Final Program
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TUESDAY • MAY 17 299<br />
P1339<br />
Erythropoietin Receptor (EPOR)/b-Common Receptor (b-CR)<br />
Signalling: A Potential Therapeutic Role in Lung Disease/K.<br />
Rochfort, S. Whelan, E. Coleman, K. Howell, Dublin, Ireland,<br />
p.A5844<br />
P1349<br />
Hydrogen Sulfide Attenuates Bronchial Epithelial Cell<br />
Apoptosis by Inhibiting Endoplasmic Reticulum Stress/<br />
Y. Chen, F. Lin, C. Liao, Y. Sun, Y. Bai, Y. Liao, M. Li, Y. Qi,<br />
Beijing, China, p.A5853<br />
P1340<br />
Interleukin-6 Trans-Signaling as a Therapeutic Target in<br />
Emphysema/B. Jenkins, S. Ruwanpura, L. McLeod, A. Lilja, L.<br />
Dousha, S. Bozinovski, P. King, P.G. Bardin, R. Vlahos, G.<br />
Anderson, S. Rose-John, Clayton, Australia, p.A5845<br />
P1350<br />
Expression and Function of MTUS1 in a Cell Model of Cigarette<br />
Smoke Extract Induced Chronic Obstructive Pulmonary<br />
Disease/X. Gong, J. Zhou, Y. Song, C. Bai, Shanghai, China,<br />
p.A5854<br />
P1341<br />
P1342<br />
ARA-290, an Erythropoietin Mimetic, Prevents the<br />
Development of Emphysema in the Adult Mouse Lung/S.<br />
Whelan, K. Rochfort, E. Coleman, P. McLoughlin, K. Howell,<br />
Dublin, Ireland, p.A5846<br />
Small-Molecule CFTR Modulators in Pre-Clinical Development<br />
for the Treatment of Chronic Obstructive Pulmonary Disease/L.<br />
Drew, J.P. Miller, O. Green, A. Villella, D. Kanmert, B. McEwan, C.<br />
Bastos, K. Longo, M. Ivarsson, B. Munoz, P.-S. Lee, H. Mehmet, M.<br />
Haeberlein, Cambridge, MA, p.A5847<br />
P1351<br />
P1352<br />
Role of Carcinoembryonic Antigen-Related Cell Adhesion<br />
Molecule 1 (CEACAM1) in Acute Exacerbation of Chronic<br />
Obstructive Pulmonary Disease and the Potential<br />
Mechanism/Y. Zhu, C. Bai, Y. Song, X. Wang, Shanghai, China,<br />
p.A5855<br />
Localization and Expression of Fam13a and Ireb2 in Mouse<br />
Lung Tissue/M. Sato, S. Inoue, A. Igarashi, Y. Tokairin, T.<br />
Nemoto, K. Sato, M. Kobayashi, Y. Abe, I. Kubota, Y. Shibata,<br />
Yamagata, Japan, p.A5856<br />
P1343<br />
C71<br />
Association of Increased Autophagy in COPD and<br />
Dysregulation of Zinc Handling Systems/E. Roscioli, H.<br />
Bac-Tran, R. Hamon, P. Zalewski, S.J. Hodge, Adelaide, Australia,<br />
p.A5848<br />
THEMATIC POSTER SESSION<br />
YOU ARE WHAT YOU BREATHE: AIRWAY CELL<br />
BIOLOGY IN COPD<br />
9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />
Viewing: Posters will be on display for entire session.<br />
Area L, Hall D (North Building, Lower Level)<br />
Discussion: 11:00-11:45: authors will be present for individual discussion<br />
11:45-12:45: authors will be present for discussion with assigned facilitators<br />
P1345<br />
Cellular Localization of Drug Transporter Protein in Human<br />
COPD Lung/X. Zhou, T. Berg, T. Hegelund-Myrback, M. Nord, L.<br />
Gustavsson, Molndal, Sweden, p.A5849<br />
P1346 Decreased Nuclear Factor Erythroid 2-Related Factor 2<br />
Expression Enhances Apoptosis of Airway Epithelial Cells in<br />
Patients with Chronic Obstructive Pulmonary Disease/K.<br />
Yamada, K. Asai, Y. Kubo, Y. Kyomoto, T. Kawamoto, S. Yoshida,<br />
K. Sato, N. Yamamoto, N. Yoshii, T. Watanabe, M. Uji, K. Hirata,<br />
Osaka, Japan, p.A5850<br />
P1347<br />
P1348<br />
Extracellular ATP Involves in dsRNA-Induced MUC5AC<br />
Production Via P2Y2R in Human Airway Epithelium/<br />
Y. Shishikura, A. Koarai, H. Sugiura, H. Aizawa, Y. Hashimoto, T.<br />
Numakura, M. Yamada, M. Ichinose, Sendai, Japan, p.A5851<br />
Role of Acrolein in Cigarette Smoke-Induced Cystic Fibrosis<br />
Transmembrane Conductance Regulator (CFTR)<br />
Dysfunction/V.Y. Lin, S.V. Raju, L. Tang, L. Wilson, M. Mazur, K.J.<br />
Macon, J.E. Trombley, P.L. Jackson, J.C. Kappes, L.J. DeLucas, S.<br />
Barnes, J.E. Blalock, S. Rowe, Birmingham, AL, p.A5852<br />
P1353<br />
P1354<br />
P1355<br />
P1356<br />
P1357<br />
P1358<br />
P1359<br />
P1360<br />
P1361<br />
P1362<br />
Quantification and Characterization of Human Lung<br />
Mesenchymal Stem Cells/T. Cruz, A. Lopez-Giraldo, A. Agusti, R.<br />
Faner, Barcelona, Spain, p.A5857<br />
Intercellular Adhesion Molecule 1 (ICAM-1) Expression Is<br />
Upregulated in Smokers and Patients with Chronic Airflow<br />
Limitation (CAL)/S.D. Shukla, H.K. Muller, R. Latham, S.S. Sohal,<br />
H. Walters, Hobart, Australia, p.A5858<br />
Induced-Pluripotent Stem Cell-Derived Mesenchymal Stem<br />
Cells Attenuate Cigarette Smoke-Induced Mitochondrial<br />
Dysfunction And Apoptosis in Airway Smooth Muscle Cells/X.<br />
Li, C. Michaeloudes, Y. Zhang, Q. Lian, J.C.W. Mak, P.K. Bhavsar,<br />
K.F. Chung, Hong Kong, Hong Kong Prc, p.A5859<br />
In Search of Ckit+ Stem Cells in Lung Tissue/A. Lopez-Giraldo,<br />
T. Cruz, A. Agusti, R. Faner, Barcelona, Spain, p.A5860<br />
Effects of Vilanterol and Umeclidinium Alone and in<br />
Combination in Human Airway Smooth Muscle Cells/N. Shaikh,<br />
M. Johnson, J. Riley, K.F. Chung, P.K. Bhavsar, London, United<br />
Kingdom, p.A5861<br />
Flavored E-liquids Alter Cell Proliferation and Calcium<br />
Signaling/T.R. Rowell, S. Sizer, R. Tarran, Chapel Hill, NC,<br />
p.A5862<br />
HMGA1 Permits Human Airway Basal Stem/Progenitor Cells to<br />
Regenerate the Normal Airway Epithelium/H. Zhang, J. Yang,<br />
M.S. Walters, R.G. Crystal, New York, NY, p.A5863<br />
The COPD Progression Is Mediated by Up-Regulated RAGE<br />
and Nuclear Translocation of Nrf2 Signaling/H. Lee, J.-R. Park,<br />
S.-R. Yang, Korea, Republic of, p.A5864<br />
Little Cigars Exert More Severe Effects on Airway Epithelia<br />
than Cigarettes/A. Ghosh, S.L. Reeber, C.M. Jania, A.J. Garrison,<br />
S.L. Lee, S.L. Tilley, C.M. Doerschuk, A.H. Herring, G.L. Glish, R.<br />
Tarran, Chapel Hill, NC, p.A5865<br />
Inhibition of Nephronectin Expression in Human Bronchial<br />
Epithelial Cells Using siRNA Knock-Down/G. Qian, A. Henry, B.<br />
Liu, S. Miller, C.K. Billington, I.P. Hall, Nottingham, United<br />
Kingdom, p.A5866<br />
TUESDAY MORNING<br />
ATS 2016 • San Francisco