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Drug List Book

Vesicare (Solifenacin)

Vesicare (Solifenacin) sol-i-FEN-a-sin Classification: Urinary Antispasmodic IFU: Overactive Bladder Action: Antagonizes muscarinic receptors, reducing urinary bladder smooth-muscle contractions Dosage: 5 mg, 10 mg Route: P.O. Adverse Reaction: dry eyes, dry throat, asthenia, bladder pain, bloody or cloudy urine, fever, painful urination, decrease in urine volume, swelling of lower legs, frequent urge to urinate Interactions: Anticholinergics: Increased frequency or severity of adverse reactions Page 180

Viagra (Sildenafil) sil-DEN-a-fil Classification: PDE-5 Inhibitor IFU: Erectile Dysfunction Action: Inhibits PDE5, enhancing the effects of nitric oxide released during sexual stimulation Dosage: Injection 10 mg, Tablets 20 mg Route: P.O. & I.V. Adverse Reaction: anxiety, insomnia, seizures, bladder pain, dizziness, cloudy or bloody urine, indigestion, pain on urination, stomach upset Interactions: Enzyme inducers, rifampin: Reduced sildenafil blood level Page 181

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