Southern Medical and Surgical Journal - Georgia Regents University

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1849.] O'KeefFe, on the Properties of Dogwood Bark. 25Case X. Nases, a negro, rail-road hand, aged 32, full plethorichabit. Three weeks since, Imd five paroxysms of quotidianintermittent, fever, treated with quinine.7th Sept., 10^, A.M. Was taken with a chill, succeeded byfever, which lasted all that day. An intermission on the 8th.7, P. M., first visit—expected a recurrence of the paroxysmto-morrow morning. Ordered : Cal. and Jal. aa 15grs. ; Sgrs.Ext. Cor. at 4, A. M., 9th, repeated ei:ery hour till 64 grs. aretaken.9th, 5, P. M. Prescription followed ; has been freely operatedon ;10th.missed the paroxysm, and has no symptom of disease.Convalescent.Case XI. M. C, aged 21, full Ifabit, strong constitution, occupationin the Factory. One week since, she had tertianintermittent of five weeks duration, of which she was cured byquinine, &c.1, P. M., 11th Sept. Had a chill, followed by fever, and at9, A. M., 12th, is found free from fever, but much indisposed.Prescribed: Ca!. and Jal. aa 15 grs.; IQ grs. Ext. Cor. everyhour till 64 grs, are taken. 6, P. M. Has had several evacuations;has taken but 32 grs. of tfie Ext. Cor.; no fever duringthe day. S grs. Ext. Cor. at 8, A.M., 13th, repeated everyhour until 32 grs. are taken.13th, Took the medicine; no fever. Dismissed, convalescent.N. B.—We have had an opportunity of seeing the three lastrecorded cases frequently since their respective time of treatment; we can, therefore, vouch for their radical cure. Nov. 9th.Here we have three cases of intermittent fever recurringunder the hebdomadal form after the quinine treatment, in whichthis tendency is eradicated by the use of the Ext. Cor.—showing,at least as far as they go, the prophylactic virtue of thisarticle.^L-Case 9, offers for our consideration, a tertian intermittent,returning at the fourth hebdomadal period, after an attack ofmalignant intermittent, which shows satisfactorily theefficacyof the Ext. Cor., as well as many of the characteristics of thisaffection, viz.,its liability to recur at hebdomadal periods, inde-
—26 O'Keeffe, on the Properties of Dogwood Bark. [Januarj^pendent of the mode of treatment ;a progressive increase in theintensity of each succeeding paroxysm, which, if not arrestedby medication, mig_ht have assumed the malignant type—as onthe occasion alluded to, the malignant was preceded by twoparoxysms of simple intermittent. On the first administrationof the Ext. in this case, the result obtained could not have beensurpassed by the use of any anti-periodic agent.On cases 10 and 11, we will forbear commenting; but forfurther remarks upon this division of the subject, reference maybe had to our observations on case 2.*There are some other cases which, from having no directrelation to the special points which the preceding cases are respectivelydesigned to elucidate, could not be comprised underany of the three divisions «^bovelaid down, yet they may beworthy of note, as justifying the claims of the Extract of Dogwoodbark to anti-periodic power.Case XII. Mrs. B., oet. 42, of full habit, has had quotidianintermittent fever since 1st Sept.,the time of access being variable.Took, on the 6th, 20 grs. quinine ; notwithstanding theparoxysm returned about 12, at night. At 10, A.M., 7th, theskin is found cool and dry : puFse feeble and frequent ; head-ach^and pain in the lumbar region; great exhaustion and restlessness;tongue slightly furred. Prescription: Sinapism to thespine; 8 grs. Ext. Cor. every hour till 64 grs. are taken.8th, 9, A. M. Has taken the medicine, missed the expectedparoxysm—is much better in every particular. 10 grs. Ext.Cor. at 8, P. M., repeated every hour till 40 grs. are taken.9th. Has taken the medicine ; no fever since last visitconvalescent.Case XIII.Howard, aged 23,' a steam-boat hand, occupationcook, previous health very good, has had intermittent feverof the double-tertian type since August 27th.First saw him 9, A. M., 1st Sept.—had no fever, 4, P. M., beingthe usual time of access.hour till 72 grs. are taken.Ordered, 8 grs. Ext. Cor. every*Tn the four cases of the hebdomadal type which we have given, the immunityfrom subsequent attacks was ascertained by frequently visiting them fromthe period of the first invasion until the present time—November 5th, 1848.
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