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Drug List Book

Ciprodex (Ciprofloxacin/

Ciprodex (Ciprofloxacin/ Dexamethasone) SIP-roe-FLOX-a-sin/ dex-a-METH-a-sone Classification: Quinolone/Corticosteroid IFU: Bacterial External Ear Infection Action: Ciprofloxacin functions as a bactericide by interfering with DNA gyrase, an enzyme with a key role in the synthesis of bacterial DNA. Dexamethasone is used in combination in order to aid in the reducing inflammatory responses that often accompany bacterial infection. Dosage: 0.14 ml Route: Auricular Adverse Reaction: hypersensitivity, ear discomfort, rash, difficulty breathing, Interactions: None significant. Page 44/45

Cleocin (Clindamycin) klin-da-MYE-sin Classification: Lincomycin Antibiotic IFU: Bacterial Infection Action: Bacteriostatic or bactericidal based on drug level and susceptibility of organism; suppresses growth of susceptible organisms in sebaceous glands by blocking protein synthesis. Dosage: 1 %, 2 % Route: Topical, intravaginal Adverse Reaction: GI upset, vaginitis, abnormal liver function test results, irritation Interactions: Erythromycin: May antagonize clindamycin effect. Separate administration times. Page 46

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