preliminary scientific programme & call for abstracts - International ...

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSInvitation LetterOn behalf of the International Society of Neuroimmunology (ISNI), we are pleasedto invite you to participate in the Eleventh ISNI Congress, which will be held in Boston,USA, from November 4­8, 2012.There are exciting developments in the field of Neuroimmunology affecting ourunderstanding of neuroimmune diseases, the development of new immunotherapies, andnew technology for research.The Organizing Committee, on behalf of the ISNI, is preparing an exciting programthat will inform participants on the latest developments in the field. The program willinclude plenary sessions, focused symposia, and workshops. Plenty of time is devoted toposter presentations. We want to see you there!Boston, one of America’s oldest cities has a rich economic and social history, and ishome to many institutions of higher education, some of the world’s finest hospitals, andnumerous cultural and professional sports organizations. Museums, places to visit andrestaurants in the city will make this event a wonderful experience.We look forward to seeing you in Boston!Samia KhouryConference ChairJack, Sadie and David BreakstoneProfessor of NeurologyHarvard Medical School3

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSISNI ProfileThe first International Congress of Neuroimmunology was held in Stresa, Italy, in 1982 andwas organized by Drs. Peter O. Behan and Federico Spreafico. The second InternationalCongress of Neuroimmunology was held in Philadelphia, PA, and was organised by C.S. Raineand Dale E. McFarlin. It was at this meeting in Philadelphia in 1987 that it was decided tostart an international society, the International Society of Neuroimmunology, and an electionwas held for a panel of officers. C.S. Raine was elected President, John Newsom­Davis VicePresident, Robert Lisak Treasurer and Kenneth Johnson Secretary, together with anInternational Advisory Board. The Society was incorporated in 1988. Subsequent meetingswere in Jerusalem 1991 (Oder Abramsky and Haim Ovadia), Amsterdam 1994 (Kee Lucas),Montreal 1998 (Jack Antel and Trevor Owens), Edinburgh 2001 (John Greenwood, SandraAmor, David Baker, John Fazakerley and Angela Vincent), and Venice 2004 (Francesca Aloisiand Gianvito Martino).Dale McFarlin died unexpectedly in 1992 and the Dale McFarlin Lecture has been a specialfocus of the ISNI meetings since then. Henry McFarland gave the first Dale lecture in 1994(Amsterdam), Martin Raff the second in Montreal (1998), the third by John Newsom­Davisin Edinburgh (2001) and the fourth by Peter Doherty in Venice (2004). The first ISNI Lecturewas given by C. S. Raine in Edinburgh (2001) at the 6 th ISNI Congress, the second by AngeloVescovi in Venice at the 7 th ISNI Congress and the last one in Fort Worth by Larry Steinman.The by­laws were first drafted in 1988 and were then updated and ratified by the GeneralMeeting in Edinburgh in 2001. The by­laws will be sent to all new members of the Society.The principal office of the Society is in Rome, Italy, and the executive office is currentlysupervised by Tomas Olsson (President) in coordination with Gianvito Martino (VicePresident) and Roberto Furlan (Treasurer and Secretary).Since 2010, the European School of Neuroimmunology (ESNI) is the official school of theISNI and the first congress day is dedicated to the ESNI.official website: www.isniweb.org4

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSAbout BostonIt's a big city, but you can cover thecentre on foot in just a couple ofhours. And with the history of theFreedom Trail, the modernattractions of the Institute ofContemporary Art and everything inbetween, Greater Boston is worthexploring for a weekend, and foryears to come.Hop on the T for a quick ride to theKennedy Library and Museum, orstay close to the water for a visit tothe New England Aquarium. Whenyou're ready for a coffee or icecream break, a short walk to theNorth End will put you in the midstof world­class dolci on HanoverStreet. Take the kids to the Children'sMuseum, where they'll have somuch fun they won't even realizehow much they're learning. TheMuseum of Science, where you'llcatch fascinating exhibits — and aDuck Tour, an amphibious vehiclewhich takes you through the city andinto the Charles River.Just across the Charles River inCambridge, enjoy the ethnic cuisine and plentiful bookstores of Harvard Square. If you'rescientifically minded, the MIT Museum will give you a lot to think about.Learn more on: http://www.massvacation.com/greaterBoston/6

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSCommitteesISNI OfficersPresidentVice PresidentSecretary­TreasurerHonorary OfficersJack AntelTrevor OwensCedric S. RaineAngela VincentHartmut WekerleCaroline WhitacreTomas Olsson, SwedenGianvito Martino, ItalyRoberto Furlan, ItalyMontreal, CanadaOdense, DenmarkNew York, NY, USAOxford, UKMartinsried, GermanyColumbus, OH, USAInternational Advisory BoardF. Aloisi Rome, ItalyB. Becher Zürich, SwitzerlandA. Coles Cambridge, UKR. Gold Bochum, GermanyD. Hafler Boston, MA, USAW. Hickey Dartmouth, MA, USAR. Hintzen Rotterdam, The NetherlandsV. Kuchroo Boston, MA, USAR. Martin Zürich, SwitzerlandY. Matsumoto Tokyo, JapanS. Miller Chicago, IL, USAH. Perry Southampton, UKL. Probert Athens, GreeceM. Schwartz Rehovot, IsraelL. Steinman Stanford, CA, USAP. Villoslada Barcelona, SpainT. Yamamura Tokyo, JapanW. Yong Calgary, CanadaA. Uccelli Genoa, Italy7

PRELIMINARY SCIENTIFIC PROGRAMME& CALL FOR ABSTRACTSCongress Organising CommitteeCongress Chair: Samia J. KhouryProfessor of Neurology, Harvard Medical School, Boston, MA, USACo­Director Partners MS Center Jack, Sadie and David BreakstoneDavid A. HaflerProfessor of Neurology, Yale School of Medicine, New Haven, CT, USAVijay KuchrooProfessor of Neurology, Harvard Medical School, Boston, MA, USAAssociate Immunologist at the Brigham and Women’s HospitalSteven JacobsonSenior Investigator, Viral Immunology Section at NIH, Bethesda, MD, USAOrganising SecretariatEEM International Congress Services SrlVia Elio Lampridio Cerva, 167 – 00143 Rome, Italytel. +39 06 5193499 – fax +39 06 5194009e­mail: secretariat@isni2012.org8

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSDates to rememberAbstract submission& Travel Grant application deadline:Abstract acceptance& Travel Grant notification deadline:14 th May201214 th July2012Early registration deadline:30ᵗʰ June2012Official ISNI School of NeuroimmunologyOrganiser of the pre­congress course, the 12ᵗʰ ESNI Course: 4ᵗʰ November, 2012.CoordinatorsGianvito Martino,Hugh Willison,Division of Neuroscience, San Raffaele Hospital, Milan, ItalyDepartment of Neurology, University of Glasgow, UK9

Pre-Congress ESNI CourseISN8:15 am8:30 am9:00 am9:30 am10:00 am10:30 am11:00 am11:30 am12:00 pm12:30 pm1:00 pmSundayNovember 4Morning Session8:15 am8:30 amMondayNovember 5Welcome AddressesMorning Session9:00 am 9:30 am 10:00 am10:30 amConcurrent Symposia11:00 am 11:30 am 12:00 pm12:30 pm1:00 pm8:15 am8:30 am12:30 pm1:00 pmTuNovMor9:00 am 9:30 am10:00 am 10:30 amConcu11:00 am 11:30 am 12:00 pm1:30 pm2:00 pm2:30 pm3:00 pm3:30 pm4:00 pm4:30 pm5:00 pm1:30 pm2:00 pm2:30 pm3:00 pm3:30 pm4:00 pm4:30 pm5:00 pm& Poster Session1:30 pm2:00 pm2:30 pm3:00 pm3:30 pm4:00 pm4:30 pm5:00 pm& Po5:30 pm6:00 pm5:30 pm6:00 pm5:30 pm6:00 pm6:30 pm7:00 pm7:30 pm

I Congress scheduleesdayember 68:15 am8:30 amWednesdayNovember 78:15 am8:30 amThursdayNovember 8ing SessionMorning SessionMorning Session 9:00 am 9:00 am 9:30 am9:30 am 10:00 am10:00 am 10:30 am10:30 amrrent SymposiaConcurrent SymposiaConcurrent Symposia 11:00 am 11:00 am 11:30 am 11:30 am 12:00 pm12:00 pm12:30 pm12:30 pm 1:00 pm1:00 pm1:30 pm1:30 pm 2:00 pm 2:00 pm2:30 pm2:30 pm 3:00 pm3:30 pm3:00 pm3:30 pmster Session4:00 pm4:30 pm5:00 pm5:30 pm6:00 pm& Poster Session

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSSpeakers’ listAmit Bar­Or Neurology and Neurosurgery, McGill University, CanadaBurkhard Becher Institute of Experimental Immunology, University of Zürich, SwitzerlandAlastair Compston Clinical Neuroscience, University of Cambridge, UKJosep Dalmau Neurology, University of Pennsylvania, Philadelphia, PA, USARobert Darnell Investigator, Rockefeller University, New York, NY, USAPhilip L. DeJager Neurology, Brigham and Women's Hospital, Boston, MA, USADouglas Fields Nervous System Development, National Institute of Child Health and Human DevelopmentAlexander Flügel Neuroimmunology, Institute for MS Research, Göttingen, GermanyRoberto Furlan Clinical Neuroimmunology Unit, San Raffaele Scientific Institute, Milan, ItalyNir Hacohen Immunology, Harvard Medical School, Boston, MA, USADavid Hafler Neurology and Immunobiology, Yale University, New Haven, CT, USAHans­Peter Hartung Clinic Neurology, Heinrich­Heine University, Düsseldorf, GermanyStephen Hauser Neurology Dept., University of California, San Francisco, CA, USALudwig Kappos Neurology, University Hospital, Basel, SwitzerlandDimitrios Karussis Neurology, Hadassah Medical Organization, Jerusalem, IsraelLloyd Kasper Neurology, Microbiology and Immunology, Dartmouth, Hanover, NH, USAMartin Kerschensteiner Clinical Neuroimmunology, L. M. University, Münich, GermanyJonathan Kipnis University of Virginia, School of Medicine, Charlottesville, VA, USAZaal Kokaia Lund Stem Cell Center University Hospital, SwedenVijay Kuchroo Neurology, Harvard Medical School, Boston, MA, USAVanda A. Lennon Immunology and Neurology, Mayo Clinic, Rochester, MN, USALinda Liau Neurosurgery, University of California, Los Angeles, CA, USAJeff Lichtman Molecular and Cellular Biology, Harvard Medical School, Boston, MA, USAW. Ian Lipkin Neurology and Pathology, Columbia University, New York, NY, USAChristopher Love Dept. of Chemical Engineering, MIT, Cambridge, MA, USAGianvito Martino Neuroscience, San Raffaele Hospital, Milan, ItalyKingston Mills Immunology Research Center, Trinity College, Dublin, IrelandMichael Platten Neurooncology, University of Heidelberg Medical School, GermanyHidde Ploegh Biology, Whitehead Institute, MIT, Cambridge, MA, USAStefano Pluchino Cambridge Center for Brain Repair and Stem Cell Initiative, UKGabriel Rabinovich Institute of Biology & Experimental Medicine, University of Buenos Aires, Argentina12

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSSerge Rivest Molecular Endocrinology, Laval University, Québec, CanadaAlexander Rudensky Memorial Sloan­Kettering Cancer Center, New York, NY, USAStephen Sawcer Clinical Neuroscience, University of Cambridge, UKEvan Snyder Stem Cells and Regenerative Medicine, Burnham Institute, La Jolla, CA, USAJeff Trent The Translational Genomics Research Institute, Phoenix, AZ, USAAntonio Uccelli Neuroscience, Ophthalmology and Genetics, University of Genoa, ItalyAnnamaria Vezzani Mario Negri Institute for Pharmacological Research, Milan, ItalyAngela Vincent Neuroimmunology, University of Oxford, UKHartmut Wekerle Max Plank Institute of Neurobiology, Münich, GermanyMichael Weller Neurology, University Hospital Zürich, SwitzerlandTony Wyss­Coray Center for Tissue Regeneration, Stanford University, CA, USAFrauke Zipp Dept. of Neurology, Johannes Gutenberg University, Mainz, Germany13

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSSocial eventsMonday 5 th November 20128.15 Welcoming words5 th Nov2012Tomas Olsson – ISNI PresidentSamia J. Khoury – Conference Chair18.00 Welcome Reception at Westin Copley PlaceWednesday 7 th November 20127 th Nov201220.00 Gala Dinnerdetails will be available on the congress website www.isni2012.orgThursday 8 th November 201215.00 Closing Remarks8 th Nov201214

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSRegistrationPlease register online via the congress website www.isni2012.org12 th ESNI Course (course only)11 th ISNI Congress:ISNI MembersNon ISNI MembersStudent/Postdocs*Group rate for studentfrom same lab*UNTIL 30ᵗʰ JUNE UNTIL 30ᵗʰ SEPTEMBER ON SITE (VALID UNTIL 1ˢᵗ OCTOBER)$ 150,00$ 670,00$ 800,00$ 400,00$ 270,00$ 200,00$ 740,00$ 870,00$ 470,00$ 335,00$ 250,00$ 805,00$ 940,00$ 540,00$ 400,00Rates are in US Dollars and are tax included, payment in other currencies will not beaccepted.*Student registration form must be accompanied by a letter from the head of departmentconfirming their status and/or a valid student card. Students paying the registration forthe ISNI Conference can attend the ESNI Course free of charge. Student group rate isapplicable for a minimum of 5 participants from the same lab.From 1ˢᵗ October the online registration will be closed and you will only be able to registeron site at the congress registration desks. To speed up your on site registration, pleasedownload and fill in the registration form which will be available on the congress websitefrom 22 nd October 2012 and present it at the registration desks.Fees for participants include:• participation in scientific sessions• access to the exhibition area• printed material of the congress• name badge• certificate of attendance• welcome reception• coffee breaks• lunch coupons15

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSPaymentPayment of the registration fee must be received on or before the deadline date, otherwisethe next higher registration fee will be applied. Registrations are accepted and confirmedonly after receiving the full payment. Registrations without proof of payment will not beprocessed.ConfirmationAn official confirmation letter will be sent by e­mail after receipt of full payment. Westrongly recommend that you present your confirmation letter at the registration desksin order to collect your badge and your congress material.CancellationAny cancellation of registration must be notified in writing and will be subject to thefollowing conditions:• postmarked until 20 th August 2012 – 100% refund minus $ 50,00 handling fee• postmarked until 22ⁿᵈ October 2012 – 50% refund• no refund for cancellation received from 23 rd October and for no­showName alterationsName changes will be accepted free of charge until 22ⁿᵈ October 2012; after that date itcan be processed directly on­site. A notification of a name modification must be put inwriting and e­mailed to the Organising Secretariat.16

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSGeneral InformationDates12 th ESNI pre­congress CourseEuropean School of NeuroimmunologySunday, 4 th November 20124 th Nov201211 th ISNI CongressInternational Society of NeuroimmunologyMonday 5 th , November ­ Thursday 8 th , November 2012Congress venueThe Westin Copley Place,10 Huntington Avenue,Boston, MA, USAhttp://www.westincopleyplaceboston.com5 th ­8 thNov2012Scientific ProgrammeThe scientific programme, the most important part of the ISNI Congress, consists of magistrallectures, plenary lectures, concurrent symposia, oral platforms, poster sessions and trainingsessions.The 11 th ISNI Conference is preceeded by the 12 th ESNI Course – European School ofNeuroimmunology (www.esni.org), the official school of the ISNI.SponsorshipPharmaceutical companies, manufacturers of technical equipments and publishers of relatedscientific books, magazines and journals are invited to participate in the trade exhibition whichwill be organized at the Westin Copley Place Hotel during the conference days.The ISNI Conference offers to the companies involved in the fields of Neuroimmunology anexcellent opportunity to promote themselves to a quality audience.We expect a total of 700 to 800 delegates from all over the world.Please visit the conference website (www.isni2012.org) to download the Call for sponsorsprospectus and if interested, please contact the Organising Secretariat.17

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSCME AccreditationThe CME accreditation has been requested in the USA. Credits given can also be recognisedby authorities worldwide. Further information will be available on the congress websitewww.isni2012.orgOfficial Invitation LetterOfficial letters of invitation designed to help overcome administrative difficulties in certaincountries will be sent on request by the Organising Secretariat. It must be understood thatsuch letters do not represent a commitment on the part of the Local Organising Committeeor congress to provide any financial assistance. Participants requesting a letter of invitationmust be registered and have paid the registration fee.The registration fee is refundable should the visa application or the permission be denied.Passport and visa informationParticipants are advised to make their own arrangements and obtain the necessary legaldocuments before travelling to the USA. Those requiring to enter the USA, are stronglyadvised to submit their application in their home country.The organisers will not be able to contact or intervene with any Embassy or Consulateoffice abroad on your behalf. Please visit http://travel.state.gov/visa/ for updated info.ClimateIn the winter, the first freezing temperatures usually occur in early November.LanguageThe official language of the conference is English. No simultaneous translation will beprovided.BadgesFor organisational reasons, all participants and exhibitors are requested to wear theirbadges at all times during the conference activities. Lost badges can be replaced at theregistration desks.18

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSCertificate of attendanceCertificates of attendance will be sent to all participants by e­mail after the conference end.Lunches & breaksLunch coupons, coffee and tea breaks are included in the registration fees. Badges shouldalso be worn during these breaks. Special dietary requirements can be indicated on theregistration form.InsuranceThe organisers will not accept liability for individual medical, travel or personal insurance.It is highly recommended that all participants carry proper health and travel insurance.DisclaimerFor reasons beyond their control (such as war, strikes, acts of terrorism, earthquakes,unexpected economic events or generally by force majeure, etc.) the 11 th ISNI Congressand/or its agent EEM International Congress Services Rome (Italy) and/or its agents havethe right to immediately alter or cancel the congress or any of the arrangements,schedules, plans or other items relating directly or indirectly to the 11 th ISNI Congress.Participants shall not be entitled to any compensation for damages that result from suchalteration or cancellation. Furthermore, with the exception of any wilful damage or grossnegligence committed by the 11 th ISNI Congress and/or its agent EEM InternationalCongress Services Rome (Italy), neither the 11 th ISNI Congress not its agent EEMInternational Congress Services Rome (Italy) and/or its agents shall at any time be liablefor any direct or indirect damage suffered by the participants, including consequential andimmaterial damage, caused by failure to comply with any provision of this document.19

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSTravel InformationBy air: the Boston Logan Airport is an important hub with many destinations around theworld. When travelling to or from Boston Logan Airport, The Westin Copley Place haspartnered with one of the premiere Boston airport shuttle services, Ultimate Livery &Shuttle. Offering 24­hour pick­ups, you can book online by following the steps on thewebsite link http://www.zebrashuttle.com/hotels.htmlA taxi journey will cost you approximately $25 ­ $30 from the airport to the Westin CopleyPlace. Note that a $7.50 origination surcharge from the airport is lawful and permissible(including tolls).The T train is a service that goes from Logan airport to Boston and vice versa. For moreinformation, please copy this link into your web browser:http://www.mbta.com/riding_the_t/logan/By road: there are 3 main routes into Boston:• I­90 (Massachusetts Turnpike) from the west• I­95 from the north and south• I­93 from the north and southBy train: Amtrak has scheduled train service to Boston from New York and other points inthe Northeast Corridor. The trip from New York City takes 3 hours and a half on AcelaExpress trains, about 4 hours on other trains.Amtrak has three Boston stops:• Rte. 128 is about 12 miles from downtown and is a good place to get off if you arevisiting the western or southern suburbs.• Back Bay Station is in the Back Bay, convenient to hotels in the Back Bay and the SouthEnd and the Orange Line subway.• The other terminal is South Station, near the Financial District and on the Red Linesubway. It is convenient for the hotels along the waterfront and the theater district.Getting around BostonRead more to discover about finding your way around the city by visiting the link:http://www.cityofboston.gov/transportation/modes.aspWebsitewww.isni2012.orgThe congress website will be updated on a regular basis and will give the latest details onthe scientific programme and other information.20

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSCall for abstractsThe Congress Organising Committee invites delegates who have exciting new data availableto submit an abstract for oral or poster presentation.Participants are requested to submit an abstract via internet through the congress websiteNO LATER THAN MAY 14 th , 2012together with the registration form and fee payment, unless they have applied for a travelgrant.Please avoid submission within 24 hours of the deadline for a better performance!All abstracts will be reviewed by the Scientific Committee of the 11 th ISNI Congress who willassign the type of presentation: oral or poster. Authors will be notified the abstractacceptance/rejection and the type of presentation no later than JULY 14 th , 2012 by e­mail.Instructions for presentation will be sent to presenting authors of the accepted abstracts.Thus, presenting authors must be registered and must pay the registration fee before theearly registration deadline (AUGUST 20 th , 2012) to ensure the rights for thepresentation.All accepted abstracts will be published in a special issue of the Journal ofNeuroimmunology, provided that the Scientific Committee considers them suitable forpublication.General policyAbstracts must be original and not published or presented to any conferences prior to the11 th ISNI Congress.Abstracts may be submitted in English only via internet on the congress websitewww.isni2012.org. If you have no access to the internet or should encounter anydifficulties, please contact the Organising Secretariat at secretariat@isni2012.org.Abstracts submitted by fax or by e­mail are not acceptable.Authors are strongly advised to ensure the accuracy of the submitted abstracts. Anymistakes in literature or in scientific facts will be published as what is typed.PowerPoint computer projection will be available for oral presentations.21

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSAbstracts of Invited SpeakersInvited Speakers will have to submit their abstract via internet on the congress websiteno later than AUGUST 30 th , 2012 for publishing.Late breaking newsLate breaking news must be submitted before JUNE 15 th , 2012If data is not yet available at submission deadline, authors should present background anddesign of the study in their abstract and confirm that the results and conclusions of theirinvestigations will be ready for presentation at the 11 th ISNI Congress. Please send yourconfirmation about this in writing by e­mail or fax when submitting your abstract to theOrganising Secretariat.As in the nature of the wording, late breaking abstracts are NOT regular abstracts, butimportant contributions that cannot wait to be presented at the next ISNI congress.22

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSAbstract topicsThe Scientific Committee will review abstracts for oral or poster presentations referringto the following topics:1. B cells and antibodies2. Biomarkers3. Blood brain barrier4. Brain tumors and parneoplastic5. Clinical research6. Genetics7. Immunological mechanisms8. Infections9. Innate immune system10. Mechanisms of CNS disease11. miRNA12. Models of disease13. Neurodegeneration14. Neuroinflammation15. Omics16. Pathology17. Psychoimmunomodulation18. Stem cells19. T cells20. TherapiesMain topics• Visualizing the brain and immune system• microRNA in CNS autoimmunity• Glycans, galectins, and proteins• Inflammation in neurodegenerative diseases• Stem cells and immunity23

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSPoster instructionsAuthors are requested to be present at their posters during the session for which theirposter has been scheduled. At that time, poster chairpersons will walk around and discussposters with authors and participants.Detailed instructions for preparing posters will be available on the congress websitewww.isni2012.org24

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSTravel GrantsThe Organising Committee recognizes the importance of providing assistance to potentialyoung congress participants, to students and to delegates from low and middle­incomecountries.A limited number of travel grants will be available and will be provided in co­operationwith:ISNI – International Society of Neuroimmunologyfor ISNI Members and for members ofany National Neuroimmunology Society onlyESNI – European School of Neuroimmunologyfor students attending both ESNI pre­congress courseand ISNI CongressAINI – Italian Association of Neuroimmunologyfor AINI Members onlyOnly the presenting author of an abstract is eligible to apply for atravel grant.Deadline is the same as for abstract submission: MAY 14 th , 2012.Application can only be made by fully filling out the form available in the congress websitewww.isni2012.og page Travel Grant.25

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSParticipants applying for a travel grant must be registered stating that they have requesteda travel grant (full information will be available on the on­line registration form).If you are sponsored by a company (registration fee, hotel accommodation, travelexpenses) you are NOT entitled to apply for a travel grant.Applicants will be notified the travel grant acceptance/rejection no later than JULY 14 th ,2012 by e­mail.If you have questions, please contact the Organising Secretariat.26

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTS1­Day pre­congress ESNI Course4 th November 2012Chair:Gianvito MartinoHugh Willison9.00 am – 1.00 pm Morning Session9.00 am ­ 9.15 am Registration9.15 am – 9.30 am Introduction to the course9.30 am ­ 10.15 am Richard RansohoffLymphocyte trafficking in the CNS10.15 am ­ 11.00 am David HaflerThe role of immune genes in the CNS11.00 am ­ 11.30 am Coffee Break11.30 am ­ 12.15 pm Ari WaismanImmune regulation in CNS autoimmunity12.15 pm ­ 1.00 pm Carla ShatzInflammation and synaptic plasticity1.00 pm ­ 2.30 pm Lunch with the expert2.30 pm­6.00 pm Afternoon session2.30 pm ­ 3.15 pm David BakerAnimal models of neuroinflammation3.15 pm ­ 4.00 pm Dorian McGavernBrain imaging in infection4.00 pm ­ 4.30 pm Tea Break4.30 pm ­ 5.15 pm Daniel H. GeschwindThe role of immunity in psychiatric disorders5.15 pm ­ 6.00 pm Michal SchwartzImmunity and brain plasticity in neurodegeneration27

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTS11 th ISNI Congress ­ Day 15 th November 2012Morning Session8:15 am Main Hall: Welcome AddressesTomas Olsson – ISNI PresidentSamia J. Khoury, MD – Conference Chair8:30 am Main Hall: Plenary Symposium 1Visualizing the brain and immune system8:30 am Jeff LichtmanMolecular and Cellular Biology, Harvard Medical School,Boston, MA, USAComputational talk/genetics9:15 am Jeff TrentTGen the translational genomics research institute, Phoenix, AZ, USA10:00­10:30 am Coffee Break10:30 am – 12:00 pm Concurrent SymposiaRoom AIntravital two­photon imaging in the CNSAlexander FlügelNeuroimmunology, Institute for Multiple Sclerosis Research,Göttingen , GermanyMartin KerschensteinerInstitute of Clinical Neuroimmunology, Ludwig­MaximiliansUniversity Münich, GermanyRoom BRoom CB­cells in neuroimmune diseaseStephen HauserNeurology Dept, UCSF, San Francisco, CA, USAAmit Bar­OrNeurology and Neurosurgery, McGill University, CanadaGenotype/PhenotypeStephen SawcerDepartment of Clinical Neuroscience, University of Cambridge, UKPhilip L. DeJagerBrigham and Women’s Hospital, Boston, MA, USA28

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSAfternoon Session12:00­1:30 pm Lunch Break & Poster Session1:30 pm Main Hall: Plenary Lecture 1The Dale McFarlin LectureAlastair CompstonClinical Neurosciences, University of Cambridge, UK2:30­4:00 pm Oral Platforms4:00­5:00 pm Poster Session5:00­6:00 pm Training Sessions 1Nir HacohenHarvard Medical School, Massachusetts General Hospital, Boston,MA, USA6:00­7:30 pm Welcome Reception29

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTS11 th ISNI Congress ­ Day 26 th November 2012Morning Session8:30 am Main Hall: Plenary Symposium 2miRNA in neuroimmune diseases8:30 am Robert DarnellInvestigator, Rockefeller University, New York, NY, USAOverview of immune regulation in CNS9:15 am Alexander RudenskyMemorial Sloan­Kettering Cancer Center, New York, NY, USA10:00­10:30 am Coffee Break10:30 am – 12:00 pm Concurrent SymposiaRoom ARoom BRoom CNeuroimmunology of brain tumorsMichael WellerDepartment of Neurology, University Hospital Zürich, Germany“Targeting transforming growth factor­β in glioblastoma”Michael PlattenDepartment of Neurooncology, University of Heidelberg MedicalSchool, Germany“The aryl hydrocarbon receptor in tumor immunity:lessons from malignant glioma”Linda LiauNeurosurgery, David Geffen School of Medicine at UCLA,Los Angeles, CA, USA“Dendritic cell­based immunotherapy for glioma”Inflammation in neurodegenerative disordersZaal KokaiaLund Stem Cell Center University Hospital, SwedenAnnamaria VezzaniMario Negri Institute for Pharmacological Research, Milan, ItalyRegulatory T cells in neuroimmune diseasesDavid HaflerNeurology and Immunobiology, Yale University, New Haven, CT, USARoberto FurlanNeuroimmunology Unit, San Raffaele Scientific Institute,Milan, Italy and Women’s Hospital, Boston, MA, USA30

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSAfternoon Session12:00­1:30 pm Lunch Break & Poster Session1:30 pm Main Hall: Plenary Lecture 2The Newson­Davis LectureVanda A LennonImmunology and Neurology, Mayo Clinic, Rochester, MN, USA2:30­4:00 pm Oral Platforms4:00­5:00 pm Poster Session5:00­6:00 pm Training Sessions 2Christopher LoveDepartment of Chemical Engineering, MIT, Cambridge, MA, USA31

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTS11 th ISNI Congress ­ Day 37 th November 2012Morning Session8:30 am Main Hall: Plenary Symposium 3Protein­Glycan interactions in neuroimmune diseases8:30 am Gabriel RabinovichInstitute of Biology & Experimental Medicine, Universityof Buenos Aires, ArgentinaMicrobiome9:15 am W. Ian LipkinNeurology and Pathology, Mailman School of Public Health andCollege of Physicians and Surgeons, Columbia University, NY, USA10:00­10:30 am Coffee Break10:30 am – 12:00 pm Concurrent SymposiaRoom AThe microbiomeLLoyd KasperNeurology, Microbiology and Immunology Dartmouth,Hanover, NH, USAHartmut WekerleMax Plank Institute of Neurobiology, Münich, GermanyRoom BWhat makes T cells encephalitogenicBurkhard BecherInstitute of Experimental Immunology, University of Zürich,SwitzerlandVijay KuchrooNeurology, Harvard Medical School, Boston, MA, USARoom CInnate immunity in neuroinflammationand brain developmentFrauke ZippDepartment of Neurology, Johannes Gutenberg University,Mainz, GermanySerge RivestMolecular Endocrinology, Laval University, Québec, Canada32

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSAfternoon Session12:00­1:30 pm Lunch Break & Poster Session1:30 pm Main Hall: Plenary Lecture 3The Immunology LectureKingston MillsImmunology Research Centre, Trinity College, Dublin, Ireland2:30­4:00 pm Oral Platforms4:00­5:00 pm Poster Session5:00­6:00 pm Training Sessions 3Hidde PloeghBiology, Whitehead Institute, MIT, Cambridge, MA, USA33

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTS11 th ISNI Congress ­ Day 48 th November 2012Morning Session8:30 am Main Hall: Plenary Symposium 4Stem cells in immunity and Disease8:30 am Gianvito MartinoDivision of Neuroscience, San Raffaele Hospital, Milan, ItalyCan transplanted stem cells cause cancer9:15 am Evan SnyderStem Cells and Regenerative Medicine Burnham Institutefor Medical Research, La Jolla, CA, USA10:00­10:30 am Coffee Break10:30 am – 12:00 pm Concurrent SymposiaRoom AStem cells and immunityJonathan KipnisUniversity of Virginia School of Medicine, Charlottesville, VA, USA“Phagocytic activity of neuronal progenitors and adult neurogenesis”Stefano PluchinoCambridge Centre for Brain Repair and Stem Cell Initiative,University of Cambridge, UK“Horizontal cell­to­cell communication programs and immuneregulatory neural stem cell therapies”.Tony Wyss­CorayCenter for Tissue Regeneration, Repair, and Restoration,Stanford University, CA, USA,“Rejuvenation of the aged systemic milieu supportsadult hippocampal neurogenesis”D. KarussisHadassah Medical Organization, Jerusalem, Israel“The in vivo and in vitro immunological effects of MSCin MS patients”Room BParaneoplastic and Non­paraneoplastic diseasesAngela VincentNeuroimmunology, University of Oxford, UKJosep DalmauNeurology, University of Pennsylvania, Philadelphia, PA, USA34

PRELIMINARY SCIENTIFIC PROGRAMME & CALL FOR ABSTRACTSRoom CMorning SessionProgress in MS therapeuticsLudwig KapposNeurology, University Hospital, Basel, SwitzerlandHans­Peter HartungClinic Neurology,, Heinrich­Heine University, Düsseldorf, GermanyAfternoon Session12:00­2:00 pm Lunch Break & Poster Session2:00 pm Main Hall: Plenary Lecture 4The Neurobiology LectureDouglas FieldsNervous System Development and Plasticity Section, NationalInstitute of Child Health and Human Development3:00 pm Closing Remarks35