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Treating Infantile Hemangiomas in Children

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Medic<strong>in</strong>e<br />

(Brand Name) How It Is Taken More Information<br />

Beta-Blockers<br />

Propranolol<br />

(Hemangeol)<br />

Timolol<br />

(Timoptic-XE®)<br />

Atenolol<br />

(Tenorm<strong>in</strong>®)<br />

Nadolol<br />

(Corgard®)<br />

Steroids<br />

Methylprednisolone<br />

(Medrol®)<br />

Prednisolone<br />

(Flo-Pred®, Prelone®)<br />

Triamc<strong>in</strong>olone<br />

(Kenalog®)<br />

Taken by mouth<br />

daily<br />

Gel drops put on<br />

the IH daily<br />

Taken by mouth<br />

daily<br />

Taken by mouth<br />

daily<br />

Shot given<br />

monthly **<br />

• Beta-blockers are used to treat many conditions, such as high<br />

blood pressure, irregular heartbeat, and migra<strong>in</strong>e headaches.<br />

• Propranolol (Hemangeol) is the first medic<strong>in</strong>e to be approved<br />

by the U.S. Food and Drug Adm<strong>in</strong>istration (FDA) for IHs.<br />

• Timolol (Timoptic-XE®) was made to treat glaucoma (an eye<br />

condition). Some health care professionals now use it to treat<br />

some types of IHs. *<br />

• Atenolol (Tenorm<strong>in</strong>®) and Nadolol (Corgard®) were made to<br />

treat high blood pressure. Some health care professionals may<br />

also use these medic<strong>in</strong>es to treat IHs. *<br />

• Steroids are used to treat many conditions, such as arthritis,<br />

asthma, and sk<strong>in</strong> conditions. Health care professionals have<br />

also used steroids to treat IHs. *<br />

* The FDA approves medic<strong>in</strong>es to treat certa<strong>in</strong> conditions. A health care professional may choose to prescribe a medic<strong>in</strong>e for a condition other<br />

than what the FDA has approved it for. This is called “off-label” use, and health care professionals often prescribe medic<strong>in</strong>es this way.<br />

** The number of shots needed to treat an IH depends on the specific type of IH your child has. Talk with your child’s health care professional<br />

about how many shots your child may need.<br />

What have researchers found about how well medic<strong>in</strong>es<br />

work to treat an IH?<br />

Beta-Blockers<br />

• Propranolol (Hemangeol) helps treat the IH <strong>in</strong> at least 9 out of<br />

every 10 children.<br />

»»<br />

Fewer than 2 out of every 10 children treated with propranolol<br />

(Hemangeol) needed additional propranolol treatment<br />

because the IH started to grow aga<strong>in</strong>.<br />

• Timolol (Timoptic-XE®) gel drops may help treat the IH <strong>in</strong> at<br />

least 6 out of every 10 children, but more research is needed to<br />

know this for sure.<br />

• Atenolol (Tenorm<strong>in</strong>®) and nadolol (Corgard®) may help treat IHs<br />

as well as propranolol (Hemangeol) does, but more research is<br />

needed to know this for sure.<br />

5

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