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SUNDAY • MAY 15 55<br />

P727<br />

P728<br />

P729<br />

P730<br />

P731<br />

P732<br />

P733<br />

P734<br />

A40<br />

Both Eosinophilic and Neutrophilic Inflammation Were<br />

Associated with Pulmonary Function in Ex-Smokers with<br />

Asthma/T. Nagasaki, H. Matsumoto, T. Oguma, H. Inoue, T. Iwata,<br />

T. Tajiri, Y. Kanemitsu, Y. Izuhara, H. Sunadome, I. Ito, A. Niimi, M.<br />

Mishima, Kyoto, Japan, p.A1454<br />

Correlation Between Sputum Eosinophilia and Exhaled Nitric<br />

Oxide/J. Lee, J.-W. Paeng, D.-C. Choi, B.-J. Lee, Seoul, Korea,<br />

Republic of, p.A1455<br />

Patients with Difficult to Control Eosinophilic Granulomatosis<br />

with Polyangiitis of a Vasculitis Clinical Center in Sao Paulo,<br />

Brazil/E.P. Oliveira, J. Pinaffi, M.S. Tavares, L.K. Dourado, C.S.V.<br />

Barbas, Sao Paulo, Brazil, p.A1456<br />

Long-Term Outcome and Prognostic Factors of Chronic<br />

Eosinophilic Pneumonia: Fujiyama Cohort Study/Y. Suzuki, S.<br />

Imokawa, M. Toyoshima, K. Yokomura, H. Nakamura, S. Kuroishi,<br />

N. Koshimizu, Y. Ohyama, K. Furuhashi, T. Fujisawa, N. Enomoto,<br />

N. Inui, Y. Nakamura, T. Yamada, T. Shirai, M. Masuda, H.<br />

Hayakawa, T. Suda, Hamamatsu, Japan, p.A1457<br />

Fluid Shear Stress Modulates Changes in Cell Morphology in<br />

Human Eosinophils/K. Son, M. Small, L. Janssen, Hamilton,<br />

Canada, p.A1458<br />

Association Between Early Improvements in Lung Function<br />

and Asthma Control with Reslizumab and the Annual Rate of<br />

Asthma Exacerbations/E.D. Bateman, J. Zangrilli, M. Germinaro,<br />

S. Weiss, M. Castro, Cape Town, South Africa, p.A7782<br />

Effect of Reslizumab Treatment on Rescue Systemic<br />

Corticosteroid Use in Patients with Asthma and Elevated<br />

Blood Eosinophils: Results from a Pooled Analysis of Two<br />

Phase 3, Placebo-Controlled Trials/P. Bardin, K. Murphy, M.<br />

Garin, Melbourne, Australia, p.A7783<br />

The Circadian Clock Regulates Allergic Lung Inflammation:<br />

Implications for Asthma/H. Durrington, A. Loudon, D. Ray,<br />

Manchester, United Kingdom, p.A7784<br />

THEMATIC POSTER SESSION<br />

EPITHELIAL REGULATION OF INFLAMMATION<br />

9:00 a.m. - 4:15 p.m. MOSCONE CENTER<br />

Viewing: Posters will be on display for entire session.<br />

Area G, Hall D (North Building, Lower Level)<br />

Discussion: 11:00-11:45: authors will be present for individual discussion<br />

11:45-12:45: authors will be present for discussion with assigned facilitators<br />

Facilitator:<br />

P735<br />

P736<br />

R. Wu, PhD, Davis, CA<br />

The Effect of IL-13 and IL-33 on the Efficacy of Albuterol on<br />

Airway Hyperresponsiveness in a Mouse Model of<br />

Asthma/R.G. Townley, S. Agrawal, M.R. Hanna, B. Chang, N.<br />

Nettagul, Omaha, NE, p.A1459<br />

PERK Inhibition Improves Permeability in Mechanical<br />

Stretch-Induced Epithelial Injury/T. Dolinay, N. Yehya, G. Gray<br />

Lawrence, S.S. Margulies, Philadelphia, PA, p.A1460<br />

P737<br />

P738<br />

P739<br />

P740<br />

P741<br />

P742<br />

P743<br />

P744<br />

P745<br />

Facilitator:<br />

P746<br />

P747<br />

P748<br />

Heat-Shock Accelerates Human Lung Epithelial Wound<br />

Healing by Activating Expression of Fibroblast Growth Factor<br />

(FGF)-1: Implications for Idiopathic Pulmonary Fibrosis<br />

(IPF)/J.D. Hasday, R.G. Scheraga, C. Thompson, M. Tulapurkar,<br />

M.J. Cowan, J. Sun, R. Cai, C. Logun, N.W. Todd, J. Shelhamer,<br />

S.P. Atamas, I.G. Luzina, Baltimore, MD, p.A1461<br />

L-citrulline Prevents Asymmetric Di-methyl Arginine<br />

Uncoupling of Nitric Oxide Synthase in Primary Human Airway<br />

Epithelial Cells/D.E. Winnica, H. Grasemann, L.G. Que, B.<br />

Freeman, K. Wasil, S.E. Wenzel, F. Holguin, Pittsburgh, PA,<br />

p.A1462<br />

Intranasal Elastase Induces Mucus Accumulation and<br />

Alterations in Lung Mucus Proteome in Mice/J.A.<br />

Fernandez-Blanco, A. Ermund, A.M. Rodriguez-Pineiro, J. Root, C.<br />

McCrae, A. Astrand, G.C. Hansson, Molndal, Sweden, p.A1463<br />

Relationship of ER Stress to Type 2 Inflammation in<br />

Asthma/K.L. Jung, S.A. Christenson, S. Nerella, O.D. Solberg,<br />

C.P. Nguyen, P.G. Woodruff, N.R. Bhakta, San Francisco, CA,<br />

p.A1464<br />

TWEAK Induced Chemokine, MCP-1, RANTES and IL-8<br />

Production in Human Bronchial Epithelial Cells/K. Matsuno, N.<br />

Harada, A. Ishimori, S. Harada, T. Takeshige, J. Ito, R. Atsuta, K.<br />

Takahashi, Tokyo, Japan, p.A1465<br />

Histamine Stimulates Mucus Secretion Through IL-4 Induced<br />

TMEM16A in Human Nasal Epithelium/H.-J. Cho, Y.H. Lee, C.-H.<br />

Kim, J.-H. Yoon, Seoul, Korea, Republic of, p.A1466<br />

Regulation of Dipeptydyl Peptidase-4 (DPP4) Expression in<br />

Bronchial Epithelial Cells (BECs)/K. Chibana, T. Shiobara, T.<br />

Watanabe, Y. Horigane, A. Takemasa, Y. Ishii, Mibu Machi, Tochigi<br />

prefecture, Japan, p.A1467<br />

Chloride Ion Transport and Localization of TMEM16A in<br />

IL-13-Induced Goblet Cell Metaplasia/M. Kondo, K. Hara, M.<br />

Tsuji, K. Takeyama, E. Tagaya, J. Tamaoki, Tokyo, Japan, p.A1468<br />

Bronchial Epithelial Cells Expression of IL-17A and IL-17F in<br />

Asthma and COPD/T. Morimoto, S.G. Smith, J.P. Oliveria, S.<br />

Beaudin, A. Schlatman, K. Howie, C. Obminski, G. Nusca, R.<br />

Sehmi, G.M. Gauvreau, P.M. O’Byrne, Hamilton, Canada, p.A1469<br />

A.L. Linderholm, PhD, Davis, CA<br />

Airway Progenitor Clone Formation Is Enhanced by<br />

Y-27632-Dependent Changes in the Transcriptome/S.D.<br />

Reynolds, C. Rios, A. Wesolowska-Andersen, M. Pinter, C.<br />

Happoldt, G.M. Solomon, D.P. Nichols, M.A. Seibold, Columbus,<br />

OH, p.A1470<br />

Alternaria Alternata Induces Pulmonary Inflammation in In Vivo<br />

and In Vitro Models of Asthma: Relative Contribution of Th2<br />

Cytokines/K. Hilliard, M. Caniga, I. Kariv, R. De Waal Malefyt, H.<br />

Chen, M. Salmon, M. Cicmil, Boston, MA, p.A1471<br />

The Physiological Glucocorticoid (GC), Hydrocortisone, Limits<br />

Selected Actions of Synthetic GC in Human Airway<br />

Epithelium/D. Radojicic, C.R. Keenan, A.G. Stewart, Parkville,<br />

Australia, p.A1472<br />

SUNDAY MORNING<br />

ATS 2016 • San Francisco

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