Artificial Blood Market Segments and Key Trends 2016-2024
According to the World Health Organization (WHO), there are about 50,000 stem cell transplantations performed annually worldwide. Nearly 2,000 cord blood hematopoietic stem cell transplants are performed annually worldwide. Use of stem cells from cord blood is increasing as it does not require perfect human leukocyte antigen (HLA) tissue matching, may be used allogenically and has less incidence of graft v/s host disease. According to the New York Blood Center (NYBC), which is the largest cord blood bank globally in terms of units stored, more than one half of all stem cell transplants in children, in the U.S., use cord blood. In Japan, on the other hand, similar is the statistic in the adult group.
According to the World Health Organization (WHO), there are about 50,000 stem cell transplantations performed annually worldwide. Nearly 2,000 cord blood hematopoietic stem cell transplants are performed annually worldwide. Use of stem cells from cord blood is increasing as it does not require perfect human leukocyte antigen (HLA) tissue matching, may be used allogenically and has less incidence of graft v/s host disease. According to the New York Blood Center (NYBC), which is the largest cord blood bank globally in terms of units stored, more than one half of all stem cell transplants in children, in the U.S., use cord blood. In Japan, on the other hand, similar is the statistic in the adult group.
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<strong>Artificial</strong> <strong>Blood</strong> <strong>Market</strong><br />
Global <strong>Market</strong> Analysis, Insights, <strong>Trends</strong>, <strong>and</strong><br />
Opportunity Inference, 2014-<strong>2024</strong><br />
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REPORT DESCRIPTION<br />
<strong>Artificial</strong> <strong>Blood</strong> <strong>Market</strong>: Overview<br />
<strong>Artificial</strong> blood is an artificially developed substitute for red blood cells. For<br />
decades, scientists have been trying to develop artificial blood from various<br />
sources <strong>and</strong> through different methods to address the shortage of blood for<br />
transfusions. Inadequate number of blood donors <strong>and</strong> the criticality of blood-type<br />
rejection have encouraged researchers to develop artificial blood, thus reducing<br />
the dependency on blood donors.<br />
Transfusion of red blood cells (RBCs) is a st<strong>and</strong>ard <strong>and</strong> indispensable therapy for<br />
anemic conditions. <strong>Blood</strong> transfusion process has progressed through various<br />
developments, including development of acid-citrate-dextrose blood preservation<br />
solution, <strong>and</strong> cloning of ABO gene. However, blood transfusion come with a high<br />
risk of infections. Recombinant erythropoietin stimulating agent therapy has been<br />
the prominent therapy in cases such as chronic kidney disease, <strong>and</strong> chronic anemic<br />
conditions. Yet in thrombotic <strong>and</strong> neoplastic complications, blood transfusion is the<br />
only option. Hence, RBC production from hematopoietic stem cells has been the<br />
focus of regenerative therapy, with major players investing billions of dollars in<br />
R&D related to this technique. However, the final product is yet to receive U.S.<br />
Food & Drug Administration (FDA) approval.<br />
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REPORT DESCRIPTION<br />
<strong>Artificial</strong> <strong>Blood</strong> <strong>Market</strong>: Development<br />
• There has been significant progress made in the global artificial blood market<br />
with respect to finding a suitable method to produce blood cells. Scientists have<br />
been trying to develop artificial blood from diverse molecules ranging from<br />
perfluorocarbons to hemoglobin. With the advent of research in stem cells,<br />
researchers began to develop RBCs from stem cells of cord blood. The<br />
enrollment for the first clinical trials of stem-cell based red blood cells began in<br />
2009. This study used stem cells from cord blood <strong>and</strong> adult bone marrow. The<br />
study was conducted at the Hematological Laboratory at the University of Paris<br />
VI.<br />
• A similar research conducted by scientists at the University of Bristol <strong>and</strong> the<br />
UK’s National Health Service (NHS) using stem cells from adult <strong>and</strong> umbilical cord<br />
blood has shown successful results from initial studies. The study is scheduled to<br />
enter clinical trials with 20 subjects in 2017. The focus of these trials is to provide<br />
special treatment for specific patient groups, rather than act as complete<br />
replacement for blood.<br />
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REPORT DESCRIPTION<br />
<strong>Artificial</strong> <strong>Blood</strong> <strong>Market</strong>: Future Outlook<br />
Cord blood stem cell transplantation has proved to be a successful therapy in<br />
treatment of around 70 diseases. Developing artificial blood can be of great aid to<br />
meet the dem<strong>and</strong>-supply gap in blood transfusion, more so considering the fact<br />
that finding compatible donors for sickle cell anemia <strong>and</strong> thalassemia patients is a<br />
mammoth task. Development of artificial blood could be the most viable solution<br />
to address the unmet needs among these patients. Continued investment in<br />
research <strong>and</strong> development is crucial for ensuring the commercial application of this<br />
technology, a very critical factor to contribute towards development of artificial<br />
blood market. Being a critical therapy for a severe life condition, the artificial blood<br />
market is expected to get a product in a decade or so.<br />
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