.J 

Aortic arch thrombus detected by transesophageal echocardiography. 



Pg. 111, P035 

77. A. Tsoukas, I. Zisimopoulos, N. Papagiannis, Z. Konti, G. Andonakoudis, E. 

Flouda, I. Koliandris, A.J.Manolis. 

30

Pulmonary embolism of a large right atrial thrombus. 



Pg. 49. 

78 A.J. Manolis, E. Melista, A. Loukatzidou, A. Pittaras, E. Adamopoulou, M. 

Zairis, N. Kouremenos, J. Cui, C. Baldwin, H. Gavras. 

Genetic analysis of hypertension in greek population. 

Abstract book of the 16 th European Meeting on Hypertension. Madrid , June 

12-15, 2006. Poster session P16, P.88. 

79..Kokkinos P, Pittaras A, Manolis A.J.,et al. 

Exercise capacity and 24-hr blood pressure in pre-hypertensive men and 

women. 

Am J Hypertension 2006;19:251-258 

80. E. Melista, A.J. Manolis, A. Loukatzidou, E. Karagianni, A. Pittaras, I. 

Loukatzidou, M. Zairis, S. Leonidi, E. Adamopoulou, J. Cui, C. Baldwin, H. 

Gavras. 

Role of family history in the prevalence of hypertension. 



81. E. N. Adamopoulou, M. N. Zairis, A.J. Manolis, P. Batika – Zairi, 

V. Tsirimbis, 

N. Kouremenos, S.G. Foussas. 

The impact of brain natriuretic peptide on the long term prognosis after non st 

acute coronary syndromes in hypertensives. 



82. A. Pittaras, P. Kokkinos, S. Singh, A.J.Manolis 

Nondippers have higher incidence of abnormal exercise blood pressure response 

ventricular hypertrophy diastolic and metabolic dysfunction in prehypertensive 

and hypertensive men. 

Abstract book of the 16 th European Meeting on Hypertension. Madrid , June 12- 

15, 2006. Poster session P06, P.400. 

83. A. Pittaras, P. Kokkinos, P. Narayan, S. Leonidi, S. Singh, A.J Manolis. 

Left ventricular structure and function and exercise responses in prehypertensive 

women. 



84. M.N. Zairis, A.J. Manolis, E. N. Adamopoulou, N. Patsourakos, P. Batika – Zairi, N. 

Kouremenos, D. Beldekos, S.G. Foussas. 

31

The prognostic role of inflammatory biomarkers in hypertensives and 

normotensives with non st acute coronary syndromes. 



85. A.J. Manolis , A. Pittaras, E. Adamopoulou, D. Beldekos. 

Comparison of antihypertensive effect of different combinations in hypertensives 

not controlled with calcium channel blocker varnidipine as monotherapy. 



86. Pittaras A,Kokkinos P, Manolis AJ et al. 

Non – dippers have higher incidence of abnormal exercise blood pressure response than 

Dippers. 

Eut Heart J 2006;27(667) 

87. Pittaras A,Kokkinos P,Manolis AJ,et al. 

Abnormal exercise blood pressure response,left ventricular hypertrophy and metabolic 

dysfunction in hypertensive and prehypertensive men. 

Eur Heart J 2006; 

27(669) 

88. Gianfranco Parati, Roland Asmar, Grzegorz Bilo, Peter de Leeuw, Yutaka Imai, 

Kazuomi Kario, Empar Lurbe, Athanasios Manolis, Thomas Mengden, Eoin O’ 

Brien, Takayoshi Ohkubo, Paul Padfield, Paolo Palatini, Thomas Pickering, Josep 

Redon, Miriam Revera, Luis M. Ruilope, Andrew Shennan, Jan A. Staessen, 

George Stergiou, Andras Tisler, Bernard Waeber, Alberto Zanchetti and Giuseppe 

Mancia. 

On behalf of the ESH Working Group on Blood Pressure Monitoring. 

Guidelines for the use of self- blood pressure measurement at home. A summary 

report of the 2 nd International Consensus Conference. Verbania, June 14 th , 2007. 

89. Kokkinos P,Myers Jonathan,Kokkinos John Peter,Pittaras A, Manolis AJ,Eric 

Nylen,Joshua Abella,Leon Hsu,Puneet Narayan, Roshney Jacob, and Sreven Singh. 

Exercise Capacity is Associated with Lower Mortality Risk in African-Americans than 

Caucasians with Type 2 diabetes. 

Circulation (Abstract supplement)3786,2007 

90. Andreas Pittaras, Peter Kokkinos, Athanasios Manolis, Konstantinos Kifnidis, 

John Peter Kokkinos, Steven Singh. 

Nondippers have higher incidence of abnormal exercise blood pressure response, 

Left ventricular and carotid structure diastolic dysfunction , and metabolic profile 

in prehypertensive and hypertensive men. 

JCH, 2008, vol. 10, No. 5, suppl. A, p. 80. 

32

91. Andreas E Pittaras, MEDITON, Athens Greece; Athanasios Manolis, Asklipieion 

Voulas Athens, Greece; John Peter Kokkinos, VA & Georgetown Univ Medical 

Ctrs, Washington, DC Vasiliki Kolovou, Antiopi Papada, Ioannis Athanasiadis, 

MEDITON, Athens, Greece; Peter Kokkinos, VA & Gorgetown Univ Medical 

Ctrs, Washington, DC. 

Nondippers Have Higher Incidence of Abnormal Exercise Blood Pressure 

Response Left Ventricular and Carotid Structure Diastolic Dysfunction and 

Metabolic Profile in Pre-Hypertensive and Hypertensive Men. 

American Heart Association May 2,2008;145 

92. Peter Kokkinos, Jonathan Myers, Andreas Pittaras, Athanasios Manolis, 

John Peter Kokkinos, Josua Abella, Puneet Narayan, Charles Faselis, and 

Steve Singh. 

Exercise Capacity is Inversely Associated with Mortality Risk in Pre- 

Hypertensive Men 

Eur Heart Journal 

93.Kokkinos P,Myers, Kokkinos JP,Pittaras A,Narayan P,Manolis A, 

Karasik P,Greenberg M,Papademetriou V,Singh S, 

Exercise Capacity and Mortality in African-American and Caucasian Men. 

Circulation 2008;117:614-622 

94. Kokkinos P, Myers Jonathan , Kokkinos John Peter,Pittaras A, Manolis A.J. 

Joshua Abella, Leon Hsu,Puneet Narayan,Michael Greenberg and Sreven Singh. 

Exercise Capacity is Associated with lower mortality risk in prehypertensive African- 

Americans than Caucasians. 

AHA 48 th Cardiovascular Disease Epidemiology and prevention Annual Conference 

P157,2008. 

95. Gianfranco Parati,George S.Stergiou,Roland Asmar,Grzegorz Bilo, Peter de 

Leeuw,Yutaka Imai,Kazuomi Kario,Empar Lurbe, Manolis Athanasios,Thomas 

Mengden, Eoin O;Brien,Takayoshi Ohkubo, Paul Padfield,Paolo Palatini,Thomas 

Pickering,Josep Redon, et al. 

European Society of Hypertension guidelines for blood pressure monitoring at 

home:a summary report of the second international consensus conference on home 

Blood pressure monitoring 

Journal of Hypertension 2008,vol 26 No 8 

96. Pittaras A, Myers J, Narayan P, ManolisAJ, faselis C, Signh S, Kokkinos P. 

Exercise capacity is inversely associated with mortality in prehypertensive men. 

Circulation 2008 (Abs) 

33

Chapters in Greek Books 

I have published 50 chapters in Greek books 

Chapters in International Books 

1. Female Urology. 

‘Renovascular Hypertension’. 

Athanasios Manolis, Irene Gavras. 

Harry Gavras, 1995. 

2. Hypertension and Atherosclerosis. 

‘Proceedings of 8th Annual Meeting of the Mediterranean Association of 

Cardiology and Cardiac Surgery’. 1996; 119-122 

3.. The Year of Hypertension 2005 

“Hypertension and the heart” 

A.J Manolis, I Gavras 

4. Manual of Hypertension of the European Society of Hypertension 

“Hypertension and associated risk factors” 

A.J Manolis, G. Kolovou 

2008:pp 42-48 

Informa Health Care 

5. Manual of Hypertension of the European Society of Hypertension 

‘The diagnostic approach in uncomplicated and complicated hypertension’. 

Athanasios J. Manolis, K. Tsioufis. 

2008: pp 190-195 

Informa Health Care 

6. Proper workup of a patient with hypertension 

AJ Manolis, G. Mancia 

In press 

Guidelines 

Writing Committee /Reviewer 

1. 2007 Guidelines for the management of arterial hypertension 

ESH/ESC task force on the management of arterial hypertension 

J. Hypertension 2007;25:1105-1187 

Eur Heart Journal 2007;28:1462-1536 

34

2. Self blood pressure measurement at home 

II Consensus 

J. Hypertension 2007: 26:1505-1526 

3. 4 th Joint European Societies Guidelines on CVD Prevention 

Eur Heart Journal;2007: 28:1462-1536 

4. 2009 Guidelines on Atherosclerosis 

. 

Lectures in Greek meetings 

I gave more than 300 lectures in Greek meetings, in coronary artery disease, heart failure, 

and hypertension. 

Lectures in International meetings 

I gave more than 250 lectures since 1992, in coronary artery disease, heart failure and 

mainly hypertension. 

For your information the last year I gave the following lectures in International meeting 

2007 

1. 2007 Advanced Course on Hypertension 

From hypertension to heart failure 

Sestriere, Italy 

2. Laval University/International chair on cardiomedabolic risk 

New ESH/ESC guidelines 

Quebec, Canada 

3. 2007 Master Course on hypertension 

Current news about ESH/ESC guidelines and large clinical trials 

Sofia, Bulgaria 

4. 2007 Master Course on Hypertension 

Assesment of organ damage and total CV risk 

Moscow, Russia 

5. 2007 Master Course on Hypertension 

Assesment of organ damage and total CV risk 

Helsinki, Finland 

35

6. SBPM at home-II Consensus Conference 

Methological aspects 

Verbania, Italy 

7. SBPM at home-II Consensus Conference 

Arrhythmias 

Verbannia, Italy 

8. Selected topics on Hypertension 

Indication for the most effective fixed combination 

Brescia, Italy 

9. European Congress of Cardiology 

Management of patients with hypertension and comorbidities: atrial fibrillation 

Vienna, Austria 

10. Course on High Blood pressure 

Ther role of b-blockers in hypertension 

Riyadh, Saudi Arabia 

11. Course on high Blood Pressure 

The role of b-blockers in Hypertension 

Jeddah, Saudi Arabia 

12. ESH Summer school on Hypertension 

From hypertension to heart failure 

Olympia, Greece 


Combination treatment 



Hypertension and Arrhythmias 


15. Italian Society of Hypertension Annual Meeting 

Metabolic effects of Antihypertensive drugs 

Rome, Italy 

16. 1 st Meeting on Combination treatment 

Which and for whom 

Budapest, Hyngary 

17. Mayo Clinic Course 2007 

36

Hypertension 2007: BHS, ESH, JNC7 Guidelines 

Dubai, UAE 

2008 

18. Combination Treatment and Hypertensive Heart Disease. 

The International Conference on fixed combination in the treatment of 

hypertension and dyslipidemia. 

7-10 February, 2008, Budapest, Hungary. 

19. Hypertension and heart failure. 

ESH Advanced Course on Hypertension. 

1-8 March, 2008, Milano, Italy. 

20. Treatment of associated risk factors. 

Satellite Symposium to the Berlin 2008 Hypertension Meeting. 

31 May, 2008, Gdansk, Poland. 

21. The anti-atherosclerosis action of ACE inhibitors;clinical relevance. 

Prevention and treatment of heart disease: A multifactorial approach. 

28-31 May 2008, Athens, Greece. 

22. 2007 ESC/ESH guidelines: what’s new? 

7 th International Meeting on Nitric Oxide. 

8-9 May 2008, Sharm El Sheikh, Egypt. 

23. Hypertensive heart disease 

2 nd International Meeting on Hypertension and cardiovascular prevention 

27-30 June,2008,Greece 

24. The role of Antihypertensive therapy in cardiovascular prevention 

Congress of the European Society of Cardiology 

3 September 2008, Munich, Germany 

25. Treatment combinations 

ESH summer school 

13 September 2008, Annecy, France 

26. Diagnostic and therapeutic approach in hypertension 

ESH Master Course 

September 2008, Bucurest, Romania 

27. From hypertension to heart failure 

ESH Master Course 

September 2008, Bucurest, Romania 

37

2009 

28. 1 st International symposium on renal dysfunction and cardiovascular disease 

January 2009, Athens, Greece 

29. Egyptian Society of Atherosclerosis meeting 

January 2009, Ras Sudr, Egypy 

30. ESH Advanced course on Hypertension 

7-14 March, 2009, Couramayer, Italy 

31. 6 th International forum on angiotensin II receptor antagonism 

19 March 2009, Lisbon, Portugal 

32. 6 th International forum on angiotensin II receptor antagonism 

20 March 2009, Lisbon, Portugal 

33. 6 th Mediterranean meeting on Hypertension and Atherosclerosis 

25-29 March 2009, Antalya, Turkey 

34. Joint Meeting of American College of cardiology and University of Athens 

4 April 2009, Athens, Greece 

35. ESH Intensive Master Course on Hypertension 

16-17 April 2009, Prague, Czech republic 

36. 4 th European Cardiology Conference for General practicioners 

29-31 May 2009, Istanbul, Turkey 

37. Heart Failure 2009. WG of the European Society of Cardiology 

30 May-2 June 2009, Nice, France 

38. European Society of |Cardiology Meeting 

September 2009, Barcelona, Spain 

39. ESH Summer School 

September 2009, Smolenice, Slovakia 

40. 2 nd International Conference on Fix Combination in the Treatment of 

Hypertension, Dyslipidemia, and Diabetes Mellitus 

10-12 December 2009, Valencia, Spain 

38

“Curiculum Vitae” Athanasios J. Manolis, MD, FACC, FESC, FAHA

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