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How <strong>Abortion</strong> Kit Effectively works?<br />
• MTP Kit contains Mifepristone and Misoprostol as active ingredients.<br />
The anti-progest<strong>at</strong>ional activity of Mifepristone results from<br />
competitive interaction <strong>with</strong> progesterone <strong>at</strong> progesterone-receptor<br />
sites.<br />
• Misoprostol seems to inhibit gastric acid secretion by a direct action<br />
on the parietal cells through binding to the prostaglandin receptor.<br />
• The activity of this receptor is medi<strong>at</strong>ed by G proteins which normally<br />
activ<strong>at</strong>e adenyl<strong>at</strong>e cyclase. The indirect inhibition of adenyl<strong>at</strong>e cyclase<br />
by Misoprostol may be dependent on guanosine-5’-triphosph<strong>at</strong>e (GTP).<br />
• Misoprostol has also been shown to increase the amplitude and<br />
frequency of uterine contractions during pregnancy via selective<br />
binding to the EP-2/EP-3 prostanoid receptors.