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ioRxiv preprint first posted online Nov. 25, 2016; doi: http://dx.doi.org/10.1101/089383. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. All rights reserved. No reuse allowed without permission. 1 A genetic risk score to guide age-specific, personalized prostate cancer screening Tyler M. Seibert, MD 1,2 Chun Chieh Fan, MD 1,3 Yunpeng Wang, PhD 4 Verena Zuber, PhD 4 Roshan Karunamuni, PhD 1,2 J. Kellogg Parsons, MD 5 Rosalind A. Eeles, PhD 6,7 Douglas F. Easton, PhD 8 ZSofia Kote-Jarai, PhD 6 Ali Amin Al Olama, PhD 8 Sara Benlloch Garcia, PhD 8 Kenneth Muir, PhD 9,10 Henrik Gronberg, Prof 11 Fredrik Wiklund, PhD 11 Markus Aly, PhD 11,12 Johanna Schleutker, PhD 13,14 Csilla Sipeky, PhD 15 Teuvo LJ Tammela, Prof 16 Børge G. Nordestgaard, Prof 17,18 Sune F. Nielsen, PhD 17,18 Maren Weischer, MD 18 Rasmus Bisbjerg, MD 19 M. Andreas Røder, MD 20 Peter Iversen, Prof 17,20 Tim J. Key, DPhil 21 Ruth C. Travis, DPhil 21 David E. Neal, FMedSci 22,23 Jenny L. Donovan, PhD 24 Freddie C. Hamdy, FMedSci 25 Paul Pharoah, Prof 26 Nora Pashayan, MD 27,26 Kay-Tee Khaw, FRCP 28 Christiane Maier, PhD 29 Walther Vogel, Prof 29 Manuel Luedeke, PhD 29 Kathleen Herkommer, MD 30 Adam S. Kibel, MD 31 Cezary Cybulski, MD 32 Dominika Wokolorczyk, PhD 32 Wojciech Kluzniak, MS 32 Lisa Cannon-Albright, PhD 33,34 Hermann Brenner, Prof 35,36,37

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