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055699.full

055699.full

ioRxiv preprint first posted online May. 26, 2016; doi: http://dx.doi.org/10.1101/055699. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY 4.0 International license. Report of Partial Findings from the National Toxicology Program Carcinogenesis Studies of Cell Phone Radiofrequency Radiation in Hsd: Sprague Dawley® SD rats (Whole Body Exposures) Draft 5-19-2016 Table of Contents Abstract.......................................................................................................................................... 2 Summary........................................................................................................................................ 4 Study Rationale ............................................................................................................................. 5 Description of the NTP Cell Phone RFR Program .................................................................... 6 Study Design .................................................................................................................................. 7 Results ............................................................................................................................................ 8 Brain................................................................................................................................... 9 Heart................................................................................................................................. 10 Discussion..................................................................................................................................... 13 Conclusions.................................................................................................................................. 15 Next Steps .................................................................................................................................... 15 Appendix A – Contributors ........................................................................................................ 17 Appendix B – Statistical Analysis .............................................................................................. 18 Appendix C - Pathology .............................................................................................................. 21 Appendix D – Historical Controls ............................................................................................. 26 Appendix E – Time on Study to Appearance of Tumors ........................................................ 27 Appendix F – Reviewer’s Comments ........................................................................................ 29 Appendix G – NIH Reviewer’s Comments .............................................................................. 32 Appendix G1: Reviewer’s Comments ........................................................................... 33 Appendix G2: NTP’s Responses to NIH Reviewer’s Comments ............................... 65 1

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