Final Program
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TUESDAY • MAY 17 291<br />
P1412<br />
P1413<br />
P1414<br />
C64<br />
Chronic Endurance Exercise Attenuates Impairments in<br />
VO2max in Rats with Pulmonary Arterial Hypertension/D.<br />
McCullough, A. Vang, S. Heo, G. Choudhary, Auburn, AL, p.A5662<br />
Dynamic Fluctuations of Circulating Growth Hormone in<br />
Patients with Chronic Lung Disease/S. Sahni, A. Iftikhar, S.<br />
Verma, Y.-M. Yang, A. Talwar, P.B. Sehgal, E.J. Miller, New Hyde<br />
Park, NY, p.A5663<br />
Pyridostigmine for Exercise Intolerance Treatment in Preload<br />
Failure/R.K. Oliveira, J.A. Tracy, A.L. Karin, A. Waxman, D.<br />
Systrom, Sao Paulo, Brazil, p.A5664<br />
THEMATIC POSTER SESSION<br />
ALI AND BARRIER FUNCTION<br />
9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />
Viewing: Posters will be on display for entire session.<br />
Area M, Hall D (North Building, Lower Level)<br />
Discussion: 11:00-11:45: authors will be present for individual discussion<br />
11:45-12:45: authors will be present for discussion with assigned facilitators<br />
Facilitator:<br />
P1416<br />
P1417<br />
P1418<br />
P1419<br />
P1420<br />
P1421<br />
P1422<br />
B.J. McVerry, MD, Pittsburgh, PA<br />
Spleen Tyrosine Kinase Signaling Mediates Endothelial Barrier<br />
Disruption in Acute Lung Injury/S. Slavin, V. Grose, A. Leonard,<br />
A. Pietropaoli, F. Fazal, A. Rahman, Rochester, NY, p.A5665<br />
Lung Ischemia-Reperfusion Injury and Endothelial<br />
ROS-Induced Ca2+ Influx Are Attenuated by Loss of CD36, a<br />
Fatty Acid Transporter/K. Suresh, L. Servinsky, O. Rentsendorj,<br />
J. Dodd-o, D.B. Pearse, L. Shimoda, Baltimore, MD, p.A5666<br />
The S1P Transporter, Spns2, Regulates HGF/C-Met-Mediated<br />
Lamellipodia Formation and Migration of Human Lung<br />
Endothelial Cells/P. Fu, P.V. Usatyuk, D.L. Ebenezer, V.<br />
Natarajan, Chicago, IL, p.A5667<br />
Inhibition of Xanthine Oxidoreductase with Febuxostat<br />
Promotes Lung Injury Resolution in a Murine Model of<br />
Endotoxemia/L. Johnston, M. Damarla, K. Carino, M. Aladdin, L.<br />
Varela, L. Wang, T. Kolb, B.S. Kim, R.L. Damico, N.R. Aggarwal,<br />
P.M. Hassoun, Baltimore, MD, p.A5668<br />
Hsp90 Inhibitors Prevent NF-kB-Dependent Gene Activation in<br />
Human Lung Microvascular Endothelial Cells by Inducing<br />
MDM2-Dependent Sirt-2-Promoter Binding/G.S. Thangjam, B.<br />
Charalampos, B. Nektarios, B.W. Gregory, M.A. Clements, J.<br />
Newton, J.D. Catravas, Norfolk, VA, p.A5669<br />
Equilibrative Nucleoside Transporter 1 Mediates<br />
Adenosine-Induced Endothelial Mitochondrial Dysfunction and<br />
Contributes to Cigarette Smoke Priming for Acute Lung<br />
Injury/E. Chambers, J. Ko, S.I.S. Rounds, Q. Lu, M.R. Blackburn,<br />
Providence, RI, p.A5670<br />
Circulatory Microparticles and Lung Endothelial Cell Function<br />
in Acute Respiratory Distress Syndrome Patients/T. Shah, C.<br />
Bardita, N. Jeganathan, R. Balk, D. Predescu, S.A. Predescu,<br />
Chicago, IL, p.A5671<br />
Facilitator:<br />
P1423<br />
P1424<br />
P1425<br />
P1426<br />
P1427<br />
P1428<br />
P1429<br />
Facilitator:<br />
P1430<br />
P1431<br />
P1432<br />
P1433<br />
P1434<br />
P1435<br />
M. Damarla, MD, Baltimore, MD<br />
The Functional Impact of Pulmonary Endothelial Glycocalyx<br />
Remodeling After Sepsis/T.C. Lane, J.F. Colbert, Y. Yang, S.M.<br />
Haeger, J.A. Ford, K.L. Dailey, E.P. Schmidt, Aurora, CO, p.A5672<br />
Glycocalyx Degradation Differs Between Direct and Indirect<br />
Lung Injury/A.M. DeDent, S.M. Haeger, M.J. Perez, Y. Yang, J.A.<br />
Ford, K.L. Dailey, F. Zhang, R.J. Linhardt, E.P. Schmidt, Aurora,<br />
CO, p.A5673<br />
Dyslipidemia Is Associated with Increased Markers of<br />
Endothelial Activation Following Lung Injury/M.C. Antkowiak, E.<br />
Dilli, A. Wallace, D. Distafano, L.P. Lalire, N. Ubags, M.E. Poynter,<br />
B.T. Suratt, Burlington, VT, p.A5674<br />
Abl Family Kinases Mediate LPS-Induced Lung Vascular<br />
Permeability and Inflammation/A.N. Rizzo, X. Sun, E. Letsiou,<br />
J.G.N. Garcia, S.M. Dudek, Chicago, IL, p.A5675<br />
Differential Effect of Low and High Magnitude Cyclic Stretch on<br />
Endothelial Inflammatory Activation/A. Sitikov, Y. Tian, I.<br />
Mambetsariev, G. Gawlak, J. O’Donnell, A.A. Birukova, Chicago, IL,<br />
p.A5676<br />
Many Roles of Vinculin in Regulation of Endothelial Monolayer<br />
Integrity: Location, Location, Location/Y. Ke, A.S. Shah, T. Ohmura,<br />
N. Sarich, A.A. Birukova, K.G. Birukov, Chicago, IL, p.A5677<br />
Multifunctional Regulator of Small GTPases IQGAP1 Mediates<br />
Lung Endothelial Response to Barrier Enhancing Oxidized<br />
Phospholipids/Y. Ke, O. Oskolkova, T. Ohmura, N. Sarich, K.G.<br />
Birukov, Chicago, IL, p.A5678<br />
E.N. Grayck, MD, Aurora, CO<br />
Actin Related Protein 2/3 Complex Regulates Actin Membrane<br />
Structures to Determine Endothelial Barrier Function/P.G.<br />
Belvitch, M. Brown, E. Letsiou, A.N. Rizzo, J.G.N. Garcia, S.M.<br />
Dudek, Chicago, IL, p.A5679<br />
VEGF Receptor-2 Mediates Adherens Junction Remodeling<br />
and Endothelial Permeability in Pulmonary EC Exposed to<br />
High Magnitude Cyclic Stretch/Y. Tian, Y. Ke, G. Gawlak, J.<br />
O’Donnell, A.A. Birukova, K.G. Birukov, Chicago, IL, p.A5680<br />
Inhibition of Hsp90 Repairs the LPS-Induced ALI in Mice/C.<br />
Birmpas, C. Dimitropoulou, N. Barabutis, G.S. Thangjam, B.W.<br />
Gregory, J.D. Catravas, Norfolk, VA, p.A5681<br />
Cytosolic Active Caspase 3 Plays a Critical Role in Promoting<br />
Endothelial Barrier Integrity/M. Damarla, K. Carino, K. Suresh, L.<br />
Johnston, B.S. Kim, T. Kolb, R.L. Damico, C. Machamer, L.<br />
Shimoda, P.M. Hassoun, Baltimore, MD, p.A5682<br />
Molecular Candidates for Promoting Pulmonary Vascular<br />
Endothelial Repair in Endotoxin-Induced Lung Injury/T.<br />
Kawasaki, T. Kinoshita, J. Terada, K. Tatsumi, Chiba, Japan,<br />
p.A5683<br />
Group V Secretory Phospholipase A2 Is Degraded by Autophagy<br />
in Human Lung Endothelial Cells/L.N. Meliton, X. Zhu, M. Brown,<br />
Y. Ephstein, E. Letsiou, S.M. Dudek, Chicago, IL, p.A5684<br />
TUESDAY MORNING<br />
ATS 2016 • San Francisco