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Drug List Book

Zestoretic (Lisinopril/

Zestoretic (Lisinopril/ Hydrochlorothiazide) HYE-droe-KLOR-oh-THYE-a-zide / lye-SIN-oh-pril Classification: Angiotensin II Receptor Blockers (ARB)/Diuretic IFU: Hypertension Action: Unknown Dosage: 12.5 mg - 20 mg Route: P.O. Adverse Reaction: blurred vision, chills, cough Interactions: Spironolactone: May increase the levels of potassium in your blood, especially if you are dehydrated or have kidney disease, diabetes, heart failure, or if you are an older adult Page 193

Zestril, Prinivil (Lisinopril) lyse-IN-oh-pril Classification: ACE Inhibitor IFU: Hypertension Action: Inhibits conversion of angiotensin I to angiotensin II (a potent vasoconstrictor), decreasing systemic vascular resistance, blood pressure, preload, and afterload Dosage: 2.5 mg, 5 mg, 10 mg Route: P.O. Adverse Reaction: myalgia, fatigue, asthenia, dizziness, hypotension, hyperkalemia, increased blood urea nitrogen, and increased serum creatinine Interactions: Thiazides: Hypokalemia Page 194

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