CG123 Common mental health disorders - National Institute for ...

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Methods used to develop this guideline● MEDLINE/MEDLINE In-Process● Psychological Information Database (PsycINFO).The search strategies were initially developed for MEDLINE before being translatedfor use in other databases/interfaces. Strategies were built up from a number oftrial searches, and from discussions of the results of the searches with the reviewteam/GDG, to ensure that all possible relevant search terms were covered.Reference ManagerCitations from each search were downloaded into Reference Manager (a softwareproduct for managing references and formatting bibliographies) and duplicatesremoved. Records were then screened against the inclusion criteria of the reviewsbefore being quality appraised (see below). The unfiltered search results were savedand retained for future potential re-analysis to help keep the process both replicableand transparent.Search filtersTo aid retrieval of relevant and sound studies, filters were used to limit the searchesto systematic reviews, RCTs and observational studies. The systematic review andRCT filters are adaptations of designs constructed by the NHS Centre for Reviewsand Dissemination and the Health Information Research Unit of McMasterUniversity, Ontario. The observational studies filter was developed in-house. Eachfilter comprises index terms relating to the study type(s) and associated text words forthe methodological description of the design(s).Date and language restrictionsSystematic database searches were initially conducted in December 2009. The searchfor systematic reviews was restricted to the last 10 years because older reviews wereconsidered to be less useful. Search updates were generated on a 6-monthly basis,with the final re-runs carried out in September 2010 ahead of the guideline consultation.After this point, studies were only included if they were judged to be exceptionalby the GDG (for example, if the evidence was likely to change a recommendation).Although no language restrictions were applied at the searching stage, foreignlanguage papers were not requested or reviewed unless they were of particular importanceto a clinical question. Date restrictions were applied for searches for systematicreviews and for updates of published reviews only (see Appendix 5). No date restrictionswere imposed for the remainder of the searches.Post-guideline searchingFollowing the draft guideline consultation, a search for systematic reviews on ‘predictorsof response’ was undertaken for the period from 2003 up to January 2011.Other search methodsOther search methods involved: (1) scanning the reference lists of all eligible publications(systematic reviews, stakeholder evidence and included studies) for morepublished reports and citations of unpublished research; (2) checking the tables of47
Methods used to develop this guidelinecontents of key journals for studies that might have been missed by the database andreference list searches; (3) tracking key papers in the Science Citation Index (prospectively)over time for further useful references.Full details of the MEDLINE search strategies/filters used for the systematicreview of clinical evidence are provided in Appendix 6.Study selection and quality assessmentAll studies included after the first scan of citations were acquired in full andre-evaluated for eligibility at the time they were being entered into Review Manager5 (Cochrane Collaboration, 2008) or evidence tables. More specific eligibility criteriawere developed for each review question and are described in the relevant clinicalevidence chapters. Eligible systematic reviews and primary-level studies were criticallyappraised for methodological quality (see Appendix 7 for methodology checklists).The eligibility of each study was confirmed by at least one member of theappropriate topic group.For some review questions, it was necessary to prioritise the evidence with respectto the UK context (that is, external validity). To make this process explicit, the GDGtook into account the following factors when assessing the evidence:● participant factors (for example, gender, age and ethnicity)●●provider factors (for example, model fidelity, the conditions under which the interventionwas performed and the availability of experienced staff to undertake theprocedure)cultural factors (for example, differences in standard care and differences in thewelfare system).It was the responsibility of each topic group to decide which prioritisation factorswere relevant to each review question in light of the UK context and then decide howthey should modify their recommendations.Unpublished evidenceThe GDG used a number of criteria when deciding whether or not to accept unpublisheddata. First, the evidence must have been accompanied by a trial report containingsufficient detail to properly assess the quality of the data. Second, the evidencemust have been submitted with the understanding that data from the study and asummary of the study’s characteristics would be published in the full guideline.Therefore, the GDG did not accept evidence submitted as commercial in confidence.However, the GDG recognised that unpublished evidence submitted by investigatorsmight later be retracted by those investigators if the inclusion of such data wouldjeopardise publication of their research.3.5.3 Data extractionStudy characteristics and outcome data were extracted from all eligible studies, whichmet the minimum quality criteria, using Review Manager 5 (Cochrane Collaboration,2008) or Microsoft Word-based evidence tables (Microsoft, 2007).48
Page 1 and 2: Commonmental healthdisordersTHE NIC
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Summary of recommendations8.1.1.6 S
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Summary of recommendationsFigure 12
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Summary of recommendations●Genera
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Summary of recommendations8.4 STEPS
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Summary of recommendations●●a g
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Summary of recommendationsDiscuss w
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Summary of recommendationsinclude p
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Appendices9 APPENDICESAppendix 1: S
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Appendix 1of a depressive disorder
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Appendix 1b) Assessment of anxiety
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Appendix 2APPENDIX 2:DECLARATIONS O
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Appendix 2Mr Mike BessantEmployment
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Appendix 2Personal non-pecuniary in
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Appendix 2Actions takenMr Rupert Su
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Appendix 2Personal family interestN
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Appendix 3APPENDIX 3:STAKEHOLDERS A
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Appendix 4ClinicalpopulationPeople
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Appendix 4Case identificationNo. Pr
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Appendix 5APPENDIX 5:REVIEW PROTOCO
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Appendix 7APPENDIX 7:METHODOLOGY CH
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Appendix 9APPENDIX 9:METHODOLOGY CH
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Appendix 92.10 Are all important pa
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Appendix 9case also excludes costs
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Appendix 9For consistency, the EQ-5
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Appendix 9Answer ‘yes’ if the a
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Appendix 9Answer ‘yes’ if the e
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Appendix 9Answer ‘yes’ if appro
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Appendix 10APPENDIX 10: EVIDENCE TA
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Appendix 11APPENDIX 11:HIGH PRIORIT
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Appendix 11discussion of options bu
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Appendix 13APPENDIX 13:GENERALIZED
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ReferencesAndlin-Sobocki, P., Jöns
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ReferencesBower, P., Gilbody, S., R
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ReferencesCooper, S., Smiley, E., M
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ReferencesEhlers A., Gene-Cos N. &
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ReferencesGiles, D. E., Jarrett, R.
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ReferencesHorowitz, M. J., Wilner,
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ReferencesKnapp, M. & Ilson, S. (20
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ReferencesMarks, J., Goldberg, D. P
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ReferencesNCCMH (forthcoming) Self-
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ReferencesOzer, E. J., Best, S. R.,
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ReferencesSartorius, N. (2002) Eine
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ReferencesTiemens, B. G., Ormel, J.
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ReferencesWilkinson, M. J. B. & Bar
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Glossarybeliefs and interpretations
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Glossaryto learn to become more awa
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Abbreviations12 ABBREVIATIONSADDADS
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AbbreviationsOASISOCDONSORPHQ (-A,
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