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051045.full

051045.full

ioRxiv preprint first posted online Apr. 29, 2016; doi: http://dx.doi.org/10.1101/051045. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-ND 4.0 International license. 1 How strongly does appetite counter weight loss? Quantification of the homeostatic control of human energy intake Authors: David Polidori 1 ; Arjun Sanghvi 2 ; Randy Seeley 3 ; Kevin D. Hall 2* Affiliations: 1 Janssen Research & Development, LLC, San Diego, CA; 2 National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD; 3 Department of Surgery, University of Michigan, Ann Arbor, MI. *To whom correspondence should be addressed: Kevin D. Hall, PhD National Institute of Diabetes & Digestive & Kidney Diseases National Institutes of Health 12A South Drive, Room 4007 Bethesda, MD 20892-5621 phone: 301-402-8248 fax: 301-402-0535 email: kevinh@niddk.nih.gov Revision Date: April 29, 2016. Word Count: 3904 Funding: This research was supported by the Intramural Research Program of the NIH, National Institute of Diabetes & Digestive & Kidney Diseases, using data from a study sponsored by Janssen Research & Development, LLC. Disclosure: D.P. is a full-time employee of Janssen Research & Development, LLC. K.D.H. reports patent pending on a method of personalized dynamic feedback control of body weight (US Patent Application No. 13/754,058; assigned to the NIH) and has received funding from the Nutrition Science Initiative to investigate the effects of ketogenic diets on human energy expenditure. R.S. is a paid consultant for Janssen, Novo

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