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RNA Splicing: Removal of Introns from Primary ... - EURASNET

RNA Splicing: Removal of Introns from Primary ... - EURASNET

RNA Splicing: Removal of Introns from Primary ... - EURASNET

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Cis elements required for splicing5‘ssBP3‘ssYeastGUAUGUUACUAACYAGVertebratesESEAGGUAAGUCURAYYYYY NCAG10-15GUESEPlantsESE?AG GUAAGUCURAYUGYAG GUUA-richUA-rich6210070 49 64 95100 4479 99 58 53 4210057ESE?5‘ss – 5‘ splice site (donor site)3‘ss – 3‘ splice site (acceptor site)BP – branch point (A is branch point base)YYYY 10-15 – polypyrimidine trackY – pyrimidineR – purineN – any base

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