INTENSIVE CARE
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directly proportional to the level of surfactant that is present in<br />
the newborn [85].<br />
A review evaluated outcomes in infants given synthetic<br />
surfactant (pre-ventilatory or post-ventilatory) compared<br />
with control treatment which consisted of intratracheal<br />
administration of normal saline or air placebo. The different<br />
types of synthetic surfactant used in these trials were<br />
DPPC plus high density lipoprotein, powdered DPPC and<br />
phosphatidylglycerol and DPPC plus phosphatidylglycerol in<br />
saline. Studies also compared surfactant [86] given as either<br />
multiple or single doses to infants who were either premature<br />
(