11 months ago

Drug List Book

Coumadin (Warfarin)

Coumadin (Warfarin) WAR-far-in Classification: Vitamin K Antagonist IFU: Anticoagulation Action: Inhibits vitamin K-dependent activation of clotting factors II, VII, IX, X, formed in the liver. Dosage: 1 mg, 2 mg, 2.5 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7.5 mg, 10 mg Route: P.O., I.V. Adverse Reaction: headache, nausea, hematuria, jaundice, dermatitis, necrosis, fever, vomiting, cramps Interactions: Acetaminophen: May increase bleeding with long-term therapy (more than 2 weeks) at high doses (more than 2g/day) of acetaminophen Page 51

Cozaar (Losartan) loe-SAR-tan Classification: ARB IFU: Hypertension Action: An angiotensin II receptor agonist that inhibits the vasoconstricting and aldosterone-secreting effects of angiotensin II Dosage: 25 mg, 50 mg Route: P.O. Adverse Reaction: dizziness, insomnia, sinusitis, dyspepsia, muscle cramps, cough, upper respiratory infection Interactions: Potassium-sparing diuretics, potassium supplements: Possible hyperkalemia Page 52

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