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Drug List Book

Pravachol (Pravastatin)

Pravachol (Pravastatin) PRAV-a-STAT-in Classification: HMG-CoA reductase inhibitor. IFU: Lower cholesterol and triglycerides in the blood. Action: sterically hinders the action of HMG-CoA reductase Dosage: 20mg, 40mg, 80mg; tabs. Route: P.O Adverse Reaction: Muscle pain, weakness, or tenderness, Fever, Lack of energy, Yellowing of the eyes or skin, Nausea, Pain in the upper right part of the stomach, Extreme fatigue or weakness, Dark-colored urine. Interactions: cyclosporine, clarithromycin, colchicine: Increased risk of myopathy. Page 138

Premarin (Conjugated Estrogens) KON-joo-gay-ted ES-troe-jenz Classification: Estrogen IFU:Vasomotor Symptoms Action: Reduce moderate to severe hot flashes Dosage: Tablets: 0.3 mg, o.625 mg, 0.9 mcg, 1.25 mg, 2.5 mg Route: P.O. Adverse Reaction: Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, pain or tenderness around the eyes and cheekbones, passing gas, shivering, Sweating, thick, white vaginal discharge with no odor or with a mild odor, tightness in the chest, trouble sleeping, unusual tiredness or weakness Interactions: Carbamazepine, fosphenytoin, phenobarbital, phenytoin, rifampin: decreased effectiveness of estrogen therapy. Page 139

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