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120 SUNDAY • MAY 15<br />
102 Toll-Like Receptor Signaling in Human Lung Pericytes/J.P.<br />
Higuero, C.L. Wilson, L.M. Felton, S.E. Stephenson, C.F. Hung, W.A.<br />
Altemeier, J.E. Baatz, L.M. Schnapp, Charleston, SC, p.A2641<br />
103 The RIG-I-Like Receptor Pathway Is Protective During Sterile<br />
Acute Lung Injury/M.P. Mohning, A.L. McCubbrey, K.J. Mould,<br />
P.M. Henson, W. Janssen, Aurora, CO, p.A2642<br />
104 Toll-Like Receptor 5 Modulates MyD88-Dependent Toll-Like<br />
Receptor 4 Signaling/C.G. Johnson, J. Sciurba, A. Rice, J. Aloor,<br />
J. Cyphert, K. Bulek, X. Li, M.B. Fessler, S. Garantziotis, Research<br />
Triangle Park, NC, p.A2643<br />
105 ApoA-I Binding Protein Attenuates Murine ARDS/B.T. Suratt, E.<br />
Burg, N. Ubags, S.-H. Choi, L. Fang, Y. Miller, Burlington, VT,<br />
p.A2644<br />
106 Overexpression of Decay Accelerating Factor Mitigates<br />
Fibrotic Responses to Lung Injury/R. Vittal, A.J. Fisher, E.L.<br />
Thompson, E.A. Mickler, M.R. Vasko, D.S. Wilkes, H. Gu, Ann<br />
Arbor, MI, p.A2645<br />
107 Modulation of TLR3-Stimulated Release of IL-26 by IL-17A and<br />
IL-22 in Bronchial Epithelial Cells/K.F. Che, L. Palmberg, A.<br />
Linden, Stockholm, Sweden, p.A2646<br />
108 Plasminogen Activator Inhibitor-1 (PAI-1) Plays a Critical Role<br />
in Alcohol-Enhanced Acute Lung Injury/L. Poole, V. Massey, E.<br />
Torres-Gonzalez, D. Siow, N. Warner, J. Luyendyk, J.D.<br />
Ritzenthaler, J. Roman, G. Arteel, Louisville, KY, p.A2647<br />
109 Transient Receptor Potential Vanilloid Antagonism Alleviates<br />
the Propagation of Lung Injury/M. Cereda, Y. Xin, S. Kadlecek, J.<br />
Zeng, A. Rodriguez, H. Staroba, N. Meeder, Q. Bey, H. Profka, S.<br />
Siddiqui, M. Pourfathi, H. Hamedani, R.R. Rizi, Philadelphia, PA,<br />
p.A2648<br />
110 Targeting Glutamine Metabolism as a Novel Means to Prevent<br />
LPS-Induced Acute Lung Injury/C.L. Vigeland, Y. Chan-Li, S.L.<br />
Collins, A.H. Hughes, M.-H. Oh, J.D. Powell, M.R. Horton,<br />
Baltimore, MD, p.A2649<br />
111 Orchestrating Role of Apoptosis Inhibitor of Macrophage (AIM)<br />
in Resolution of Acute Lung Injury in Mice/H. Kimura, M. Suzuki,<br />
S. Konno, T. Miyazaki, H. Shindou, M. Nishimura, Sapporo, Japan,<br />
p.A2650<br />
112 Uncoupled Inducible Nitric Oxide Synthase Influences<br />
Macrophage Polarization in Acute Lung Injury/T. Golden, M.<br />
Crabtree, K. Channon, A.J. Gow, Piscataway, NJ, p.A2651<br />
113 1,5-Anhydro-D-Fructose, a Monosaccharide from<br />
Glycogen/Starch, Ameliorates Bleomycin-Induced Lung Injury<br />
by Inhibiting Inflammasome Activation/S. Noma, T. Saitoh, K.-I.<br />
Kawahara, Y. Ito, H. Inoue, I. Maruyama, Kamogawa City, Japan,<br />
p.A2652<br />
114 Deficiency of a7 Nicotinic Acetylcholine Receptor Lessens<br />
Bleomycin-Induced Lung Injury and Fibrosis/X. Su, P. Sun, M.<br />
Pan, C. Zhao, L. Li, Shanghai, China, p.A2653<br />
115 Heme Oxygenase-1 Regulates ROS-ERK1/2 Signaling in<br />
Silica-Induced Lung Injury/K. Nakashima, T. Sato, Y. Shibata, R.<br />
Ushio, M. Ikeda, H. Watanabe, K. Nagai, K. Tashiro, H. Nagakura,<br />
N. Horita, M. Yamamoto, M. Shinkai, M. Kudo, T. Kaneko,<br />
Yokohama, Japan, p.A2654<br />
116 Immune Exhaustion and IL-6/STAT3 Activation in IPF<br />
Lymphocytes/A. Young, G. Shaginurova, J.A. Kropski, T.S.<br />
Blackwell, W. Drake, Nashville, TN, p.A2655<br />
117 The EC-SOD R213G Polymorphism Enhances Recovery of<br />
Bleomycin-Induced Airway Inflammation Mitigating<br />
Subsequent Fibrosis and Pulmonary Hypertension/G.C.<br />
Mouradian, R. Gaurav, J. Maltzahn, J. Varasteh, B.C. Hartman,<br />
R.P. Bowler, E. Grayck, Aurora, CO, p.A2656<br />
118 Circulating Fibrocytes as Biomarkers of Outcome in Acute<br />
Respiratory Distress Syndrome/A. Alrbiaan, M. Burdick, A. Kadl,<br />
K.B. Enfield, B. Mehrad, Charlottesville, VA, p.A2657<br />
119 In Immature Mice, Hyperoxia-Activated CLEC9A+, CD103+<br />
Dendritic Cells Are Sufficient to Confer Exaggerated T Cell<br />
Activation and Type 1 Inflammation/T. Cui, B. Maheshwer, A.P.<br />
Popova, Ann Arbor, MI, p.A2658<br />
120 A Genome-Wide Association Study Identifies Genetic Variation<br />
in MBP that Is Associated with Ventilator-Free Days in Patients<br />
with ARDS in the iSPAAR Consortium/I. Barnett, C.S. Calfee, M.<br />
Matthay, N.J. Meyer, C. Mikacenic, G. O’Keefe, H. Hakonarson,<br />
A.J. Sandford, M. Obeidat, D.S. Postma, D.C. Nickle, Y. Bosse,<br />
G.P. Jarvik, K. Walley, J. Russell, X. Lin, D.C. Christiani, M.M.<br />
Wurfel, Boston, MA, p.A2659<br />
121 Airway Inflammation at Birth and Lung Function at School Age<br />
in Preterm Neonates: A Pilot Study/M. Slaats, M. Al-Nejar, N.<br />
Everaars, E. Wouters, L. Mahieu, E. Oostveen, J. De Dooy, W. De<br />
Backer, S. Verhulst, Edegem, Belgium, p.A2660<br />
122 Regulation of Pseudomonas Aeruginosa Exoprotease and<br />
Elastase Activity by Thrombospondin-1/J. Zupetic, Y. Qu, T.F.<br />
Olonisakin, M. Hulver, Z. Xiong, J. Bomberger, P. Thibodeau, P.<br />
Ray, J.S. Lee, Pittsburgh, PA, p.A2661<br />
123 Circulating Thrombogenic Endothelial Cell-Derived<br />
Microparticles Are Present in Patients with Systemic<br />
Sclerosis/M.J. Scott, S. Osher, M. Hinchcliff, J.E. Dematte, I.<br />
Weiss, M. Cuttica, L. Morales-Nebreda, J. Varga, D. Vaughan, H.C.<br />
Kwaan, G.S. Budinger, G.M. Mutlu, Chicago, IL, p.A2662<br />
124 G-CSF and IL-6 Are Required for Early Post Burn Neutrophilia<br />
and Increased Lung Myeloperoxidase Activity/J.C. Gardner,<br />
J.G. Noel, L. Pitstick, N.M. Nikolaidis, F.X. McCormack, Cincinnati,<br />
OH, p.A2663<br />
125 Genome-Wide Expression Profiling of Acute Respiratory<br />
Distress Syndrome (ARDS)/P. Tejera, R. Zhang, Y. Wei, Z. Zhu,<br />
Z. Wang, L. Su, D.C. Christiani, Boston, MA, p.A2664<br />
A102<br />
POSTER DISCUSSION SESSION<br />
HIGHLIGHTS IN PATIENT-CENTERED RESEARCH:<br />
METHODS AND OUTCOMES<br />
2:15 p.m. - 4:15 p.m. MOSCONE CENTER<br />
Room 309 (South Building, Esplanade Level)<br />
Poster Viewing 2:15-3:00<br />
Discussion 3:00-4:15<br />
ATS 2016 • San Francisco