Neuroendocrine Tumors of the Pancreas

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Layout• Intoduction• Look alikes• Two of a kind– UICC/AJCC versus ENETS TNM• Is there more ?– Molecular PathologyProf. Dr. med. P. KomminothZürich, Switzerland
Page 1: Neuroendocrine Tumors of thePancrea
Page 5 and 6: GlucagonomapostopProf. Dr. med. P.
Page 7 and 8: What do the clinicians want from us
Page 9 and 10: is it .....or is it not ?Prof. Dr.
Page 11 and 12: DD solid pancreatic tumor• Pancre
Page 13 and 14: Prof. Dr. med. P. KomminothZürich,
Page 21 and 22: Acinar cell carcinomaProf. Dr. med.
Page 29 and 30: Metastatic SPN4/95 (5%)Prof. Dr. me
Page 45 and 46: ENETS GradingProf. Dr. med. P. Komm
Page 53 and 54:
1072 patients8 European cancer cent
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Prof. Dr. med. P. KomminothZürich,
Page 57 and 58:
Molecular pathology of PanNENand po
Page 59 and 60:
MEN1 in sporadic PanNENMutationsAll
Page 61 and 62:
Sporadic PET: progression model4+,
Page 63 and 64:
Page 65 and 66:
43%17%Prof. Dr. med. P. KomminothZ
Page 67 and 68:
DAXX ATRX-> DAXX ATRX probably late
Page 69 and 70:
Sporadic PanNEN: Progression modelN
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Page 73 and 74:
ThanksProf. Dr. med. P. KomminothZ
Page 75 and 76:
PanNEN: outcome• CK-19 +• COX-2
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Neuroendocrine Tumors of the Pancreas

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