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SkanIt Software

SkanIt 06_0203006.indd - AB Ninolab

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<strong>SkanIt</strong> ®<strong>Software</strong>Reader control and data handlingsoftware for optimized flexibilityand ease of use


Powerful software for effortless resultsThermo Electron Corporation’s <strong>SkanIt</strong> <strong>Software</strong> is the ultimate tool for both microplatereader control and data handling. There are two editions of <strong>SkanIt</strong> <strong>Software</strong> available:a Research Edition for scientists working in life science research, and a Drug DiscoveryEdition offering features needed for compliance with the FDA’s 21 CFR Part 11, for the drugdiscovery industry.The measurement can be followed inreal-time on the screen.Kinetic or spectral scanning curvesfrom different samples can be combinedfor data comparison.Assay setup andinstrument control<strong>SkanIt</strong> <strong>Software</strong> gives the user totalcontrol over the Varioskan ® , Appliskanand Multiskan ® Spectruminstruments, and supports optimaluse of the instrument’s features.<strong>SkanIt</strong> <strong>Software</strong> is highly visual andhas a familiar Windows-type userinterface that makes assay setupand data handling easy.Visual workflow withthe steplist featureThe workflow is visual and easy tofollow with the graphical steplistfeature. Any assay can easily becreated by adding steps to thesteplist. Each step corresponds toan instrument action (e.g. measure,dispense, incubate) and the order ofthe steps in the steplist describesthe order in which the instrumentis going to perform the desiredactions. A new action can easilybe defined by adding a step to thedesired position in the steplist. Astep is added simply by clicking thestep-shortcut button or by selectingthe appropriate step from theSteps menu. For simplicity, only theparameters of the selected step arevisible.Maximum flexibilityfor complex assaysThe steplist also offers utmostflexibility in assay setup, as anynumber of steps can be addedto the steplist. A session cancontain several measurementsteps thus allowing the use ofdifferent measurement types,and even different technologies,in one session. The measurementtechnologies supporteddepend on the instrument in useand can include photometric, FP(fluorescence polarization) andTRF (time-resolved fluorescence)measurements. For multilabelassays, several wavelengths canbe measured almost simultaneouslywith all measurement types,and simultaneous dispensing andmeasurement enables assays likeCa 2+ assays and fast kinetic reactionsto be followed directly fromreaction onset.Real-time data duringmeasurementThe Execution Progress windowlets the user follow measurementsin real-time on the screen. Forendpoint measurements in 96- and384-well plates, the measured datais shown for each well as it is measured.For kinetic and spectral scanningmeasurements, the curves canalso be followed in real-time duringthe progress of the measurement.Effortless data reduction withbuilt-in calculations<strong>SkanIt</strong> <strong>Software</strong> makes data reductionand calculations effortless. TheResults steplist works in the sameThe session tree structure and the steplist makeassay setup easy and the workflow logical.intuitive way as in the assay setupsection, and gives you control overa comprehensive set of built-in calculations.These calculations includeBlank Subtraction; Multipointreduction; Curve Fit with 8 differentfit types including 1 to 4 degreepolynomials, cubic spline and fourparameter logistics; Cut-Off with upto 5 user defined limits; EffectiveDose; Kinetic Processors for reductionof kinetic data; Ratio/Inhibition;Spectral Reduction for spectralscanning data calculations andQuality Control (QC). Additionally,the User Equation calculator, whichworks just like a pocket calculator,can be used for easy creation ofcustom-made calculations.Comprehensive reportsand easy export of dataBoth measurement results andcalculated data can be displayed intable and list format for easy interpretationand analysis. For kineticand spectral scanning data graphsare displayed, and graphs fromdifferent wells can easily be combined.Data can be exported eithermanually or automatically in .pdf,.txt and .xls format for use in othersystems such as Microsoft ® Excel.Alternatively, extensive reports canbe created using the Report generator.In the Drug Discovery Edition,such reports can be electronicallysigned.Data reduction iseasily set up byadding calculationsteps to theResults steplist.The familiar pocketcalculator screenis used for easysetup of QC, Cut-Off and User Equationcalculations.Integration withautomated systems<strong>SkanIt</strong> <strong>Software</strong> offers a specialremote control interface for integrationwith LIMS and automatedsystems. The remote interface hasbeen implemented as a generic,automation system independent,ActiveX ® dll component, whichallows easy integration with differentrobotic systems.


Features needed for21 CFR Part 11 compliance<strong>SkanIt</strong> <strong>Software</strong> has been designedtaking the requirements of 21 CFRPart 11 into account. It is basedon a database and all sessions andmeasurement data are saved in thedatabase, thereby ensuring optimaldata integrity and easy backup ofdata.<strong>SkanIt</strong> <strong>Software</strong> supports the useof separate User Groups that havedifferent access to the softwarefeatures. There are predefinedUser Groups, but additional groupscan be added and the rights of theexisting groups can be modified.Logon to <strong>SkanIt</strong> <strong>Software</strong> requires aunique combination of a user nameand a password thereby limitingsystem access to authorized usersonly. No two users can have thesame user name and the passwordmust be changed on a regular basisas defined by the system administrator.All actions regarding user management(changing or adding UserGroups, adding new users to thedatabase, changing the rightsof users etc.) are automaticallyrecorded in a time-stamped AuditTrail. Additionally, all actions regardingthe creation of new sessions,changes to existing sessions,execution of sessions etc. are alsoautomatically recorded in the AuditTrail. The Audit Trail makes it possibleto easily identify “Who didWhat and When?” at a later stage.<strong>SkanIt</strong> <strong>Software</strong> also supports theuse of an Electronic Signature in theform of a true Digital Signature withdata encryption for ultimate datasecurity.<strong>Software</strong> editions with ordering information5187010 <strong>SkanIt</strong> <strong>Software</strong> for Varioskan, Research Edition5187020 <strong>SkanIt</strong> <strong>Software</strong> for Varioskan, Drug Discovery Edition5187030 <strong>SkanIt</strong> <strong>Software</strong> for Multiskan Spectrum, Research Edition5187060 <strong>SkanIt</strong> <strong>Software</strong> for Multiskan Spectrum, Drug Discovery Edition5187050 <strong>SkanIt</strong> <strong>Software</strong> for Appliskan, Research EditionHW and SW specificationsPC requirementsInterfaceSerial communication via an RS-232 full duplex interface (and USB with Varioskan)Supported operating systems – Microsoft Windows ® 2000 with Service Pack 4– Microsoft Windows XP Professional with Service Pack 1 (or greater)Disk space≥ 2.5 GB free disk spaceProcessor≥ Intel Pentium ® III 800 MHz recommendedMemory≥ 512 MB RAMSerial ports available 1Pointing deviceMouse or equivalent is necessaryCD-ROM drive 1Monitor / color settings SVGA monitor with at least 1024 x 768 resolution and at least a 16-bit color environmentBrowserMicrosoft Internet Explorer 6.0 (or greater) installed© Thermo Electron Corporation. All rights reserved. Thermo Electron Corporation and Analyze. Detect. Measure.Control are trademarks of Thermo Electron Corporation. All product and brand names are registered trademarks of their respective owners.North America: +1 866 984 3766Europe: Austria +43 1 801 40 0, Belgium +32 2 482 30 30,Finland +358 9 329 100, France +33 2 28 03 20 00 or +33 1 6918 7777,Germany +49 6184 90 6940 or +49 6103 408 1012, Italy +39 02 95059 1,Netherlands +31 76 571 4440, Russia/CIS +7 095 225 11 15,Spain/Portugal +34 93 223 3154, Switzerland +41 1 454 12 12,UK/Ireland +44 870 609 9203Asia: India +91 22 5542 9494, Japan +81 45 453 9220,China +86 21 6865 4588 or +86 10 5850 3588,Other Asian countries +852 2885 4613Countries not listed: +49 6184 90 6940 or +33 2 28 03 20 001516260-2 Thermo Electron Corporation/imageneering | worldwide partners/Suomen Painotuote 02/06 BRO-MIB-<strong>SkanIt</strong>-0306-02www.thermo.com/mpi

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